SERPINB3 is associated with longer survival in transgenic mice.

abstract：:We describe how an ensemble of four-level atoms in the diamond-type configuration can be applied to create a fully controllable effective coupling between two cavity modes. The diamond-type configuration allows one to use a bimodal cavity that supports modes of different frequencies or different circular polarisations...

journal_title：Scientific reports

authors： Chimczak G,Bartkiewicz K,Ficek Z,Tanaś R

更新日期：2018-10-03 00:00:00

abstract：:In applications involving large tissue specimens that have been sectioned into smaller tissue fragments, manual reconstruction of a "pseudo whole-mount" histological section (PWMHS) can facilitate (a) pathological disease annotation, and (b) image registration and correlation with radiological images. We have previous...

journal_title：Scientific reports

authors： Penzias G,Janowczyk A,Singanamalli A,Rusu M,Shih N,Feldman M,Stricker PD,Delprado W,Tiwari S,Böhm M,Haynes AM,Ponsky L,Viswanath S,Madabhushi A

更新日期：2016-07-26 00:00:00

abstract：:Advanced glycation end products (AGEs) play a key role in the progression of heart failure. Whether treatments limiting AGEs formation would prevent adverse left ventricular remodeling after myocardial infarction (MI) remain unknown. We investigated whether pyridoxamine (PM) could limit adverse cardiac outcome in MI. ...

journal_title：Scientific reports

authors： Deluyker D,Ferferieva V,Driesen RB,Verboven M,Lambrichts I,Bito V

更新日期：2017-11-22 00:00:00

abstract：:During the late Eocene, the Earth's climate experienced several transient temperature fluctuations including the Vonhof cooling event (C16n.1n; ~35.8 Ma) hitherto known mainly from the southern oceans. Here we reconstruct sea-surface temperatures (SST) and provide δ18O and δ13C foraminiferal records for the late Eocen...

journal_title：Scientific reports

authors： Śliwińska KK,Thomsen E,Schouten S,Schoon PL,Heilmann-Clausen C

更新日期：2019-03-14 00:00:00

abstract：:Shoulder apprehension is more complex than a pure mechanical problem of the shoulder, creating a scar at the brain level that prevents the performance of specific movements. Surgery corrects for shoulder instability at the physical level, but a re-dislocation within the first year is rather common. Predicting which pa...

journal_title：Scientific reports

authors： Zanchi D,Cunningham G,Lädermann A,Ozturk M,Hoffmeyer P,Haller S

更新日期：2017-03-29 00:00:00

abstract：:The high-speed liquid-jet velocity achieved using an injector strongly depends on the piston motion, physical property of the liquid, and container shape of the injector. Herein, we investigate the liquid ejection mechanism and a technique for estimating the ejection velocity of a high-speed liquid jet using a pyro je...

journal_title：Scientific reports

authors： Takagaki N,Kitaguchi T,Iwayama M,Shinoda A,Kumamaru H,Honda I

更新日期：2019-12-27 00:00:00

abstract：:Many environmental flow (e-flow) studies and applications have predominantly used state-(i.e., at a single time point) and rate-(i.e., temporal change) based demographic characteristics of species representing lower trophic levels (e.g., fish communities) to build flow-ecology relationships, rather than using a proces...

journal_title：Scientific reports

authors： Paudel S,Koprowski JL,Thakuri U,Sigdel R,Gautam RC

更新日期：2020-12-18 00:00:00

abstract：:Macroautophagy, the degradation of cytoplasmic content by lysosomal fusion, is an evolutionary conserved process promoting homeostasis and intracellular defence. Macroautophagy is initiated primarily by a complex containing ULK1 or ULK2 (two paralogs of the yeast Atg1 protein). To understand the differences between UL...

journal_title：Scientific reports

authors： Demeter A,Romero-Mulero MC,Csabai L,Ölbei M,Sudhakar P,Haerty W,Korcsmáros T

更新日期：2020-07-02 00:00:00

abstract：:The volcanic eruption of Santorini in the Bronze Age left detectable debris across the Mediterranean, serving as an anchor in time for the region, synchronizing chronologies of different sites. However, dating the eruption has been elusive for decades, as radiocarbon indicates a date about a century earlier than archa...

journal_title：Scientific reports

authors： Ehrlich Y,Regev L,Boaretto E

更新日期：2021-01-12 00:00:00

abstract：:Reprogramming of somatic cells has become a versatile tool for biomedical research and for regenerative medicine. In the current study, we show that manipulating alternative splicing (AS) is a highly potent strategy to produce cells for therapeutic applications. We demonstrate that silencing of hTAF4-TAFH activity of ...

