当前位置： SCI文献检索 > JOURNAL OF RADIATION RESEARCH期刊下所有文献 > Radiotherapy for localized sebaceous carcinoma of the eyelid: a retrospective analysis of 83 patients.

Radiotherapy for localized sebaceous carcinoma of the eyelid: a retrospective analysis of 83 patients.

Abstract：

:The current study retrospectively analyzed the results of radiotherapy for clinically localized sebaceous carcinoma of the eyelid.We reviewed records of 83 patients with histologically confirmed sebaceous carcinoma who were treated radiotherapeutically between 1983 and 2015. Sixty-five patients (78%) were initially treated with radiotherapy of curative intent, while the remaining 18 patients underwent postoperative radiotherapy due to tumor recurrence or positive surgical margins. Thirty-seven patients belonged to T1-2, while 46 belonged to T3-4. All 83 patients were treated with radiotherapy with a median radiation dose of 60 Gy. The median follow-up period was 92.1 months (range, 2.8-310.3 months). At the time of analysis, 13 patients (15.1%) died, and 36 patients (43.3%) had local recurrence. The 7-year overall survival, freedom from neck lymph node recurrence, and local control (LC) rates for all patients were 83.5%, 75.5%, and 52.3%, respectively. Patients with a tumor size ≤10 mm had a higher 7-year LC rate than those with a tumor size >10 mm (58.8% vs 46.6%, P = 0.054). Neck lymph node recurrence was observed in 17 patients (20%) and significantly related to the tumor size. Late toxicity of an eyelid dysfunction of grade 3 was observed in 1 patient with T3 tumor. Radiotherapy for sebaceous carcinoma of the eyelid is a reasonable alternative to surgical resection for tumors <10 mm in size with few severe complications, while larger tumors should be treated with surgery if feasible.

journal_name

J Radiat Res

journal_title

Journal of radiation research

authors

Takagawa Y,Tamaki W,Suzuki S,Inaba K,Murakami N,Takahashi K,Igaki H,Nakayama Y,Shigematsu N,Itami J

doi

10.1093/jrr/rrz046

subject

Has Abstract

pub_date

2019-10-23 00:00:00

pages

622-629

issue

5

eissn

0449-3060

issn

1349-9157

pii

5528219

journal_volume

60

pub_type

杂志文章

相关文献

JOURNAL OF RADIATION RESEARCH文献大全
  • Inter-unit variability of multi-leaf collimator parameters for IMRT and VMAT treatment planning: a multi-institutional survey.

    abstract：:Modern treatment machines have shown small inter-unit variability regarding beam data. Recently, vendor-provided average beam data, such as the Representative Beam Data (RBD) of the TrueBeam (Varian Medical Systems, Palo Alto, CA, USA), has been used for modeling of the Eclipse (Varian Medical Systems) treatment plann...

    journal_title：Journal of radiation research

    pub_type： 杂志文章,多中心研究

    doi：10.1093/jrr/rrz082

    authors： Isono M,Akino Y,Mizuno H,Tanaka Y,Masai N,Yamamoto T

    更新日期：2020-03-23 00:00:00

  • Cost-effectiveness analysis of cochlear dose reduction by proton beam therapy for medulloblastoma in childhood.

    abstract：BACKGROUND:The aim of this study is to evaluate the cost-effectiveness of proton beam therapy with cochlear dose reduction compared with conventional X-ray radiotherapy for medulloblastoma in childhood. METHODS:We developed a Markov model to describe health states of 6-year-old children with medulloblastoma after trea...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rrt112

    authors： Hirano E,Fuji H,Onoe T,Kumar V,Shirato H,Kawabuchi K

    更新日期：2014-03-01 00:00:00

  • Long-term clinical outcomes of salvage pelvic radiation therapy for oligo-recurrent pelvic lymph nodes after definitive external-beam radiation therapy for non-metastatic prostate cancer.

    abstract：:Although salvage external-beam radiation therapy (EBRT) is an attractive treatment option for pelvic lymph nodal recurrence (PeNR) in patients with prostate cancer (PCa), limited data are available regarding its long-term efficacy. This study examined the long-term clinical outcomes of patients who underwent salvage p...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rraa044

    authors： Sato GE,Aizawa R,Nakamura K,Takayama K,Inoue T,Yamasaki T,Kobayashi T,Akamatsu S,Ogawa O,Mizowaki T

