Abstract：
:Horseradish peroxidase (HRP) mediates efficient conversion of many phenolic contaminants and thus has potential applications for pollution control. Such potentially important applications suffer however from the fact that the enzyme becomes quickly inactivated during phenol oxidation and polymerization. The work here provides the first experimental data of heme consumption and iron releases to support the hypothesis that HRP is inactivated by heme destruction. Product of heme destruction is identified using liquid chromatography with mass spectrometry. The heme macrocycle destruction involving deprivation of the heme iron and oxidation of the 4-vinyl group in heme occurs as a result of the reaction. We also demonstrated that heme consumption and iron releases resulting from HRP destruction are largely reduced in the presence of polyethylene glycol (PEG), providing the first evidence to indicate that heme destruction is effectively suppressed by co-dissolved PEG. These findings advance a better understanding of the mechanisms of HRP inactivation.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Mao L,Luo S,Huang Q,Lu Jdoi
10.1038/srep03126subject
Has Abstractpub_date
2013-11-04 00:00:00pages
3126issn
2045-2322pii
srep03126journal_volume
3pub_type
杂志文章abstract：:Isopods of the genus Idotea have an unusual ability to feed on algae containing high amounts of chemical defense molecules, such as species of the genera Fucus and Ulva. In this study, we compared gene expression patterns of Idotea balthica individuals fed with Fucus vesiculosus to individuals fed with Ulva lactuca. W...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-34937-z
更新日期：2018-11-14 00:00:00
abstract：:While safety of fasting therapy is debated in humans, extended fasting occurs routinely and safely in wild animals. To do so, food deprived animals like breeding penguins anticipate the critical limit of fasting by resuming feeding. To date, however, no molecular indices of the physiological state that links spontaneo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39008
更新日期：2016-12-19 00:00:00
abstract：:Animal gut harbors diverse microbes that play crucial roles in the nutrition uptake, metabolism, and the regulation of host immune responses. The intestinal microbiota homeostasis is critical for health but poorly understood. Probiotics Paracoccus marcusii DB11 and Bacillus cereus G19, and antibiotics florfenicol did ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05312-1
更新日期：2017-07-06 00:00:00
abstract：:Surface incident solar radiation (Rs) of reanalysis products is widely used in ecological conservation, agricultural production, civil engineering and various solar energy applications. It is of great importance to have a good knowledge of the uncertainty of reanalysis Rs products. In this study, we evaluated the Rs e...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60460-1
更新日期：2020-02-26 00:00:00
abstract：:Light-sheet microscopy enables considerable speed and phototoxicity gains, while quantitative-phase imaging confers label-free recognition of cells and organelles, and quantifies their number-density that, thermodynamically, is more representative of metabolism than size. Here, we report the fusion of these two imagin...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76730-x
更新日期：2020-11-19 00:00:00
abstract：:In this report, we propose and demonstrate an air-mode photonic crystal ring resonator (PhCRR) on silicon-on-insulator platform. Air mode is utilized to confine the optical field into photonic crystal (PhC) air holes, which is confirmed by the three-dimensional finite-difference time-domain simulation. PhCRR structure...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19999
更新日期：2016-01-28 00:00:00
abstract：:This corrects the article DOI: 10.1038/srep44499. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/srep46959
更新日期：2018-03-19 00:00:00
abstract：:How diverse adult stem and progenitor populations regenerate tissue following damage to the brain is poorly understood. In highly regenerative vertebrates, such as zebrafish, radial-glia (RG) and neuro-epithelial-like (NE) stem/progenitor cells contribute to neuronal repair after injury. However, not all RG act as neu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40734-z
更新日期：2019-03-14 00:00:00
abstract：:On the basis of diet induced obesity and KO mice models, nitric oxide is implied to play an important role in the initiation of dyslipidemia induced insulin resistance. However, outcomes using iNOS KO mice have so far remained inconclusive. The present study aimed to assess IR in iNOS KO mice after 5 weeks of LFD feed...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41009
更新日期：2017-01-20 00:00:00
abstract：:Perturbations in lipid metabolic pathways to meet the bioenergetic and biosynthetic requirements is a principal characteristic of cancer cells. Sphingolipids (SPLs) are the largest class of bioactive lipids associated to various aspects of tumorigenesis and have been extensively studied in cancer cell lines and experi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-61283-w
更新日期：2020-03-13 00:00:00
abstract：:Chronic inflammation can be a major driver of the failure of a variety of organs, including chronic kidney disease (CKD). The NLR family pyrin domain-containing 3 (NLRP3) inflammasome has been shown to play a pivotal role in inflammation in a mouse kidney disease model. Nuclear factor erythroid 2-related factor 2 (Nrf...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08054-2
更新日期：2017-08-18 00:00:00
abstract：:The roles of CD4 + T cells and CD8 + T cells in hepatitis B virus (HBV) infection have been well documented. However, the role of innate immunity in HBV infection remains obscure. Here we examined the effect of activation of innate immunity by polyinosinic: polycytidylic acid (PolyI:C) on HBV infection. A chronic HBV ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00387-2
更新日期：2017-03-22 00:00:00
abstract：:The stinging capsules of cnidarians, nematocysts, function as harpoon-like organelles with unusual biomechanical properties. The nanosecond discharge of the nematocyst requires a dense protein network of the capsule structure withstanding an internal pressure of up to 150 bar. Main components of the capsule are short ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25709
更新日期：2016-05-11 00:00:00
