Expression analysis of radiation-responsive genes in human hematopoietic stem/progenitor cells.

abstract：:We investigated the efficacy and safety of albumin-bound paclitaxel (nab-PTX) and carboplatin (CBDCA) with concurrent radiotherapy for unresectable locally advanced non-small-cell lung cancer (NSCLC). Patients with Stage III NSCLC and an Eastern Cooperative Oncology Group performance status of 0 or 1 were eligible. Co...

journal_title：Journal of radiation research

authors： Hasegawa T,Futamura Y,Horiba A,Yoshida T,Suzuki T,Kato T,Kaito D,Ohno Y,Iida T,Hayashi S,Sawa T

更新日期：2016-01-01 00:00:00

abstract：:Synchrotron-radiation circular-dichroism spectroscopy was used to reveal that the DNA damage response induces a decrement of α-helix and an increment of β-strand contents of histone H3-H4 extracted from X-ray-irradiated human HeLa cells. The trend of the structural alteration was qualitatively opposite to that of our ...

journal_title：Journal of radiation research

authors： Izumi Y,Fujii K,Yamamoto S,Matsuo K,Namatame H,Taniguchi M,Yokoya A

更新日期：2017-01-01 00:00:00

abstract：:Cytogenetic investigation of stable-type aberrations (translocations) was carried out with our improved methods on 28 elderly individuals in a high-background radiation area (HBRA) in China, and on 24 elderly individuals in a control area (CA). The level of radiation in HBRA is 3 to 5 times higher than in CA. The mean...

journal_title：Journal of radiation research

authors： Zhang W,Wang C,Chen D,Minamihisamatsu M,Morishima H,Yuan Y,Wei L,Sugahara T,Hayata I

更新日期：2004-09-01 00:00:00

abstract：:This project aimed to set up a Beagle dog model of radiation-induced lung injury in order to supply fresh lung tissue samples in the different injury phases for gene and protein research. Three dogs received 18 Gy X-ray irradiation in one fraction, another three dogs received 8 Gy in each of three fractions at weekly ...

journal_title：Journal of radiation research

authors： Yin Z,Deng S,Liang Z,Wang Q

更新日期：2016-09-01 00:00:00

abstract：:The biokinetics of radon in the body has previously been studied with the assumption that its absorption through the skin is negligibly small. This assumption would be acceptable except in specific situations, such as bathing in a radon hot spring where the radon concentration in thermal water is far higher than that ...

journal_title：Journal of radiation research

authors： Sakoda A,Ishimori Y,Tschiersch J

更新日期：2016-07-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common progressive and irreversible neurodegenerative disease and it is caused by neuronal death in the brain. Recent studies have shown that non-ionizing radiofrequency (RF) radiation has some beneficial cognitive effects in animal models of AD. In this study, we examined the effe...

journal_title：Journal of radiation research

authors： Lee JS,Kim JY,Kim HJ,Kim JC,Lee JS,Kim N,Park MJ

更新日期：2016-11-01 00:00:00

abstract：:The health effects of radiation exposure from the atomic bomb fallout remain unclear. The objective of the present study is to elucidate the association between low-dose radiation exposure from the atomic bomb fallout and cancer mortality among Nagasaki atomic bomb survivors. Of 77 884 members in the Nagasaki Universi...

journal_title：Journal of radiation research

authors： Yokota K,Mine M,Kondo H,Matsuda N,Shibata Y,Takamura N

更新日期：2018-01-01 00:00:00

abstract：:The purpose of the study was to quantify local setup errors and evaluate the planning target volume (PTV) margins for sub-regions in cone-beam computed tomography (CBCT)-guided post-mastectomy radiation therapy (PMRT). The local setup errors of 20 patients undergoing CBCT-guided PMRT were analysed retrospectively. Ima...

journal_title：Journal of radiation research

authors： Zhou J,Li S,Ye C,Shen K,Li A,Chen G,Li X,Bai S,Wang W,Zhong R

更新日期：2020-05-22 00:00:00

abstract：:Due to the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident, the evacuees from Namie Town still cannot reside in the town, and some continue to live in temporary housing units. In this study, the radon activity concentrations were measured at temporary housing facilities, apartments and detached houses in Fukush...

journal_title：Journal of radiation research

authors： Hosoda M,Tokonami S,Omori Y,Ishikawa T,Iwaoka K

更新日期：2016-07-01 00:00:00

abstract：:The present paper is part of an attempt at finally reconstructing the realities of nuclear tests and their human effects near Semipalatinsk, Kazakhstan. As a first step, it tries to reconstruct the overall image of nuclear tests and their human effects. Our data are 199 written testimonies of those affected by radiati...

journal_title：Journal of radiation research

authors： Matsuo M,Kawano N,Satoh K,Apsalikov KN,Moldagaliev T

更新日期：2006-02-01 00:00:00

abstract：:The hypothesis that exposure to ionizing radiation accelerates the aging process has been actively investigated at ABCC-RERF since 1958, when longitudinal cohort studies of the Adult Health Study (AHS) and the Life Span Study (LSS) were initiated. In their 1975 overall review of aging studies related to the atomic bom...

