Interfractional change of high-risk CTV D90 during image-guided brachytherapy for uterine cervical cancer.

abstract：:The aim of this research was to provide data from a single-center study of the treatment of synchronous hypopharyngeal cancer (HPC) and esophageal cancer (EC) with different treatment modalities. A total of 61 patients with synchronous HPC and EC were included in this study. Patients were treated with radiotherapy/che...

journal_title：Journal of radiation research

authors： Yang S,Yang S,Liao W,Huang R,Li B,Lu S,Li C,Wang Z,Li C,Pei J,Wen H,Zhang S

更新日期：2019-10-23 00:00:00

abstract：:Development of a curative local treatment for large hepatocellular carcinoma (HCC) is an important issue. Here, we investigated the dose homogeneity, safety and antitumor effectiveness of proton beam therapy (PBT) using a patch-field technique for large HCC. Data from nine patients (aged 52-79 years) with large HCC tr...

journal_title：Journal of radiation research

authors： Nakamura M,Fukumitsu N,Kamizawa S,Numajiri H,Nemoto Murofushi K,Ohnishi K,Aihara T,Ishikawa H,Okumura T,Tsuboi K,Sakurai H

更新日期：2018-09-01 00:00:00

abstract：:The aim of the study was to investigate the various effects of high linear energy transfer (LET) carbon ion (12C6+) and low LET X-ray radiation on MDA-MB-231 and MCF-7 human breast cancer cells and to explore the underlying mechanisms of radiation sensitivity. Cell proliferation, cell colony formation, cell cycle dist...

journal_title：Journal of radiation research

authors： Zhang Q,Kong Y,Yang Z,Liu Y,Liu R,Geng Y,Luo H,Zhang H,Li H,Feng S,Wang X

更新日期：2020-05-22 00:00:00

abstract：:The fertility span between the first and the last estrus was compared among female Chinese hamsters exposed to 1 Gy X-rays on neonatal day 0, 2, 4, 6, 8, 10 and 14. The fertility span changed dramatically according to the age at the time of irradiation. The females irradiated on day 4, 6 and 8 showed a definite delay ...

journal_title：Journal of radiation research

authors： Tateno H,Mikamo K

更新日期：1989-06-01 00:00:00

abstract：:This study proposes a quality assurance (QA) method incorporating radiobiological factors based on the QUANTEC-determined tumor control probability and the normal tissue complication probability (NTCP) of head-and-neck intensity-modulated radiation therapy (HN-IMRT). Per-beam measurements were conducted for 20 cases u...

journal_title：Journal of radiation research

authors： Hamatani N,Sumida I,Takahashi Y,Oda M,Seo Y,Isohashi F,Tamari K,Ogawa K

更新日期：2017-09-01 00:00:00

abstract：:Reactive oxygen species continuously oxidize DNA bases and threaten the genetic integrity. Thymine glycol (TG), one of the representative oxidized products, is repaired mainly by base excision repair (BER). In Escherichia coli, endonuclease III (Nth) and endonuclease VIII (Nei) are known to actively remove TG from DNA...

journal_title：Journal of radiation research

authors： Yamamoto R,Akiyama M,Ide H,Yamamoto K,Matsuyama S,Kubo K

更新日期：2008-05-01 00:00:00

abstract：:Carbon-ion therapy by layer-stacking irradiation for static targets has been practised in clinical treatments. In order to apply this technique to a moving target, disturbances of carbon-ion dose distributions due to respiratory motion have been studied based on the measurement using a respiratory motion phantom, and ...

journal_title：Journal of radiation research

authors： Tajiri S,Tashiro M,Mizukami T,Tsukishima C,Torikoshi M,Kanai T

更新日期：2017-11-01 00:00:00

abstract：:Although salvage external-beam radiation therapy (EBRT) is an attractive treatment option for pelvic lymph nodal recurrence (PeNR) in patients with prostate cancer (PCa), limited data are available regarding its long-term efficacy. This study examined the long-term clinical outcomes of patients who underwent salvage p...

