Transfer of plutonium to rat embryos in vivo and in vitro.

abstract：:We examined the use of the mouse Pc-3 ESTR (expanded simple tandem repeat) locus and 72 human microsatellite loci as potentially sensitive biomarkers for mutagenic exposures to germ cells in mice and humans respectively. In the mouse work, we treated male mice with TCDD (2, 3, 7, 8-tetrachlorodibenzo-p-dioxin; a chemi...

journal_title：Journal of radiation research

authors： Ryo H,Nakajima H,Nomura T

更新日期：2006-01-01 00:00:00

abstract：:In this review, we would like to introduce a unique approach for the estimation of radioadaptation. Recently, we proposed a new methodology for evaluating the repair efficiency of DNA double-strand breaks (DSB) using a model system. The model system can trace the fate of a single DSB, which is introduced within intron...

journal_title：Journal of radiation research

authors： Yatagai F,Sugasawa K,Enomoto S,Honma M

更新日期：2009-09-01 00:00:00

abstract：:Exposure to ionizing radiation leads to severe damages in radiosensitive organs and induces acute radiation syndrome, including effects on the hematopoietic system and gastrointestinal system. In this study, the radioprotective ability of KMRC011, a novel toll-like receptor 5 (TLR5) agonist, was investigated in C57BL6...

journal_title：Journal of radiation research

authors： Kim JY,Park JH,Seo SM,Park JI,Jeon HY,Lee HK,Yoo RJ,Lee YJ,Woo SK,Lee WJ,Choi CM,Choi YK

更新日期：2019-07-01 00:00:00

abstract：:The study aimed to detect features of human serum proteome that were associated with exposure to ionizing radiation. The analyzed group consisted of 46 patients treated with radical radiotherapy for larynx cancer; patients were irradiated with total doses in a range from 51 to 72 Gy. Three consecutive blood samples we...

journal_title：Journal of radiation research

authors： Widłak P,Pietrowska M,Wojtkiewicz K,Rutkowski T,Wygoda A,Marczak L,Marczyk M,Polańska J,Walaszczyk A,Domińczyk I,Składowski K,Stobiecki M,Polański A

更新日期：2011-01-01 00:00:00

abstract：:In this study, a novel combination treatment of armed oncolytic adenovirus expressing interleukin 12 (IL-12) and granulocyte-macrophage colony-stimulating factor (GM-CSF) with radiation was investigated for antitumor and antimetastatic effect in a murine hepatic cancer (HCa-I) model. Tumor bearing syngeneic mice were ...

journal_title：Journal of radiation research

authors： Kim W,Seong J,Oh HJ,Koom WS,Choi KJ,Yun CO

更新日期：2011-01-01 00:00:00

abstract：:Reassessment of gamma-ray doses from the atomic bombs in Hiroshima and Nagasaki has been carried out with the thermoluminescent measurements of bricks and decorative tiles which were collected from the buildings that remain as they were at the time of the explosions. The thermoluminescent measurements were performed u...

journal_title：Journal of radiation research

authors： Maruyama T,Kumamoto Y,Noda Y

更新日期：1991-03-01 00:00:00

abstract：:Wistar rats inhaled 239PuO2 particles prepared by the calcination of 239Pu hydroxide at 1150 and 400 degrees C. Lung retention, fecal and urinary excretion, and translocation of 239Pu were compared between the two calcination temperatures. The clearance of 239Pu from the lungs was significantly faster in the rats expo...

journal_title：Journal of radiation research

authors： Sato H,Yamada Y,Ishigure N,Nakano T,Enomoto H,Takahashi S,Kubota Y,Inaba J

更新日期：1999-06-01 00:00:00

abstract：:Female C3H strain mice, which do not spontaneously exhibit frequent bone tumors and myeloid leukemias, were injected intraperitoneally with various doses of 10 to 12,000 Bq/animal of monomeric 239Pu citrate to clarify lifetime carcinogenesis caused by alpha-particles distributed mainly in the skeleton. Survival time w...

journal_title：Journal of radiation research

authors： Oghiso Y,Yamada Y,Iida H

更新日期：1997-06-01 00:00:00

abstract：:The aim of this study was to compare the dosimetric parameters of whole-pelvic radiotherapy (WPRT) for cervical cancer among plans involving 3D conformal radiotherapy (3D-CRT), intensity-modulated radiotherapy (IMRT), or spot-scanning proton therapy (SSPT). The dose distributions of 3D-CRT-, IMRT-, and SSPT-based WPRT...

journal_title：Journal of radiation research

authors： Hashimoto S,Shibamoto Y,Iwata H,Ogino H,Shibata H,Toshito T,Sugie C,Mizoe JE

更新日期：2016-09-01 00:00:00

abstract：:The aim of this study was to carry out geometric and dosimetric evaluation of the usefulness of a deformable image registration algorithm utilized for adaptive head-and-neck intensity-modulated radiotherapy. Data consisted of seven patients, each with a planning CT (pCT), a rescanning CT (ReCT) and a cone beam CT (CBC...