    更新日期：2020-07-06 00:00:00

  • Preliminary survey of 3D image-guided brachytherapy for cervical cancer at representative hospitals in Asian countries.

    abstract：:3D image-guided brachytherapy (3D-IGBT) has become a standard therapy for cervical cancer. However, the use of 3D-IGBT is limited in East and Southeast Asia. This study aimed to clarify the current usage patterns of 3D-IGBT for cervical cancer in East and Southeast Asia. A questionnaire-based survey was performed in 1...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rraa025

    authors： Okonogi N,Wakatsuki M,Mizuno H,Fukuda S,Cao J,Kodrat H,Lau FN,Calaguas MJ,de Los Reyes RH,Chansilpa Y,Uddin AFMK,Adylkhanov T,Cho CK,Tsegmed U,Hoang NC,Ohno T,Nakano T,Kato S,Forum for Nuclear Cooperation in Asia.

    更新日期：2020-07-06 00:00:00

  • Analysis of cytogenetic damage in rice seeds induced by energetic heavy ions on-ground and after spaceflight.

    abstract：:To analyze the biological effects of the space environment, we flew nine lines of rice seeds on the Chinese 20(th) recoverable satellite for a duration of 18 days. The same lines of seeds were also irradiated to low doses (2.0 mGy) of Carbon, or Neon or Iron ions (with different LET value of 13.3 keV/microm, 31 keV/mi...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1269/jrr.0613

    authors： Wei LJ,Yang Q,Xia HM,Furusawa Y,Guan SH,Xin P,Sun YQ

    更新日期：2006-11-01 00:00:00

  • Chromosomal aberrations detected by chromosome painting in lymphocytes from cancer patients given high doses of therapeutic X-rays.

    abstract：:Chromosome painting by fluorescence in situ hybridization (FISH) with a whole chromosome-specific DNA probe was used to detect chromosomal aberrations in lymphocytes from cancer patients given partial-body fractionated X-ray therapy. Six male patients with cancer of the stomach, prostate, lung, or hepatocellular carci...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1269/jrr.37.257

    authors： Matsuoka A,Yamada K,Hayashi M,Sofuni T

    更新日期：1996-12-01 00:00:00

  • Dosimetry of mixed neutron and gamma radiation with paired Fricke solutions in light and heavy water.

    abstract：:Paired Fricke solutions, made up from light water or heavy water and 0.8N in H2SO4 and 1 mM in Fe(NH4)2(SO4)2 and NaCl, were calibrated with 60Co gamma rays and with mixed neutron and gamma radiation from a 252Cf source. Absorbance increases, AL and AH, in light- and heavy-water Fricke dosimeters, respectively, increa...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1269/jrr.37.97

    authors： Himit M,Itoh T,Endo S,Fujikawa K,Hoshi M

    更新日期：1996-06-01 00:00:00

  • Annual changes in the Fukushima residents' views on the safety of water and air environments and their associations with the perception of radiation risks.

    abstract：:Fukushima residents' negative views on the safety of water and air environments have been a concern since the Fukushima Dai-ichi Nuclear power plant (FDNPP) accident. The objective of this study was to clarify the factors determining these negative views and their association with radiation risk perception using the o...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rrx096

    authors： Suzuki S,Murakami M,Nishikiori T,Harada S

    更新日期：2018-04-01 00:00:00

  • A novel combination treatment of armed oncolytic adenovirus expressing IL-12 and GM-CSF with radiotherapy in murine hepatocarcinoma.

    abstract：:In this study, a novel combination treatment of armed oncolytic adenovirus expressing interleukin 12 (IL-12) and granulocyte-macrophage colony-stimulating factor (GM-CSF) with radiation was investigated for antitumor and antimetastatic effect in a murine hepatic cancer (HCa-I) model. Tumor bearing syngeneic mice were ...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1269/jrr.10185

    authors： Kim W,Seong J,Oh HJ,Koom WS,Choi KJ,Yun CO

    更新日期：2011-01-01 00:00:00

  • An approach to estimate radioadaptation from DSB repair efficiency.

    abstract：:In this review, we would like to introduce a unique approach for the estimation of radioadaptation. Recently, we proposed a new methodology for evaluating the repair efficiency of DNA double-strand breaks (DSB) using a model system. The model system can trace the fate of a single DSB, which is introduced within intron...