abstract：:This study aimed to assess the validity and functional relevance of a standardized procedure to assess lower limb muscle power by means of the 30-s sit-to-stand (STS) test when compared to leg extension power (LEP), traditional STS performance and handgrip strength. A total of 628 community-dwelling older subjects (60...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73395-4
更新日期：2020-10-01 00:00:00
abstract：:Denitrification in coastal sediments can provide resilience to eutrophication in estuarine ecosystems, but this key ecosystem function is impacted directly and indirectly by increasing stressors. The erosion and loading of fine sediments from land, resulting in sedimentation and elevated sediment muddiness, presents a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-54192-0
更新日期：2019-11-26 00:00:00
abstract：:Calcium (Ca) deficiency in cabbage plants induces oxidative damage, hampering growth and decreasing quality, however, it is hypothesized that silicon (Si) added to the nutrient solution may alleviate crop losses. Therefore, this study aims at evaluating whether silicon supplied in the nutrient solution reduces, in fac...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80934-6
更新日期：2021-01-19 00:00:00
abstract：:Animals that experience situations likely to induce negative emotions show changes in judgment associated with pessimism. Few studies have focused on whether animals express stable differences in pessimism and whether these differences are related to personality traits. The first aim of this study was to explore if da...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17214-3
更新日期：2018-01-23 00:00:00
abstract：:Other than hard bones and shells, it is rare for soft tissues to fossilize, but occasionally they are well-preserved in amber. Here, we focus on both modern and fossilized species of the land snail superfamily Cyclophoroidea. Phylogenetic relationships within the Cyclophoroidea were previously studied using extant spe...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-51840-3
更新日期：2019-11-04 00:00:00
abstract：:Superdirective antennas developed over the last century have received renewed interest in recent years from the development of metamaterials. These arrays of electromagnetic resonators (or meta-atoms) carrying short wavelength electro- and/or magneto-inductive waves support current distributions with very high spatial...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56988-6
更新日期：2020-01-14 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 杂志文章,已发布勘误
doi：10.1038/s41598-017-17040-7
更新日期：2017-12-05 00:00:00
abstract：:Whole-genome sequencing is likely to become increasingly used by local clinical microbiology laboratories, where sequencing volume is low compared with national reference laboratories. Here, we describe a universal protocol for simultaneous DNA extraction and sequencing of numerous different bacterial species, allowin...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80031-8
更新日期：2021-01-08 00:00:00
abstract：:The Morris Water Maze is a widely used task in studies of spatial learning with rodents. Classical performance measures of animals in the Morris Water Maze include the escape latency, and the cumulative distance to the platform. Other methods focus on classifying trajectory patterns to stereotypical classes representi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep14562
更新日期：2015-10-01 00:00:00
abstract：:The Disc Agarose Channel (DAC) system utilizes microfluidics and imaging technologies and is fully automated and capable of tracking single cell growth to produce Mycobacterium tuberculosis (MTB) drug susceptibility testing (DST) results within 3~7 days. In particular, this system can be easily used to perform DSTs wi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26419-z
更新日期：2018-06-05 00:00:00
abstract：:Recent experimental work in the field of synthetic protocell biology has shown that prebiotic vesicles are able to 'steal' lipids from each other. This phenomenon is driven purely by asymmetries in the physical state or composition of the vesicle membranes, and, when lipid resource is limited, translates directly into...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05675
更新日期：2014-07-14 00:00:00
abstract：:Previous studies of protein fold space suggest that fold coverage is plateauing. However, sequence sampling has been -and remains to a large extent- heavily biased, focusing on culturable phyla. Sustained technological developments have fuelled the advent of metagenomics and single-cell sequencing, which might correct...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep14717
更新日期：2015-10-05 00:00:00
abstract：:Nonalcoholic fatty liver disease (NAFLD) is a rising cause of hepatocellular carcinoma (HCC). We examined whether inherited pathogenic variants in candidate genes (n = 181) were enriched in patients with NAFLD-HCC. To this end, we resequenced peripheral blood DNA of 142 NAFLD-HCC, 59 NAFLD with advanced fibrosis, and ...
journal_title：Scientific reports
pub_type： 杂志文章,多中心研究
doi：10.1038/s41598-019-39998-2
更新日期：2019-03-06 00:00:00
abstract：:Understanding and manipulating the dynamic properties of the magnetic vortices stabilized in patterned ferromagnetic structures are of great interest owing to the superior resonant features with the high thermal stability and their flexible tunability. So far, numerous methods for investigating the dynamic properties ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep17922
更新日期：2015-12-09 00:00:00
abstract：:Pharmaceutical applications of methylene blue, especially as photosensitizer, have been limited due to its rapid enzymatic reduction in the biological systems. In this study nano-platelet zirconium phosphate was synthesized and its biocompatibility was evaluated. The synthesized material was considered as drug deliver...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-51359-7
更新日期：2019-10-17 00:00:00
abstract：:Telomerase is a ribonucleoprotein enzyme, which maintains genome integrity in eukaryotes and ensures continuous cellular proliferation. Telomerase holoenzyme from the thermotolerant yeast Hansenula polymorpha, in addition to the catalytic subunit (TERT) and telomerase RNA (TER), contains accessory proteins Est1 and Es...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-68107-x
更新日期：2020-07-06 00:00:00
abstract：:The family Trichomycteridae is one of the most diverse groups of freshwater catfishes in South and Central America with eight subfamilies, 41 genera and more than 300 valid species. Its members are widely distributed throughout South America, reaching Costa Rica in Central America and are recognized by extraordinary a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-59519-w
更新日期：2020-02-14 00:00:00
