Radiation-related changes in serum proteome profiles detected by mass spectrometry in blood of patients treated with radiotherapy due to larynx cancer.

abstract：:The aim of this study was to determine the outcomes and adverse events for 300 men with prostate cancer treated with 125iodine (125I) brachytherapy with and without external-beam radiation therapy (EBRT) at a single institution in Japan. Between February 2005 and November 2011, 300 consecutive patients with clinically...

journal_title：Journal of radiation research

authors： Maki S,Itoh Y,Kubota S,Okada T,Nakahara R,Ito J,Kawamura M,Naganawa S,Yoshino Y,Fujita T,Kato M,Gotoh M,Ikeda M

更新日期：2017-11-01 00:00:00

abstract：:Modern treatment machines have shown small inter-unit variability regarding beam data. Recently, vendor-provided average beam data, such as the Representative Beam Data (RBD) of the TrueBeam (Varian Medical Systems, Palo Alto, CA, USA), has been used for modeling of the Eclipse (Varian Medical Systems) treatment plann...

journal_title：Journal of radiation research

authors： Isono M,Akino Y,Mizuno H,Tanaka Y,Masai N,Yamamoto T

更新日期：2020-03-23 00:00:00

abstract：:We propose a clinical workflow of stereotactic volumetric modulated arc therapy (VMAT) for a lung tumor from planning to tumor position verification using 4D planning computed tomography (CT) and 4D cone-beam CT (CBCT). A 4D CT scanner, an Anzai belt and a BodyFix were employed to obtain 10-phase respiratory-correlate...

journal_title：Journal of radiation research

authors： Nakagawa K,Haga A,Kida S,Masutani Y,Yamashita H,Takahashi W,Sakumi A,Saotome N,Shiraki T,Ohtomo K,Iwai Y,Yoda K

更新日期：2013-01-01 00:00:00

abstract：:The aim of the study was to evaluate inter-fractional dosimetric variations for high-dose rate breast brachytherapy using a strut-adjusted volume implant (SAVI). For the nine patients included, dosimetric constraints for treatment were as follows: for the planning target volume for evaluation (PTV_Eval), the volume re...

journal_title：Journal of radiation research

authors： Iijima K,Okamoto H,Takahashi K,Aikawa A,Wakita A,Nakamura S,Nishioka S,Harada K,Notake R,Sugawara A,Yoshimura R,Kunieda E,Itami J

更新日期：2020-01-23 00:00:00

abstract：:Immediately after X-irradiation, monocytic cells can express the gene for interleukin (IL)-1beta, which enhances inflammation and contributes to radioprotection in mice. In order to analyze the mechanism(s) for the immediate-early induction of IL-1beta after X-irradiation at 20 Gy in cultured murine macrophages, we ex...

journal_title：Journal of radiation research

authors： Ishihara H,Tanaka I,Wan H,Cheeramakara C

更新日期：2003-06-01 00:00:00

abstract：:To evaluate the effect of the sympathetic nervous system on radiation-induced apoptosis in jejunal crypt cells, apoptosis levels were compared in spontaneously hypertensive rats (SHR), animals which are a genetic hyperfunction model of the sympathetic nervous system, and normotensive Wistar-Kyoto rats (WKY). SHR and W...

journal_title：Journal of radiation research

authors： Matsuu M,Shichijo K,Nakamura Y,Ikeda Y,Naito S,Ito M,Okaichi K,Sekine I

更新日期：2000-03-01 00:00:00

abstract：:Immunohistochemical examinations were performed on rat pulmonary tumors induced by inhalation exposures to 239PuO2 aerosols, or by X-ray-irradiation to identify and compare cellular origins or, in turn, target cells at risk for radiation carcinogenesis. Both plutonium-induced and X-ray-induced pulmonary tumors appeare...

