Optimized enzymatic dual functions of PaPrx protein by proton irradiation.

abstract：:In patients with various cancers, modified Glasgow prognostic score (mGPS) before treatment has predicted prognoses after antitumor therapy. This study aimed to assess whether pretreatment mGPS also has predictive value in patients with muscle-invasive bladder cancer (MIBC) after radiotherapy. A retrospective review a...

journal_title：Journal of radiation research

authors： Kikuchi K,Nakamura R,Segawa T,Oikawa H,Ariga H

更新日期：2020-07-06 00:00:00

abstract：:Photon irradiation has been repeatedly suspected of increasing tumor cell motility and promoting locoregional recurrence of disease. This study was set up to analyse possible mechanisms underlying the potentially radiation-altered motility in medulloblastoma cells. Medulloblastoma cell lines D425 and Med8A were analyz...

journal_title：Journal of radiation research

authors： Rieken S,Rieber J,Brons S,Habermehl D,Rief H,Orschiedt L,Lindel K,Weber KJ,Debus J,Combs SE

更新日期：2015-05-01 00:00:00

abstract：:Gated radiation therapy is a promising method for improving the dose conformality of treatments to moving targets and reducing the total volume of irradiated tissue. Target motion is of particular concern in proton beam radiotherapy, due to the finite range of proton dose deposition in tissue. Gating allows one to red...

journal_title：Journal of radiation research

authors： Sharp GC,Lu HM,Trofimov A,Tang X,Jiang SB,Turcotte J,Gierga DP,Chen GT,Hong TS

更新日期：2007-01-01 00:00:00

abstract：:Perirectal hyaluronate gel injection (HGI) appears to be a promising technique for healthy tissue dose sparing in pelvic radiotherapy. In this analysis, we report our initial experience of HGI in gynecologic brachytherapy, focusing on its safety and effectiveness for dose reduction to the rectum. Between July 2013 and...

journal_title：Journal of radiation research

authors： Kashihara T,Murakami N,Tselis N,Kobayashi K,Tsuchida K,Shima S,Masui K,Yoshida K,Takahashi K,Inaba K,Umezawa R,Igaki H,Ito Y,Kato T,Uno T,Itami J

更新日期：2019-07-01 00:00:00

abstract：:While recent advances in elucidating the enzyme/substrate relationship of phosphorylation cascades have demonstrated several distinct pathways in membrane-cytoplasm signaling, the molecular dissection of p53 and the products of other proto-oncogenes have greatly promoted the studies of nuclear signaling and expanded t...

journal_title：Journal of radiation research

authors： Wang X,Ohnishi T

更新日期：1997-09-01 00:00:00

abstract：:The direct biological effects of radiation, particularly accelerated heavy particle ions, on neurons are not fully known. Hence, the direct effect of carbon-ion beams on immature neurons was investigated by comparing to the effect of X-rays in vitro using primary hippocampal neurons. Primary neurons were prepared from...

journal_title：Journal of radiation research

authors： Kaminuma T,Suzuki Y,Shirai K,Mizui T,Noda SE,Yoshida Y,Funayama T,Takahashi T,Kobayashi Y,Shirao T,Nakano T

更新日期：2010-01-01 00:00:00

abstract：:Irregular breathing can influence the outcome of 4D computed tomography imaging and cause artifacts. Visual biofeedback systems associated with a patient-specific guiding waveform are known to reduce respiratory irregularities. In Japan, abdomen and chest motion self-control devices (Abches) (representing simpler visu...

journal_title：Journal of radiation research

authors： Nakajima Y,Kadoya N,Kanai T,Ito K,Sato K,Dobashi S,Yamamoto T,Ishikawa Y,Matsushita H,Takeda K,Jingu K

更新日期：2016-07-01 00:00:00

abstract：:To evaluate the feasibility of using radiosensitivity of peripheral leukocytes as a predictor of clinical therapeutic responses to radiosurgery in individuals with cerebral arteriovenous malformation (AVM), we enrolled 18 patients years after they had received Gamma Knife radiosurgery for their cerebral AVM. The AVMs ...

journal_title：Journal of radiation research

authors： Guo WY,Pan HC,Wu HM,Hsieh WA,Tsai MH,Chow YM,Chung WY,Shiau CY,Chen SK,Chang WP

更新日期：2004-06-01 00:00:00

abstract：:Since December 2009, after breast-conserving surgery for Stage 0-I cancer of the left breast, 21 women with relatively pendulous breasts underwent computed tomography prone and supine simulations. The adjuvant radiotherapy was 50 Gy in 25 fractions to the left breast alone. Four plans--conventional wedged tangents and...

journal_title：Journal of radiation research

authors： Chen JL,Cheng JC,Kuo SH,Chan HM,Huang YS,Chen YH

更新日期：2013-09-01 00:00:00

abstract：:To assess the mutational effects of radiation on vigorously proliferating plant tissue, the mutation spectrum was analyzed with Arabidopsis seedlings using the plasmid-rescue method. Transgenic plants containing the Escherichia coli rpsL gene were irradiated with γ-rays and carbon ion beams (320-MeV (12)C(6+)), and mu...