journal_title：Journal of radiation research

authors： Sato GE,Aizawa R,Nakamura K,Takayama K,Inoue T,Yamasaki T,Kobayashi T,Akamatsu S,Ogawa O,Mizowaki T

更新日期：2020-07-06 00:00:00

abstract：:The purpose of this study was to quantify the changes of tumor blood flow (BF) in cervical cancer after radiation therapy by using perfusion computed tomography (CT), and to examine the difference between maximum slope (MS) and single-input one-compartment model (SOCM) methods. Fourteen consecutive patients who receiv...

journal_title：Journal of radiation research

authors： Shibuya K,Tsushima Y,Horisoko E,Noda SE,Taketomi-Takahashi A,Ohno T,Amanuma M,Endo K,Nakano T

更新日期：2011-01-01 00:00:00

abstract：:Cytogenetic investigation of stable-type aberrations (translocations) was carried out with our improved methods on 28 elderly individuals in a high-background radiation area (HBRA) in China, and on 24 elderly individuals in a control area (CA). The level of radiation in HBRA is 3 to 5 times higher than in CA. The mean...

journal_title：Journal of radiation research

authors： Zhang W,Wang C,Chen D,Minamihisamatsu M,Morishima H,Yuan Y,Wei L,Sugahara T,Hayata I

更新日期：2004-09-01 00:00:00

abstract：:To evaluate the effect of the sympathetic nervous system on radiation-induced apoptosis in jejunal crypt cells, apoptosis levels were compared in spontaneously hypertensive rats (SHR), animals which are a genetic hyperfunction model of the sympathetic nervous system, and normotensive Wistar-Kyoto rats (WKY). SHR and W...

journal_title：Journal of radiation research

authors： Matsuu M,Shichijo K,Nakamura Y,Ikeda Y,Naito S,Ito M,Okaichi K,Sekine I

更新日期：2000-03-01 00:00:00

abstract：:The quality of the sublethal damage (SLD) after irradiation with high-linear energy transfer (LET) ion beams was investigated with low-LET photons. Chinese hamster V79 cells and human squamous carcinoma SAS cells were first exposed to a priming dose of different ion beams at different LETs at the Heavy Ion Medical Acc...

journal_title：Journal of radiation research

authors： Furusawa Y,Nakano-Aoki M,Matsumoto Y,Hirayama R,Kobayashi A,Konishi T

更新日期：2017-11-01 00:00:00

abstract：:The purpose of this multi-institutional Phase II trial study was to prospectively investigate the efficacy of the herbal medicine TJ-14 for acute radiation-induced enteritis (ARE). TJ-14 was administered orally as a first-line treatment for ARE. The primary end point was efficacy at 1 week. The secondary end points we...

journal_title：Journal of radiation research

authors： Murai T,Matsuo M,Tanaka H,Manabe Y,Takaoka T,Hachiya K,Yamaguchi T,Otsuka S,Shibamoto Y

更新日期：2020-01-23 00:00:00

abstract：:Gated radiation therapy is a promising method for improving the dose conformality of treatments to moving targets and reducing the total volume of irradiated tissue. Target motion is of particular concern in proton beam radiotherapy, due to the finite range of proton dose deposition in tissue. Gating allows one to red...

journal_title：Journal of radiation research

authors： Sharp GC,Lu HM,Trofimov A,Tang X,Jiang SB,Turcotte J,Gierga DP,Chen GT,Hong TS

更新日期：2007-01-01 00:00:00

abstract：:The aim of this study was to carry out geometric and dosimetric evaluation of the usefulness of a deformable image registration algorithm utilized for adaptive head-and-neck intensity-modulated radiotherapy. Data consisted of seven patients, each with a planning CT (pCT), a rescanning CT (ReCT) and a cone beam CT (CBC...