journal_title：Journal of radiation research

authors： Oghiso Y,Yamada Y

更新日期：2002-09-01 00:00:00

abstract：:The Rho-associated coiled-coil-containing protein kinase (ROCK) pathway is known to influence metastasis in several cancers; however, the impact of the pathway on clinical outcomes in patients undergoing radiotherapy remains unknown. In the present study, the expression of RhoA, RhoC, ROCK-1, ROCK-2 and p53 was immuno...

journal_title：Journal of radiation research

authors： Tanaka K,Matsumoto Y,Ishikawa H,Fukumitsu N,Numajiri H,Murofushi K,Oshiro Y,Okumura T,Satoh T,Sakurai H

更新日期：2020-03-23 00:00:00

abstract：:The purpose of this study was to evaluate interfractional changes of the minimum dose delivered to 90% of the high-risk clinical target volume (HR-CTV D90) and D2cc of the bladder and rectum during brachytherapy for uterine cervical cancer patients. A total of 52 patients received external beam radiotherapy and high-d...

journal_title：Journal of radiation research

authors： Ohkubo Y,Ohno T,Noda SE,Kubo N,Nakagawa A,Kawahara M,Abe T,Kiyohara H,Wakatsuki M,Nakano T

更新日期：2013-11-01 00:00:00

abstract：:We examined dose-dependent or dose rate-dependent changes of superoxide dismutase (SOD) activity using a new large-scale facility for exposing small animals to radon. Mice were exposed to radon at a concentration of 250, 500, 1000, 2000, or 4000 Bq/m(3) for 0.5, 1, 2, 4, or 8 days. When mice were exposed to radon at 2...

journal_title：Journal of radiation research

authors： Kataoka T,Sakoda A,Ishimori Y,Toyota T,Nishiyama Y,Tanaka H,Mitsunobu F,Yamaoka K

更新日期：2011-01-01 00:00:00

abstract：:Halobacterium salinarium, a member of the extremely halophilic archaebacteria, contains a C50-carotenoid namely bacterioruberin. We have previously reported the high resistance of this organism against the lethal actions of DNA-damaging agents including ionizing radiation and ultraviolet light (UV). In this study, we ...

journal_title：Journal of radiation research

authors： Shahmohammadi HR,Asgarani E,Terato H,Saito T,Ohyama Y,Gekko K,Yamamoto O,Ide H

更新日期：1998-12-01 00:00:00

abstract：:Pericardial effusion is an important late toxicity after concurrent chemoradiotherapy (CCRT) for locally advanced esophageal cancer. We investigated the clinical and dosimetric factors that were related to pericardial effusion among patients with thoracic esophageal cancer who were treated with definitive CCRT using t...

journal_title：Journal of radiation research

authors： Takata N,Kataoka M,Hamamoto Y,Tsuruoka S,Kanzaki H,Uwatsu K,Nagasaki K,Mochizuki T

更新日期：2018-05-01 00:00:00

abstract：:This study aimed to clarify the motivations and timing of the decision to become radiation oncologists. MATERIALS AND METHODS:We conducted an online survey for new members of the Japanese Society for Radiation Oncology (JASTRO). RESULTS:The response rate was 43.3%. Data of the 79 respondents who wanted to obtain a b...

journal_title：Journal of radiation research

authors： Murakami Y,Noda SE,Hatayama Y,Maebayashi T,Jingu K,Nagata Y,Mizowaki T

更新日期：2020-09-08 00:00:00

abstract：:Low doses (2.5-15 cGy) of X-irradiation two months prior to a second exposure to a sublethal dose enhanced the survival rate in mice. Optimal and significant increase was observed with 5-10 cGy. Endogenous spleen colony counts (endo-CFUs) after 7 Gy increased by a factor of about 1.7 in mice pre-irradiated with 5-10 c...

journal_title：Journal of radiation research

authors： Yonezawa M,Takeda A,Misonoh J

更新日期：1990-09-01 00:00:00

abstract：:In hypofractionated stereotactic radiotherapy (SRT), high doses per fraction are usually used and the dose delivery pattern is different from that of conventional radiation. The daily dose is usually given intermittently over a longer time compared with conventional radiotherapy. During prolonged radiation delivery, s...

