Predictors of impending acute chest syndrome in patients with sickle cell anaemia.

abstract：:Dectin-1, a classical pattern-recognition receptor, was now identified as an important regulator in immune homeostasis and cancer immunity through its extensive ligands binding functions and subsequent cytokines production. The aim of this study was to assess the clinical significance of dectin-1 expression in 290 pat...

journal_title：Scientific reports

authors： Xia Y,Liu L,Bai Q,Wang J,Xi W,Qu Y,Xiong Y,Long Q,Xu J,Guo J

更新日期：2016-09-07 00:00:00

abstract：:Acanthamoeba can cause visually destructive Acanthamoeba keratitis (AK) in contact lens (CL) users. The purpose of this study was to determine whether Acanthamoeba was present in the CL cases of CL wearers and to develop techniques to prevent the contaminations. To accomplish this, 512 CL case samples were collected f...

journal_title：Scientific reports

authors： Miyazaki D,Eguchi H,Kuwahara T,Nakayama-Imaohji H,Inaba M,Itoi M,Ueda K,Ohashi Y,Sado K,Mizutani S,Miyamoto H,Sasaki SI,Shimizu Y,Inoue Y

更新日期：2020-07-28 00:00:00

abstract：:L-arginine:glycine amidinotransferase (AGAT) and its metabolites creatine and homoarginine (HA) have been linked to cardiovascular pathologies in both human and murine studies, but the underlying molecular mechanisms are poorly understood. Here, we report the first analysis of heart transcriptome variation using micro...

journal_title：Scientific reports

authors： Jensen M,Müller C,Choe CU,Schwedhelm E,Zeller T

更新日期：2020-03-16 00:00:00

abstract：:There is a growing need for low-cost, portable technologies for the detection of threats to the environment and human health. Here we propose a label-free, optical whole-cell Escherichia coli biosensor for the detection of 3-phenoxybenzoic acid (3-PBA), a biomarker for monitoring human exposure to synthetic pyrethroid...

journal_title：Scientific reports

authors： Riangrungroj P,Bever CS,Hammock BD,Polizzi KM

更新日期：2019-08-28 00:00:00

abstract：:Patients who undergo total hip arthroplasty (THA) may experience a large amount of blood loss. The objective of our study is to include randomized controlled trials (RCTs) and compare the clinical outcomes of fibrin sealant (FS) versus placebo after a THA. In October 2015, we searched the following databases: Medline,...

journal_title：Scientific reports

authors： Zhao Z,Ma X,Ma J,Sun X,Li F,Lv J

更新日期：2018-01-08 00:00:00

abstract：:There is lack of consensus regarding the prognostic significance of primary tumor location of upper tract urothelial carcinoma(UTUC). We performed a meta-analysis to evaluate the impact of primary tumor location on prognosis in patients with UTUC who had undergone radical nephroureterectomy(RNU). We included eligible ...

journal_title：Scientific reports

authors： Wu Y,Dong Q,Liu L,Han P,Wei Q

更新日期：2014-09-15 00:00:00

abstract：:Chromosomal toxin-antitoxin (TA) systems are widespread genetic elements among bacteria, yet, despite extensive studies in the last decade, their biological importance remains ambivalent. The ability of TA-encoded toxins to affect stress tolerance when overexpressed supports the hypothesis of TA systems being associat...

journal_title：Scientific reports

authors： Rosendahl S,Tamman H,Brauer A,Remm M,Hõrak R

更新日期：2020-06-08 00:00:00

abstract：:Psychopathic traits of conduct disorder (CD) have a core callous-unemotional (CU) component and an impulsive-antisocial component. Previous task-driven fMRI studies have suggested that psychopathic traits are associated with dysfunction of several brain areas involved in different cognitive functions (e.g., empathy, r...

journal_title：Scientific reports

authors： Pu W,Luo Q,Jiang Y,Gao Y,Ming Q,Yao S

更新日期：2017-09-12 00:00:00

abstract：:Coral reefs have been subject to mass coral bleaching, potentially causing rapid and widespread degradation of ecosystem services that depend on live coral cover, such as fisheries catch. Fisheries species in tropical waters associate with a wide range of habitats, so assessing the dependency of fisheries on coral ree...

journal_title：Scientific reports

authors： Brown CJ,Taylor W,Wabnitz CCC,Connolly RM

更新日期：2020-10-20 00:00:00

abstract：:Surgical treatment of tendon lesions still yields unsatisfactory clinical outcomes. The use of bioresorbable scaffolds represents a way forward to improve tissue repair. Scaffolds for tendon reconstruction should have a structure mimicking that of the natural tendon, while providing adequate mechanical strength and st...

journal_title：Scientific reports

authors： Sensini A,Gualandi C,Zucchelli A,Boyle LA,Kao AP,Reilly GC,Tozzi G,Cristofolini L,Focarete ML