journal_title：Scientific reports

authors： Kazantseva J,Sadam H,Neuman T,Palm K

更新日期：2016-08-08 00:00:00

abstract：:The large spin Hall effect in topological insulators (TIs) is very attractive for ultralow-power spintronic devices. However, evaluation of the spin Hall angle and spin-orbit torque (SOT) of TIs is usually performed on high-quality single-crystalline TI thin films grown on dedicated III-V semiconductor substrates. Her...

journal_title：Scientific reports

authors： Khang NHD,Nakano S,Shirokura T,Miyamoto Y,Hai PN

更新日期：2020-07-22 00:00:00

abstract：:Recent skin metagenomic studies have investigated the harbored viral diversity and its possible influence on healthy skin microbial populations, and tried to establish global patterns of skin-phage evolution. However, the detail associated with the phages that potentially play a role in skin health has not been invest...

journal_title：Scientific reports

authors： van Zyl LJ,Abrahams Y,Stander EA,Kirby-McCollough B,Jourdain R,Clavaud C,Breton L,Trindade M

更新日期：2018-08-16 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia characterized by the formation of amyloid plaques (Aβ). Over the last decade, the important role of the innate immune system for the disease development has been established. Chronic activation of microglial cells creates a proinflammatory environment, which...

journal_title：Scientific reports

authors： Boza-Serrano A,Yang Y,Paulus A,Deierborg T

更新日期：2018-01-24 00:00:00

abstract：:A central challenge in designing and administering effective anticoagulants is achieving the proper therapeutic window and dosage for each patient. The Hill coefficient, nH, which measures the steepness of a dose-response relationship, may be a useful gauge of this therapeutic window. We sought to measure the Hill coe...

journal_title：Scientific reports

authors： Chang JB,Quinnies KM,Realubit R,Karan C,Rand JH,Tatonetti NP

更新日期：2016-07-21 00:00:00

abstract：:Measurement-based quantum computing is one of the most promising quantum computing models. Although various universal resource states have been proposed so far, it was open whether only two Pauli bases are enough for both of universal measurement-based quantum computing and its verification. In this paper, we construc...

journal_title：Scientific reports

authors： Takeuchi Y,Morimae T,Hayashi M

更新日期：2019-09-19 00:00:00

abstract：:Increased activity of brown adipose tissue (BAT) activity in adults is thought to prevent obesity. Therefore, regulators of BAT activity might serve as anti-obesity therapy in future, but are not investigated thoroughly up to now. In our study, we assessed retrospectively the association of BAT activity with several e...

journal_title：Scientific reports

authors： Brendle C,Stefan N,Stef I,Ripkens S,Soekler M,la Fougère C,Nikolaou K,Pfannenberg C

更新日期：2019-02-13 00:00:00

abstract：:Molecular taxonomy often uncovers cryptic species, reminding us that taxonomic incompleteness is even more severe than previous thought. The importance of cryptic species for conservation is poorly understood. Although some cryptic species may be seriously threatened or otherwise important, they are rarely included in...

journal_title：Scientific reports

authors： Delić T,Trontelj P,Rendoš M,Fišer C

更新日期：2017-06-13 00:00:00

abstract：:The effect of resistin (RETN) on the response to anti-HCV therapy remains unclear. A prospective cohort study was performed using 655 consecutive HCV patients, of whom 513 had completed a course of interferon-based therapy. Multivariate and GEE analyses revealed four RETN single-nucleotide polymorphisms (SNPs), rs3486...

journal_title：Scientific reports

authors： Chang ML,Liang KH,Ku CL,Lo CC,Cheng YT,Hsu CM,Yeh CT,Chiu CT

更新日期：2016-08-01 00:00:00

abstract：:Pancreatic adenocarcinoma upregulated factor (PAUF) is a ligand of toll-like receptors (TLRs) and has been reported to be involved in pancreatic tumor development. However, the significance of PAUF expression in epithelial ovarian cancer remains unclear. We aimed to investigate the possible clinical significance of PA...

journal_title：Scientific reports

authors： Choi CH,Kang TH,Song JS,Kim YS,Chung EJ,Ylaya K,Kim S,Koh SS,Chung JY,Kim JH,Hewitt SM

更新日期：2018-08-15 00:00:00

abstract：:Urothelial carcinoma (UC) is a common disease causing significant morbidity and mortality as well as considerable costs for health systems. Extensive aberrant methylation of DNA is broadly documented in early UC, contributing to genetic instability, altered gene expression and tumor progression. However the triggers i...

journal_title：Scientific reports

authors： Erichsen L,Seifert HH,Schulz WA,Hoffmann MJ,Niegisch G,Araúzo-Bravo MJ,Bendhack ML,Poyet C,Hermanns T,Beermann A,Hassan M,Theis L,Mahmood W,Santourlidis S

