A phase II study of nab-paclitaxel plus carboplatin in combination with thoracic radiation in patients with locally advanced non-small-cell lung cancer.

abstract：:The aim of this study is to demonstrate the feasibility of estimating the strength of the moving radiation source during patient implantation. The requirement for the counting time was investigated by comparing the results of the measurements for the static source with those for the source moving at 2, 5, 10 and 20 cm...

journal_title：Journal of radiation research

authors： Tanaka K,Endo S,Tateoka K,Asanuma O,Kamo K,Sato K,Takeda H,Takagi M,Hareyama M,Takada J

更新日期：2014-01-01 00:00:00

abstract：:In patients with various cancers, modified Glasgow prognostic score (mGPS) before treatment has predicted prognoses after antitumor therapy. This study aimed to assess whether pretreatment mGPS also has predictive value in patients with muscle-invasive bladder cancer (MIBC) after radiotherapy. A retrospective review a...

journal_title：Journal of radiation research

authors： Kikuchi K,Nakamura R,Segawa T,Oikawa H,Ariga H

更新日期：2020-07-06 00:00:00

abstract：:X-ray induced formation of micronuclei is generally thought to result from DNA double-strand breaks (DSBs). However, DNA DSBs inhibit the cell cycle progression that is required for micronucleus formation. In order to reconcile this apparent discrepancy, we investigated whether DNA DSBs induced during the G1 phase cou...

journal_title：Journal of radiation research

authors： Okada T,Kashino G,Nishiura H,Tano K,Watanabe M

更新日期：2012-01-01 00:00:00

abstract：:The purpose of this study was to analyze the patterns of care and outcomes of patients with FIGO Stage I/II cervical cancer who underwent definitive radiotherapy (RT) at multiple Japanese institutions. The Japanese Radiation Oncology Study Group (JROSG) performed a questionnaire-based survey of their cervical cancer p...

journal_title：Journal of radiation research

authors： Ariga T,Toita T,Kato S,Kazumoto T,Kubozono M,Tokumaru S,Eto H,Nishimura T,Niibe Y,Nakata K,Kaneyasu Y,Nonoshita T,Uno T,Ohno T,Iwata H,Harima Y,Wada H,Yoshida K,Gomi H,Numasaki H,Teshima T,Yamada S,Nakano T

更新日期：2015-09-01 00:00:00

abstract：:We examined the use of the mouse Pc-3 ESTR (expanded simple tandem repeat) locus and 72 human microsatellite loci as potentially sensitive biomarkers for mutagenic exposures to germ cells in mice and humans respectively. In the mouse work, we treated male mice with TCDD (2, 3, 7, 8-tetrachlorodibenzo-p-dioxin; a chemi...

journal_title：Journal of radiation research

authors： Ryo H,Nakajima H,Nomura T

更新日期：2006-01-01 00:00:00

abstract：:The fertility span between the first and the last estrus was compared among female Chinese hamsters exposed to 1 Gy X-rays on neonatal day 0, 2, 4, 6, 8, 10 and 14. The fertility span changed dramatically according to the age at the time of irradiation. The females irradiated on day 4, 6 and 8 showed a definite delay ...

journal_title：Journal of radiation research

authors： Tateno H,Mikamo K

更新日期：1989-06-01 00:00:00

abstract：:Due to the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident, the evacuees from Namie Town still cannot reside in the town, and some continue to live in temporary housing units. In this study, the radon activity concentrations were measured at temporary housing facilities, apartments and detached houses in Fukush...

journal_title：Journal of radiation research

authors： Hosoda M,Tokonami S,Omori Y,Ishikawa T,Iwaoka K

更新日期：2016-07-01 00:00:00

abstract：:Radiation-induced bystander effects (RIBEs) are detected in cells that are not irradiated but receive signals from treated cells. The present study explored these bystander effects in a U87MG multicellular tumour spheroid model. A medium transfer technique was employed to induce the bystander effect, and colony format...

journal_title：Journal of radiation research

authors： Faqihi F,Neshastehriz A,Soleymanifard S,Shabani R,Eivazzadeh N

更新日期：2015-09-01 00:00:00

abstract：:Previous studies have demonstrated that X-ray irradiation affects angiogenesis in tumors. Here, we studied the effects of gamma-ray irradiation on boron-10 compound accumulation in a murine tumor model. The mouse squamous cell carcinoma was irradiated with gamma-ray before BSH ((10)B-enriched borocaptate sodium) admin...

journal_title：Journal of radiation research

authors： Liu Y,Nagata K,Masunaga S,Suzuki M,Kashino G,Kinashi Y,Tanaka H,Sakurai Y,Maruhashi A,Ono K

更新日期：2009-11-01 00:00:00

abstract：:Paired Fricke solutions, made up from light water or heavy water and 0.8N in H2SO4 and 1 mM in Fe(NH4)2(SO4)2 and NaCl, were calibrated with 60Co gamma rays and with mixed neutron and gamma radiation from a 252Cf source. Absorbance increases, AL and AH, in light- and heavy-water Fricke dosimeters, respectively, increa...

