Long-term pathological and immunohistochemical features in the liver after intraoperative whole-liver irradiation in rats.

abstract：:We compared the tumor reoxygenation patterns in three different murine tumor cell lines after X-irradiation with those after carbon-beam irradiation using a heavy-ion medical accelerator (HIMAC) system. The tumors of the cell lines SCCVII, SCCVII-variant-1 and EMT6 on the hind legs of mice received local priming irrad...

journal_title：Journal of radiation research

authors： Oya N,Sasai K,Shibata T,Takagi T,Shibuya K,Koike S,Nojima K,Furusawa Y,Ando K,Hiraoka M

更新日期：2001-06-01 00:00:00

abstract：:The purpose of this study is to survey the current patterns of practice, and barriers to implementation, of 3D image-guided brachytherapy (3D-IGBT) for cervical cancer in Japan. A 30-item questionnaire was sent to 171 Japanese facilities where high-dose-rate brachytherapy devices were available in 2012. In total, 135 ...

journal_title：Journal of radiation research

authors： Ohno T,Toita T,Tsujino K,Uchida N,Hatano K,Nishimura T,Ishikura S

更新日期：2015-11-01 00:00:00

abstract：:In Japan, the use of adjuvant radiotherapy after prostatectomy for prostate cancer has not increased compared with the use of salvage radiotherapy. We retrospectively evaluated the outcome of adjuvant radiotherapy together with prognostic factors of outcome in Japan. Between 2005 and 2007, a total of 87 patients were ...

journal_title：Journal of radiation research

authors： Aoki M,Mizowaki T,Akimoto T,Nakamura K,Ejima Y,Jingu K,Tamai Y,Nakajima N,Takemoto S,Kokubo M,Katoh H

更新日期：2014-05-01 00:00:00

abstract：:The purpose of this study was to describe the results of definitive radiotherapy (RT) with concurrent chemotherapy for maxillary sinus carcinomas (MSCs) with neck lymph node metastasis to clarify its limitation. Local control (LC), progression-free survival (PFS) and overall survival (OS) rates were calculated using t...

journal_title：Journal of radiation research

authors： Abe T,Saito S,Iino M,Aoshika T,Ryuno Y,Ohta T,Igari M,Hirai R,Kumazaki Y,Ebihara Y,Nakahira M,Sugasawa M,Noda SE,Kato S

更新日期：2021-01-01 00:00:00

abstract：:The present paper is part of an attempt at finally reconstructing the realities of nuclear tests and their human effects near Semipalatinsk, Kazakhstan. As a first step, it tries to reconstruct the overall image of nuclear tests and their human effects. Our data are 199 written testimonies of those affected by radiati...

journal_title：Journal of radiation research

authors： Matsuo M,Kawano N,Satoh K,Apsalikov KN,Moldagaliev T

更新日期：2006-02-01 00:00:00

abstract：:Male C3H/HeN mice were exposed to 252Cf radiation and mated with unirradiated C57BL/6N females. F1 mice were analyzed for germline mutation at the paternally derived C3H/HeN allele of a hypervariable minisatellite locus, Ms6hm. This locus exhibited a high frequency of length change mutation spontaneously, and the muta...

journal_title：Journal of radiation research

authors： Niwa O,Fan YJ,Numoto M,Kamiya K,Kominami R

更新日期：1996-09-01 00:00:00

abstract：:While recent advances in elucidating the enzyme/substrate relationship of phosphorylation cascades have demonstrated several distinct pathways in membrane-cytoplasm signaling, the molecular dissection of p53 and the products of other proto-oncogenes have greatly promoted the studies of nuclear signaling and expanded t...

journal_title：Journal of radiation research

authors： Wang X,Ohnishi T

更新日期：1997-09-01 00:00:00

abstract：:The purpose of this study is to investigate the normal tissue damage caused by carbon-ion therapy. We measured chromosomal aberrations in peripheral blood lymphocytes before, during, and after radiotherapy, using the techniques of fluorescence in situ hybridization (FISH) and chemically induced premature chromosome co...

