Abstract:
:Previous studies on crossmodal spatial orienting typically used simple and stereotyped stimuli in the absence of any meaningful context. This study combined computational models, behavioural measures and functional magnetic resonance imaging to investigate audiovisual spatial interactions in naturalistic settings. We created short videos portraying everyday life situations that included a lateralised visual event and a co-occurring sound, either on the same or on the opposite side of space. Subjects viewed the videos with or without eye-movements allowed (overt or covert orienting). For each video, visual and auditory saliency maps were used to index the strength of stimulus-driven signals, and eye-movements were used as a measure of the efficacy of the audiovisual events for spatial orienting. Results showed that visual salience modulated activity in higher-order visual areas, whereas auditory salience modulated activity in the superior temporal cortex. Auditory salience modulated activity also in the posterior parietal cortex, but only when audiovisual stimuli occurred on the same side of space (multisensory spatial congruence). Orienting efficacy affected activity in the visual cortex, within the same regions modulated by visual salience. These patterns of activation were comparable in overt and covert orienting conditions. Our results demonstrate that, during viewing of complex multisensory stimuli, activity in sensory areas reflects both stimulus-driven signals and their efficacy for spatial orienting; and that the posterior parietal cortex combines spatial information about the visual and the auditory modality.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Nardo D,Santangelo V,Macaluso Edoi
10.1002/hbm.22276subject
Has Abstractpub_date
2014-04-01 00:00:00pages
1597-614issue
4eissn
1065-9471issn
1097-0193journal_volume
35pub_type
杂志文章abstract::The dynamics of the human brain span multiple spatial scales, from connectivity associated with a specific region/network to the global organization, each representing different brain mechanisms. Yet brain reconfigurations at different spatial scales are seldom explored and whether they are associated with the neural ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25205
更新日期:2021-01-01 00:00:00
abstract::Fast cancellation or switching of action plans is a critical cognitive function. Rapid signal transmission is key for quickly executing and inhibiting responses, and the structural integrity of connections between brain regions plays a crucial role in signal transmission speed. In this study, we used the search-step t...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23209
更新日期:2016-08-01 00:00:00
abstract::The dorsal attention network (DAN), including frontal eye fields and posterior parietal cortices, and its link with the posterior thalamus, contribute to visual-spatial abilities. Very premature birth impairs both visual-spatial abilities and cortico-thalamic structural connectivity. We hypothesized that impaired stru...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24685
更新日期:2019-10-01 00:00:00
abstract::Movement execution strongly relies on precise sensorimotor synchronization. In a finger-tapping task that requires subjects to synchronize their finger taps to regular pacing signal synchronization accuracy varies with respect to pacing signal's modality. This study aimed at elucidating functional brain dynamics assoc...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20762
更新日期:2009-06-01 00:00:00
abstract::The description of brain networks as graphs where nodes represent different brain regions and edges represent a measure of connectivity between a pair of nodes is an increasingly used approach in neuroimaging research. The development of powerful methods for edge-wise group-level statistical inference in brain graphs ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24007
更新日期:2018-06-01 00:00:00
abstract::Simultaneous electroencephalogram/functional magnetic resonance imaging (EEG-fMRI) during interictal epileptiform discharges can result in positive (activation) and negative (deactivation) changes in the blood oxygenation level-dependent (BOLD) signal. Activation probably reflects increased neuronal activity and energ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20193
更新日期:2006-06-01 00:00:00
abstract::Multicenter structural MRI studies can have greater statistical power than single-center studies. However, across-center differences in contrast sensitivity, spatial uniformity, etc., may lead to tissue classification or image registration differences that could reduce or wholly offset the enhanced statistical power o...
journal_title:Human brain mapping
pub_type: 杂志文章,多中心研究
doi:10.1002/hbm.20991
更新日期:2010-12-01 00:00:00
abstract::Prior neuroimaging studies support the hypothesis that anticipation, an important component of anxiety, may be mediated by activation within the insular and medial prefrontal cortices including the anterior cingulate cortex. However, there is an insufficient understanding of how affective anticipation differs across a...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21154
更新日期:2011-11-01 00:00:00
abstract::Fetal alcohol spectrum disorders comprise the spectrum of cognitive, behavioral, and neurological impairments caused by prenatal alcohol exposure (PAE). Diffusion tensor imaging (DTI) was performed on 54 children (age 10.1 ± 1.0 years) from the Cape Town Longitudinal Cohort, for whom detailed drinking histories obtain...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23218
更新日期:2016-08-01 00:00:00
abstract::Fluid intelligence (gf) refers to abstract reasoning and problem solving abilities. It is considered a human higher cognitive factor central to general intelligence (g). The regions of the cortex supporting gf have been revealed by recent bioimaging studies and valuable hypothesis on the neural correlates of individua...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20519
更新日期:2009-02-01 00:00:00
abstract::This paper describes a Bayesian method for three-dimensional registration of brain images. A finite element approach is used to obtain a maximum a posteriori estimate of the deformation field at every voxel of a template volume. The priors used by the MAP estimate penalize unlikely deformations and enforce a continuou...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(sici)1097-0193(200004)9:4<212::aid-hbm3>3
更新日期:2000-04-01 00:00:00
abstract::Coordinate-based, voxel-wise meta-analysis is an exciting recent addition to the human functional brain mapping literature. In view of the critical importance of selection criteria for any valid meta-analysis, a taxonomy of experimental design should be an important tool for aiding in the design of rigorous meta-analy...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20141
更新日期:2005-05-01 00:00:00
abstract::Huntington disease (HD) is a neurodegenerative disorder that involves preferential atrophy in the striatal complex and related subcortical nuclei. In this article, which is based on a dataset extracted from the PREDICT-HD study, we use statistical shape analysis with deformation markers obtained through "Large Deforma...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22214