journal_title：Journal of radiation research

authors： Himit M,Itoh T,Endo S,Fujikawa K,Hoshi M

更新日期：1996-06-01 00:00:00

abstract：:We investigated the effects of proton irradiation on the function and structure of the Pseudomonas aeruginosa peroxiredoxin (PaPrx). Polyacrylamide gel demonstrated that PaPrx proteins exposed to proton irradiation at several doses exhibited simultaneous formation of high molecular weight (HMW) complexes and fragmenta...

journal_title：Journal of radiation research

authors： Park CH,Lee SS,Kim KR,Jung MH,Lee SY,Cho EJ,Singh S,Chung BY

更新日期：2014-01-01 00:00:00

abstract：:The purpose of this study was to analyze the dosimetry and investigate the clinical outcomes of radiation-induced rib fractures (RIRFs) after stereotactic body radiotherapy (SBRT). A total of 126 patients with Stage I primary lung cancer treated with SBRT, who had undergone follow-up computed tomography (CT) at least ...

journal_title：Journal of radiation research

authors： Miura H,Inoue T,Shiomi H,Oh RJ

更新日期：2015-03-01 00:00:00

abstract：:Based on the accumulating evidence for equivalent results of partial-breast irradiation (PBI) and whole-breast irradiation (WBI) in breast-conserving therapy (BCT), the American Society for Radiation Oncology (ASTRO) updated the consensus statement (CS) to expand the range of potential candidates for PBI outside clini...

journal_title：Journal of radiation research

authors： Sato K,Fuchikami H,Takeda N,Kato M,Shimo T,Okawa T

更新日期：2018-05-01 00:00:00

abstract：:Millimeter waves are used in various fields, and the risks of this wavelength range for human health must be carefully evaluated. In this study, we investigated the effects of millimeter waves on genotoxicity and heat shock protein expression in human corneal epithelial (HCE-T) and human lens epithelial (SRA01/04) cel...

journal_title：Journal of radiation research

authors： Koyama S,Narita E,Suzuki Y,Shiina T,Taki M,Shinohara N,Miyakoshi J

更新日期：2019-07-01 00:00:00

abstract：:The aim of this study was to determine the outcomes and adverse events for 300 men with prostate cancer treated with 125iodine (125I) brachytherapy with and without external-beam radiation therapy (EBRT) at a single institution in Japan. Between February 2005 and November 2011, 300 consecutive patients with clinically...

journal_title：Journal of radiation research

authors： Maki S,Itoh Y,Kubota S,Okada T,Nakahara R,Ito J,Kawamura M,Naganawa S,Yoshino Y,Fujita T,Kato M,Gotoh M,Ikeda M

更新日期：2017-11-01 00:00:00

abstract：:We examined the effect of an extremely low-frequency magnetic field (ELFMF) at 5, 50 and 400 mT on DNA strand breaks in human glioma MO54 cells. A DNA damage analysis was performed using the method of alkaline comet assay. The cells were exposed to X-rays alone (5 Gy), ELFMF alone, or X-rays followed by ELFMF at 4 deg...

journal_title：Journal of radiation research

authors： Miyakoshi J,Yoshida M,Shibuya K,Hiraoka M

更新日期：2000-09-01 00:00:00

abstract：:Ionizing radiation induces biological effects not only in irradiated cells but also in non-irradiated cells, which is called the bystander effect. Recently, in vivo and in vitro experiments have suggested that both gap junction hemichannel connexin43 (Cx43) and extracellular adenosine triphosphate (ATP) released from ...

journal_title：Journal of radiation research

authors： Ohshima Y,Tsukimoto M,Harada H,Kojima S

更新日期：2012-07-01 00:00:00

abstract：:Several models for the action of mixed irradiation with two types of radiation have been proposed in the last two decades, although the superiority or inferiority of these models is not completely elucidated. However, mixed irradiation is sometimes composed of more than two types of radiation, and for this type of mix...

journal_title：Journal of radiation research

authors： Suzuki S

更新日期：1998-09-01 00:00:00

abstract：:Carbon-ion therapy by layer-stacking irradiation for static targets has been practised in clinical treatments. In order to apply this technique to a moving target, disturbances of carbon-ion dose distributions due to respiratory motion have been studied based on the measurement using a respiratory motion phantom, and ...

journal_title：Journal of radiation research

authors： Tajiri S,Tashiro M,Mizukami T,Tsukishima C,Torikoshi M,Kanai T

更新日期：2017-11-01 00:00:00

abstract：:The Rho-associated coiled-coil-containing protein kinase (ROCK) pathway is known to influence metastasis in several cancers; however, the impact of the pathway on clinical outcomes in patients undergoing radiotherapy remains unknown. In the present study, the expression of RhoA, RhoC, ROCK-1, ROCK-2 and p53 was immuno...