    journal_title：Journal of radiation research

    pub_type： 杂志文章,评审

    doi：10.1269/jrr.09050

    authors： Yatagai F,Sugasawa K,Enomoto S,Honma M

    更新日期：2009-09-01 00:00:00

  • Electron probe X-ray microanalysis of boar and inobuta testes after the Fukushima accident.

    abstract：:We aimed to investigate the effect of chronic radiation exposure associated with the Fukushima Daiichi Nuclear Power Plant (FNPP) accident on the testes of boar and inobuta (a hybrid of Sus scrofa and Sus scrofa domestica). This study examined the contamination levels of radioactive caesium (Cs), especially (134)Cs an...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rrv070

    authors： Yamashiro H,Abe Y,Hayashi G,Urushihara Y,Kuwahara Y,Suzuki M,Kobayashi J,Kino Y,Fukuda T,Tong B,Takino S,Sugano Y,Sugimura S,Yamada T,Isogai E,Fukumoto M

    更新日期：2015-12-01 00:00:00

  • Preliminary study on radiosensitivity to carbon ions in human breast cancer.

    abstract：:The aim of the study was to investigate the various effects of high linear energy transfer (LET) carbon ion (12C6+) and low LET X-ray radiation on MDA-MB-231 and MCF-7 human breast cancer cells and to explore the underlying mechanisms of radiation sensitivity. Cell proliferation, cell colony formation, cell cycle dist...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rraa017

    authors： Zhang Q,Kong Y,Yang Z,Liu Y,Liu R,Geng Y,Luo H,Zhang H,Li H,Feng S,Wang X

    更新日期：2020-05-22 00:00:00

  • Protective roles of bacterioruberin and intracellular KCl in the resistance of Halobacterium salinarium against DNA-damaging agents.

    abstract：:Halobacterium salinarium, a member of the extremely halophilic archaebacteria, contains a C50-carotenoid namely bacterioruberin. We have previously reported the high resistance of this organism against the lethal actions of DNA-damaging agents including ionizing radiation and ultraviolet light (UV). In this study, we ...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1269/jrr.39.251

    authors： Shahmohammadi HR,Asgarani E,Terato H,Saito T,Ohyama Y,Gekko K,Yamamoto O,Ide H

    更新日期：1998-12-01 00:00:00

  • Assignment of six patients with xeroderma pigmentosum in Hokkaido area to a variant form.

    abstract：:Six Japanese patients in Hokkaido area were diagnosed as xeroderma pigmentosum (XP) at two University Hospital; one patient, a 29 years old female (XP2AS) at Asahikawa Medical College, and five patients, namely, a 53 years old male (XP1SA), a 45 years old female (XP2SA), a 46 years old female (XP3SA), a 47 years old m...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1269/jrr.35.168

    authors： Fujikawa K,Ayaki H,Ishizaki K,Takatera H,Matsuo S,Iizuka H,Koizumi H,Ikenaga M

    更新日期：1994-09-01 00:00:00

  • 4D digitally reconstructed radiography for verifying a lung tumor position during volumetric modulated arc therapy.

    abstract：:We have proposed four dimensional (4D) digitally reconstructed radiography (DRR) for verifying a lung tumor position during volumetric modulated arc therapy (VMAT). An internal target volume (ITV) was defined based on two clinical target volumes (CTVs) delineated on maximum exhalation and maximum inhalation images acq...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rrs013

    authors： Nakagawa K,Kida S,Haga A,Masutani Y,Yamashita H,Onoe T,Imae T,Tanaka K,Ohtomo K,Yoda K

    更新日期：2012-07-01 00:00:00

  • Clinical factors related to recurrence after hepatic arterial concurrent chemoradiotherapy for advanced but liver-confined hepatocellular carcinoma.

    abstract：:Before the sorafenib era, advanced but liver-confined hepatocellular carcinoma (HCC) was treated by liver-directed therapy. Hepatic arterial concurrent chemoradiotherapy (CCRT) has been performed in our group, giving substantial local control but frequent failure. The aim of this study was to analyze patterns of failu...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rrt034

    authors： Cha H,Yoon HI,Lee IJ,Koom WS,Han KH,Seong J

    更新日期：2013-11-01 00:00:00

  • Radioprotective effect of chitosan in sub-lethally X-ray irradiated mice.

