Abstract:
:A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Aponte-Santamaría C,Fischer G,Båth P,Neutze R,de Groot BLdoi
10.1038/s41598-017-17040-7subject
Has Abstractpub_date
2017-12-05 00:00:00pages
17201issue
1issn
2045-2322pii
10.1038/s41598-017-17040-7journal_volume
7pub_type
杂志文章,已发布勘误abstract::The flagellum is a rotary motor that enables bacteria to swim in liquids and swarm over surfaces. Numerous global regulators control flagellar assembly in response to cellular and environmental factors. Previous studies have also shown that flagellar assembly is affected by the growth-rate of the cell. However, a syst...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41189
更新日期:2017-01-24 00:00:00
abstract::Classification of histologic patterns in lung adenocarcinoma is critical for determining tumor grade and treatment for patients. However, this task is often challenging due to the heterogeneous nature of lung adenocarcinoma and the subjective criteria for evaluation. In this study, we propose a deep learning model tha...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40041-7
更新日期:2019-03-04 00:00:00
abstract::Sunitinib (ST), a multitargeted receptor tyrosine kinase inhibitor, has been demonstrated to be effective for the treatment of renal carcinoma. It has been reported that ST is involved in the mediation of autophagy; however, its regulatory role in the autophagic process remains controversial. Furthermore, the mechanis...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-47597-4
更新日期:2019-07-31 00:00:00
abstract::Distance decay principles predict that species with larger geographic ranges would have greater intraspecific genetic diversity than more restricted species. However, invasive pest species may not follow this prediction, with confounding implications for tracking phenomena including original ranges, invasion pathways ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63973-x
更新日期:2020-04-23 00:00:00
abstract::Fast volumetric microscopy is required to monitor large-scale neural ensembles with high spatio-temporal resolution. Widefield fluorescence microscopy can image large 2D fields of view at high resolution and speed while remaining simple and costeffective. A focal sweep add-on can further extend the capacity of widefie...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-26240-8
更新日期:2018-05-21 00:00:00
abstract::Although the association between visual acuity (VA) and vision-related quality of life (VRQoL) has been well reported in patients with type 2 diabetes mellitus (T2DM), little is known about how unilateral and bilateral VA affects daily performance in such patients. For this cross-sectional study, patients were recruit...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79483-9
更新日期:2021-01-11 00:00:00
abstract::Advances in Big Data make it possible to make short-term forecasts for market trends from previously unexplored sources. Trading strategies were recently developed by exploiting a link between the online search activity of certain terms semantically related to finance and market movements. Here we build on these earli...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50131-1
更新日期:2019-09-18 00:00:00
abstract::BMPs are multifunctional growth factors implicated in regulating the ovarian function as key intra-ovarian factors. Biological effects of BMPs are mediated through binding with membrane bound receptors like BMPR-IB and initiating downstream Smad signaling pathway. FecB mutation, regarded as a loss of function mutation...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-77596-9
更新日期:2020-11-24 00:00:00
abstract::Cancer cachexia is a complex multi-organ syndrome characterized by body weight loss, weakness, muscle atrophy and fat depletion. With a prevalence of 1 million people in Europe and only limited therapeutic options, there is a high medical need for new approaches to treat cachexia. Our latest results highlighted microb...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30569-5
更新日期:2018-08-17 00:00:00
abstract::Apterous (Ap), the best studied LIM-homeodomain transcription factor in Drosophila, cooperates with the cofactor Chip (Chi) to regulate transcription of specific target genes. Although Ap regulates various developmental processes, its function in the adult brain remains unclear. Here, we report that Ap and Chi in the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37255
更新日期:2016-11-17 00:00:00
abstract::Dumbbell probe (DP) attracts increasing interests in rolling circle amplification (RCA). A universal DP production method through cleavage-ligation of hairpin was proposed and optimized. The production is characterized by restriction endonuclease (RE)-induced cleavage ends ligation. It has the advantage of phosphoryla...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29229
更新日期:2016-07-07 00:00:00
abstract::Indoor simulation experiment was carried out to evaluate the formation and consumption rates of methane (CH4) in Xiangxi Bay of the Three Gorges Reservoir (TGR), China. The results show that both the CH4 formation and consumption rates were significantly positively correlated with temperature. CH4 efflux decreased wit...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep04449
更新日期:2014-03-24 00:00:00
abstract::Recent whole-exome sequencing (WES) studies demonstrated that TRAIP is associated with primordial dwarfism. Although TRAIP was partially studied in mitosis, its function in oocyte meiosis remained unknown. In this study, we investigated the roles of TRAIP during mouse oocyte meiosis. TRAIP was stably expressed during ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29735
更新日期:2016-07-11 00:00:00
abstract::With the development and application of nanotechnology, large amounts of nanoparticles will be potentially released to the environment and possibly cause many severe health problems. Although the toxicity of nanoparticles has been investigated, prevention and treatment of damages caused by nanoparticles have been rare...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02770-5
更新日期:2017-06-06 00:00:00
abstract::Laparoscopic experience and relevant reports about PD catheter emplacement in Chinese patients are seldom. In this study, we described our experience with advanced laparoscopy for PD catheter implantation in Chinese patients. There were one hundred and thirty Chinese patients accepted advanced laparoscopic approach fo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09596-1