journal_title：Journal of radiation research

authors： Eiland RB,Maare C,Sjöström D,Samsøe E,Behrens CF

更新日期：2014-09-01 00:00:00

abstract：:The purpose of this study is to investigate the normal tissue damage caused by carbon-ion therapy. We measured chromosomal aberrations in peripheral blood lymphocytes before, during, and after radiotherapy, using the techniques of fluorescence in situ hybridization (FISH) and chemically induced premature chromosome co...

journal_title：Journal of radiation research

authors： Lee R,Yamada S,Yamamoto N,Miyamoto T,Ando K,Durante M,Tsujii H

更新日期：2004-06-01 00:00:00

abstract：:As a part of technical improvements of chromosome aberration analysis on human peripheral lymphocytes for biological radiation dosimetry, we examined the optimal conditions for the use of colcemid in chromosome preparation in order to obtain enough number of cells at metaphase in the first cell division. When treated ...

journal_title：Journal of radiation research

authors： Kanda R,Jiang T,Hayata I,Kobayashi S

更新日期：1994-03-01 00:00:00

abstract：:Thyroid cells were given 5.5 Gy X-rays in situ and transplanted after 1 day or after 6 weeks to form colonies in fat pads. The colony-forming efficiency unexpectedly decreased by a factor of about 2 with this increase in delay time before transplantation. In addition, there was a concomitant marked increase above the ...

journal_title：Journal of radiation research

authors： Watanabe H,Hendry JH

更新日期：1994-06-01 00:00:00

abstract：:To evaluate the present levels of 239,240Pu and U in residents living near the Semipalatinsk nuclear test site, more than 70 bone samples were obtained at autopsy. The subjects ranged in age from 30 to 86 years (mean 59.3+/-12.9). Most of the samples consisted of victims who died of various diseases. Plutonium and U w...

journal_title：Journal of radiation research

authors： Yamamoto M,Hoshi M,Sakaguchi A,Shinohara K,Kurihara O,Apsalikov KN,Gusev BI

更新日期：2006-02-01 00:00:00

abstract：:Single-photon emission computed tomography/computed tomography (SPECT/CT) demonstrates the precise location of the sentinel lymph nodes (SLNs) in patients with breast cancer. We evaluated the relationship between SLNs and postoperative tangential fields by using SPECT/CT images. Subjects included 72 patients with earl...

journal_title：Journal of radiation research

authors： Wadasaki K,Nishibuchi I

更新日期：2015-09-01 00:00:00

abstract：:The purpose of this study was to analyze the clinical outcomes of simultaneous modulated accelerated radiotherapy (SMART) in patients with nasopharyngeal carcinoma (NPC). A total of 97 patients who underwent SMART for NPC between August 2005 and November 2011 were evaluated. The prescribed dose was 69.9 Gy/30 fraction...

journal_title：Journal of radiation research

authors： Tang JM,Ma XM,Hou YL,Dai LY,Cao HB,Ye M,Bai YR

更新日期：2014-07-01 00:00:00

abstract：:In case of an accidental overexposure to ionizing radiation where the dose received by the victim is over 5 Gy, the conventional biological indicator of dose, the dicentric assay, does not provide an accurate enough dose measurement. A more appropriate technique is to measure ring chromosomes in stimulated lymphocytes...

journal_title：Journal of radiation research

authors： Lamadrid AI,García O,Delbos M,Voisin P,Roy L

更新日期：2007-01-01 00:00:00

abstract：:Liquid ionization chambers (LICs) are highly sensitive to dose irradiation and have small perturbations because of their liquid-filled sensitive volume. They require a sensitive volume much smaller than conventional air-filled chambers. However, it has been reported that the collection efficiency has dependencies on t...

journal_title：Journal of radiation research

authors： Takei H,Isobe T,Kitamura N,Mori Y,Tomita T,Kobayashi D,Kamizawa S,Sato T,Sakurai H,Sakae T

更新日期：2018-05-01 00:00:00

abstract：:The aim of this study was to compare the anti-oxidative and anti-inflammatory activities of gamma-irradiated persimmon leaf extract (GPLE) with those of non-irradiated persimmon leaf extract (PLE). Ethanolic extract of persimmon leaf was exposed to gamma irradiation at a dose of 10 kGy. After gamma irradiation, the co...

journal_title：Journal of radiation research

authors： Cho BO,Nchang Che D,Yin HH,Jang SI

更新日期：2017-09-01 00:00:00

abstract：:Clustered DNA damage is a specific type of DNA damage induced by ionizing radiation. Any type of ionizing radiation traverses the target DNA molecule as a beam, inducing damage along its track. Our previous study showed that clustered DNA damage yields decreased with increased linear energy transfer (LET), leading us ...

