5-Hydroxytryptamine 1A and 2B serotonin receptors in neurite outgrowth: involvement of early growth response protein 1.

abstract：:Our previous studies of H218, a sphingosine 1-phosphate (S1P) receptor and a member of the G-protein-coupled receptor superfamily, suggest that it may participate in mammalian nervous system development. Thus, brain levels of H218 mRNA are higher during early neurogenesis than postnatally. In addition, embryonic H218 ...

journal_title：Developmental neuroscience

authors： MacLennan AJ,Devlin BK,Marks L,Gaskin AA,Neitzel KL,Lee N

更新日期：2000-01-01 00:00:00

abstract：:Dissociated cells from chick embryo encephalon of 36 h of incubation have been cultivated on fibroblast, meningeal cell, or glial layers. Within the first 24 h of cultivation, cells adhered to the preformed layers more firmly than to plastic or collagen surfaces. After 48 h of cultivation, the brain cells cultured on ...

journal_title：Developmental neuroscience

authors： Touzet N,Sensenbrenner M

更新日期：1978-01-01 00:00:00

abstract：:Three experimental approaches were used to examine the maturation of N-methyl-D-aspartate (NMDA) receptors in the neostriatum and compare their developmental profile to that of the non-NMDA receptors [alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and kainate (KA)]. The first, and least conventional ...

journal_title：Developmental neuroscience

authors： Colwell CS,Cepeda C,Crawford C,Levine MS

更新日期：1998-01-01 00:00:00

abstract：:Parallel developmental studies of central nervous system myelin proteins and morphology (postnatal days 15-118; P15-118) confirm qualitative similarities but substantial quantitative differences between homozygous mld mice with Billings-Gagliardi and Wolf's 'USA' versus Matthieu's 'Swiss' genetic backgrounds. The USA ...

journal_title：Developmental neuroscience

authors： Billings-Gagliardi S,Tosic M,Matthieu JM,Kirschner DA,Wolf MK

更新日期：1991-01-01 00:00:00

abstract：:The kinetics and sodium-dependence of gamma-aminobutyric acid (GABA), hypotaurine and taurine uptake were analyzed in cerebral slices prepared from mice of different postnatal ages. The maximal velocities of transport (V) and the Km constants for the high-affinity uptake all decreased with age, whereas the development...

journal_title：Developmental neuroscience

authors： Oja SS,Kontro P

更新日期：1983-01-01 00:00:00

abstract：:We have shown that the developmentally regulated appearance of the two myelin-associated glycoprotein (MAG) polypeptides in normal mouse brain myelin does not reflect the developmental pattern of differential splicing of primary gene transcripts as determined earlier by RNase protection assays. Contrary to expectation...

journal_title：Developmental neuroscience

authors： Braun PE,Horvàth E,Edwards AM

更新日期：1990-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) is predominantly a clinical problem of young persons, resulting in chronic cognitive and behavioral deficits. Specifically, the physiological response to a diffuse biomechanical injury in a maturing brain can clearly alter normal neuroplasticity. To properly evaluate and investigate develo...

journal_title：Developmental neuroscience

authors： Giza CC,Prins ML

更新日期：2006-01-01 00:00:00

abstract：:Primary cultures of cerebellum from 5-day-old rats indicated that proliferating neuroblasts synthesize and release nerve growth factor (NGF). Since NGF promotes DNA synthesis in these cells, our findings demonstrate that the early developing cerebellum is a suitable physiological model for studying the autocrine mitog...

journal_title：Developmental neuroscience

authors： Charrasse S,Jehan F,Confort C,Brachet P,Clos J

更新日期：1992-01-01 00:00:00

abstract：:Quaking is a neurological mutation leading to pleiotropic phenotypic expression, the most prominent being disturbed myelin formation in the central nervous system (CNS) with minor abnormalities in the peripheral nervous system. Previous immunochemical measurements of glial fibrillary acidic protein (GFAP) revealed a m...

journal_title：Developmental neuroscience

authors： Chen H,Sun P,Parmantier E,Cabon F,Dupouey P,Zalc B,Jacque C

更新日期：1992-01-01 00:00:00

abstract：:Cell polarity is one of the most basic properties of all normal cells and loss of polarity is a hallmark of cancer. While multiple proteins have been implicated in the maintenance of cell polarity, the functionally related neoplastic tumor suppressors Lethal giant larvae (Lgl), Scribble and Disks large comprise a uniq...

