Micronuclei formation induced by X-ray irradiation does not always result from DNA double-strand breaks.

abstract：:Radiotherapy is an integral part of overall cancer therapy. One of the most serious adverse effects of irradiation concern, for long-term survivors, the development of post-radiation sarcoma (PRS) in healthy tissues located within the irradiated area. PRS have bad prognosis and are often detected at a late stage. Ther...

journal_title：Journal of radiation research

authors： Phulpin B,Tran N,Leroux A,Poussier S,Marie PY,Pinel S,Huger S,Henrot P,Gallet P,Blaise C,Bravetti P,Graff P,Merlin JL,Dolivet G

更新日期：2012-01-01 00:00:00

abstract：:The aim of this study was to evaluate the effectiveness and tolerability of definitive chemo-radiation or radiotherapy alone in patients with esophageal cancer. We retrospectively analyzed the medical records of n = 238 patients with squamous cell carcinoma or adenocarcinoma of the esophagus treated with definitive ra...

journal_title：Journal of radiation research

authors： Haefner MF,Lang K,Krug D,Koerber SA,Uhlmann L,Kieser M,Debus J,Sterzing F

更新日期：2015-07-01 00:00:00

abstract：:The present study was undertaken to determine relative biological effectiveness (RBE) values for simulated solar particle event (SPE) radiation on peripheral blood cells using Yucatan minipigs and electron-simulated SPE as the reference radiation. The results demonstrated a generally downward trend in the RBE values w...

journal_title：Journal of radiation research

authors： Sanzari JK,Wan SX,Diffenderfer ES,Cengel KA,Kennedy AR

更新日期：2014-03-01 00:00:00

abstract：:3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) is known to be a mutagen and carcinogen isolated from the charred parts of cooked foods. We found previously that Trp-P-1 enhanced UV-induced lethality and mutation frequency in Escherichia coli by inhibiting the repair of UV-induced DNA damage. In the present stud...

journal_title：Journal of radiation research

authors： Mori T,Nakagawa A,Kobayashi N,Hashimoto MW,Wakabayashi K,Shimoi K,Kinae N

更新日期：1998-03-01 00:00:00

abstract：:Wistar rats inhaled 239PuO2 particles prepared by the calcination of 239Pu hydroxide at 1150 and 400 degrees C. Lung retention, fecal and urinary excretion, and translocation of 239Pu were compared between the two calcination temperatures. The clearance of 239Pu from the lungs was significantly faster in the rats expo...

journal_title：Journal of radiation research

authors： Sato H,Yamada Y,Ishigure N,Nakano T,Enomoto H,Takahashi S,Kubota Y,Inaba J

更新日期：1999-06-01 00:00:00

abstract：:Radiation-induced bystander effects (RIBEs) are detected in cells that are not irradiated but receive signals from treated cells. The present study explored these bystander effects in a U87MG multicellular tumour spheroid model. A medium transfer technique was employed to induce the bystander effect, and colony format...

journal_title：Journal of radiation research

authors： Faqihi F,Neshastehriz A,Soleymanifard S,Shabani R,Eivazzadeh N

更新日期：2015-09-01 00:00:00

abstract：:This retrospective analysis focusses on the impact of therapy on perceived long-term post-cancer treatment function. A validated questionnaire including items and components for the assessment of communicative ability, quality of voice and swallowing was sent to 129 patients. All patients were treated between 1998 and...

journal_title：Journal of radiation research

authors： Szuecs M,Kuhnt T,Punke C,Witt G,Klautke G,Kramp B,Hildebrandt G

更新日期：2015-01-01 00:00:00

abstract：:Neutron dose is transferred to biological materials through the recoil protons produced by elastic scattering. When a low-velocity proton collides with the atoms or molecules of a target, it changes to a hydrogen atom by electron capture; this hydrogen atom then changes to a proton by losing the electron. Because the ...

journal_title：Journal of radiation research

authors： Endo S

更新日期：2004-09-01 00:00:00

abstract：:Cytogenetic investigation of stable-type aberrations (translocations) was carried out with our improved methods on 28 elderly individuals in a high-background radiation area (HBRA) in China, and on 24 elderly individuals in a control area (CA). The level of radiation in HBRA is 3 to 5 times higher than in CA. The mean...

journal_title：Journal of radiation research

authors： Zhang W,Wang C,Chen D,Minamihisamatsu M,Morishima H,Yuan Y,Wei L,Sugahara T,Hayata I

更新日期：2004-09-01 00:00:00

abstract：:The physico-chemical form in which plutonium enters the body influences the lung distribution and the transfer rate from lungs to blood. In the present study, we evaluated the early lung damage and macrophage activation after pulmonary contamination of plutonium of various preparation modes which produce different sol...

journal_title：Journal of radiation research

authors： Van der Meeren A,Gremy O,Renault D,Miroux A,Bruel S,Griffiths N,Tourdes F