journal_title：Journal of radiation research

authors： Sasaki H,Kodama K,Yamada M

更新日期：1991-03-01 00:00:00

abstract：:Efficacy of different schedules of HDR brachytherapy in concurrent chemoradiotherapy was evaluated. The study compared the effectiveness of the two HDR brachytherapy schedules which have the same Biological Effective Dose (BED) in locally advanced cervical carcinoma that was treated with concurrent chemoradiotherapy. ...

journal_title：Journal of radiation research

authors： Tharavichitkul E,Klunkin P,Lorvidhaya V,Sukthomya V,Chakrabhandu S,Pukanhaphan N,Chitapanarux I,Galalae R

更新日期：2012-01-01 00:00:00

abstract：:In this study, a mechanism in which low-dose hyper-radiosensitivity (HRS) is permanently removed, induced by low-dose-rate (LDR) (0.2-0.3 Gy/h for 1 h) but not by high-dose-rate priming (0.3 Gy at 40 Gy/h) was investigated. One HRS-negative cell line (NHIK 3025) and two HRS-positive cell lines (T-47D, T98G) were used....

journal_title：Journal of radiation research

authors： Edin NJ,Sandvik JA,Vollan HS,Reger K,Görlach A,Pettersen EO

更新日期：2013-11-01 00:00:00

abstract：:The aim of this study is to demonstrate the feasibility of estimating the strength of the moving radiation source during patient implantation. The requirement for the counting time was investigated by comparing the results of the measurements for the static source with those for the source moving at 2, 5, 10 and 20 cm...

journal_title：Journal of radiation research

authors： Tanaka K,Endo S,Tateoka K,Asanuma O,Kamo K,Sato K,Takeda H,Takagi M,Hareyama M,Takada J

更新日期：2014-01-01 00:00:00

abstract：:The aim of the study was to evaluate inter-fractional dosimetric variations for high-dose rate breast brachytherapy using a strut-adjusted volume implant (SAVI). For the nine patients included, dosimetric constraints for treatment were as follows: for the planning target volume for evaluation (PTV_Eval), the volume re...

journal_title：Journal of radiation research

authors： Iijima K,Okamoto H,Takahashi K,Aikawa A,Wakita A,Nakamura S,Nishioka S,Harada K,Notake R,Sugawara A,Yoshimura R,Kunieda E,Itami J

更新日期：2020-01-23 00:00:00

abstract：:In hypofractionated stereotactic radiotherapy (SRT), high doses per fraction are usually used and the dose delivery pattern is different from that of conventional radiation. The daily dose is usually given intermittently over a longer time compared with conventional radiotherapy. During prolonged radiation delivery, s...

journal_title：Journal of radiation research

authors： Shibamoto Y,Miyakawa A,Otsuka S,Iwata H

更新日期：2016-08-01 00:00:00

abstract：:Immediately after X-irradiation, monocytic cells can express the gene for interleukin (IL)-1beta, which enhances inflammation and contributes to radioprotection in mice. In order to analyze the mechanism(s) for the immediate-early induction of IL-1beta after X-irradiation at 20 Gy in cultured murine macrophages, we ex...

journal_title：Journal of radiation research

authors： Ishihara H,Tanaka I,Wan H,Cheeramakara C

更新日期：2003-06-01 00:00:00

abstract：:The pulse radiolysis technique has been employed to determine the initiation and propagation rates of different transient species involved in the polymerization of N-isopropylacrylamide (NIPA) in aqueous solutions. Polymerization by anionic mechanism has been observed to be faster than by the free-radical mechanism. T...

journal_title：Journal of radiation research

authors： Acharya A,Mohan H,Sabharwal S

更新日期：2003-12-01 00:00:00

abstract：:Recently fluorescence in situ hybridization protocols have been developed which allow the painting of individual chromosomes using DNA-libraries from sorted human chromosomes. This approach has the particular advantage that radiation induced chromosome translocations can be easily detected, if chromosomes of distinctl...

journal_title：Journal of radiation research

authors： Popp S,Cremer T

更新日期：1992-03-01 00:00:00

abstract：:To assess the mutational effects of radiation on vigorously proliferating plant tissue, the mutation spectrum was analyzed with Arabidopsis seedlings using the plasmid-rescue method. Transgenic plants containing the Escherichia coli rpsL gene were irradiated with γ-rays and carbon ion beams (320-MeV (12)C(6+)), and mu...

journal_title：Journal of radiation research

authors： Yoshihara R,Nozawa S,Hase Y,Narumi I,Hidema J,Sakamoto AN

更新日期：2013-11-01 00:00:00

abstract：:This study investigates whether in-room computed tomography (CT)-based adaptive treatment planning (ATP) is robust against interfractional location variations, namely, interfractional organ motions and/or applicator displacements, in 3D intracavitary brachytherapy (ICBT) for uterine cervical cancer. In ATP, the radiat...