journal_title：Developmental neuroscience

authors： Vasioukhin V

更新日期：2006-01-01 00:00:00

abstract：:The hippocampal formation is a multicomponent region of the medial temporal lobe preferentially involved in declarative and relational memory processing. Behavioral studies have suggested a protracted functional maturation of these structures in primates, and postnatal developmental abnormalities in the hippocampal fo...

journal_title：Developmental neuroscience

authors： Lavenex P,Banta Lavenex P,Amaral DG

更新日期：2007-01-01 00:00:00

abstract：:Nitric oxide (NO) is a recently recognized messenger molecule that has been shown to possess pleiotropic properties, including vasodilation, neurotransmission, cytotoxicity and antimicrobial activity. Constitutive and inducible forms of NO synthase (NOS) have been identified. Activation of cNOS releases relatively low...

journal_title：Developmental neuroscience

authors： Brosnan CF,Battistini L,Raine CS,Dickson DW,Casadevall A,Lee SC

更新日期：1994-01-01 00:00:00

abstract：:The Notch signaling pathway is important at several stages of retinal development including the differentiation of retinal ganglion cells and Muller glia. The downstream effectors of Notch signaling, Hes1 and Hes5, have been shown to be critical in the retina as well. While Notch activity directly regulates Hes1 and H...

journal_title：Developmental neuroscience

authors： Nelson BR,Gumuscu B,Hartman BH,Reh TA

更新日期：2006-01-01 00:00:00

abstract：:Developmental expression of neutral monoglycosylceramides (MGCs) has been examined in rat brain from embryonic day 15 (E15) to postnatal day 30 (P30) and adulthood. To this point, glucosylceramide (GlcCer) is the only MGC that has been characterized in embryonic brain. Galactosylceramide (GalCer) appears at P1, increa...

journal_title：Developmental neuroscience

authors： Dasgupta S,Everhart MB,Bhat NR,Hogan EL

更新日期：1997-01-01 00:00:00

abstract：:Rats were exposed to mild hyperoxia and hypoxia by the administration of oxygen/air and nitrogen/air mixtures through plastic tubing held close to their snouts for periods of 3 min. Changes in tissue oxygen were monitored at an implanted carbon paste electrode; local cerebral blood flow (rCBF) at an implanted platinum...

journal_title：Developmental neuroscience

authors： Lowry JP,Demestre M,Fillenz M

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Neonatal hypoxic-ischemic (HI) encephalopathy occurs in 1-4 per 1,000 live term births and can cause devastating neurodevelopmental disabilities. Currently, therapeutic hypothermia (TH) is the only treatment with proven efficacy. Since TH is associated with decreased cerebral metabolism and cerebral blood fl...

journal_title：Developmental neuroscience

authors： Buckley EM,Patel SD,Miller BF,Franceschini MA,Vannucci SJ

更新日期：2015-01-01 00:00:00

abstract：:Early developmental treatment of rats with 3,4-methylenedioxymethamphetamine (MDMA) was previously found to cause an abnormal pattern of forebrain serotonergic axon density in adulthood consisting of a cortical hypoinnervation and a striatal hyperinnervation. The present study tested the hypothesis that this reorganiz...

journal_title：Developmental neuroscience

authors： Piper BJ,Farelli JD,Meyer JS

更新日期：2009-01-01 00:00:00

abstract：:We studied the developmental changes of soluble and membrane-bound protein kinases (EC 2.7.1.37) in rat brain and found that the elution profiles from a DEAE-cellulose column by NaCl of adenosine-3':5'-monophosphate (cyclic AMP) dependent protein kinase from cytosol were not significantly different in newborn (0.19 M ...

journal_title：Developmental neuroscience

authors： Kinnier WJ,Chikvaidze V,Hollenbeck RA,Chuang DM,Costa E

更新日期：1979-01-01 00:00:00

abstract：:Transient early cerebral laminar organization resulting from normal developmental events has been revealed in human beings through histology and imaging studies. DTI studies have postulated that the fractional anisotropy (FA)-based differentiation of different laminar structures reflects both differing cellular densit...

journal_title：Developmental neuroscience

authors： Trivedi R,Husain N,Rathore RK,Saksena S,Srivastava S,Malik GK,Das V,Pradhan M,Pandey CM,Gupta RK

更新日期：2009-01-01 00:00:00

abstract：:Early developmental processes, such as metabolic programming, can provide cues to an organism, which allow it to make modifications that are predicted to be beneficial for survival. Similarly, social play has a multifaceted role in promoting survival and fitness of animals. Play is a complex behavior that is greatly i...