journal_title：Journal of radiation research

authors： Lee R,Yamada S,Yamamoto N,Miyamoto T,Ando K,Durante M,Tsujii H

更新日期：2004-06-01 00:00:00

abstract：:Modern treatment machines have shown small inter-unit variability regarding beam data. Recently, vendor-provided average beam data, such as the Representative Beam Data (RBD) of the TrueBeam (Varian Medical Systems, Palo Alto, CA, USA), has been used for modeling of the Eclipse (Varian Medical Systems) treatment plann...

journal_title：Journal of radiation research

authors： Isono M,Akino Y,Mizuno H,Tanaka Y,Masai N,Yamamoto T

更新日期：2020-03-23 00:00:00

abstract：:We evaluated the efficacy and safety of stereotactic body radiation therapy (SBRT) for patients with head and neck tumors. From April 2005 through April 2008, 34 patients with head and neck tumors were treated with CyberKnife SBRT. Twenty-one of them had prior radiotherapy. Treatment sites were orbit (n = 7), cervical...

journal_title：Journal of radiation research

authors： Kodani N,Yamazaki H,Tsubokura T,Shiomi H,Kobayashi K,Nishimura T,Aibe N,Ikeno H,Nishimura T

更新日期：2011-01-01 00:00:00

abstract：:The 239Pu distribution in the 12.5-day-old rat conceptus was compared between in vivo and in vitro experimental systems to establish a possible mechanism of cross-placental transfer of this radionuclide. In the in vivo study, plutonium citrate solution was injected intravenously to pregnant Wistar rats. In the in vitr...

journal_title：Journal of radiation research

authors： Takahashi S,Sato H,Kubota Y,Inaba J

更新日期：1992-12-01 00:00:00

abstract：:The expression of oncogenes was studied in 12 types of 178 mouse tumors induced by radiations and chemicals. DNA was analyzed in tumors in which the overexpression of oncogenes was noted. Amplification of the myc oncogene was found in chemically induced sarcomas, but not in sarcomas induced by radiation. Activation of...

journal_title：Journal of radiation research

authors： Niwa O,Muto M,Suzuki F,Kominami R,Yokoro K

更新日期：1991-12-01 00:00:00

abstract：:External beam radiotherapy is a potential salvage or adjuvant therapy after radical prostatectomy (RP). The purpose of this study was to investigate the treatment outcome of salvage radiotherapy (RT) following RP for clinically localized prostate cancer and to identify factors that may predict the outcome of salvage R...

journal_title：Journal of radiation research

authors： Hayashi S,Hayashi K,Yoshimura R,Masuda H,Kihara K,Shibuya H

更新日期：2012-09-01 00:00:00

abstract：:The effect of gamma-irradiation on a major nutritional function of the yolk sac (the uptake and digestion of macromolecular materials) was studied in rat visceral yolk sacs cultured in vitro being used 125I-labeled bovine serum albumin (RISA) as the tracer protein. The uptake of RISA (per g wet weight) by rat yolk sac...

journal_title：Journal of radiation research

authors： Takahashi S,Koshimoto C,Kubota Y

更新日期：1993-06-01 00:00:00

abstract：:A photoluminescence glass dosimeter, GD-301, was applied to the measurement of low absorbed doses in mice exposed to low-dose rate 137Cs gamma-rays. The dosimeter system consists of small rod-shaped glass chip detectors capable of embedded in the body of a mouse and an automatic readout device equipped with a standard...

journal_title：Journal of radiation research

authors： Hoshi Y,Nomura T,Oda T,Iwasaki T,Fujita K,Ishikawa T,Kato A,Ikegami T,Sakai K,Tanooka H,Yamada T

