Estimation of yields of OH radicals in water irradiated by ionizing radiation.

abstract：:We investigated the sensitizing effect of the 2-nitroimidazole analogue doranidazole, a new hypoxic radiosensitizer, on radiation-induced apoptosis in L5178Y cells. Apoptosis was assessed by checking DNA ladder formation, the presence of sub-G1 peaks in flow cytometry, and chromatin condensation. A radiosensitizing ef...

journal_title：Journal of radiation research

authors： Aoki M,Furusawa Y,Shibamoto Y,Kobayashi A,Tsujitani M

更新日期：2002-06-01 00:00:00

abstract：:Toll-like receptors (TLRs) are pattern recognition receptors that recognize pathogen-associated molecular patterns and are indispensable for antibacterial and antiviral immunity. Our previous report showed that ionizing radiation increases the cell surface expressions of TLR2 and TLR4 and enhances their responses to a...

journal_title：Journal of radiation research

authors： Yoshino H,Kashiwakura I

更新日期：2017-09-01 00:00:00

abstract：:The effect of gamma-irradiation on a major nutritional function of the yolk sac (the uptake and digestion of macromolecular materials) was studied in rat visceral yolk sacs cultured in vitro being used 125I-labeled bovine serum albumin (RISA) as the tracer protein. The uptake of RISA (per g wet weight) by rat yolk sac...

journal_title：Journal of radiation research

authors： Takahashi S,Koshimoto C,Kubota Y

更新日期：1993-06-01 00:00:00

abstract：:The purpose of this study was to evaluate interfractional changes of the minimum dose delivered to 90% of the high-risk clinical target volume (HR-CTV D90) and D2cc of the bladder and rectum during brachytherapy for uterine cervical cancer patients. A total of 52 patients received external beam radiotherapy and high-d...

journal_title：Journal of radiation research

authors： Ohkubo Y,Ohno T,Noda SE,Kubo N,Nakagawa A,Kawahara M,Abe T,Kiyohara H,Wakatsuki M,Nakano T

更新日期：2013-11-01 00:00:00

abstract：:This study investigated the radioprotective effect of Sipunculus nudus L. polysaccharide (SNP) in combination with WR-2721, rhIL-11 and rhG-CSF on irradiated mice. A total of 70 Imprinting Control Region (ICR) mice were divided into seven groups: the control group, the model group and five administration groups. All g...

journal_title：Journal of radiation research

authors： Jiang S,Shen X,Liu Y,He Y,Jiang D,Chen W

更新日期：2015-05-01 00:00:00

abstract：:The radioprotective effect of hawthorn (Crataegus microphylla) fruit extract against genotoxicity induced by gamma irradiation has been investigated in mouse bone marrow cells. A single intraperitoneal (ip) administration of hawthorn extract at doses of 25, 50, 100 and 200 mg/kg 1h prior to gamma irradiation (2 Gy) re...

journal_title：Journal of radiation research

authors： Hosseinimehr SJ,Azadbakht M,Mousavi SM,Mahmoudzadeh A,Akhlaghpoor S

更新日期：2007-01-01 00:00:00

abstract：:Preliminary results of the Polish epidemiology study on eye lens opacities among interventional cardiologists (ICs), based on the methodology proposed by ELDO (epidemiological studies of radio-induced cataracts in interventional cardiologists and radiologists: methodology implementation), are presented. The aim of the...

journal_title：Journal of radiation research

authors： Domienik J,Gryglak S,Jurewicz J

更新日期：2016-07-01 00:00:00

abstract：:Development of a curative local treatment for large hepatocellular carcinoma (HCC) is an important issue. Here, we investigated the dose homogeneity, safety and antitumor effectiveness of proton beam therapy (PBT) using a patch-field technique for large HCC. Data from nine patients (aged 52-79 years) with large HCC tr...

journal_title：Journal of radiation research

authors： Nakamura M,Fukumitsu N,Kamizawa S,Numajiri H,Nemoto Murofushi K,Ohnishi K,Aihara T,Ishikawa H,Okumura T,Tsuboi K,Sakurai H

更新日期：2018-09-01 00:00:00

abstract：:3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) is known to be a mutagen and carcinogen isolated from the charred parts of cooked foods. We found previously that Trp-P-1 enhanced UV-induced lethality and mutation frequency in Escherichia coli by inhibiting the repair of UV-induced DNA damage. In the present stud...

journal_title：Journal of radiation research

authors： Mori T,Nakagawa A,Kobayashi N,Hashimoto MW,Wakabayashi K,Shimoi K,Kinae N

更新日期：1998-03-01 00:00:00

abstract：:Liquid ionization chambers (LICs) are highly sensitive to dose irradiation and have small perturbations because of their liquid-filled sensitive volume. They require a sensitive volume much smaller than conventional air-filled chambers. However, it has been reported that the collection efficiency has dependencies on t...

journal_title：Journal of radiation research

authors： Takei H,Isobe T,Kitamura N,Mori Y,Tomita T,Kobayashi D,Kamizawa S,Sato T,Sakurai H,Sakae T

