Ectopic expression of miR-34a enhances radiosensitivity of non-small cell lung cancer cells, partly by suppressing the LyGDI signaling pathway.

abstract：:Male C3H/HeN mice were exposed to 252Cf radiation and mated with unirradiated C57BL/6N females. F1 mice were analyzed for germline mutation at the paternally derived C3H/HeN allele of a hypervariable minisatellite locus, Ms6hm. This locus exhibited a high frequency of length change mutation spontaneously, and the muta...

journal_title：Journal of radiation research

authors： Niwa O,Fan YJ,Numoto M,Kamiya K,Kominami R

更新日期：1996-09-01 00:00:00

abstract：:The current study retrospectively analyzed the results of radiotherapy for clinically localized sebaceous carcinoma of the eyelid.We reviewed records of 83 patients with histologically confirmed sebaceous carcinoma who were treated radiotherapeutically between 1983 and 2015. Sixty-five patients (78%) were initially tr...

journal_title：Journal of radiation research

authors： Takagawa Y,Tamaki W,Suzuki S,Inaba K,Murakami N,Takahashi K,Igaki H,Nakayama Y,Shigematsu N,Itami J

更新日期：2019-10-23 00:00:00

abstract：:We have examined the neutron energy dependency of cell killing and mutation induction at the hprt locus in Chinese hamster V79 cells. Monoenergetic neutrons at 0.32, 0.57, and 1.2 MeV were generated at the Hiroshima University Radiobiological Research Accelerator (HIRRAC) Facility, and were used to irradiate cells. Th...

journal_title：Journal of radiation research

authors： Kubota N,Okada S,Nagatomo S,Ozawa F,Inada T,Hill CK,Endo S,Komatsu K

更新日期：1999-12-01 00:00:00

abstract：:We examined dose-dependent or dose rate-dependent changes of superoxide dismutase (SOD) activity using a new large-scale facility for exposing small animals to radon. Mice were exposed to radon at a concentration of 250, 500, 1000, 2000, or 4000 Bq/m(3) for 0.5, 1, 2, 4, or 8 days. When mice were exposed to radon at 2...

journal_title：Journal of radiation research

authors： Kataoka T,Sakoda A,Ishimori Y,Toyota T,Nishiyama Y,Tanaka H,Mitsunobu F,Yamaoka K

更新日期：2011-01-01 00:00:00

abstract：:In our previous studies, we found that low-dose radiation inhibits oxidative stress-induced diseases due to increased antioxidants. Although these effects of low-dose radiation were demonstrated, further research was needed to clarify the effects. However, the analysis of oxidative stress is challenging, especially th...

journal_title：Journal of radiation research

authors： Kanzaki N,Kataoka T,Etani R,Sasaoka K,Kanagawa A,Yamaoka K

更新日期：2017-01-01 00:00:00

abstract：:We have proposed four dimensional (4D) digitally reconstructed radiography (DRR) for verifying a lung tumor position during volumetric modulated arc therapy (VMAT). An internal target volume (ITV) was defined based on two clinical target volumes (CTVs) delineated on maximum exhalation and maximum inhalation images acq...

journal_title：Journal of radiation research

authors： Nakagawa K,Kida S,Haga A,Masutani Y,Yamashita H,Onoe T,Imae T,Tanaka K,Ohtomo K,Yoda K

更新日期：2012-07-01 00:00:00

abstract：:Several models for the action of mixed irradiation with two types of radiation have been proposed in the last two decades, although the superiority or inferiority of these models is not completely elucidated. However, mixed irradiation is sometimes composed of more than two types of radiation, and for this type of mix...

journal_title：Journal of radiation research

authors： Suzuki S

更新日期：1998-09-01 00:00:00

abstract：:The aim of this study was to carry out geometric and dosimetric evaluation of the usefulness of a deformable image registration algorithm utilized for adaptive head-and-neck intensity-modulated radiotherapy. Data consisted of seven patients, each with a planning CT (pCT), a rescanning CT (ReCT) and a cone beam CT (CBC...

journal_title：Journal of radiation research

authors： Eiland RB,Maare C,Sjöström D,Samsøe E,Behrens CF

更新日期：2014-09-01 00:00:00

abstract：:The International Space Environment Service (ISES) is an international organization for space weather forecasts and belongs to the International Union of Radio Science (URSI). There are eleven ISES forecast centers in the world, and Communications Research Laboratory (CRL) runs the Japanese one. We make forecasts on t...

journal_title：Journal of radiation research

authors： Watari S,Tomita F

更新日期：2002-12-01 00:00:00

abstract：:Boron neutron capture therapy (BNCT) is an emerging radiation treatment modality, exhibiting the potential to selectively destroy cancer cells. Currently, BNCT is conducted using a nuclear reactor. However, the future trend is to move toward an accelerator-based system for use in hospital environments. A typical BNCT ...