更新日期：2018-11-21 00:00:00

abstract：:A novel ignition hohlraum for indirect-drive inertial confinement fusion is proposed, which is named three-axis cylindrical hohlraum (TACH). TACH is a kind of 6 laser entrance holes (LEHs) hohlraum, which is orthogonally jointed of three cylindrical hohlraums. Laser beams are injected through every entrance hole with ...

journal_title：Scientific reports

authors： Kuang L,Li H,Jing L,Lin Z,Zhang L,Li L,Ding Y,Jiang S,Liu J,Zheng J

更新日期：2016-10-05 00:00:00

abstract：:This study analyzed hourly mass concentration observations of PM2.5 (particulate matters with diameter less than 2.5 μm) at 512 stations in China from December 2013 to May 2015. We found that the mean concentrations of PM2.5 during the winter and spring of 2015 Dec. 2014 to Feb. 2015 and Mar. 2015 to May 2015) decreas...

journal_title：Scientific reports

authors： Wang X,Wang K,Su L

更新日期：2016-11-02 00:00:00

abstract：:In eye movement perimetry (EMP), the saccadic reaction time (SRT) to 'seen' visual stimuli are delayed in glaucoma. Evaluating SRT behaviour in hemi-field sectors could refine its clinical implication. The development phase included 60 controls retrospectively and for the test cohort in evaluation phase, another 30 he...

journal_title：Scientific reports

authors： Mazumdar D,Meethal NSK,George R,Pel JJM

更新日期：2021-01-29 00:00:00

abstract：:Protocadherin 19 (Pcdh19) is an X-linked gene belonging to the protocadherin superfamily, whose members are predominantly expressed in the central nervous system and have been implicated in cell-cell adhesion, axon guidance and dendrite self-avoidance. Heterozygous loss-of-function mutations in humans result in the ch...

journal_title：Scientific reports

authors： Pederick DT,Homan CC,Jaehne EJ,Piltz SG,Haines BP,Baune BT,Jolly LA,Hughes JN,Gecz J,Thomas PQ

更新日期：2016-05-31 00:00:00

abstract：:Cancer immunotherapy, including immune checkpoint inhibitors, exerts beneficial effects in cancer patients. However, immune checkpoint inhibitors are only advantageous for a limited population of cancer patients. Therefore, companion diagnostics are needed in order to identify patients for whom these therapies are eff...

journal_title：Scientific reports

authors： Iwahori K,Shintani Y,Funaki S,Yamamoto Y,Matsumoto M,Yoshida T,Morimoto-Okazawa A,Kawashima A,Sato E,Gottschalk S,Okumura M,Kumanogoh A,Wada H

更新日期：2019-02-22 00:00:00

abstract：:In situ reduction of selenite to elemental selenium (Se(0)), by microorganisms in sediments and soils is an important process and greatly affects the environmental distribution and the biological effects of selenium. However, the mechanism behind such a biological process remains unrevealed yet. Here we use Shewanella...

journal_title：Scientific reports

authors： Li DB,Cheng YY,Wu C,Li WW,Li N,Yang ZC,Tong ZH,Yu HQ

更新日期：2014-01-17 00:00:00

abstract：:We demonstrate that laser peening coupled with sintering of CdTe nanowire films substantially enhances film quality and charge transfer while largely maintaining basic particle morphology. During the laser peening phase, a shockwave is used to compress the film. Laser sintering comprises the second step, where a nanos...

journal_title：Scientific reports

authors： Rickey KM,Nian Q,Zhang G,Chen L,Suslov S,Bhat SV,Wu Y,Cheng GJ,Ruan X

更新日期：2015-11-03 00:00:00

abstract：:Ecosystem carbon carrying capacity (CCC) is determined by prevailing climate and natural disturbance regimes, conditions that are projected to change significantly. The interaction of changing climate and its effects on disturbance regimes is expected to affect forest regeneration and growth, which may diminish forest...

journal_title：Scientific reports

authors： Liang S,Hurteau MD,Westerling AL

更新日期：2017-05-25 00:00:00

abstract：:Enterococci are nosocomial pathogens that can form biofilms, which contribute to their virulence and antibiotic resistance. Although many genes involved in biofilm formation have been defined, their distribution among enterococci has not been comprehensively studied on a genome scale, and their diagnostic ability to p...

journal_title：Scientific reports

authors： Hashem YA,Amin HM,Essam TM,Yassin AS,Aziz RK

更新日期：2017-07-18 00:00:00

abstract：:Salvia miltiorrhiza is one of the most widely-used medicinal plants. Here, we systematically analyzed the RNA editing events in its mitochondria. We developed a pipeline using REDItools to predict RNA editing events from stand-specific RNA-Seq data. The predictions were validated using reverse transcription, RT-PCR am...