更新日期：2018-05-01 00:00:00

abstract：:In the 1970s and 1980s, Planel et al. reported that the growth of paramecia was decreased by shielding them from background radiation. In the 1990s, Takizawa et al. found that mouse cells displayed a decreased growth rate under shielded conditions. The purpose of the present study was to confirm that growth is impaire...

journal_title：Journal of radiation research

authors： Kawanishi M,Okuyama K,Shiraishi K,Matsuda Y,Taniguchi R,Shiomi N,Yonezawa M,Yagi T

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The aim of this study is to evaluate the cost-effectiveness of proton beam therapy with cochlear dose reduction compared with conventional X-ray radiotherapy for medulloblastoma in childhood. METHODS:We developed a Markov model to describe health states of 6-year-old children with medulloblastoma after trea...

journal_title：Journal of radiation research

authors： Hirano E,Fuji H,Onoe T,Kumar V,Shirato H,Kawabuchi K

更新日期：2014-03-01 00:00:00

abstract：:We investigated the efficacy and safety of albumin-bound paclitaxel (nab-PTX) and carboplatin (CBDCA) with concurrent radiotherapy for unresectable locally advanced non-small-cell lung cancer (NSCLC). Patients with Stage III NSCLC and an Eastern Cooperative Oncology Group performance status of 0 or 1 were eligible. Co...

journal_title：Journal of radiation research

authors： Hasegawa T,Futamura Y,Horiba A,Yoshida T,Suzuki T,Kato T,Kaito D,Ohno Y,Iida T,Hayashi S,Sawa T

更新日期：2016-01-01 00:00:00

abstract：:Boron neutron capture therapy (BNCT) is an emerging radiation treatment modality, exhibiting the potential to selectively destroy cancer cells. Currently, BNCT is conducted using a nuclear reactor. However, the future trend is to move toward an accelerator-based system for use in hospital environments. A typical BNCT ...

journal_title：Journal of radiation research

authors： Hu N,Tanaka H,Takata T,Okazaki K,Uchida R,Sakurai Y

更新日期：2020-03-23 00:00:00

abstract：:The purpose of this study was to assess the toxicity and efficacy of multimodal approaches, including three-dimensional conformal re-irradiation, for patients with recurrent or persistent esophageal cancer after radiotherapy. Thirty-one patients with esophageal cancer treated with three-dimensional conformal re-irradi...

journal_title：Journal of radiation research

authors： Yamaguchi S,Ohguri T,Imada H,Yahara K,Moon SD,Higure A,Yamaguchi K,Yoshikawa I,Harada M,Korogi Y

更新日期：2011-01-01 00:00:00

abstract：:In this study, a novel combination treatment of armed oncolytic adenovirus expressing interleukin 12 (IL-12) and granulocyte-macrophage colony-stimulating factor (GM-CSF) with radiation was investigated for antitumor and antimetastatic effect in a murine hepatic cancer (HCa-I) model. Tumor bearing syngeneic mice were ...

journal_title：Journal of radiation research

authors： Kim W,Seong J,Oh HJ,Koom WS,Choi KJ,Yun CO

更新日期：2011-01-01 00:00:00

abstract：:The purpose of this study is to investigate the normal tissue damage caused by carbon-ion therapy. We measured chromosomal aberrations in peripheral blood lymphocytes before, during, and after radiotherapy, using the techniques of fluorescence in situ hybridization (FISH) and chemically induced premature chromosome co...

journal_title：Journal of radiation research

authors： Lee R,Yamada S,Yamamoto N,Miyamoto T,Ando K,Durante M,Tsujii H

更新日期：2004-06-01 00:00:00

abstract：:This project aimed to set up a Beagle dog model of radiation-induced lung injury in order to supply fresh lung tissue samples in the different injury phases for gene and protein research. Three dogs received 18 Gy X-ray irradiation in one fraction, another three dogs received 8 Gy in each of three fractions at weekly ...

journal_title：Journal of radiation research

authors： Yin Z,Deng S,Liang Z,Wang Q

更新日期：2016-09-01 00:00:00

abstract：:Whole brain irradiation (WBI) has become an indispensible tool in the treatment of head and neck cancer, and it has greatly improved patient survival rate and total survival time. In addition, prophylactic cranial irradiation (PCI) has dramatically decreased the incidence of brain metastatic carcinoma. However, WBI ma...

journal_title：Journal of radiation research

authors： Xu M,Fan Q,Zhang J,Chen Y,Xu R,Chen L,Zhao P,Tian Y

更新日期：2017-11-01 00:00:00

abstract：:To assess the mutational effects of radiation on vigorously proliferating plant tissue, the mutation spectrum was analyzed with Arabidopsis seedlings using the plasmid-rescue method. Transgenic plants containing the Escherichia coli rpsL gene were irradiated with γ-rays and carbon ion beams (320-MeV (12)C(6+)), and mu...