journal_title：Journal of radiation research

authors： Eiland RB,Maare C,Sjöström D,Samsøe E,Behrens CF

更新日期：2014-09-01 00:00:00

abstract：:Recently fluorescence in situ hybridization protocols have been developed which allow the painting of individual chromosomes using DNA-libraries from sorted human chromosomes. This approach has the particular advantage that radiation induced chromosome translocations can be easily detected, if chromosomes of distinctl...

journal_title：Journal of radiation research

authors： Popp S,Cremer T

更新日期：1992-03-01 00:00:00

abstract：:Patient A who was exposed to a critical dose of radiation developed skin lesions throughout the body surface, gastrointestinal disorder with massive diarrhea and prominent bleeding, which caused severe loss in body fluids. Gastrointestinal bleeding due to the deteriorated intestinal mucosa was considered to be one of ...

journal_title：Journal of radiation research

authors： Ishii T,Futami S,Nishida M,Suzuki T,Sakamoto T,Suzuki N,Maekawa K

更新日期：2001-09-01 00:00:00

abstract：:The purpose of this study was to evaluate the efficacy and toxicity of radiotherapy concurrently with weekly cisplatin, followed by adjuvant chemotherapy, for the treatment of N2-3 nasopharyngeal cancer (NPC) in Asian countries, especially regions of South and Southeast Asian countries where NPC is endemic. Between 20...

journal_title：Journal of radiation research

authors： Ohno T,Thinh DH,Kato S,Devi CR,Tung NT,Thephamongkhol K,Calaguas MJ,Zhou J,Chansilpa Y,Supriana N,Erawati D,Banu PA,Koo CC,Kobayashi K,Nakano T,Tsujii H

更新日期：2013-05-01 00:00:00

abstract：:To clarify the nature of the genes that contribute to the radiosensitivity of human hematopoietic stem/progenitor cells (HSPCs), we analyzed the gene expression profiles detected in HSPCs irradiated with 2 Gy X-rays after culture with or without an optimal combination of hematopoietic cytokines. Highly purified CD34(+...

journal_title：Journal of radiation research

authors： Tsujiguchi T,Hirouchi T,Monzen S,Tabuchi Y,Takasaki I,Kondo T,Kashiwakura I

更新日期：2016-01-01 00:00:00

abstract：:To determine the patterns of gene expression responsible for the radiosensitivity of glioblastoma cells, we analyzed transcriptional changes after ionizing radiation in different cell lines. After completing clonogenic survival assays, we selected two glioblastoma cell lines with different radiosensitivities. Subseque...

journal_title：Journal of radiation research

authors： Otomo T,Hishii M,Arai H,Sato K,Sasai K

更新日期：2004-03-01 00:00:00

abstract：:Respiratory motion management is a huge challenge in radiation therapy. Respiratory motion induces temporal anatomic changes that distort the tumor volume and its position. In this study, a markerless tumor-tracking algorithm was investigated by performing phase recognition during stereotactic body radiation therapy (...

journal_title：Journal of radiation research

authors： Bhusal Chhatkuli R,Demachi K,Uesaka M,Nakagawa K,Haga A

更新日期：2019-01-01 00:00:00

abstract：:Millimeter waves are used in various fields, and the risks of this wavelength range for human health must be carefully evaluated. In this study, we investigated the effects of millimeter waves on genotoxicity and heat shock protein expression in human corneal epithelial (HCE-T) and human lens epithelial (SRA01/04) cel...

journal_title：Journal of radiation research

authors： Koyama S,Narita E,Suzuki Y,Shiina T,Taki M,Shinohara N,Miyakoshi J

更新日期：2019-07-01 00:00:00

abstract：:Reassessment of gamma-ray doses from the atomic bombs in Hiroshima and Nagasaki has been carried out with the thermoluminescent measurements of bricks and decorative tiles which were collected from the buildings that remain as they were at the time of the explosions. The thermoluminescent measurements were performed u...