    abstract：:The radioprotective effect of chitosan was studied in mice following whole-body X-ray irradiation. C3H/He mice were exposed to 7 Gy, and their survival rates were examined. The survival rates of chitosan-diet mice were about 20% higher than those of mice on a standard diet, and the rates dropped sharply to a plateau a...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1269/jrr.44.53

    authors： Nishimura Y,Kim HS,Ikota N,Arima H,Bom HS,Kim YH,Watanabe Y,Yukawa M,Ozawa T

    更新日期：2003-03-01 00:00:00

  • Protective activity of a novel resveratrol analogue, HS-1793, against DNA damage in 137Cs-irradiated CHO-K1 cells.

    abstract：:Resveratrol has received considerable attention as a polyphenol with anti-oxidant, anti-carcinogenic, and anti-inflammatory effects. Radiation is an important component of therapy for a wide range of malignant conditions. However, it causes damage to normal cells and, hence, can result in adverse side effects. This st...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rrt140

    authors： Jeong MH,Yang KM,Jeong DH,Lee CG,Oh SJ,Jeong SK,Lee KW,Jo YR,Jo WS

    更新日期：2014-05-01 00:00:00

  • The LD50 associated with exposure to the atomic bombing of Hiroshima and Nagasaki.

    abstract：:Numerous attempts have been made to estimate the distance at which 50% of the individuals exposed to the A-bombing of Hiroshima and Nagasaki died, ostensibly from their exposure to ionizing radiation. It is difficult to convert most of these distance estimates to a dose-related LD50, since radiation shielding was igno...

    journal_title：Journal of radiation research

    pub_type： 杂志文章,评审

    doi：10.1269/jrr.32.supplement_154

    authors： Fujita S,Kato H,Schull WJ

    更新日期：1991-03-01 00:00:00

  • Consecutive CT-guided core needle tissue biopsy of lung lesions in the same dog at different phases of radiation-induced lung injury.

    abstract：:This project aimed to set up a Beagle dog model of radiation-induced lung injury in order to supply fresh lung tissue samples in the different injury phases for gene and protein research. Three dogs received 18 Gy X-ray irradiation in one fraction, another three dogs received 8 Gy in each of three fractions at weekly ...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rrw053

    authors： Yin Z,Deng S,Liang Z,Wang Q

    更新日期：2016-09-01 00:00:00

  • Development of a hybrid magnetic resonance/computed tomography-compatible phantom for magnetic resonance guided radiotherapy.

    abstract：:The purpose of the present study was to develop a hybrid magnetic resonance/computed tomography (MR/CT)-compatible phantom and tissue-equivalent materials for each MR and CT image. Therefore, the essential requirements necessary for the development of a hybrid MR/CT-compatible phantom were determined and the developme...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rrz094

    authors： Kim MJ,Lee SR,Song KH,Baek HM,Choe BY,Suh TS

    更新日期：2020-03-23 00:00:00

  • Experimental model of naturally occurring post-radiation sarcoma: interest of positron emission tomography (PET) for early detection.

    abstract：:Radiotherapy is an integral part of overall cancer therapy. One of the most serious adverse effects of irradiation concern, for long-term survivors, the development of post-radiation sarcoma (PRS) in healthy tissues located within the irradiated area. PRS have bad prognosis and are often detected at a late stage. Ther...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1269/jrr.11008

    authors： Phulpin B,Tran N,Leroux A,Poussier S,Marie PY,Pinel S,Huger S,Henrot P,Gallet P,Blaise C,Bravetti P,Graff P,Merlin JL,Dolivet G

    更新日期：2012-01-01 00:00:00

  • 3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) sensitizes mammalian cells to UV radiation by causing the S-phase arrest, not by inhibiting the repair of DNA damage as observed in Escherichia coli.

    abstract：:3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) is known to be a mutagen and carcinogen isolated from the charred parts of cooked foods. We found previously that Trp-P-1 enhanced UV-induced lethality and mutation frequency in Escherichia coli by inhibiting the repair of UV-induced DNA damage. In the present stud...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1269/jrr.39.21

    authors： Mori T,Nakagawa A,Kobayashi N,Hashimoto MW,Wakabayashi K,Shimoi K,Kinae N

    更新日期：1998-03-01 00:00:00

  • Application of a newly developed photoluminescence glass dosimeter for measuring the absorbed dose in individual mice exposed to low-dose rate 137Cs gamma-rays.