journal_title：Journal of radiation research

authors： Shibamoto Y,Miyakawa A,Otsuka S,Iwata H

更新日期：2016-08-01 00:00:00

abstract：:The increasing use of mobile phones has aroused public concern regarding the potential health risks of radiofrequency (RF) fields. We investigated the effects of exposure to RF fields (2.45 GHz, continuous wave) at specific absorption rate (SAR) of 1, 5, and 10 W/kg for 1, 4, and 24 h on gene expression in a normal hu...

journal_title：Journal of radiation research

authors： Sakurai T,Kiyokawa T,Narita E,Suzuki Y,Taki M,Miyakoshi J

更新日期：2011-01-01 00:00:00

abstract：:Various kinases, such as tyrosine, protein kinase C (PKC) and MAP kinase, play important role in the cellular response to radiation, but little is known about the specific response in the whole animal. Most studies, except a few, are based on single cells. There is a paucity of data where signaling following whole bod...

journal_title：Journal of radiation research

authors： Varadkar PA,Krishna M

更新日期：2004-03-01 00:00:00

abstract：:The purpose of this study was to analyze the patterns of care and outcomes of patients with FIGO Stage I/II cervical cancer who underwent definitive radiotherapy (RT) at multiple Japanese institutions. The Japanese Radiation Oncology Study Group (JROSG) performed a questionnaire-based survey of their cervical cancer p...

journal_title：Journal of radiation research

authors： Ariga T,Toita T,Kato S,Kazumoto T,Kubozono M,Tokumaru S,Eto H,Nishimura T,Niibe Y,Nakata K,Kaneyasu Y,Nonoshita T,Uno T,Ohno T,Iwata H,Harima Y,Wada H,Yoshida K,Gomi H,Numasaki H,Teshima T,Yamada S,Nakano T

更新日期：2015-09-01 00:00:00

abstract：:To evaluate the lifetime hazards of ionizing radiation exposure, 1680 beagles received whole-body, 60-Cobalt gamma exposures or sham-exposures during development. Eight groups of 120 dogs each received mean doses of 16 or 83 cGy at 8 (preimplantation), 28 (embryonic), or 55 (late fetal) days postcoitus (dpc), or 2 (ne...

journal_title：Journal of radiation research

authors： Benjamin SA,Saunders WJ,Angleton GM,Lee AC

更新日期：1991-12-01 00:00:00

abstract：:In this report we update our long-term follow-up results of the prospective study whose aim was to evaluate the efficacy of high-dose-rate (HDR) brachytherapy in combination with external-beam radiotherapy (EBRT) in the treatment of medically inoperable endometrial cancer. Between 1995 and 1998, 29 patients with stage...

journal_title：Journal of radiation research

authors： Inciura A,Atkocius V,Juozaityte E,Vaitkiene D

更新日期：2010-01-01 00:00:00

abstract：:Reactions of edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one) with deoxyguanosine monophosphate (dGMP) hydroxyl radical adducts were investigated by pulse radiolysis technique. Edaravone was found to reduce the dGMP hydroxyl radical adducts through electron transfer reactions. The rate constants of the reactions were g...

journal_title：Journal of radiation research

authors： Hata K,Urushibara A,Yamashita S,Lin M,Muroya Y,Shikazono N,Yokoya A,Fu H,Katsumura Y

更新日期：2015-01-01 00:00:00

abstract：:We evaluated the radiological response and clinical outcome in patients with femoral bone metastases after radiotherapy. 102 consecutive patients with femoral metastases without pathological fracture were treated by surgery or radiotherapy between 2002 and 2005. Twelve of them initially treated with surgery were exclu...

journal_title：Journal of radiation research

authors： Harada H,Katagiri H,Kamata M,Yoshioka Y,Asakura H,Hashimoto T,Furutani K,Takahashi M,Sakahara H,Nishimura T