更新日期:2017-08-22 00:00:00
abstract::Although most papillary thyroid carcinomas (PTCs) have a good prognosis, a small but certain fraction shows aggressive behavior. Therefore, a novel and well-performing molecular marker is needed. In the present study, we assessed the impact of the combination of the TERT promoter/BRAF mutations and Ki-67 labeling inde...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41752
更新日期:2017-02-02 00:00:00
abstract::Copy number variation (CNV) is a newly discovered form of intra-species genetic polymorphism that is defined as deletions or duplications of genome segments ranging from 1 kbp to several Mbp. CNV accounts for the majority of the genetic variation observed in humans (CNV regions cover more than 10% of the human genome)...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31340
更新日期:2016-08-11 00:00:00
abstract::This work describes a simple technique to produce porous ceramics with aligned porosity having very high permeability and specific surface area. SiOC-based compositions were processed from blends of three types of preceramic polymer and a catalyst, followed by curing and pyrolysis. The heating applied from the bottom ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41049
更新日期:2017-01-20 00:00:00
abstract::While neurofilament light chain (NfL) measurement in serum is a well-established marker of neuroaxonal damage in multiple sclerosis (MS), data on astroglial markers in serum are missing. In our study, glial fibrillary acid protein (GFAP) and NfL were measured in cerebrospinal fluid (CSF) and serum of MS patients and p...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33158-8
更新日期:2018-10-04 00:00:00
abstract::Invasive alien species are regarded a nuisance. This extends into a lack of conservation efforts in their native range. As a consequence, conservation of e.g. range-edge populations is neglected. Gobiidae have many representatives of alien species in European freshwaters, and therefore they have a bad reputation. Obje...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56264-7
更新日期:2019-12-23 00:00:00
abstract::Excessive activation of inflammation and the accompanying lung vascular endothelial barrier disruption are primary pathogenic features of acute lung injury (ALI). Microtubule-associated protein 4 (MAP4), a tubulin assembly-promoting protein, is important for maintaining the microtubule (MT) cytoskeleton and cell-cell ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08895
更新日期:2015-03-09 00:00:00
abstract::The continuous search for natural products that attenuate age-related losses has increasingly gained notice; among them, those applicable for skin care have drawn significant attention. The bioester generated from the Chenopodium quinoa's oil is a natural-origin ingredient described to produce replenishing skin effect...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76325-6
更新日期:2020-11-10 00:00:00
abstract::Immune responses are critical for defense against pathogens. However, prolonged viral infection can result in defective T cell immunity, leading to chronic viral infection. We studied immune activation in response to arenavirus infection during cholestasis using bile duct ligation (BDL). We monitored T cell responses,...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30627-y
更新日期:2018-08-15 00:00:00
abstract::The analysis of the choroid in the eye is crucial for our understanding of a range of ocular diseases and physiological processes. Optical coherence tomography (OCT) imaging provides the ability to capture highly detailed cross-sectional images of the choroid yet only a very limited number of commercial OCT instrument...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49816-4
更新日期:2019-09-16 00:00:00
abstract::Electromyography (EMG) is the standard technology for monitoring muscle activity in laboratory environments, either using surface electrodes or fine wire electrodes inserted into the muscle. Due to limitations such as cost, complexity, and technical factors, including skin impedance with surface EMG and the invasive n...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41860-4
更新日期:2019-04-03 00:00:00
abstract::The expansion of agriculture is shrinking pristine forest areas worldwide, jeopardizing the persistence of their wild inhabitants. The Udzungwa red colobus monkey (Procolobus gordonorum) is among the most threatened primate species in Africa. Primarily arboreal and highly sensitive to hunting and habitat destruction, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14862
更新日期:2015-10-07 00:00:00
abstract::The purpose of this paper is to develop a lightweight apron that will be used for shielding low intensity radiation in medical imaging radiography room and to apply it to a custom-made effective shielding. The quality of existing aprons made for protecting our bodies from direct radiation are improved so that they are...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27721
更新日期:2016-07-27 00:00:00
abstract::In this work, TiN film deposited by plasma enhanced atomic layer deposition (PEALD) is adopted to modify the commercial anatase TiO2 powders. A series of analyses indicate that the surface modification of 20, 50 and 100 cycles of TiN by PEALD does not change the morphology, crystal size, lattice parameters, and surfac...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30726-w
更新日期:2018-08-14 00:00:00
abstract::Photobiomodulation-based (LLLT) therapies show tantalizing promise for treatment of skin diseases. Confidence in this approach is blighted however by lamentable inconsistency in published experimental designs, and so complicates interpretation. Here we interrogate the appropriateness of a range of previously-reported ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02802-0
更新日期:2017-06-05 00:00:00
abstract::It is our contention that for multiscale modelling of infectious disease systems to evolve and expand in scope, it needs to be founded on a theory. Such a theory would improve our ability to describe infectious disease systems in terms of their scales and levels of organization, and their inter-relationships. In this ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52820-3
更新日期:2019-11-08 00:00:00