Abstract:
:Gated radiation therapy is a promising method for improving the dose conformality of treatments to moving targets and reducing the total volume of irradiated tissue. Target motion is of particular concern in proton beam radiotherapy, due to the finite range of proton dose deposition in tissue. Gating allows one to reduce the extent of variation, due to respiration, of the radiological depth to target during treatment delivery. However, respiratory surrogates typically used for gating do not always accurately reflect the position of the internal target. For instance, a phase delay often exists between the internal motion and the motion of the surrogate. Another phenomenon, baseline drifting refers to a gradual change in the exhale position over time, which generally affects the external and internal markers differently. This study examines the influence of these two physiological phenomena on gated radiotherapy using an external surrogate.
journal_name
J Radiat Resjournal_title
Journal of radiation researchauthors
Sharp GC,Lu HM,Trofimov A,Tang X,Jiang SB,Turcotte J,Gierga DP,Chen GT,Hong TSdoi
10.1269/jrr.48.a55subject
Has Abstractpub_date
2007-01-01 00:00:00pages
A55-9eissn
0449-3060issn
1349-9157pii
JST.JSTAGE/jrr/48.A55journal_volume
48 Suppl Apub_type
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