journal_title：Journal of radiation research

authors： Tanaka K,Matsumoto Y,Ishikawa H,Fukumitsu N,Numajiri H,Murofushi K,Oshiro Y,Okumura T,Satoh T,Sakurai H

更新日期：2020-03-23 00:00:00

abstract：:The purpose of the present study was to develop a hybrid magnetic resonance/computed tomography (MR/CT)-compatible phantom and tissue-equivalent materials for each MR and CT image. Therefore, the essential requirements necessary for the development of a hybrid MR/CT-compatible phantom were determined and the developme...

journal_title：Journal of radiation research

authors： Kim MJ,Lee SR,Song KH,Baek HM,Choe BY,Suh TS

更新日期：2020-03-23 00:00:00

abstract：:We evaluated the interrelationship between rectal content and intrafraction motion of the prostate. Forty seven prostate cancer patients instructed to remove their rectal gas were imaged by planning CT and MRI before radiotherapy (RT) and during RT. The total scan time was comparable to our cone-beam CT scanning and t...

journal_title：Journal of radiation research

authors： Ogino I,Kaneko T,Suzuki R,Matsui T,Takebayashi S,Inoue T,Morita S

更新日期：2011-01-01 00:00:00

abstract：:Disufiram (a drug used for the treatment of alcoholism) protected microsomal membranes and plasmid DNA against damages induced by gamma-radiation. The peroxidation of membrane lipids increased linearly with the radiation dose up to 600 Gy, and the presence of disulfiram inhibited membrane lipid peroxidation as assayed...

journal_title：Journal of radiation research

authors： Gandhi NM,Gopalaswamy UV,Nair Cr

更新日期：2003-09-01 00:00:00

abstract：:To determine the patterns of gene expression responsible for the radiosensitivity of glioblastoma cells, we analyzed transcriptional changes after ionizing radiation in different cell lines. After completing clonogenic survival assays, we selected two glioblastoma cell lines with different radiosensitivities. Subseque...

journal_title：Journal of radiation research

authors： Otomo T,Hishii M,Arai H,Sato K,Sasai K

更新日期：2004-03-01 00:00:00

abstract：:The aim of this study is to evaluate the potential radioprotective effects of N-acetylcysteine (NAC) against genotoxicity and cytotoxicity. The effect of WR-2721, as a representative of clinically used radioprotector, was compared with that of NAC, using the chromosomal aberration (CA) and micronucleus (MN) test syste...

journal_title：Journal of radiation research

authors： Demirel C,Kilçiksiz S,Ay OI,Gürgül S,Ay ME,Erdal N

更新日期：2009-01-01 00:00:00

abstract：:Radiation therapy (RT) has become particularly important recently for treatment of liver tumors, but there are few experimental investigations pertaining to radiation-induced liver injuries over long-term follow-up periods. Thus, the present study examined pathological liver features over a 10-month period using an in...

journal_title：Journal of radiation research

authors： Imaeda M,Ishikawa H,Yoshida Y,Takahashi T,Ohkubo Y,Musha A,Komachi M,Nakazato Y,Nakano T

更新日期：2014-07-01 00:00:00

abstract：:This study investigated the radioprotective effect of Sipunculus nudus L. polysaccharide (SNP) in combination with WR-2721, rhIL-11 and rhG-CSF on irradiated mice. A total of 70 Imprinting Control Region (ICR) mice were divided into seven groups: the control group, the model group and five administration groups. All g...

journal_title：Journal of radiation research

authors： Jiang S,Shen X,Liu Y,He Y,Jiang D,Chen W

更新日期：2015-05-01 00:00:00

abstract：:Medical diagnostic X-ray workers are one occupational group that has exposure to continuous low doses of external radiation over their working lifetimes. Current ICRP recommendations [ICRP. Recommendations of the International Commission on Radiological Protection. ICRP Publication 60. Ann ICRP 1991;21 (1-3)] state th...

journal_title：Journal of radiation research

authors： Xu XS,Zhang LA,Sun QF,Qin YC,Yu NL

更新日期：2018-03-01 00:00:00

abstract：:Before the sorafenib era, advanced but liver-confined hepatocellular carcinoma (HCC) was treated by liver-directed therapy. Hepatic arterial concurrent chemoradiotherapy (CCRT) has been performed in our group, giving substantial local control but frequent failure. The aim of this study was to analyze patterns of failu...

journal_title：Journal of radiation research

authors： Cha H,Yoon HI,Lee IJ,Koom WS,Han KH,Seong J

更新日期：2013-11-01 00:00:00

abstract：:In our previous studies, we found that low-dose radiation inhibits oxidative stress-induced diseases due to increased antioxidants. Although these effects of low-dose radiation were demonstrated, further research was needed to clarify the effects. However, the analysis of oxidative stress is challenging, especially th...

journal_title：Journal of radiation research

authors： Kanzaki N,Kataoka T,Etani R,Sasaoka K,Kanagawa A,Yamaoka K

更新日期：2017-01-01 00:00:00