更新日期：2010-01-01 00:00:00

abstract：:The radioprotective effect of hawthorn (Crataegus microphylla) fruit extract against genotoxicity induced by gamma irradiation has been investigated in mouse bone marrow cells. A single intraperitoneal (ip) administration of hawthorn extract at doses of 25, 50, 100 and 200 mg/kg 1h prior to gamma irradiation (2 Gy) re...

journal_title：Journal of radiation research

authors： Hosseinimehr SJ,Azadbakht M,Mousavi SM,Mahmoudzadeh A,Akhlaghpoor S

更新日期：2007-01-01 00:00:00

abstract：:The purpose of the present study was to develop a hybrid magnetic resonance/computed tomography (MR/CT)-compatible phantom and tissue-equivalent materials for each MR and CT image. Therefore, the essential requirements necessary for the development of a hybrid MR/CT-compatible phantom were determined and the developme...

journal_title：Journal of radiation research

authors： Kim MJ,Lee SR,Song KH,Baek HM,Choe BY,Suh TS

更新日期：2020-03-23 00:00:00

abstract：:X-ray induced formation of micronuclei is generally thought to result from DNA double-strand breaks (DSBs). However, DNA DSBs inhibit the cell cycle progression that is required for micronucleus formation. In order to reconcile this apparent discrepancy, we investigated whether DNA DSBs induced during the G1 phase cou...

journal_title：Journal of radiation research

authors： Okada T,Kashino G,Nishiura H,Tano K,Watanabe M

更新日期：2012-01-01 00:00:00

abstract：:Resveratrol has received considerable attention as a polyphenol with anti-oxidant, anti-carcinogenic, and anti-inflammatory effects. Radiation is an important component of therapy for a wide range of malignant conditions. However, it causes damage to normal cells and, hence, can result in adverse side effects. This st...

journal_title：Journal of radiation research

authors： Jeong MH,Yang KM,Jeong DH,Lee CG,Oh SJ,Jeong SK,Lee KW,Jo YR,Jo WS

更新日期：2014-05-01 00:00:00

abstract：:Neutron dose is transferred to biological materials through the recoil protons produced by elastic scattering. When a low-velocity proton collides with the atoms or molecules of a target, it changes to a hydrogen atom by electron capture; this hydrogen atom then changes to a proton by losing the electron. Because the ...

journal_title：Journal of radiation research

authors： Endo S

更新日期：2004-09-01 00:00:00

abstract：:Direct irradiation may cause malfunctioning of cardiac implantable electronic devices (CIEDs). Therefore, a treatment plan that does not involve direct irradiation of CIEDs should be formulated. However, CIEDs may be directly exposed to radiation because of the sudden intrafractional movement of the patient. The proba...

journal_title：Journal of radiation research

authors： Nakamura K,Aoyama T,Kaneda N,Otsuji M,Minami Y,Sakuragi A,Nakamura M

更新日期：2020-05-22 00:00:00

abstract：:Non-homologous end-joining (NHEJ) is the predominant pathway for the repair of DNA double-strand breaks (DSBs) in human cells. XRCC4 is indispensable to NHEJ and functions together with DNA ligase IV in the rejoining of broken DNA ends. Artemis is a nuclease required for trimming of some, but not all, types of broken ...

journal_title：Journal of radiation research

authors： Katsube T,Mori M,Tsuji H,Shiomi T,Shiomi N,Onoda M

更新日期：2011-01-01 00:00:00

abstract：:To improve treatment conformity for prostate cancer, we investigated daily applicator displacement during high-dose-rate interstitial brachytherapy (HDR-ISBT). Thirty patients treated with HDR-ISBT as monotherapy were examined. All patients received a treatment dosage of 49 Gy per 7 fractions over 4 days. For dose adm...

journal_title：Journal of radiation research

authors： Takenaka T,Yoshida K,Ueda M,Yamazaki H,Miyake S,Tanaka E,Yoshida M,Yoshimura Y,Oka T,Honda K

更新日期：2012-01-01 00:00:00