journal_title：Journal of radiation research

authors： Hu N,Tanaka H,Takata T,Okazaki K,Uchida R,Sakurai Y

更新日期：2020-03-23 00:00:00

abstract：:The fertility span between the first and the last estrus was compared among female Chinese hamsters exposed to 1 Gy X-rays on neonatal day 0, 2, 4, 6, 8, 10 and 14. The fertility span changed dramatically according to the age at the time of irradiation. The females irradiated on day 4, 6 and 8 showed a definite delay ...

journal_title：Journal of radiation research

authors： Tateno H,Mikamo K

更新日期：1989-06-01 00:00:00

abstract：:The purpose of this study is to survey the current patterns of practice, and barriers to implementation, of 3D image-guided brachytherapy (3D-IGBT) for cervical cancer in Japan. A 30-item questionnaire was sent to 171 Japanese facilities where high-dose-rate brachytherapy devices were available in 2012. In total, 135 ...

journal_title：Journal of radiation research

authors： Ohno T,Toita T,Tsujino K,Uchida N,Hatano K,Nishimura T,Ishikura S

更新日期：2015-11-01 00:00:00

abstract：:In Japan, the use of adjuvant radiotherapy after prostatectomy for prostate cancer has not increased compared with the use of salvage radiotherapy. We retrospectively evaluated the outcome of adjuvant radiotherapy together with prognostic factors of outcome in Japan. Between 2005 and 2007, a total of 87 patients were ...

journal_title：Journal of radiation research

authors： Aoki M,Mizowaki T,Akimoto T,Nakamura K,Ejima Y,Jingu K,Tamai Y,Nakajima N,Takemoto S,Kokubo M,Katoh H

更新日期：2014-05-01 00:00:00

abstract：:Halobacterium salinarium, a member of the extremely halophilic archaebacteria, contains a C50-carotenoid namely bacterioruberin. We have previously reported the high resistance of this organism against the lethal actions of DNA-damaging agents including ionizing radiation and ultraviolet light (UV). In this study, we ...

journal_title：Journal of radiation research

authors： Shahmohammadi HR,Asgarani E,Terato H,Saito T,Ohyama Y,Gekko K,Yamamoto O,Ide H

更新日期：1998-12-01 00:00:00

abstract：:The pulse radiolysis technique has been employed to determine the initiation and propagation rates of different transient species involved in the polymerization of N-isopropylacrylamide (NIPA) in aqueous solutions. Polymerization by anionic mechanism has been observed to be faster than by the free-radical mechanism. T...

journal_title：Journal of radiation research

authors： Acharya A,Mohan H,Sabharwal S

更新日期：2003-12-01 00:00:00

abstract：PURPOSE:To elucidate the mechanism underlying the in vivo radioprotection activity by Zn-containing, heat-treated Saccharomyces cerevisiae yeast (Zn-yeast). MATERIALS AND METHODS:Zn-yeast suspension was administered into C3H/He mice immediately after whole body irradiation (WBI) at 7.5 Gy. Bone marrow was extracted fr...

journal_title：Journal of radiation research

authors： Ueno M,Imadome K,Iwakawa M,Anzai K,Ikota N,Imai T

更新日期：2010-01-01 00:00:00

abstract：:PU-H71, a heat shock protein 90 (Hsp90) inhibitor, has yielded therapeutic efficacy in many preclinical models and is currently in clinical trials. Carbon-ion radiotherapy (CIRT) has provided successful tumor control; however, there is still room for improvement, particularly in terms of tumor-specific radiosensitizat...

journal_title：Journal of radiation research

authors： Li HK,Matsumoto Y,Furusawa Y,Kamada T

更新日期：2016-09-01 00:00:00

abstract：:Photon irradiation has been repeatedly suspected of increasing tumor cell motility and promoting locoregional recurrence of disease. This study was set up to analyse possible mechanisms underlying the potentially radiation-altered motility in medulloblastoma cells. Medulloblastoma cell lines D425 and Med8A were analyz...

journal_title：Journal of radiation research

authors： Rieken S,Rieber J,Brons S,Habermehl D,Rief H,Orschiedt L,Lindel K,Weber KJ,Debus J,Combs SE

更新日期：2015-05-01 00:00:00

abstract：:Six Japanese patients in Hokkaido area were diagnosed as xeroderma pigmentosum (XP) at two University Hospital; one patient, a 29 years old female (XP2AS) at Asahikawa Medical College, and five patients, namely, a 53 years old male (XP1SA), a 45 years old female (XP2SA), a 46 years old female (XP3SA), a 47 years old m...

journal_title：Journal of radiation research

authors： Fujikawa K,Ayaki H,Ishizaki K,Takatera H,Matsuo S,Iizuka H,Koizumi H,Ikenaga M

更新日期：1994-09-01 00:00:00

abstract：:Boron Neutron Capture Therapy (BNCT) effectiveness depends on the preferential sequestration of boron in cancer cells relative to normal tissue cells. We present a novel strategy for sequestering boron using an adenovirus expressing the sodium iodide symporter (NIS). Human glioma grown subcutaneously in athymic mice a...

journal_title：Journal of radiation research

authors： Kumar S,Freytag SO,Barton KN,Burmeister J,Joiner MC,Sedghi B,Movsas B,Binns PJ,Kim JH,Brown SL