journal_title：Scientific reports

authors： Wu B,Chen H,Shao J,Zhang H,Wu K,Liu C

更新日期：2017-02-10 00:00:00

abstract：:Microinjection is commonly performed to achieve fish transgenesis; however, due to difficulties associated with this technique, new strategies are being developed. Here we evaluate the potential of lentiviral particles to genetically modify Nile tilapia cells to achieve transgenesis using three different approaches: s...

journal_title：Scientific reports

authors： Tonelli FM,Lacerda SM,Procópio MS,Lemos BL,de França LR,Resende RR

更新日期：2017-03-20 00:00:00

abstract：:Neurodegenerative diseases show an increase in prevalence and incidence, with the most prominent example being Alzheimer's disease. DNA damage has been suggested to play a role in the pathogenesis, but the exact mechanisms remain elusive. We enrolled 425 participants with and without neurodegenerative diseases and ana...

journal_title：Scientific reports

authors： Reimann H,Stopper H,Polak T,Lauer M,Herrmann MJ,Deckert J,Hintzsche H

更新日期：2020-12-17 00:00:00

abstract：:The concept of parity-time (PT) symmetry in SPPs is proposed and confirmed for the first time in this work. By introducing periodic modulation of the effective refractive index in SPP system, the asymmetric propagation is theoretically predicted and numerically demonstrated. After validation of this concept, we apply ...

journal_title：Scientific reports

authors： Yang F,Lei Mei Z

更新日期：2015-10-08 00:00:00

abstract：:To investigate the safety, cost-effectiveness, and clinical outcomes of simultaneous bilateral total knee arthroplasty (TKA) in hemophilic arthropathy (HA), the requirements for transfusions, complications, costs, hospital stays, Hospital for Special Surgery (HSS) knee scores, knee range of motion (ROM) and revision r...

journal_title：Scientific reports

authors： Jiang C,Zhao Y,Feng B,Zhai J,Bian Y,Qiu G,Weng X

更新日期：2018-01-25 00:00:00

abstract：:Buccal mucosa squamous cell carcinoma (BMSCC) is one of major subsites of oral cancer and is associated with a high rate of metastasis and poor prognosis. Heat shock proteins (HSPs) act as potential prognostic biomarkers in many cancer types. However, the role of HSPD1 in oral cancer, especially in BMSCC, is still unk...

journal_title：Scientific reports

authors： Kang BH,Shu CW,Chao JK,Lee CH,Fu TY,Liou HH,Ger LP,Liu PF

更新日期：2019-06-20 00:00:00

abstract：:Sex hormones fluctuate during the menstrual cycle. Evidence from animal studies suggests similar subtle fluctuations in hippocampal structure, predominantly linked to estrogen. Hippocampal abnormalities have been observed in several neuropsychiatric pathologies with prominent sexual dimorphism. Yet, the potential impa...

journal_title：Scientific reports

authors： Barth C,Steele CJ,Mueller K,Rekkas VP,Arélin K,Pampel A,Burmann I,Kratzsch J,Villringer A,Sacher J

更新日期：2016-10-07 00:00:00

abstract：:The biochemical abnormalities and oxidative stress during pathogenesis of hepatic fibrosis could lead to alteration of trace elements. We studied the alteration of major trace elements during the pathogenesis of N-nitrosodimethylamine (NDMA)-induced hepatic fibrosis in rats. The biochemical and pathological indices of...

journal_title：Scientific reports

authors： George J,Tsutsumi M,Tsuchishima M

更新日期：2019-01-24 00:00:00

abstract：:Seeing with two eyes usually helps one respond faster. Here we show that with ambiguous stimuli, binocular viewing can paradoxically slow down reaction time. This is explained by the observers basing their decision on a noisy neuronal representation within the visual system, with the added noise breaking the symmetry ...

journal_title：Scientific reports

authors： Yehezkel O,Sterkin A,Sagi D,Polat U

更新日期：2015-11-18 00:00:00

abstract：:The most common surgical emergency is suspected acute appendicitis, the lifetime risk of acute appendicitis is estimated to be 8.6% for men and 6.7% for women, with a male to female ratio of 1.4:1; correct diagnosis can be made in 70-80% of patients after the operations about 32% of appendectomies revealed normal appe...

journal_title：Scientific reports

authors： Ahmed HO,Muhedin R,Boujan A,Aziz AHS,Abdulla AM,Hardi RA,Abdulla AA,Sidiq TA

更新日期：2020-02-06 00:00:00

abstract：:Efforts for tissue engineering vascular grafts focuses on the tunica media and intima, although the tunica adventitia serves as the primary structural support for blood vessels. In surgery, during endarterectomies, surgeons can strip the vessel, leaving the adventitia as the main strength layer to close the vessel. He...

journal_title：Scientific reports

authors： Patel B,Xu Z,Pinnock CB,Kabbani LS,Lam MT

更新日期：2018-02-19 00:00:00