Disappearance of nuclear binding proteins specifically bound to the upstream region of the interleukin-1beta gene immediately after irradiation of mouse macrophages.

abstract：:Thyroid cells were given 5.5 Gy X-rays in situ and transplanted after 1 day or after 6 weeks to form colonies in fat pads. The colony-forming efficiency unexpectedly decreased by a factor of about 2 with this increase in delay time before transplantation. In addition, there was a concomitant marked increase above the ...

journal_title：Journal of radiation research

authors： Watanabe H,Hendry JH

更新日期：1994-06-01 00:00:00

abstract：:We investigated the efficacy and safety of albumin-bound paclitaxel (nab-PTX) and carboplatin (CBDCA) with concurrent radiotherapy for unresectable locally advanced non-small-cell lung cancer (NSCLC). Patients with Stage III NSCLC and an Eastern Cooperative Oncology Group performance status of 0 or 1 were eligible. Co...

journal_title：Journal of radiation research

authors： Hasegawa T,Futamura Y,Horiba A,Yoshida T,Suzuki T,Kato T,Kaito D,Ohno Y,Iida T,Hayashi S,Sawa T

更新日期：2016-01-01 00:00:00

abstract：:The multifraction regimens commonly used in conventional clinical radiotherapy are largely based on radiobiological experiments. However, no experimental reports on skin reactions focusing on inter-strain differences have displayed clinical relevance to the fractionated dose schedule. In this study, mice of inbred str...

journal_title：Journal of radiation research

authors： Ohta T,Iwakawa M,Oohira C,Noda S,Minfu Y,Goto M,Tanaka H,Harada Y,Imai T

更新日期：2004-12-01 00:00:00

abstract：:Male C3H/HeN mice were exposed to 252Cf radiation and mated with unirradiated C57BL/6N females. F1 mice were analyzed for germline mutation at the paternally derived C3H/HeN allele of a hypervariable minisatellite locus, Ms6hm. This locus exhibited a high frequency of length change mutation spontaneously, and the muta...

journal_title：Journal of radiation research

authors： Niwa O,Fan YJ,Numoto M,Kamiya K,Kominami R

更新日期：1996-09-01 00:00:00

abstract：:To understand the biological response of normal cells to fractionated carbon beam irradiation, the effects of potentially lethal damage repair (PLDR) and sublethal damage repair (SLDR) were both taken into account in a linear-quadratic (LQ) model. The model was verified by the results of a fractionated cell survival e...

journal_title：Journal of radiation research

authors： Wada M,Suzuki M,Liu C,Kaneko Y,Fukuda S,Ando K,Matsufuji N

更新日期：2013-09-01 00:00:00

abstract：:Perirectal hyaluronate gel injection (HGI) appears to be a promising technique for healthy tissue dose sparing in pelvic radiotherapy. In this analysis, we report our initial experience of HGI in gynecologic brachytherapy, focusing on its safety and effectiveness for dose reduction to the rectum. Between July 2013 and...

journal_title：Journal of radiation research

authors： Kashihara T,Murakami N,Tselis N,Kobayashi K,Tsuchida K,Shima S,Masui K,Yoshida K,Takahashi K,Inaba K,Umezawa R,Igaki H,Ito Y,Kato T,Uno T,Itami J

更新日期：2019-07-01 00:00:00

abstract：:There is an urgent need to develop non-toxic radioprotectors. We tested the efficacy of a 3-drug combination (3-DC) of iloprost, misoprostol, and 3D-MPL (3-deacylated monophosphoryl lipid A) and the effects of postirradiation clinical support with high doses of antibiotics and blood transfusion. Canines were given 3-D...

journal_title：Journal of radiation research

authors： Kumar KS,Srinivasan V,Toles RE,Miner VL,Jackson WE,Seed TM

更新日期：2002-12-01 00:00:00

abstract：:Our purpose was to develop recommendations for contouring the computed tomography (CT)-based high-risk clinical target volume (CTVHR) for 3D image-guided brachytherapy (3D-IGBT) for cervical cancer. A 15-member Japanese Radiation Oncology Study Group (JROSG) committee with expertise in gynecological radiation oncology...

journal_title：Journal of radiation research

authors： Ohno T,Wakatsuki M,Toita T,Kaneyasu Y,Yoshida K,Kato S,Ii N,Tokumaru S,Ikushima H,Uno T,Noda SE,Kazumoto T,Harima Y,The Working Group of the Gynecological Tumor Committee of the Japanese Radiation Oncology Study Group (JROSG).