journal_title：Journal of radiation research

authors： Yoshihara R,Nozawa S,Hase Y,Narumi I,Hidema J,Sakamoto AN

更新日期：2013-11-01 00:00:00

abstract：:Estimation of the relative biological effectiveness (RBE) of the proton beam at the National Cancer Center Proton Therapy Center in Korea (NCCPTC) is required clinically for the treatment of cancer. The proton beam was fixed at 190 MeV with 6 cm a spread out Bragg peaks (SOBP) for which corresponds to most frequent cl...

journal_title：Journal of radiation research

authors： Baek HJ,Kim TH,Shin D,Kwak JW,Choo DW,Lee SB,Furusawa Y,Ando K,Kim SS,Cho KH

更新日期：2008-09-01 00:00:00

abstract：:The purpose of this study was to describe the results of definitive radiotherapy (RT) with concurrent chemotherapy for maxillary sinus carcinomas (MSCs) with neck lymph node metastasis to clarify its limitation. Local control (LC), progression-free survival (PFS) and overall survival (OS) rates were calculated using t...

journal_title：Journal of radiation research

authors： Abe T,Saito S,Iino M,Aoshika T,Ryuno Y,Ohta T,Igari M,Hirai R,Kumazaki Y,Ebihara Y,Nakahira M,Sugasawa M,Noda SE,Kato S

更新日期：2021-01-01 00:00:00

abstract：:Massive release of radioactive materials into the atmosphere occurred due to the Fukushima Daiichi Nuclear Power Station (FDNPS) accident in March 2011. The World Health Organization (WHO) and the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) reported the results of dose estimation t...

journal_title：Journal of radiation research

authors： Miyatake H,Kawai M,Yoshizawa N,Suzuki G

更新日期：2020-03-23 00:00:00

abstract：:The present study was undertaken to determine relative biological effectiveness (RBE) values for simulated solar particle event (SPE) radiation on peripheral blood cells using Yucatan minipigs and electron-simulated SPE as the reference radiation. The results demonstrated a generally downward trend in the RBE values w...

journal_title：Journal of radiation research

authors： Sanzari JK,Wan SX,Diffenderfer ES,Cengel KA,Kennedy AR

更新日期：2014-03-01 00:00:00

abstract：:The objective of the present study was to estimate cancer risk associated with the low-level radiation exposure of an average annual effective dose of 6.4 mSv (including internal exposure) in the high background-radiation areas (HBRA) in Yangjiang, China. The mortality survey consisted of two steps, i.e., the follow-u...

journal_title：Journal of radiation research

authors： Tao Z,Zha Y,Akiba S,Sun Q,Zou J,Li J,Liu Y,Kato H,Sugahara T,Wei L

更新日期：2000-10-01 00:00:00

abstract：:A synergistic interaction of hyperthermia with ionizing or UV light (254 nm) radiation was analyzed in experiments with yeast cells. For a fixed dose rate of radiation, the synergism was shown to be observed only within a definite temperature range (40-45 degrees C), inside of which there was an optimal temperature to...

journal_title：Journal of radiation research

authors： Kim JK,Petin VG,Zhurakovskaya GP

更新日期：2001-12-01 00:00:00

abstract：:The rejoining efficiency of double-strand breaks (DSBs) was quantified by a DNA fragment-size analysis in tobacco protoplasts and CHO-K1 cells following gamma-ray irradiation in order to compare DNA reparability of higher plants with mammals. Results showed that the DSB rejoining efficiency of tobacco protoplasts is d...

journal_title：Journal of radiation research

authors： Yokota Y,Wada S,Hase Y,Funayama T,Kobayashi Y,Narumi I,Tanaka A

更新日期：2009-03-01 00:00:00

abstract：:The yield of OH radical induced by ionizing radiation was estimated by an empirical model; a prescribed diffusion model for a spur of single size applying to neutral water. Two representative spur distances were introduced, one for an incident primary charged particle and one for a representative secondary electron, t...

journal_title：Journal of radiation research

authors： Yamaguchi H,Uchihori Y,Yasuda N,Takada M,Kitamura H

更新日期：2005-09-01 00:00:00

abstract：:The aim of the study was to investigate the various effects of high linear energy transfer (LET) carbon ion (12C6+) and low LET X-ray radiation on MDA-MB-231 and MCF-7 human breast cancer cells and to explore the underlying mechanisms of radiation sensitivity. Cell proliferation, cell colony formation, cell cycle dist...

journal_title：Journal of radiation research

authors： Zhang Q,Kong Y,Yang Z,Liu Y,Liu R,Geng Y,Luo H,Zhang H,Li H,Feng S,Wang X

更新日期：2020-05-22 00:00:00

abstract：:In this study, a mechanism in which low-dose hyper-radiosensitivity (HRS) is permanently removed, induced by low-dose-rate (LDR) (0.2-0.3 Gy/h for 1 h) but not by high-dose-rate priming (0.3 Gy at 40 Gy/h) was investigated. One HRS-negative cell line (NHIK 3025) and two HRS-positive cell lines (T-47D, T98G) were used....