journal_title：Journal of radiation research

authors： Tokuyama Y,Furusawa Y,Ide H,Yasui A,Terato H

更新日期：2015-05-01 00:00:00

abstract：:When DNA is damaged by exposure to a small amount of radiation, it is repaired efficiently by innate mechanisms. However, if cellular damage is more extensive, DNA repair cannot be adequately completed. To clarify the role of the p53 gene in apoptotic tissue repair, the incidence of in-vivo radiation-induced somatic m...

journal_title：Journal of radiation research

authors： Kato F,Kakihara H,Kunugita N,Ootsuyama A,Norimura T

更新日期：2002-12-01 00:00:00

abstract：:The paper describes the development of chemical modules simulating the prechemical and chemical stages of charged particle tracks in pure liquid water. These calculations are based on our physical track structure codes for electrons and ions (KURBUC, LEPHIST and LEAHIST) which provide the initial spatial distribution ...

journal_title：Journal of radiation research

authors： Uehara S,Nikjoo H

更新日期：2006-03-01 00:00:00

abstract：:Thermionic emission (TE)-type X-ray generators have been exclusively used in medicine, but there are many difficulties in making these X-ray sources compact. A field emission (FE)-type X-ray generator using carbon nanotubes is a newly-developed compact system that can be as small as several cm in length. Considering t...

journal_title：Journal of radiation research

authors： Nakazato T,Nakanishi M,Kita S,Okuyama F,Shibamoto Y,Otsuka T

更新日期：2007-03-01 00:00:00

abstract：:A photoluminescence glass dosimeter, GD-301, was applied to the measurement of low absorbed doses in mice exposed to low-dose rate 137Cs gamma-rays. The dosimeter system consists of small rod-shaped glass chip detectors capable of embedded in the body of a mouse and an automatic readout device equipped with a standard...

journal_title：Journal of radiation research

authors： Hoshi Y,Nomura T,Oda T,Iwasaki T,Fujita K,Ishikawa T,Kato A,Ikegami T,Sakai K,Tanooka H,Yamada T

更新日期：2000-06-01 00:00:00

abstract：:Radiotherapy-induced toxicity is a major dose-limiting factor in anti-cancer treatment. Ionizing radiation leads to the formation of reactive oxygen and nitrogen species (ROS/RNS) that are associated with radiation-induced cell death. Investigations of biological effects of fullerenol have provided evidence for its RO...

journal_title：Journal of radiation research

authors： Bogdanović V,Stankov K,Icević I,Zikic D,Nikolić A,Solajić S,Djordjević A,Bogdanović G

更新日期：2008-05-01 00:00:00

abstract：:X-ray induced neoplastic transformation of C3H/10T1/2 cells was suppressed equally by Lipid A and LPS. We examined the effects of several modifiers of arachidonic acid (AA) metabolism in our investigation on the suppression mechanism of LPS. Dexamethasone (DM), an inhibitor of phospholipase A2 (PLA2), abolished the ef...

journal_title：Journal of radiation research

authors： Sakiyama H,Yasukawa M,Nishijima M,Wada E,Kanegasaki S

更新日期：1993-12-01 00:00:00

abstract：:Since December 2009, after breast-conserving surgery for Stage 0-I cancer of the left breast, 21 women with relatively pendulous breasts underwent computed tomography prone and supine simulations. The adjuvant radiotherapy was 50 Gy in 25 fractions to the left breast alone. Four plans--conventional wedged tangents and...

journal_title：Journal of radiation research

authors： Chen JL,Cheng JC,Kuo SH,Chan HM,Huang YS,Chen YH

更新日期：2013-09-01 00:00:00

abstract：:Reactions of edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one) with deoxyguanosine monophosphate (dGMP) hydroxyl radical adducts were investigated by pulse radiolysis technique. Edaravone was found to reduce the dGMP hydroxyl radical adducts through electron transfer reactions. The rate constants of the reactions were g...

journal_title：Journal of radiation research

authors： Hata K,Urushibara A,Yamashita S,Lin M,Muroya Y,Shikazono N,Yokoya A,Fu H,Katsumura Y

更新日期：2015-01-01 00:00:00

abstract：:New precision radiotherapy (RT) techniques reduce the uncertainties in localizing soft and moving tumors. However, there are still many uncontrollable internal organ movements. In our study, patients who underwent neoadjuvant chemoradiotherapy (NA-CRT) for rectal cancer were evaluated to determine inter-fraction mesor...

journal_title：Journal of radiation research

authors： Alickikus ZA,Kuru A,Aydin B,Akcay D,Gorken IB

更新日期：2020-03-23 00:00:00

abstract：:X-ray induced formation of micronuclei is generally thought to result from DNA double-strand breaks (DSBs). However, DNA DSBs inhibit the cell cycle progression that is required for micronucleus formation. In order to reconcile this apparent discrepancy, we investigated whether DNA DSBs induced during the G1 phase cou...

journal_title：Journal of radiation research

authors： Okada T,Kashino G,Nishiura H,Tano K,Watanabe M

更新日期：2012-01-01 00:00:00