更新日期：2020-03-02 00:00:00

abstract：:Patients who undergo orthotopic liver transplantation often sustain acute kidney injury(AKI). The toll-like receptor 4(TLR4)/Nuclear factor-кB(NF-кB) pathway plays a role in AKI. Dexmedetomidine(Dex) has been shown to attenuate AKI. The current study aimed to determine whether liver transplantation-induced AKI is asso...

journal_title：Scientific reports

authors： Yao H,Chi X,Jin Y,Wang Y,Huang P,Wu S,Xia Z,Cai J

更新日期：2015-11-20 00:00:00

abstract：:Uveitis, the pathologic condition of inflammation of the uvea, frequently leads to severe vision loss and blindness. S100A8 is a calcium-binding protein which mainly expresses in granulocytes and monocytes and plays a prominent role in the regulation of inflammatory processes and immune response. Here, we determined t...

journal_title：Scientific reports

authors： Wang Y,Zhang Z,Zhang L,Li X,Lu R,Xu P,Zhang X,Dai M,Dai X,Qu J,Lu F,Chi Z

更新日期：2016-10-27 00:00:00

abstract：:We study Coulomb interacting electrons confined in polygonal quantum rings. We focus on the interplay of localization at the polygon corners and Coulomb repulsion. Remarkably, the Coulomb repulsion allows the formation of in-gap states, i.e., corner-localized states of electron pairs or clusters shifted to energies th...

journal_title：Scientific reports

authors： Sitek A,Ţolea M,Niţă M,Serra L,Gudmundsson V,Manolescu A

更新日期：2017-01-10 00:00:00

abstract：:Acute chest syndrome (ACS) is a major complication of sickle cell anaemia (SCA) and a leading cause for hospital admissions and death. We aimed to study the spectrum of clinical and laboratory features of ACS and to assess the predisposing factors and predictors of severity. A retrospective case-control cohort was stu...

journal_title：Scientific reports

authors： Alkindi S,Al-Busaidi I,Al-Salami B,Raniga S,Pathare A,Ballas SK

更新日期：2020-02-12 00:00:00

abstract：:The study aimed to compare the tumor response to and complications of doxorubicin-eluting CalliSphere bead-transarterial chemoembolization (DEB-TACE) using small- and medium-sized beads in patients with hepatocellular carcinoma (HCC) who underwent multiple rounds of oncology therapies. Sixty patients with intermediate...

journal_title：Scientific reports

authors： Wang CY,Xia JG,Yang ZQ,Zhou WZ,Chen WH,Qi CJ,Gu JP,Wang Q

更新日期：2020-03-10 00:00:00

abstract：:Duchenne muscular dystrophy, one of the most common lethal genetic disorders, is caused by mutations in the DMD gene and a lack of dystrophin protein. In most DMD patients and animal models, sporadic dystrophin-positive muscle fibres, called revertant fibres (RFs), are observed in otherwise dystrophin-negative backgro...

journal_title：Scientific reports

authors： Rodrigues M,Echigoya Y,Maruyama R,Lim KR,Fukada SI,Yokota T

更新日期：2016-12-07 00:00:00

abstract：:The limits of mammography have led to an increasing interest on possible alternatives such as the breast Computed Tomography (bCT). The common goal of all X-ray imaging techniques is to achieve the optimal contrast resolution, measured through the Contrast to Noise Ratio (CNR), while minimizing the radiological risks,...

journal_title：Scientific reports

authors： Delogu P,Di Trapani V,Brombal L,Mettivier G,Taibi A,Oliva P

更新日期：2019-09-11 00:00:00

abstract：:Monitoring marine top predators is fundamental for assessing the health and functioning of open ocean ecosystems. Although recently tracking observations have substantially increased, factors determining the horizontal exploration of the ocean by marine predators are still largely unknown, especially at the scale of b...

journal_title：Scientific reports

authors： Della Penna A,De Monte S,Kestenare E,Guinet C,d'Ovidio F

更新日期：2015-12-15 00:00:00

abstract：:Functional DNA sub-sequences and genome elements are spatially clustered through the genome just as keywords in literary texts. Therefore, some of the methods for ranking words in texts can also be used to compare different DNA sub-sequences. In analogy with the literary texts, here we claim that the distribution of d...

journal_title：Scientific reports

authors： Moghaddasi H,Khalifeh K,Darooneh AH

更新日期：2017-01-27 00:00:00

abstract：:Deconvolution is widely used to improve the contrast and clarity of a 3D focal stack collected using a fluorescence microscope. But despite being extensively studied, deconvolution algorithms can introduce reconstruction artifacts when their underlying noise models or priors are violated, such as when imaging biologic...

journal_title：Scientific reports

authors： Ikoma H,Broxton M,Kudo T,Wetzstein G

更新日期：2018-07-31 00:00:00