更新日期：2010-01-01 00:00:00

abstract：:To evaluate the feasibility of using radiosensitivity of peripheral leukocytes as a predictor of clinical therapeutic responses to radiosurgery in individuals with cerebral arteriovenous malformation (AVM), we enrolled 18 patients years after they had received Gamma Knife radiosurgery for their cerebral AVM. The AVMs ...

journal_title：Journal of radiation research

authors： Guo WY,Pan HC,Wu HM,Hsieh WA,Tsai MH,Chow YM,Chung WY,Shiau CY,Chen SK,Chang WP

更新日期：2004-06-01 00:00:00

abstract：:Inoue and Iwakura recently reported that the specific activity ratio of organically-bound 3H to free water 3H in polished rice samples collected in Japan and China was lower than unity. Their paper was the first to report the systematic apparent elimination of 3H for incorporation to organically-bound form in samples ...

journal_title：Journal of radiation research

authors： Hisamatsu S,Katsumata T,Takizawa Y

更新日期：1991-12-01 00:00:00

abstract：:This study aimed to clarify the motivations and timing of the decision to become radiation oncologists. MATERIALS AND METHODS:We conducted an online survey for new members of the Japanese Society for Radiation Oncology (JASTRO). RESULTS:The response rate was 43.3%. Data of the 79 respondents who wanted to obtain a b...

journal_title：Journal of radiation research

authors： Murakami Y,Noda SE,Hatayama Y,Maebayashi T,Jingu K,Nagata Y,Mizowaki T

更新日期：2020-09-08 00:00:00

abstract：:Thyroid cells were given 5.5 Gy X-rays in situ and transplanted after 1 day or after 6 weeks to form colonies in fat pads. The colony-forming efficiency unexpectedly decreased by a factor of about 2 with this increase in delay time before transplantation. In addition, there was a concomitant marked increase above the ...

journal_title：Journal of radiation research

authors： Watanabe H,Hendry JH

更新日期：1994-06-01 00:00:00

abstract：:Investigating the biological effects of high-LET heavy-ion irradiation at low fluence is important to evaluate the risk of radiation in space. It is especially necessary to detect radiation damage induced by a precise number of heavy ions in individual cells. We thus compared the number of ions traversing a cell and t...

journal_title：Journal of radiation research

authors： Wada S,Kobayashi Y,Funayama T,Natsuhori M,Ito N,Yamamoto K

更新日期：2002-12-01 00:00:00

abstract：:Efficacy of different schedules of HDR brachytherapy in concurrent chemoradiotherapy was evaluated. The study compared the effectiveness of the two HDR brachytherapy schedules which have the same Biological Effective Dose (BED) in locally advanced cervical carcinoma that was treated with concurrent chemoradiotherapy. ...

journal_title：Journal of radiation research

authors： Tharavichitkul E,Klunkin P,Lorvidhaya V,Sukthomya V,Chakrabhandu S,Pukanhaphan N,Chitapanarux I,Galalae R

更新日期：2012-01-01 00:00:00

abstract：:Ionizing radiation induces biological effects not only in irradiated cells but also in non-irradiated cells, which is called the bystander effect. Recently, in vivo and in vitro experiments have suggested that both gap junction hemichannel connexin43 (Cx43) and extracellular adenosine triphosphate (ATP) released from ...

journal_title：Journal of radiation research

authors： Ohshima Y,Tsukimoto M,Harada H,Kojima S

更新日期：2012-07-01 00:00:00

abstract：:Medical diagnostic X-ray workers are one occupational group that has exposure to continuous low doses of external radiation over their working lifetimes. Current ICRP recommendations [ICRP. Recommendations of the International Commission on Radiological Protection. ICRP Publication 60. Ann ICRP 1991;21 (1-3)] state th...

journal_title：Journal of radiation research

authors： Xu XS,Zhang LA,Sun QF,Qin YC,Yu NL

更新日期：2018-03-01 00:00:00

abstract：:In this study, a mechanism in which low-dose hyper-radiosensitivity (HRS) is permanently removed, induced by low-dose-rate (LDR) (0.2-0.3 Gy/h for 1 h) but not by high-dose-rate priming (0.3 Gy at 40 Gy/h) was investigated. One HRS-negative cell line (NHIK 3025) and two HRS-positive cell lines (T-47D, T98G) were used....

journal_title：Journal of radiation research

authors： Edin NJ,Sandvik JA,Vollan HS,Reger K,Görlach A,Pettersen EO

更新日期：2013-11-01 00:00:00

abstract：:We evaluated toxicity and outcomes for patients with peripheral lung tumors treated with stereotactic body radiation therapy (SBRT) in a dose-escalation and dose-convergence study. A total of 15 patients were enrolled. SBRT was performed with 60 Gy in 5 fractions (fr.) prescribed to the 60% isodose line of maximum dos...

journal_title：Journal of radiation research

authors： Takeda A,Oku Y,Sanuki N,Eriguchi T,Aoki Y,Enomoto T,Kaneko T,Nishimura S,Kunieda E

更新日期：2014-09-01 00:00:00