Comparison of four methods for assessment of severity of hand eczema.

Abstract:

BACKGROUND:Several instruments for the assessment of the severity of hand eczema and health-related quality of life (HR-QoL) related to hand eczema have been developed. OBJECTIVES:The aim of the present study was to evaluate the correlation between frequently used methods. METHODS:Consecutive patients with current hand eczema from three different centres participated in the study. Severity of hand eczema was assessed with the Hand Eczema Severity Index (HECSI), the Physician Global Assessment (PGA), the Clinical Photo Guide, and the Dermatology Life Quality Index (DLQI). RESULTS:One hundred and nineteen patients with hand eczema were included in the study. All six pairwise correlation coefficients between the tested methods were highly statistically significant. Correlation was highest between the HECSI and the PGA (r = 0.82), and weakest, although still statistically significant, between the DLQI and the other three severity scores (r between 0.30 and 0.45). Age and frequency of eruptions did not influence the correlations. With respect to sex, there was a tendency for correlation between methods to be higher for men than for women. CONCLUSION:We found an overall positive correlation between the four severity assessments applied. As the weakest correlation was found between the DLQI and the other methods, it is suggested that measurement of HR-QoL should be included for assessment of the severity and consequences of hand eczema, but the finding also indicates that a disease-specific tool for evaluation of HR-QoL in hand eczema patients is needed.

journal_name

Contact Dermatitis

journal_title

Contact dermatitis

authors

Agner T,Jungersted JM,Coenraads PJ,Diepgen T

doi

10.1111/cod.12039

subject

Has Abstract

pub_date

2013-08-01 00:00:00

pages

107-11

issue

2

eissn

0105-1873

issn

1600-0536

journal_volume

69

pub_type

杂志文章
  • Contact sensitization in Dutch children and adolescents with and without atopic dermatitis - a retrospective analysis.

    abstract:BACKGROUND:Allergic contact dermatitis is known to occur in children with and without atopic dermatitis, but more data are needed on contact sensitization profiles in these two groups. OBJECTIVES:To identify frequent allergens in children with and without atopic dermatitis suspected of having allergic contact dermatit...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12711

    authors: Lubbes S,Rustemeyer T,Sillevis Smitt JH,Schuttelaar ML,Middelkamp-Hup MA

    更新日期:2017-03-01 00:00:00

  • Subacute parathion poisoning with erysipeloid-like lesion.

    abstract::A case of subacute parathion poisoning with an erysipeloid-like eruption of the left index finger is reported. Laboratory investigations showed no growth of pathogenic bacteria and cholinesterase activity in the blood showed a rise 10 days after the poisoning. Further blood investigations 6 weeks later showed subnorma...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1981.tb04037.x

    authors: Svindland HB

    更新日期:1981-07-01 00:00:00

  • Multicentre patch testing with a resol resin based on phenol and formaldehyde.

    abstract:BACKGROUND:Contact allergy to phenol-formaldehyde resins (PFRs) based on phenol and formaldehyde is not detected by a p-tertiary-butylphenol-formaldehyde resin (PTBP-FR) included in most baseline patch test series. OBJECTIVES:To investigate the rate of contact allergy to PFR-2 (a mixture of monomers and dimers from a ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1600-0536.2011.01921.x

    authors: Isaksson M,Inerot A,Lidén C,Matura M,Stenberg B,Möller H,Bruze M

    更新日期:2011-07-01 00:00:00

  • A simple method of qualitative analysis for musk ambrette, musk ketone and musk xylene in cologne.

    abstract::Musk ambrette has become one of the commonest photosensitizers in many countries and is the cause of persistent light reactions in many patients. A simple method is presented for qualitative analysis for musk ambrette and other nitromusks in colognes using thin-layer chromatography with toluene as carrier solvent and ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1986.tb01153.x

    authors: Goh CL,Kwok SF

    更新日期:1986-01-01 00:00:00

  • Skin condition associated with intensive use of alcoholic gels for hand disinfection: a combination of biophysical and sensorial data.

    abstract::Although hand hygiene is an important and inexpensive measure to prevent nosocomial infections in clinical settings, the compliance of healthcare workers remains low. In Europe, alcoholic hand disinfection is first choice, but there exists a limited user acceptability due to estimated adverse effects on skin condition...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.0105-1873.2006.00817.x

    authors: Houben E,De Paepe K,Rogiers V

    更新日期:2006-05-01 00:00:00

  • The role of contact allergy to aeroallergens in atopic dermatitis.