journal_title：Journal of radiation research

authors： Edin NJ,Sandvik JA,Vollan HS,Reger K,Görlach A,Pettersen EO

更新日期：2013-11-01 00:00:00

abstract：:Reactions of edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one) with deoxyguanosine monophosphate (dGMP) hydroxyl radical adducts were investigated by pulse radiolysis technique. Edaravone was found to reduce the dGMP hydroxyl radical adducts through electron transfer reactions. The rate constants of the reactions were g...

journal_title：Journal of radiation research

authors： Hata K,Urushibara A,Yamashita S,Lin M,Muroya Y,Shikazono N,Yokoya A,Fu H,Katsumura Y

更新日期：2015-01-01 00:00:00

abstract：:The purpose of this study is to survey the current patterns of practice, and barriers to implementation, of 3D image-guided brachytherapy (3D-IGBT) for cervical cancer in Japan. A 30-item questionnaire was sent to 171 Japanese facilities where high-dose-rate brachytherapy devices were available in 2012. In total, 135 ...

journal_title：Journal of radiation research

authors： Ohno T,Toita T,Tsujino K,Uchida N,Hatano K,Nishimura T,Ishikura S

更新日期：2015-11-01 00:00:00

abstract：:Intrafractional motion and interfractional changes affect the accuracy of the delivered dose in radiotherapy, particularly in charged-particle radiotherapy. Most recent studies are focused on intrafractional motion (respiratory motion). Here, we report a quantitative simulation analysis of the effects of interfraction...

journal_title：Journal of radiation research

authors： Mori S,Lu HM,Wolfgang JA,Choi NC,Chen GT

更新日期：2009-11-01 00:00:00

abstract：:The purpose of this study was to analyze the dosimetry and investigate the clinical outcomes of radiation-induced rib fractures (RIRFs) after stereotactic body radiotherapy (SBRT). A total of 126 patients with Stage I primary lung cancer treated with SBRT, who had undergone follow-up computed tomography (CT) at least ...

journal_title：Journal of radiation research

authors： Miura H,Inoue T,Shiomi H,Oh RJ

更新日期：2015-03-01 00:00:00

abstract：:The purpose of this study was to assess the toxicity and efficacy of multimodal approaches, including three-dimensional conformal re-irradiation, for patients with recurrent or persistent esophageal cancer after radiotherapy. Thirty-one patients with esophageal cancer treated with three-dimensional conformal re-irradi...

journal_title：Journal of radiation research

authors： Yamaguchi S,Ohguri T,Imada H,Yahara K,Moon SD,Higure A,Yamaguchi K,Yoshikawa I,Harada M,Korogi Y

更新日期：2011-01-01 00:00:00

abstract：:The purpose of this study was to quantify the changes of tumor blood flow (BF) in cervical cancer after radiation therapy by using perfusion computed tomography (CT), and to examine the difference between maximum slope (MS) and single-input one-compartment model (SOCM) methods. Fourteen consecutive patients who receiv...

journal_title：Journal of radiation research

authors： Shibuya K,Tsushima Y,Horisoko E,Noda SE,Taketomi-Takahashi A,Ohno T,Amanuma M,Endo K,Nakano T

更新日期：2011-01-01 00:00:00

abstract：:Thyroid cells were given 5.5 Gy X-rays in situ and transplanted after 1 day or after 6 weeks to form colonies in fat pads. The colony-forming efficiency unexpectedly decreased by a factor of about 2 with this increase in delay time before transplantation. In addition, there was a concomitant marked increase above the ...

journal_title：Journal of radiation research

authors： Watanabe H,Hendry JH

更新日期：1994-06-01 00:00:00

abstract：:The radioprotective activity of the hydroalcoholic extract of jamun seeds (SCE) was studied in mice exposed to different doses of gamma radiation. The mice were injected with 0, 5, 10, 20, 40, 60, 80, 100, 120, 140 or 160 mg/kg body weight of SCE, before exposure to 10 Gy of gamma radiation, to select the optimum dose...

journal_title：Journal of radiation research

authors： Jagetia GC,Baliga MS,Venkatesh P

更新日期：2005-03-01 00:00:00

abstract：:The quality of the sublethal damage (SLD) after irradiation with high-linear energy transfer (LET) ion beams was investigated with low-LET photons. Chinese hamster V79 cells and human squamous carcinoma SAS cells were first exposed to a priming dose of different ion beams at different LETs at the Heavy Ion Medical Acc...

journal_title：Journal of radiation research

authors： Furusawa Y,Nakano-Aoki M,Matsumoto Y,Hirayama R,Kobayashi A,Konishi T

更新日期：2017-11-01 00:00:00

abstract：:We examined the effect of whole body low-dose gamma-irradiation on the status of the antioxidant defense system in the rodent kidneys at different time intervals. Young male Balb/c mice were exposed to whole body radiation from a (60)Co source at doses of 10, 25 and 50 cGy (48.78 cGy/min). Antioxidant status and lipid...

journal_title：Journal of radiation research

authors： Pathak CM,Avti PK,Kumar S,Khanduja KL,Sharma SC

更新日期：2007-03-01 00:00:00