    abstract：:A photoluminescence glass dosimeter, GD-301, was applied to the measurement of low absorbed doses in mice exposed to low-dose rate 137Cs gamma-rays. The dosimeter system consists of small rod-shaped glass chip detectors capable of embedded in the body of a mouse and an automatic readout device equipped with a standard...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1269/jrr.41.129

    authors： Hoshi Y,Nomura T,Oda T,Iwasaki T,Fujita K,Ishikawa T,Kato A,Ikegami T,Sakai K,Tanooka H,Yamada T

    更新日期：2000-06-01 00:00:00

  • Effects of combined radiofrequency field exposure on amyloid-beta-induced cytotoxicity in HT22 mouse hippocampal neurones.

    abstract：:Alzheimer's disease (AD) is the most common progressive and irreversible neurodegenerative disease and it is caused by neuronal death in the brain. Recent studies have shown that non-ionizing radiofrequency (RF) radiation has some beneficial cognitive effects in animal models of AD. In this study, we examined the effe...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rrw040

    authors： Lee JS,Kim JY,Kim HJ,Kim JC,Lee JS,Kim N,Park MJ

    更新日期：2016-11-01 00:00:00

  • PU-H71, a novel Hsp90 inhibitor, as a potential cancer-specific sensitizer to carbon-ion beam therapy.

    abstract：:PU-H71, a heat shock protein 90 (Hsp90) inhibitor, has yielded therapeutic efficacy in many preclinical models and is currently in clinical trials. Carbon-ion radiotherapy (CIRT) has provided successful tumor control; however, there is still room for improvement, particularly in terms of tumor-specific radiosensitizat...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rrw054

    authors： Li HK,Matsumoto Y,Furusawa Y,Kamada T

    更新日期：2016-09-01 00:00:00

  • Radiation carcinogenesis in dogs irradiated during prenatal and postnatal development.

    abstract：:To evaluate the lifetime hazards of ionizing radiation exposure, 1680 beagles received whole-body, 60-Cobalt gamma exposures or sham-exposures during development. Eight groups of 120 dogs each received mean doses of 16 or 83 cGy at 8 (preimplantation), 28 (embryonic), or 55 (late fetal) days postcoitus (dpc), or 2 (ne...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1269/jrr.32.supplement2_86

    authors： Benjamin SA,Saunders WJ,Angleton GM,Lee AC

    更新日期：1991-12-01 00:00:00

  • The role of interleukin-13 in the removal of hyper-radiosensitivity by priming irradiation.

    abstract：:It has previously been demonstrated that the presence of fetal bovine serum is necessary for TGF-β3 (transforming growth factor beta 3)-dependent elimination of low-dose hyper-radiosensitivity (HRS) in cells by 1 h of low-dose-rate γ-irradiation (0.2-0.3 Gy/h). The purpose of the present study was to identify the seru...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rru053

    authors： Edin NF

    更新日期：2014-11-01 00:00:00

  • Effect of gamma-irradiation on the uptake and digestion of 125I-labeled bovine serum albumin by rat visceral yolk sac cultured in vitro.

    abstract：:The effect of gamma-irradiation on a major nutritional function of the yolk sac (the uptake and digestion of macromolecular materials) was studied in rat visceral yolk sacs cultured in vitro being used 125I-labeled bovine serum albumin (RISA) as the tracer protein. The uptake of RISA (per g wet weight) by rat yolk sac...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1269/jrr.34.171

    authors： Takahashi S,Koshimoto C,Kubota Y

    更新日期：1993-06-01 00:00:00

  • Dosimetric comparison between volumetric modulated arc therapy planning techniques for prostate cancer in the presence of intrafractional organ deformation.

    abstract：:The purpose of this study was to compare single-arc (SA) and double-arc (DA) treatment plans, which are planning techniques often used in prostate cancer volumetric modulated arc therapy (VMAT), in the presence of intrafractional deformation (ID) to determine which technique is superior in terms of target dose coverag...

    journal_title：Journal of radiation research

    pub_type： 杂志文章

    doi：10.1093/jrr/rraa123

    authors： Varnava M,Sumida I,Oda M,Kurosu K,Isohashi F,Seo Y,Otani K,Ogawa K

    更新日期：2020-12-21 00:00:00