journal_title：Developmental neuroscience

authors： Hehar H,Ma I,Mychasiuk R

更新日期：2016-01-01 00:00:00

abstract：:The lipids of white matter and peripheral nerve from mutant mice with known myelin deficiencies were analyzed by one- and two-dimensional high-performance thin-layer chromatography and quantitated by densitometry. In optic nerve, the mutants jp/Y, jpmsd/Y, qk/qk, shi/shi and shimld/shimld, which have severe central ne...

journal_title：Developmental neuroscience

authors： Ganser AL,Kerner AL,Brown BJ,Davisson MT,Kirschner DA

更新日期：1988-01-01 00:00:00

abstract：:It has been demonstrated that postweaning social isolation alters dendritic development in the medial prefrontal cortex (mPFC) of the rat. In addition, (-)-deprenyl, a monoamine oxidase B (MAO-B) inhibitor, promotes dendritic growth in prefrontocortical pyramidal cells. This study examined whether prefrontocortical de...

journal_title：Developmental neuroscience

authors： Pascual R,Zamora-León SP

更新日期：2007-01-01 00:00:00

abstract：:The spontaneously immortalized S16 Schwann cell line expresses higher levels of myelin-associated glycoprotein (MAG) and PO glycoprotein and their messenger RNAs when grown at high density than at low density [Sasagasako et al: J Neurochem 1996;66:1432-1439]. This up-regulation of myelin protein expression at high den...

journal_title：Developmental neuroscience

authors： Sasagasako N,Ohno M,Quarles RH

更新日期：1999-01-01 00:00:00

abstract：:Fragile X syndrome (FXS) is a neurodevelopmental disorder characterized by intellectual disability, sensory hypersensitivity, and high incidences of autism spectrum disorders and epilepsy. These phenotypes are suggestive of defects in neural circuit development and imbalances in excitatory glutamatergic and inhibitory...

journal_title：Developmental neuroscience

authors： Paluszkiewicz SM,Martin BS,Huntsman MM

更新日期：2011-01-01 00:00:00

abstract：:Various abnormalities in frontal and striatal regions have been reported in children with prenatal alcohol and/or methamphetamine exposure. In a recent fMRI study, we observed a correlation between accuracy on a working-memory task and functional activation in the putamen in children with prenatal methamphetamine and ...

journal_title：Developmental neuroscience

authors： Roussotte FF,Rudie JD,Smith L,O'Connor MJ,Bookheimer SY,Narr KL,Sowell ER

更新日期：2012-01-01 00:00:00

abstract：:The myelin-associated glycoprotein (MAG) is a 100 K-dalton, integral membrane glycoprotein containing 30% carbohydrate that is in central and peripheral myelin sheaths. Recent research on its function during normal myelinogenesis and possible roles in the pathology of demyelinating diseases is reviewed. Emphasis is pl...

journal_title：Developmental neuroscience

authors： Quarles RH

更新日期：1983-01-01 00:00:00

abstract：:Myelinogenesis in different brain parts of trout was studied comparatively by means of histochemistry and biochemistry. A more detailed approach, including ultrastructural analysis, to characterize this important differentiation process, particularly in the optic tectum, revealed a good correlation between the structu...

journal_title：Developmental neuroscience

authors： Jeserich G

更新日期：1981-01-01 00:00:00

abstract：:The postnatal development of the complexes of the electron transport chain in mitochondria isolated from rat brain synaptosomes was investigated. Synaptosomal brain mitochondria were isolated from rats aged 10-60 days, and the activities of mitochondrial complex I, complex II-III, complex IV and complex V were measure...

journal_title：Developmental neuroscience

authors： Almeida A,Brooks KJ,Sammut I,Keelan J,Davey GP,Clark JB,Bates TE

更新日期：1995-01-01 00:00:00

abstract：:Previous studies have demonstrated that exposure to ethanol during development delays the rate at which axons in certain central nervous system tracts acquire myelin. This delay appears to be related to an alteration in oligodendrocyte function and not to an aberrancy in axon size or number. The present study was desi...

journal_title：Developmental neuroscience

authors： McNeill DL,Shew RL,Papka RE

更新日期：1991-01-01 00:00:00

abstract：:The developing retina is characterized by 'retinal waves', spontaneous depolarizations that propagate through a developing network of interneurons and retinal ganglion cells. Although the circuitry underlying retinal waves is well characterized, the secreted factors that are critical for its normal development are not...

journal_title：Developmental neuroscience

authors： Colicos MA,Firth SI,Bosze J,Goldstein J,Feller MB

更新日期：2004-01-01 00:00:00