journal_title：Journal of radiation research

authors： Oku Y,Arimura H,Nguyen TT,Hiraki Y,Toyota M,Saigo Y,Yoshiura T,Hirata H

更新日期：2016-11-01 00:00:00

abstract：:Previous studies have demonstrated that X-ray irradiation affects angiogenesis in tumors. Here, we studied the effects of gamma-ray irradiation on boron-10 compound accumulation in a murine tumor model. The mouse squamous cell carcinoma was irradiated with gamma-ray before BSH ((10)B-enriched borocaptate sodium) admin...

journal_title：Journal of radiation research

authors： Liu Y,Nagata K,Masunaga S,Suzuki M,Kashino G,Kinashi Y,Tanaka H,Sakurai Y,Maruhashi A,Ono K

更新日期：2009-11-01 00:00:00

abstract：:Liquid ionization chambers (LICs) are highly sensitive to dose irradiation and have small perturbations because of their liquid-filled sensitive volume. They require a sensitive volume much smaller than conventional air-filled chambers. However, it has been reported that the collection efficiency has dependencies on t...

journal_title：Journal of radiation research

authors： Takei H,Isobe T,Kitamura N,Mori Y,Tomita T,Kobayashi D,Kamizawa S,Sato T,Sakurai H,Sakae T

更新日期：2018-05-01 00:00:00

abstract：:In our previous studies, we found that low-dose radiation inhibits oxidative stress-induced diseases due to increased antioxidants. Although these effects of low-dose radiation were demonstrated, further research was needed to clarify the effects. However, the analysis of oxidative stress is challenging, especially th...

journal_title：Journal of radiation research

authors： Kanzaki N,Kataoka T,Etani R,Sasaoka K,Kanagawa A,Yamaoka K

更新日期：2017-01-01 00:00:00

abstract：:Halobacterium salinarium, a member of the extremely halophilic archaebacteria, contains a C50-carotenoid namely bacterioruberin. We have previously reported the high resistance of this organism against the lethal actions of DNA-damaging agents including ionizing radiation and ultraviolet light (UV). In this study, we ...

journal_title：Journal of radiation research

authors： Shahmohammadi HR,Asgarani E,Terato H,Saito T,Ohyama Y,Gekko K,Yamamoto O,Ide H

更新日期：1998-12-01 00:00:00

abstract：:In case of an accidental overexposure to ionizing radiation where the dose received by the victim is over 5 Gy, the conventional biological indicator of dose, the dicentric assay, does not provide an accurate enough dose measurement. A more appropriate technique is to measure ring chromosomes in stimulated lymphocytes...

journal_title：Journal of radiation research

authors： Lamadrid AI,García O,Delbos M,Voisin P,Roy L

更新日期：2007-01-01 00:00:00

abstract：:There is an urgent need to develop non-toxic radioprotectors. We tested the efficacy of a 3-drug combination (3-DC) of iloprost, misoprostol, and 3D-MPL (3-deacylated monophosphoryl lipid A) and the effects of postirradiation clinical support with high doses of antibiotics and blood transfusion. Canines were given 3-D...

journal_title：Journal of radiation research

authors： Kumar KS,Srinivasan V,Toles RE,Miner VL,Jackson WE,Seed TM

更新日期：2002-12-01 00:00:00

abstract：:The purpose of this review was to evaluate the impact of epidermal growth factor receptor (EGFR) mutation status on disease recurrence in patients treated with chemoradiotherapy (CRT) for locally advanced non-small cell lung cancer (NSCLC). A literature search was conducted and a total of three studies were analyzed. ...

journal_title：Journal of radiation research

authors： Ochiai S,Nomoto Y,Watanabe Y,Yamashita Y,Toyomasu Y,Kawamura T,Takada A,Noriko,Sakuma H

更新日期：2016-09-01 00:00:00

abstract：:As a part of technical improvements of chromosome aberration analysis on human peripheral lymphocytes for biological radiation dosimetry, we examined the optimal conditions for the use of colcemid in chromosome preparation in order to obtain enough number of cells at metaphase in the first cell division. When treated ...

journal_title：Journal of radiation research

authors： Kanda R,Jiang T,Hayata I,Kobayashi S

更新日期：1994-03-01 00:00:00

abstract：:We evaluated the radiological response and clinical outcome in patients with femoral bone metastases after radiotherapy. 102 consecutive patients with femoral metastases without pathological fracture were treated by surgery or radiotherapy between 2002 and 2005. Twelve of them initially treated with surgery were exclu...

journal_title：Journal of radiation research

authors： Harada H,Katagiri H,Kamata M,Yoshioka Y,Asakura H,Hashimoto T,Furutani K,Takahashi M,Sakahara H,Nishimura T

更新日期：2010-01-01 00:00:00