    abstract::In some patients with atopic dermatitis (AD), delayed-type allergy to aeroallergens, such as house dust mite, can be demonstrated by patch testing. Positive patch tests can be expected only in patients with AD and, in them, only to aeroallergens to which type 1 reactions have also been demonstrated. In an as yet unkno...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0536.1989.tb03197.x

    authors: de Groot AC,Young E

    更新日期:1989-10-01 00:00:00

  • Chromium in leather footwear - risk assessment of chromium allergy and dermatitis.

    abstract:BACKGROUND:Chromium-tanned leather footwear, which releases >3 ppm hexavalent Cr(VI), may pose a risk of sensitizing and eliciting allergic dermatitis. OBJECTIVES:To determine the content and potential release of chromium in leather footwear and to discuss the prevention of chromium contact allergy and dermatitis. ME...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2011.02053.x

    authors: Thyssen JP,Strandesen M,Poulsen PB,Menné T,Johansen JD

    更新日期:2012-05-01 00:00:00

  • Fragrances and other materials in deodorants: search for potentially sensitizing molecules using combined GC-MS and structure activity relationship (SAR) analysis.

    abstract::Deodorants are one of the most frequently-used types of cosmetics and are a source of allergic contact dermatitis. Therefore, a gas chromatography - mass spectrometric analysis of 71 deodorants was performed for identification of fragrance and non-fragrance materials present in marketed deodorants. Futhermore, the sen...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1998.tb05944.x

    authors: Rastogi SC,Lepoittevin JP,Johansen JD,Frosch PJ,Menné T,Bruze M,Dreier B,Andersen KE,White IR

    更新日期:1998-12-01 00:00:00

  • A patch test closet.

    abstract::A way of adapting a treatment room for patch test purposes is described. ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1975.tb05362.x

    authors: Epstein E

    更新日期:1975-06-01 00:00:00

  • Are gloves sufficiently protective when hairdressers are exposed to permanent hair dyes? An in vivo study.

    abstract:BACKGROUND:The use of permanent hair dyes exposes hairdressers to contact allergens such as p-phenylenediamine (PPD), and the preventive measures are insufficient. OBJECTIVES:To perform an in vivo test to study the protective effect of gloves commonly used by hairdressers. PATIENTS/MATERIALS/METHODS:Six gloves from S...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12320

    authors: Antelmi A,Young E,Svedman C,Zimerson E,Engfeldt M,Foti C,Bruze M

    更新日期:2015-04-01 00:00:00

  • Positive nickel patch tests do not intensify positive reactions to adjacent patch tests with dichromate. Results from a double-blind multicentre study of the German Contact Dermatitis Research Group (Deutsche Kontaktallergie-Gruppe, DKG).

    abstract::The possible interference of neighbouring allergic patch-test reactions is still an open question. In this study, we investigated whether there is a distance-related mutual modification of neighbouring allergic patch-test reactions to nickel sulfate and potassium dichromate. We used a double-blind multicentre study de...

    journal_title:Contact dermatitis

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1034/j.1600-0536.2000.043003144.x

    authors: Brasch J,Kreilgård B,Henseler T,Aberer W,Fuchs T,Pflüger R,Hoeck U,Gefeller O

    更新日期:2000-09-01 00:00:00

  • Addressing the conundrums of p-phenylenediamine hair dye allergy by applying Friedmann's principles of contact sensitization.

    abstract::In the first conundrum, permanent hair dyeing involves the use of aromatic amines such as p-phenylenediamine (PPD), whose oxidation is pivotal to the dyeing process, but also generates potent allergens. Despite prolonged efforts by industry to search for safer alternatives, hair dyeing is still reliant on this type of...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13171

    authors: Ferguson FJ,Pongpairoj K,Basketter DA,White IR,McFadden JP

    更新日期:2019-04-01 00:00:00

  • Contact Allergy to Polyhexamethylene Biguanide (Polyaminopropyl Biguanide).

    abstract:BACKGROUND:Polyaminopropyl biguanide (INCI name) and polyhexamethylene biguanide (PHMB) are polymeric biguanides. PHMB is a broad-spectrum antimicrobial substance used as a preservative in many products. Due to our limited knowledge on PHMB contact allergy frequency and the fact that cases of allergic contact dermatiti...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13728

    authors: Sukakul T,Dahlin J,Pontén A,Antelmi A,Bruze M,Hamnerius N,Hauksson I,Isaksson M,Lejding T,Svedman C