更新日期：2012-01-01 00:00:00

abstract：:In vivo laboratory experiments on tritium gas (HT) fixation in pine trees were conducted using one-way circuit inhalation apparatus and dwarf pine trees. After 2 hours of exposure to HT, tritium distribution in pine needles, branches, trunk, roots and soil was measured. The specific activity of tritium in pine needles...

journal_title：Journal of radiation research

authors： Ichimasa M,Ichimasa Y,Akita Y

更新日期：1989-12-01 00:00:00

abstract：:The effect of gamma-irradiation on a major nutritional function of the yolk sac (the uptake and digestion of macromolecular materials) was studied in rat visceral yolk sacs cultured in vitro being used 125I-labeled bovine serum albumin (RISA) as the tracer protein. The uptake of RISA (per g wet weight) by rat yolk sac...

journal_title：Journal of radiation research

authors： Takahashi S,Koshimoto C,Kubota Y

更新日期：1993-06-01 00:00:00

abstract：:miR-34a is transcriptionally induced by the tumor suppressor gene p53, which is often downregulated in non-small cell lung cancer (NSCLC). To address whether the downstream signal of miR-34a is sufficient to induce apoptosis and to alter cellular radiosensitivity, a chemical synthetic miR-34a mimic was delivered into ...

journal_title：Journal of radiation research

authors： Duan W,Xu Y,Dong Y,Cao L,Tong J,Zhou X

更新日期：2013-07-01 00:00:00

abstract：:Numerous attempts have been made to estimate the distance at which 50% of the individuals exposed to the A-bombing of Hiroshima and Nagasaki died, ostensibly from their exposure to ionizing radiation. It is difficult to convert most of these distance estimates to a dose-related LD50, since radiation shielding was igno...

journal_title：Journal of radiation research

authors： Fujita S,Kato H,Schull WJ

更新日期：1991-03-01 00:00:00

abstract：:The present paper reports and discusses the results concerning both the inter- and intrafraction accuracy achievable combining the immobilization system employed in patients with head-and-neck, brain and skull base tumors with image guidance at our particle therapy center. Moreover, we investigated the influence of in...

journal_title：Journal of radiation research

authors： Amelio D,Winter M,Habermehl D,Jäkel O,Debus J,Combs SE

更新日期：2013-07-01 00:00:00

abstract：:The purpose of this study was to quantify the changes of tumor blood flow (BF) in cervical cancer after radiation therapy by using perfusion computed tomography (CT), and to examine the difference between maximum slope (MS) and single-input one-compartment model (SOCM) methods. Fourteen consecutive patients who receiv...

journal_title：Journal of radiation research

authors： Shibuya K,Tsushima Y,Horisoko E,Noda SE,Taketomi-Takahashi A,Ohno T,Amanuma M,Endo K,Nakano T

更新日期：2011-01-01 00:00:00

abstract：:The purpose of the present study was to develop a hybrid magnetic resonance/computed tomography (MR/CT)-compatible phantom and tissue-equivalent materials for each MR and CT image. Therefore, the essential requirements necessary for the development of a hybrid MR/CT-compatible phantom were determined and the developme...

journal_title：Journal of radiation research

authors： Kim MJ,Lee SR,Song KH,Baek HM,Choe BY,Suh TS

更新日期：2020-03-23 00:00:00

abstract：:A photoluminescence glass dosimeter, GD-301, was applied to the measurement of low absorbed doses in mice exposed to low-dose rate 137Cs gamma-rays. The dosimeter system consists of small rod-shaped glass chip detectors capable of embedded in the body of a mouse and an automatic readout device equipped with a standard...

journal_title：Journal of radiation research

authors： Hoshi Y,Nomura T,Oda T,Iwasaki T,Fujita K,Ishikawa T,Kato A,Ikegami T,Sakai K,Tanooka H,Yamada T

更新日期：2000-06-01 00:00:00

abstract：:The International Space Environment Service (ISES) is an international organization for space weather forecasts and belongs to the International Union of Radio Science (URSI). There are eleven ISES forecast centers in the world, and Communications Research Laboratory (CRL) runs the Japanese one. We make forecasts on t...

journal_title：Journal of radiation research

authors： Watari S,Tomita F

更新日期：2002-12-01 00:00:00

abstract：:Our purpose was to develop recommendations for contouring the computed tomography (CT)-based high-risk clinical target volume (CTVHR) for 3D image-guided brachytherapy (3D-IGBT) for cervical cancer. A 15-member Japanese Radiation Oncology Study Group (JROSG) committee with expertise in gynecological radiation oncology...

journal_title：Journal of radiation research

authors： Ohno T,Wakatsuki M,Toita T,Kaneyasu Y,Yoshida K,Kato S,Ii N,Tokumaru S,Ikushima H,Uno T,Noda SE,Kazumoto T,Harima Y,The Working Group of the Gynecological Tumor Committee of the Japanese Radiation Oncology Study Group (JROSG).