更新日期：2017-05-01 00:00:00

abstract：:In this study, a mechanism in which low-dose hyper-radiosensitivity (HRS) is permanently removed, induced by low-dose-rate (LDR) (0.2-0.3 Gy/h for 1 h) but not by high-dose-rate priming (0.3 Gy at 40 Gy/h) was investigated. One HRS-negative cell line (NHIK 3025) and two HRS-positive cell lines (T-47D, T98G) were used....

journal_title：Journal of radiation research

authors： Edin NJ,Sandvik JA,Vollan HS,Reger K,Görlach A,Pettersen EO

更新日期：2013-11-01 00:00:00

abstract：:We propose a clinical workflow of stereotactic volumetric modulated arc therapy (VMAT) for a lung tumor from planning to tumor position verification using 4D planning computed tomography (CT) and 4D cone-beam CT (CBCT). A 4D CT scanner, an Anzai belt and a BodyFix were employed to obtain 10-phase respiratory-correlate...

journal_title：Journal of radiation research

authors： Nakagawa K,Haga A,Kida S,Masutani Y,Yamashita H,Takahashi W,Sakumi A,Saotome N,Shiraki T,Ohtomo K,Iwai Y,Yoda K

更新日期：2013-01-01 00:00:00

abstract：:Ionizing radiation induces biological effects not only in irradiated cells but also in non-irradiated cells, which is called the bystander effect. Recently, in vivo and in vitro experiments have suggested that both gap junction hemichannel connexin43 (Cx43) and extracellular adenosine triphosphate (ATP) released from ...

journal_title：Journal of radiation research

authors： Ohshima Y,Tsukimoto M,Harada H,Kojima S

更新日期：2012-07-01 00:00:00

abstract：:Radiation therapy (RT) has become particularly important recently for treatment of liver tumors, but there are few experimental investigations pertaining to radiation-induced liver injuries over long-term follow-up periods. Thus, the present study examined pathological liver features over a 10-month period using an in...

journal_title：Journal of radiation research

authors： Imaeda M,Ishikawa H,Yoshida Y,Takahashi T,Ohkubo Y,Musha A,Komachi M,Nakazato Y,Nakano T

更新日期：2014-07-01 00:00:00

abstract：:To evaluate the present levels of 239,240Pu and U in residents living near the Semipalatinsk nuclear test site, more than 70 bone samples were obtained at autopsy. The subjects ranged in age from 30 to 86 years (mean 59.3+/-12.9). Most of the samples consisted of victims who died of various diseases. Plutonium and U w...

journal_title：Journal of radiation research

authors： Yamamoto M,Hoshi M,Sakaguchi A,Shinohara K,Kurihara O,Apsalikov KN,Gusev BI

更新日期：2006-02-01 00:00:00

abstract：:Due to the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident, the evacuees from Namie Town still cannot reside in the town, and some continue to live in temporary housing units. In this study, the radon activity concentrations were measured at temporary housing facilities, apartments and detached houses in Fukush...

journal_title：Journal of radiation research

authors： Hosoda M,Tokonami S,Omori Y,Ishikawa T,Iwaoka K

更新日期：2016-07-01 00:00:00

abstract：:X-ray induced formation of micronuclei is generally thought to result from DNA double-strand breaks (DSBs). However, DNA DSBs inhibit the cell cycle progression that is required for micronucleus formation. In order to reconcile this apparent discrepancy, we investigated whether DNA DSBs induced during the G1 phase cou...

journal_title：Journal of radiation research

authors： Okada T,Kashino G,Nishiura H,Tano K,Watanabe M

更新日期：2012-01-01 00:00:00

abstract：:As a part of technical improvements of chromosome aberration analysis on human peripheral lymphocytes for biological radiation dosimetry, we examined the optimal conditions for the use of colcemid in chromosome preparation in order to obtain enough number of cells at metaphase in the first cell division. When treated ...

journal_title：Journal of radiation research

authors： Kanda R,Jiang T,Hayata I,Kobayashi S

更新日期：1994-03-01 00:00:00

abstract：:While recent advances in elucidating the enzyme/substrate relationship of phosphorylation cascades have demonstrated several distinct pathways in membrane-cytoplasm signaling, the molecular dissection of p53 and the products of other proto-oncogenes have greatly promoted the studies of nuclear signaling and expanded t...

journal_title：Journal of radiation research

authors： Wang X,Ohnishi T

更新日期：1997-09-01 00:00:00

abstract：:A synergistic interaction of hyperthermia with ionizing or UV light (254 nm) radiation was analyzed in experiments with yeast cells. For a fixed dose rate of radiation, the synergism was shown to be observed only within a definite temperature range (40-45 degrees C), inside of which there was an optimal temperature to...

journal_title：Journal of radiation research

authors： Kim JK,Petin VG,Zhurakovskaya GP

更新日期：2001-12-01 00:00:00

abstract：:Tritium precipitations in European cities and in Osaka, Japan were analyzed before and after the Chernobyl nuclear plant accident by the time series analysis code Census IIX11 developed by US Department of Commerce Bureau of the Census. Results of this analysis showed no significant tritium precipitation was produced ...

journal_title：Journal of radiation research

authors： Koga T,Morishima H,Niwa T,Kawai H

更新日期：1991-09-01 00:00:00

abstract：:To investigate the importance of gender and aging on the individual radiosensitivity of lineage-committed myeloid hematopoietic stem/progenitor cells (HSPCs) detected in mononuclear cells (MNCs) of steady-state human peripheral blood (PB), the clonogenic survival of HPCs, including colony-forming unit-granulocyte macr...