    更新日期:2020-10-24 00:00:00

  • Contact allergy due to colophony (VI). The sensitizing capacity of minor resin acids and 7 commercial modified-colophony products.

    abstract::3 minor resin acids and 7 commercial modified-colophony products of different origins were studied by experimental sensitization by means of a modified FCA method. All 3 resin acids were almost negative. The commercial products gave different results. While the maleic-modified product of Greek origin showed a strong s...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1990.tb03229.x

    authors: Hausen BM,Hessling C

    更新日期:1990-08-01 00:00:00

  • Nickel dermatitis from cheap earrings.

    abstract::In 1988, 64% of our patients patch test positive to at least 1 allergen of the ICDRG standard series were nickel sensitive. In 70% of 300 patients evaluated, dermatitis started on the earlobes and was related to the regular wearing of cheap earrings. At the same time, 62% of 735 young schoolgirls were found to have de...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1989.tb03203.x

    authors: Santucci B,Ferrari PV,Cristaudo A,Cannistraci C,Picardo M

    更新日期:1989-10-01 00:00:00

  • Down-regulation of protein kinase C isoforms in irritant contact dermatitis.

    abstract::Protein kinase C (PKC) isoforms are important in cell signal transduction associated with regulation of cell proliferation and differentiation. In this study, alterations of PKC isoform levels in irritant patch test reactions were detected by Western immunoblots. 4 chemically and structurally different irritants, 4% a...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1998.tb05766.x

    authors: Li LF,Fiedler VC,Kumar R

    更新日期:1998-06-01 00:00:00

  • Polyvinyl chloride work boots in the management of shoe dermatitis in industrial workers.

    abstract::A sugar refinery worker developed allergic contact dermatitis of his feet secondary to rubber accelerators in his work boots. The dermatitis resolved when polyvinyl chloride work boots were substituted. The importance of controlling hyperhidrosis in the management of foot dermatitis in workers is discussed. ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1979.tb04860.x

    authors: Mathias CG,Maibach HI

    更新日期:1979-07-01 00:00:00

  • Multispectral imaging of hand eczema.

    abstract:BACKGROUND:Hand eczema is a disease with large variation in clinical presentation and severity. Scoring systems for quantitative severity assessment exist. However, they are observer-dependent. An objective quantitative tool for scoring of hand eczema would improve categorization of hand eczema. OBJECTIVE:To investiga...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13377

    authors: Hald M,Thyssen JP,Zachariae C,Røpke MA,Carstensen JM,Schultz N,Johansen JD

    更新日期:2019-12-01 00:00:00

  • Experimental skin deposition of chromium on the hands following handling of samples of leather and metal.

    abstract:BACKGROUND:Chromium is an important skin sensitizer. Exposure to it has been regulated in cement, and recently in leather. Studies on the deposition of chromium ions on the skin as a result of handling different chromium-containing materials are sparse, but could improve the risk assessment of contact sensitization and...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12605

    authors: Bregnbak D,Thyssen JP,Jellesen MS,Zachariae C,Johansen JD

    更新日期:2016-08-01 00:00:00

  • A glove with exceptional protective features minimizes the risks of working with hazardous chemicals.

    abstract::In continuation of our preceding studies, we disclose long-term experiments to test more extensively the protective power of the novel 4H Glove. 2 compounds encountered in modern electron microscopy technique, 1-hexadecene (1-HD) and 2-hydroxyethyl acrylate (2-HEA), which elicit allergic and/or toxic reactions in labo...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1992.tb00122.x

    authors: Tobler M,Freiburghaus AU

    更新日期:1992-05-01 00:00:00

  • Oral challenge with metal salts. (I). Vesicular patch-test-negative hand eczema.

    abstract::202 patients, 68 males and 134 females, with patch-test-negative, symmetrical vesicular hand eczema were challenged orally in a controlled study with 2.5 mg nickel, 2.5 mg chromium and 1 mg cobalt given as salts of the respective metals. Initially a mixture of the 3 metal salts was given, and if this produced a flare ...

    journal_title:Contact dermatitis

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-0536.1983.tb04437.x

    authors: Veien NK,Hattel T,Justesen O,Nørholm A

    更新日期:1983-09-01 00:00:00

  • Percutaneous absorption of 3 organic solvents in the guinea pig (V). Effect of "accelerants".

