An outbreak of hepatitis A in young adults in central Italy.

Abstract:

:Between September, 1988 and January, 1989 a common source outbreak of 47 cases of serologically confirmed hepatitis A occurred in a town of central Italy. Thirty-eight cases were primary, three co-primary and six secondary. The highest age-specific attack rate was seen in subjects aged 15-24 years (120 per 100,000); the mean age of cases was 24.6 years and the median age was 22 years. A matched triplet case-control study showed significant association between the disease and consumption of either raw mussels (41% of cases, compared with 10% of controls; P less than 0.0001) or a single brand of mineral water (63% of cases, compared with 41% of controls; P less than 0.05). The mean age of the cases reflects the shift in primary susceptibility to the infection from younger to older age groups, a finding which has recently been demonstrated by several seroepidemiological surveys in Italy.

journal_name

Eur J Epidemiol

authors

Stroffolini T,Biagini W,Lorenzoni L,Palazzesi GP,Divizia M,Frongillo R

doi

10.1007/BF00145788

subject

Has Abstract

pub_date

1990-06-01 00:00:00

pages

156-9

issue

2

eissn

0393-2990

issn

1573-7284

journal_volume

6

pub_type

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