更新日期：2017-05-01 00:00:00

abstract：:The purpose of this multi-institutional Phase II trial study was to prospectively investigate the efficacy of the herbal medicine TJ-14 for acute radiation-induced enteritis (ARE). TJ-14 was administered orally as a first-line treatment for ARE. The primary end point was efficacy at 1 week. The secondary end points we...

journal_title：Journal of radiation research

authors： Murai T,Matsuo M,Tanaka H,Manabe Y,Takaoka T,Hachiya K,Yamaguchi T,Otsuka S,Shibamoto Y

更新日期：2020-01-23 00:00:00

abstract：:This study aimed to evaluate the relationship between cardiac toxicity after definitive chemoradiotherapy (CRT) for esophageal cancer and the dose-volume histogram (DVH) of organs at risk (OARs) [using biological effective dose (BED)]. We analyzed the data of 83 patients with esophageal cancer treated using definitive...

journal_title：Journal of radiation research

authors： Takeuchi Y,Murakami Y,Kameoka T,Ochi M,Imano N,Takahashi I,Nishibuchi I,Kimura T,Kawahara D,Saito A,Nagata Y

更新日期：2020-03-23 00:00:00

abstract：:New precision radiotherapy (RT) techniques reduce the uncertainties in localizing soft and moving tumors. However, there are still many uncontrollable internal organ movements. In our study, patients who underwent neoadjuvant chemoradiotherapy (NA-CRT) for rectal cancer were evaluated to determine inter-fraction mesor...

journal_title：Journal of radiation research

authors： Alickikus ZA,Kuru A,Aydin B,Akcay D,Gorken IB

更新日期：2020-03-23 00:00:00

abstract：:The multifraction regimens commonly used in conventional clinical radiotherapy are largely based on radiobiological experiments. However, no experimental reports on skin reactions focusing on inter-strain differences have displayed clinical relevance to the fractionated dose schedule. In this study, mice of inbred str...

journal_title：Journal of radiation research

authors： Ohta T,Iwakawa M,Oohira C,Noda S,Minfu Y,Goto M,Tanaka H,Harada Y,Imai T

更新日期：2004-12-01 00:00:00

abstract：:Female C3H strain mice, which do not spontaneously exhibit frequent bone tumors and myeloid leukemias, were injected intraperitoneally with various doses of 10 to 12,000 Bq/animal of monomeric 239Pu citrate to clarify lifetime carcinogenesis caused by alpha-particles distributed mainly in the skeleton. Survival time w...

journal_title：Journal of radiation research

authors： Oghiso Y,Yamada Y,Iida H

更新日期：1997-06-01 00:00:00

abstract：:The purpose of this study was to analyze the dosimetry and investigate the clinical outcomes of radiation-induced rib fractures (RIRFs) after stereotactic body radiotherapy (SBRT). A total of 126 patients with Stage I primary lung cancer treated with SBRT, who had undergone follow-up computed tomography (CT) at least ...

journal_title：Journal of radiation research

authors： Miura H,Inoue T,Shiomi H,Oh RJ

更新日期：2015-03-01 00:00:00

abstract：:The purpose of this study was to evaluate interfractional changes of the minimum dose delivered to 90% of the high-risk clinical target volume (HR-CTV D90) and D2cc of the bladder and rectum during brachytherapy for uterine cervical cancer patients. A total of 52 patients received external beam radiotherapy and high-d...

journal_title：Journal of radiation research

authors： Ohkubo Y,Ohno T,Noda SE,Kubo N,Nakagawa A,Kawahara M,Abe T,Kiyohara H,Wakatsuki M,Nakano T

更新日期：2013-11-01 00:00:00

abstract：:The space radiation environment imposes increased dangers of exposure to ionizing radiation, particularly during a solar particle event (SPE). These events consist primarily of low energy protons that produce a highly inhomogeneous dose distribution. Due to this inherent dose heterogeneity, experiments designed to inv...

journal_title：Journal of radiation research

authors： Diffenderfer ES,Dolney D,Schaettler M,Sanzari JK,McDonough J,Cengel KA

更新日期：2014-03-01 00:00:00

abstract：:In this report we update our long-term follow-up results of the prospective study whose aim was to evaluate the efficacy of high-dose-rate (HDR) brachytherapy in combination with external-beam radiotherapy (EBRT) in the treatment of medically inoperable endometrial cancer. Between 1995 and 1998, 29 patients with stage...

journal_title：Journal of radiation research

authors： Inciura A,Atkocius V,Juozaityte E,Vaitkiene D

更新日期：2010-01-01 00:00:00

abstract：:Centrosomes function in proper cell division in animal cells. The centrosome consists of a pair of centrioles and the surrounding pericentriolar matrix (PCM). After cytokinesis, daughter cells each acquire one centrosome, which subsequently duplicates at the G1/S phase in a manner that is dependent upon CDK2/cyclin-E ...

journal_title：Journal of radiation research

authors： Shimada M,Komatsu K

更新日期：2009-07-01 00:00:00