更新日期：2000-06-01 00:00:00

abstract：:Six Japanese patients in Hokkaido area were diagnosed as xeroderma pigmentosum (XP) at two University Hospital; one patient, a 29 years old female (XP2AS) at Asahikawa Medical College, and five patients, namely, a 53 years old male (XP1SA), a 45 years old female (XP2SA), a 46 years old female (XP3SA), a 47 years old m...

journal_title：Journal of radiation research

authors： Fujikawa K,Ayaki H,Ishizaki K,Takatera H,Matsuo S,Iizuka H,Koizumi H,Ikenaga M

更新日期：1994-09-01 00:00:00

abstract：:The brachytherapy dose calculations used in treatment planning systems (TPSs) have conventionally been performed assuming homogeneous water. Using measurements and a Monte Carlo simulation, we evaluated the dosimetric impact of an air passage on brachytherapy for bronchus cancer. To obtain the geometrical characterist...

journal_title：Journal of radiation research

authors： Okamoto H,Wakita A,Nakamura S,Nishioka S,Aikawa A,Kato T,Abe Y,Kobayashi K,Inaba K,Murakami N,Itami J

更新日期：2016-11-01 00:00:00

abstract：:The Radiation Effects Research Foundation (RERF) continues to conduct a follow-up study initiated some years ago of cancer mortality and incidence among the survivors of the atomic bombing of Hiroshima and Nagasaki exposed in utero. Although only 18 incident cases of cancer were identified in the years 1950-1984 (of w...

journal_title：Journal of radiation research

authors： Yoshimoto Y,Kato H,Schull WJ

更新日期：1991-03-01 00:00:00

abstract：:The prognosis and treatment of thyroid cancer depends on the type and stage of the disease. Radiosensitivity differs among cancer cells owing to their varying capacity for repair after irradiation. Radioactive iodine can be used to destroy thyroid cancer cells. However, patient prognosis and improvement after irradiat...

journal_title：Journal of radiation research

authors： Ihara M,Ashizawa K,Shichijo K,Kudo T

更新日期：2019-03-01 00:00:00

abstract：:The aim of the study was to investigate the various effects of high linear energy transfer (LET) carbon ion (12C6+) and low LET X-ray radiation on MDA-MB-231 and MCF-7 human breast cancer cells and to explore the underlying mechanisms of radiation sensitivity. Cell proliferation, cell colony formation, cell cycle dist...

journal_title：Journal of radiation research

authors： Zhang Q,Kong Y,Yang Z,Liu Y,Liu R,Geng Y,Luo H,Zhang H,Li H,Feng S,Wang X

更新日期：2020-05-22 00:00:00

abstract：:Radiotherapy is an integral part of overall cancer therapy. One of the most serious adverse effects of irradiation concern, for long-term survivors, the development of post-radiation sarcoma (PRS) in healthy tissues located within the irradiated area. PRS have bad prognosis and are often detected at a late stage. Ther...

journal_title：Journal of radiation research

authors： Phulpin B,Tran N,Leroux A,Poussier S,Marie PY,Pinel S,Huger S,Henrot P,Gallet P,Blaise C,Bravetti P,Graff P,Merlin JL,Dolivet G

更新日期：2012-01-01 00:00:00

abstract：:This study was conducted in order to evaluate the cytotoxicity of high linear-energy-transfer (LET) ionizing radiation (IR) on glioblastoma cells and fibroblasts using different modes of cell inactivation assays. Two human glioblastoma cell lines with or without p53-mutation, and fibroblasts were used as materials. Ga...

journal_title：Journal of radiation research

authors： Tsuboi K,Moritake T,Tsuchida Y,Tokuuye K,Matsumura A,Ando K

更新日期：2007-07-01 00:00:00

abstract：:Carbon-ion therapy by layer-stacking irradiation for static targets has been practised in clinical treatments. In order to apply this technique to a moving target, disturbances of carbon-ion dose distributions due to respiratory motion have been studied based on the measurement using a respiratory motion phantom, and ...