    abstract::The influence of "accelerants" on the percutaneous absorption of 3 organic solvents (butanol, toluene, 1,1,1-trichloroethane) was investigated in the guinea pig. DMSO in binary and ternary mixtures with various concentrations, the result of adding 0.1 M C18 fatty acids, and of pretreatment with DMSO and olive oil, wer...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1989.tb04748.x

    authors: Boman A

    更新日期:1989-11-01 00:00:00

  • Occupational dermatosis among sanders in the furniture industry.

    abstract::The prevalence of occupational skin disease was found to be 3.8% in a study of 479 sanders in the furniture-making industry in Singapore. 17 species of wood imported from South East Asia were used. The most common dermatoses from wood dust were pruritus (1.6%), irritant contact dermatitis (1.6%) and xerosis (1.4%). 2 ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1987.tb02720.x

    authors: Gan SL,Goh CL,Lee CS,Hui KH

    更新日期:1987-10-01 00:00:00

  • Hand eczema in a prospectively-followed cohort of office-workers.

    abstract::A cohort of initially 111 office apprentices was prospectively followed for the duration of their training (2 and 3 years, respectively). The point prevalence of (slight) irritant or atopic hand eczema was 18.9% in the initial and 25.0% in the final examinations. Altogether, 37 cases of (slight) hand eczema were noted...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:

    authors: Uter W,Pfahlberg A,Gefeller O,Schwanitz HJ

    更新日期:1998-02-01 00:00:00

  • Contamination by nickel, copper and zinc during the handling of euro coins.

    abstract::The introduction of the euro has revived interest in the risk of nickel allergy due to the handling of coins. In the present work, the transfer of metallic contamination during the manipulation of coins is examined by means of leaching experiments and manipulation tests. It is shown that pre-existing metallic species ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1034/j.1600-0536.2003.00028.x

    authors: Fournier PG,Govers TR

    更新日期:2003-04-01 00:00:00

  • Contact dermatitis to ethyl-cyanoacrylate-containing glue.

    abstract::3 patients with contact dermatitis to an ethyl cyanoacrylate glue are presented. Although reactions to cyanoacrylate glues are considered rare, more widespread use of these products by nail salons is likely to be associated with an increased incidence of positive reactions. All 3 of our patients came into contact with...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1987.tb02719.x

    authors: Belsito DV

    更新日期:1987-10-01 00:00:00

  • Allergic contact dermatitis from 2-n-octyl-4-isothiazolin-3-one, a paint mildewcide.

    abstract::Severe allergic contact dermatitis from a paint mildewcide, 2-n-octyl-4-isothiazolin-3-one, developed in a worker formulating latex paints within a paint manufacturing company, Guinea pig maximization testing demonstrated this to be a moderate sensitizer. Further cases of allergic contact dermatitis may be encountered...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1983.tb04473.x

    authors: Mathias CG,Andersen KE,Hamann K

    更新日期:1983-11-01 00:00:00

  • Scarified photopatch testing in lomefloxacin photosensitivity.

    abstract::We report the results of scarified photopatch testing in 3 patients with photosensitivity to lomefloxacin, a new quinolone antibacterial agent introduced onto the Japanese market in April 1990. The patients developed pruritic eczematous lesions on sun-exposed areas 5 days to 3 weeks after they had started taking lomef...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1992.tb00860.x

    authors: Kurumaji Y,Shono M

    更新日期:1992-01-01 00:00:00

  • Clinical scoring and biophysical evaluation of nasolabial skin barrier damage caused by rhinorrhea.

    abstract:BACKGROUND:An acute viral cold is a very common illness and is characterized by sneezing and a runny nose. Because of rhinorrhea and frequent use of handkerchiefs, the skin around the nose feels uncomfortably dry and flaky. OBJECTIVES/METHODS:To evaluate the nasolabial skin barrier impairment, 14 female volunteers wit...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2008.01425.x

    authors: Houben E,Adam R,Hachem JP,Roseeuw D,Rogiers V,De Paepe K

    更新日期:2008-11-01 00:00:00

  • Cross-reaction patterns in patients with contact allergy to simple methylol phenols.

    abstract::The low-molecular-weight phenols 2-methylol phenol (2-MP), 4-methylol phenol (4-MP), 2,4,6-trimethylol phenol (2,4,6-MP), 3-methylol phenol (3-MP), 2,4-dimethylol phenol (2,4-MP), and 2,6-dimethylol phenol (2,6-MP) are contact sensitizers in resins based on phenol and formaldehyde (P-F-R). Other chemically related low...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1997.tb00044.x

    authors: Bruze M,Zimerson E

    更新日期:1997-08-01 00:00:00