journal_title：Journal of radiation research

authors： Maruyama T,Kumamoto Y,Noda Y

更新日期：1991-03-01 00:00:00

abstract：:In this study, a mechanism in which low-dose hyper-radiosensitivity (HRS) is permanently removed, induced by low-dose-rate (LDR) (0.2-0.3 Gy/h for 1 h) but not by high-dose-rate priming (0.3 Gy at 40 Gy/h) was investigated. One HRS-negative cell line (NHIK 3025) and two HRS-positive cell lines (T-47D, T98G) were used....

journal_title：Journal of radiation research

authors： Edin NJ,Sandvik JA,Vollan HS,Reger K,Görlach A,Pettersen EO

更新日期：2013-11-01 00:00:00

abstract：:The Rho-associated coiled-coil-containing protein kinase (ROCK) pathway is known to influence metastasis in several cancers; however, the impact of the pathway on clinical outcomes in patients undergoing radiotherapy remains unknown. In the present study, the expression of RhoA, RhoC, ROCK-1, ROCK-2 and p53 was immuno...

journal_title：Journal of radiation research

authors： Tanaka K,Matsumoto Y,Ishikawa H,Fukumitsu N,Numajiri H,Murofushi K,Oshiro Y,Okumura T,Satoh T,Sakurai H

更新日期：2020-03-23 00:00:00

abstract：:Boron Neutron Capture Therapy (BNCT) effectiveness depends on the preferential sequestration of boron in cancer cells relative to normal tissue cells. We present a novel strategy for sequestering boron using an adenovirus expressing the sodium iodide symporter (NIS). Human glioma grown subcutaneously in athymic mice a...

journal_title：Journal of radiation research

authors： Kumar S,Freytag SO,Barton KN,Burmeister J,Joiner MC,Sedghi B,Movsas B,Binns PJ,Kim JH,Brown SL

更新日期：2010-01-01 00:00:00

abstract：:When DNA is damaged by exposure to a small amount of radiation, it is repaired efficiently by innate mechanisms. However, if cellular damage is more extensive, DNA repair cannot be adequately completed. To clarify the role of the p53 gene in apoptotic tissue repair, the incidence of in-vivo radiation-induced somatic m...

journal_title：Journal of radiation research

authors： Kato F,Kakihara H,Kunugita N,Ootsuyama A,Norimura T

更新日期：2002-12-01 00:00:00

abstract：:Before the sorafenib era, advanced but liver-confined hepatocellular carcinoma (HCC) was treated by liver-directed therapy. Hepatic arterial concurrent chemoradiotherapy (CCRT) has been performed in our group, giving substantial local control but frequent failure. The aim of this study was to analyze patterns of failu...

journal_title：Journal of radiation research

authors： Cha H,Yoon HI,Lee IJ,Koom WS,Han KH,Seong J

更新日期：2013-11-01 00:00:00

abstract：:In case of an accidental overexposure to ionizing radiation where the dose received by the victim is over 5 Gy, the conventional biological indicator of dose, the dicentric assay, does not provide an accurate enough dose measurement. A more appropriate technique is to measure ring chromosomes in stimulated lymphocytes...

journal_title：Journal of radiation research

authors： Lamadrid AI,García O,Delbos M,Voisin P,Roy L

更新日期：2007-01-01 00:00:00

abstract：:We have proposed four dimensional (4D) digitally reconstructed radiography (DRR) for verifying a lung tumor position during volumetric modulated arc therapy (VMAT). An internal target volume (ITV) was defined based on two clinical target volumes (CTVs) delineated on maximum exhalation and maximum inhalation images acq...

journal_title：Journal of radiation research

authors： Nakagawa K,Kida S,Haga A,Masutani Y,Yamashita H,Onoe T,Imae T,Tanaka K,Ohtomo K,Yoda K

更新日期：2012-07-01 00:00:00