更新日期:2014-03-01 00:00:00
abstract::Synchrony measurements of spontaneous low-frequency blood oxygenation level-dependent (BOLD) fluctuations are increasingly being used to investigate spatial regions of functional connectivity. Although information regarding BOLD-BOLD synchrony between different regions is frequently reported, the relationship between ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21228
更新日期:2012-03-01 00:00:00
abstract::Adaptive behavior relies on the ability of the brain to form predictions and monitor action outcomes. In the human brain, the same system is thought to monitor action outcomes regardless of whether the information originates from internal (e.g., proprioceptive) and external (e.g., visual) sensory channels. Neural sign...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24273
更新日期:2018-11-01 00:00:00
abstract::The registration of image volumes derived from different imaging modalities such as MRI, PET, SPECT, and CT has been described in numerous studies in which functional and morphological data are combined on the basis of macrostructural information. However, the exact topography of architectural details is defined by mi...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The origin, structure, and function of the claustrum, as well as its role in neural computation, have remained a mystery since its discovery in the 17th century. Assessing the in vivo connectivity of the claustrum may bring forth useful insights with relevance to model the overall functionality of the claustrum itself...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22667
更新日期:2015-03-01 00:00:00
abstract::Humans can easily recognize others' facial expressions. Among the brain substrates that enable this ability, considerable attention has been paid to face-selective areas; in contrast, whether motion-sensitive areas, which clearly exhibit sensitivity to facial movements, are involved in facial expression recognition re...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23578
更新日期:2017-06-01 00:00:00
abstract::In BOLD fMRI data analysis, robust and accurate estimation of the Hemodynamic Response Function (HRF) is still under investigation. Parametric methods assume the shape of the HRF to be known and constant throughout the brain, whereas non-parametric methods mostly rely on artificially increasing the signal-to-noise rat...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10100
更新日期:2003-05-01 00:00:00
abstract::Theoretical models of addiction suggest that a substance use disorder represents an imbalance between hypersensitive motivational processes and deficient regulatory executive functions. Working-memory (a central executive function) may be a powerful predictor of the course of drug use and drug-related problems. Goal o...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22342
更新日期:2014-05-01 00:00:00
abstract::How the human brain represents distinct motor features into a unique finalized action still remains undefined. Previous models proposed the distinct features of a motor act to be hierarchically organized in separated, but functionally interconnected, cortical areas. Here, we hypothesized that distinct patterns across ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22881
更新日期:2015-10-01 00:00:00
abstract::Hypercoupling of activity in speech-perception-specific brain networks has been proposed to play a role in the generation of auditory-verbal hallucinations (AVHs) in schizophrenia; however, it is unclear whether this hypercoupling extends to nonverbal auditory perception. We investigated this by comparing schizophreni...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23934
更新日期:2018-04-01 00:00:00
abstract::Individual differences in general cognitive ability (i.e., intelligence) have been linked to individual variations in the modular organization of functional brain networks. However, these analyses have been limited to static (time-averaged) connectivity, and have not yet addressed whether dynamic changes in the config...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24807
更新日期:2020-02-01 00:00:00
abstract::We used emotional expectancy to study attentional modulation in the processing of emotional stimuli. During functional magnetic resonance imaging (fMRI), volunteers saw emotional and neutral expectancy cues signaling the subsequent presentation of corresponding emotional or neutral pictorial stimuli. As a control, emo...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20209
更新日期:2006-08-01 00:00:00
abstract:INTRODUCTION:Cortical thickness mapping is a widely used method for the analysis of neuroanatomical differences between subject groups. We applied power analysis methods over a range of image processing parameters to derive a model that allows researchers to calculate the number of subjects required to ensure a well-po...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22120
更新日期:2013-11-01 00:00:00
abstract::Months, days of the week, and numbers differ from other verbal concepts because they are ordered in a sequence, whereas no order is imposed on members of other categories, such as animals or tools. Recent studies suggest that numbers activate a representation of their quantity within the intraparietal sulcus (IPS) aut...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20433
更新日期:2008-08-01 00:00:00
abstract::When ambiguous visual stimuli have multiple interpretations, human perception can alternate between them, producing perceptual multistability. There is a large variation between individuals in how long stable percepts endure, on average, between switches, but the underlying neural basis of this individual difference i...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24533
更新日期:2019-06-01 00:00:00
abstract::We describe a method for the statistical parametric mapping of low resolution electromagnetic tomography (LORETA) using high-density electroencephalography (EEG) and individual magnetic resonance images (MRI) to investigate the characteristics of the mismatch negativity (MMN) generators in schizophrenia. LORETA, using...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10059
更新日期:2002-11-01 00:00:00
abstract::During the developmental stage, the brain undergoes anatomic, functional, and metabolic changes necessary to support the complex adaptive behavior of a mature individual. Estimation of developmental changes occurring in different regions of the brain would provide a means of relating various behavioral phenomena to ma...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20020
更新日期:2004-06-01 00:00:00
abstract::Constrained spherical deconvolution (CSD) of diffusion-weighted MRI (DW-MRI) is a popular analysis method that extracts the full white matter (WM) fiber orientation density function (fODF) in the living human brain, noninvasively. It assumes that the DW-MRI signal on the sphere can be represented as the spherical conv...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25241
更新日期:2020-11-10 00:00:00