journal_title：Journal of radiation research

authors： Tajiri S,Tashiro M,Mizukami T,Tsukishima C,Torikoshi M,Kanai T

更新日期：2017-11-01 00:00:00

abstract：:An interest in the possible cancer causing ability of neutrons began soon after their discovery. Early use of neutrons from radioactive sources and from cyclotrons led to a need to define risk for such exposures. This need was soon followed by a more tangible need to define risk to the general population of high LET r...

journal_title：Journal of radiation research

authors： Hill CK,Williams-Hill D

更新日期：1999-12-01 00:00:00

abstract：:Since December 2009, after breast-conserving surgery for Stage 0-I cancer of the left breast, 21 women with relatively pendulous breasts underwent computed tomography prone and supine simulations. The adjuvant radiotherapy was 50 Gy in 25 fractions to the left breast alone. Four plans--conventional wedged tangents and...

journal_title：Journal of radiation research

authors： Chen JL,Cheng JC,Kuo SH,Chan HM,Huang YS,Chen YH

更新日期：2013-09-01 00:00:00

abstract：:We generated low-flux X-ray micro-planar beams (MPBs) using a laboratory-scale industrial X-ray generator (60 kV/20 mA) with custom-made collimators with three different peak/pitch widths (50/200 μm, 100/400 μm, 50/400 μm). To evaluate normal skin reactions, the thighs of C3H/HeN mice were exposed to 100 and 200 Gy MP...

journal_title：Journal of radiation research

authors： Hong Z,Zenkoh J,Le B,Gerelchuluun A,Suzuki K,Moritake T,Washio M,Urakawa J,Tsuboi K

更新日期：2015-09-01 00:00:00

abstract：:We evaluated toxicity and outcomes for patients with peripheral lung tumors treated with stereotactic body radiation therapy (SBRT) in a dose-escalation and dose-convergence study. A total of 15 patients were enrolled. SBRT was performed with 60 Gy in 5 fractions (fr.) prescribed to the 60% isodose line of maximum dos...

journal_title：Journal of radiation research

authors： Takeda A,Oku Y,Sanuki N,Eriguchi T,Aoki Y,Enomoto T,Kaneko T,Nishimura S,Kunieda E

更新日期：2014-09-01 00:00:00

abstract：:To assess the mutational effects of radiation on vigorously proliferating plant tissue, the mutation spectrum was analyzed with Arabidopsis seedlings using the plasmid-rescue method. Transgenic plants containing the Escherichia coli rpsL gene were irradiated with γ-rays and carbon ion beams (320-MeV (12)C(6+)), and mu...

journal_title：Journal of radiation research

authors： Yoshihara R,Nozawa S,Hase Y,Narumi I,Hidema J,Sakamoto AN

更新日期：2013-11-01 00:00:00

abstract：:In this study, a novel combination treatment of armed oncolytic adenovirus expressing interleukin 12 (IL-12) and granulocyte-macrophage colony-stimulating factor (GM-CSF) with radiation was investigated for antitumor and antimetastatic effect in a murine hepatic cancer (HCa-I) model. Tumor bearing syngeneic mice were ...

journal_title：Journal of radiation research

authors： Kim W,Seong J,Oh HJ,Koom WS,Choi KJ,Yun CO

更新日期：2011-01-01 00:00:00

abstract：:Surgery is the standard modality for early-stage I-II non-small-cell lung cancer (NSCLC). Generally, patients who are >80 years old tend to have more comorbidities and inferior physical status than younger patients. Stereotactic body radiation therapy (SBRT) may provide an alternative treatment for this group of patie...

journal_title：Journal of radiation research

authors： Bei Y,Murakami N,Nakayama Y,Okuma K,Kashihara T,Raturi VP,Okamoto H,Takahashi K,Inaba K,Igaki H,Itami J

更新日期：2020-07-06 00:00:00