journal_title：Journal of radiation research

authors： Kato K,Kuwabara M,Kashiwakura I

更新日期：2011-01-01 00:00:00

abstract：:We previously showed that free radicals and oxidative stress are involved in radiation-induced skin reactions. Since vitamin E (VE) is a particularly important lipophilic antioxidant, VE-deficient mice were used to examine its effects on radiation-induced skin damage. The VE content of the skin was reduced to one four...

journal_title：Journal of radiation research

authors： Chi C,Hayashi D,Nemoto M,Nyui M,Urano S,Anzai K

更新日期：2011-01-01 00:00:00

abstract：:We have proposed four dimensional (4D) digitally reconstructed radiography (DRR) for verifying a lung tumor position during volumetric modulated arc therapy (VMAT). An internal target volume (ITV) was defined based on two clinical target volumes (CTVs) delineated on maximum exhalation and maximum inhalation images acq...

journal_title：Journal of radiation research

authors： Nakagawa K,Kida S,Haga A,Masutani Y,Yamashita H,Onoe T,Imae T,Tanaka K,Ohtomo K,Yoda K

更新日期：2012-07-01 00:00:00

abstract：:We examined the use of the mouse Pc-3 ESTR (expanded simple tandem repeat) locus and 72 human microsatellite loci as potentially sensitive biomarkers for mutagenic exposures to germ cells in mice and humans respectively. In the mouse work, we treated male mice with TCDD (2, 3, 7, 8-tetrachlorodibenzo-p-dioxin; a chemi...

journal_title：Journal of radiation research

authors： Ryo H,Nakajima H,Nomura T

更新日期：2006-01-01 00:00:00

abstract：:The effect of gamma-irradiation on a major nutritional function of the yolk sac (the uptake and digestion of macromolecular materials) was studied in rat visceral yolk sacs cultured in vitro being used 125I-labeled bovine serum albumin (RISA) as the tracer protein. The uptake of RISA (per g wet weight) by rat yolk sac...

journal_title：Journal of radiation research

authors： Takahashi S,Koshimoto C,Kubota Y

更新日期：1993-06-01 00:00:00

abstract：:Low doses (2.5-15 cGy) of X-irradiation two months prior to a second exposure to a sublethal dose enhanced the survival rate in mice. Optimal and significant increase was observed with 5-10 cGy. Endogenous spleen colony counts (endo-CFUs) after 7 Gy increased by a factor of about 1.7 in mice pre-irradiated with 5-10 c...

journal_title：Journal of radiation research

authors： Yonezawa M,Takeda A,Misonoh J

更新日期：1990-09-01 00:00:00

abstract：:Halobacterium salinarium, a member of the extremely halophilic archaebacteria, contains a C50-carotenoid namely bacterioruberin. We have previously reported the high resistance of this organism against the lethal actions of DNA-damaging agents including ionizing radiation and ultraviolet light (UV). In this study, we ...

journal_title：Journal of radiation research

authors： Shahmohammadi HR,Asgarani E,Terato H,Saito T,Ohyama Y,Gekko K,Yamamoto O,Ide H

更新日期：1998-12-01 00:00:00

abstract：:Cytogenetic investigation of stable-type aberrations (translocations) was carried out with our improved methods on 28 elderly individuals in a high-background radiation area (HBRA) in China, and on 24 elderly individuals in a control area (CA). The level of radiation in HBRA is 3 to 5 times higher than in CA. The mean...

journal_title：Journal of radiation research

authors： Zhang W,Wang C,Chen D,Minamihisamatsu M,Morishima H,Yuan Y,Wei L,Sugahara T,Hayata I

更新日期：2004-09-01 00:00:00

abstract：:The purpose of this study was to compare single-arc (SA) and double-arc (DA) treatment plans, which are planning techniques often used in prostate cancer volumetric modulated arc therapy (VMAT), in the presence of intrafractional deformation (ID) to determine which technique is superior in terms of target dose coverag...

journal_title：Journal of radiation research

authors： Varnava M,Sumida I,Oda M,Kurosu K,Isohashi F,Seo Y,Otani K,Ogawa K

更新日期：2020-12-21 00:00:00

abstract：:The purpose of this study is to evaluate the dose-volume metrics under different heterogeneity corrections and the factors associated with local recurrence (LR) after stereotactic body radiation therapy (SBRT) for non-small-cell lung cancer (NSCLC). Eighty-three patients who underwent SBRT for pathologically proven st...

journal_title：Journal of radiation research

authors： Ueki N,Matsuo Y,Shibuya K,Nakamura M,Narabayashi M,Sakanaka K,Norihisa Y,Mizowaki T,Hiraoka M

更新日期：2013-03-01 00:00:00

abstract：:The increasing use of mobile phones has aroused public concern regarding the potential health risks of radiofrequency (RF) fields. We investigated the effects of exposure to RF fields (2.45 GHz, continuous wave) at specific absorption rate (SAR) of 1, 5, and 10 W/kg for 1, 4, and 24 h on gene expression in a normal hu...

journal_title：Journal of radiation research

authors： Sakurai T,Kiyokawa T,Narita E,Suzuki Y,Taki M,Miyakoshi J

更新日期：2011-01-01 00:00:00