journal_title：Journal of radiation research

authors： Yoshihara R,Nozawa S,Hase Y,Narumi I,Hidema J,Sakamoto AN

更新日期：2013-11-01 00:00:00

abstract：:The purpose of the study was to quantify local setup errors and evaluate the planning target volume (PTV) margins for sub-regions in cone-beam computed tomography (CBCT)-guided post-mastectomy radiation therapy (PMRT). The local setup errors of 20 patients undergoing CBCT-guided PMRT were analysed retrospectively. Ima...

journal_title：Journal of radiation research

authors： Zhou J,Li S,Ye C,Shen K,Li A,Chen G,Li X,Bai S,Wang W,Zhong R

更新日期：2020-05-22 00:00:00

abstract：:The purpose of this study was to compare single-arc (SA) and double-arc (DA) treatment plans, which are planning techniques often used in prostate cancer volumetric modulated arc therapy (VMAT), in the presence of intrafractional deformation (ID) to determine which technique is superior in terms of target dose coverag...

journal_title：Journal of radiation research

authors： Varnava M,Sumida I,Oda M,Kurosu K,Isohashi F,Seo Y,Otani K,Ogawa K

更新日期：2020-12-21 00:00:00

abstract：:Respiratory motion management is a huge challenge in radiation therapy. Respiratory motion induces temporal anatomic changes that distort the tumor volume and its position. In this study, a markerless tumor-tracking algorithm was investigated by performing phase recognition during stereotactic body radiation therapy (...

journal_title：Journal of radiation research

authors： Bhusal Chhatkuli R,Demachi K,Uesaka M,Nakagawa K,Haga A

更新日期：2019-01-01 00:00:00

abstract：:Millimeter waves are used in various fields, and the risks of this wavelength range for human health must be carefully evaluated. In this study, we investigated the effects of millimeter waves on genotoxicity and heat shock protein expression in human corneal epithelial (HCE-T) and human lens epithelial (SRA01/04) cel...

journal_title：Journal of radiation research

authors： Koyama S,Narita E,Suzuki Y,Shiina T,Taki M,Shinohara N,Miyakoshi J

更新日期：2019-07-01 00:00:00

abstract：:There is an urgent need to develop non-toxic radioprotectors. We tested the efficacy of a 3-drug combination (3-DC) of iloprost, misoprostol, and 3D-MPL (3-deacylated monophosphoryl lipid A) and the effects of postirradiation clinical support with high doses of antibiotics and blood transfusion. Canines were given 3-D...

journal_title：Journal of radiation research

authors： Kumar KS,Srinivasan V,Toles RE,Miner VL,Jackson WE,Seed TM

更新日期：2002-12-01 00:00:00

abstract：:Radiation therapy (RT) has become particularly important recently for treatment of liver tumors, but there are few experimental investigations pertaining to radiation-induced liver injuries over long-term follow-up periods. Thus, the present study examined pathological liver features over a 10-month period using an in...

journal_title：Journal of radiation research

authors： Imaeda M,Ishikawa H,Yoshida Y,Takahashi T,Ohkubo Y,Musha A,Komachi M,Nakazato Y,Nakano T

更新日期：2014-07-01 00:00:00

abstract：:Thyroid cells were given 5.5 Gy X-rays in situ and transplanted after 1 day or after 6 weeks to form colonies in fat pads. The colony-forming efficiency unexpectedly decreased by a factor of about 2 with this increase in delay time before transplantation. In addition, there was a concomitant marked increase above the ...

journal_title：Journal of radiation research

authors： Watanabe H,Hendry JH

更新日期：1994-06-01 00:00:00

abstract：:The aim of this study is to evaluate the potential radioprotective effects of N-acetylcysteine (NAC) against genotoxicity and cytotoxicity. The effect of WR-2721, as a representative of clinically used radioprotector, was compared with that of NAC, using the chromosomal aberration (CA) and micronucleus (MN) test syste...

journal_title：Journal of radiation research

authors： Demirel C,Kilçiksiz S,Ay OI,Gürgül S,Ay ME,Erdal N

更新日期：2009-01-01 00:00:00

abstract：:To investigate the importance of gender and aging on the individual radiosensitivity of lineage-committed myeloid hematopoietic stem/progenitor cells (HSPCs) detected in mononuclear cells (MNCs) of steady-state human peripheral blood (PB), the clonogenic survival of HPCs, including colony-forming unit-granulocyte macr...

journal_title：Journal of radiation research

authors： Kato K,Kuwabara M,Kashiwakura I

更新日期：2011-01-01 00:00:00

abstract：:We evaluated the radiological response and clinical outcome in patients with femoral bone metastases after radiotherapy. 102 consecutive patients with femoral metastases without pathological fracture were treated by surgery or radiotherapy between 2002 and 2005. Twelve of them initially treated with surgery were exclu...

journal_title：Journal of radiation research

authors： Harada H,Katagiri H,Kamata M,Yoshioka Y,Asakura H,Hashimoto T,Furutani K,Takahashi M,Sakahara H,Nishimura T

更新日期：2010-01-01 00:00:00