Abstract:
:The Longitudinal Aging Study Amsterdam (LASA) is a prospective cohort study of older adults in the Netherlands, initially based on a nationally representative sample of people aged 55-84 years. The study has been ongoing since 1992, and focuses on the determinants, trajectories and consequences of physical, cognitive, emotional and social functioning. Strengths of the LASA study include its multidisciplinary character, the availability of over 25 years of follow-up, and the cohort-sequential design that allows investigations of longitudinal changes, cohort differences and time trends in functioning. The findings from LASA have been reported in over 600 publications so far (see www.lasa-vu.nl). This article provides an update of the design of the LASA study and its methods, on the basis of recent developments. We describe additional data collections, such as additional nine-monthly measurements in-between the regular three-yearly waves that have been conducted among the oldest old during 2016-2019, and the inclusion of a cohort of older Turkish and Moroccan migrants.
journal_name
Eur J Epidemioljournal_title
European journal of epidemiologyauthors
Hoogendijk EO,Deeg DJH,de Breij S,Klokgieters SS,Kok AAL,Stringa N,Timmermans EJ,van Schoor NM,van Zutphen EM,van der Horst M,Poppelaars J,Malhoe P,Huisman Mdoi
10.1007/s10654-019-00541-2subject
Has Abstractpub_date
2020-01-01 00:00:00pages
61-74issue
1eissn
0393-2990issn
1573-7284pii
10.1007/s10654-019-00541-2journal_volume
35pub_type
杂志文章abstract:BACKGROUND:The relationships between body size and fatness and blood pressure are generally acknowledged. The majority of the few studies that have examined the effect of fat distribution and maturation rate on blood pressure have used secondary sex characteristics as the measure of maturity. The aim of the present stu...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1021220814413
更新日期:2001-01-01 00:00:00
abstract::The clinical course of chronic hepatitis C (CHC) is generally asymptomatic in children. The aim of this study was to examine the influence of HCV RNA in peripheral blood mononuclear cells (PBMCs) on the clinical course of CHC considering age at the time of infection, length of infection, hepatitis virus C (HCV) genoty...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-007-9125-2
更新日期:2007-01-01 00:00:00
abstract::Human anthrax vaccines currently licensed in the United States and Western Europe consist of alum-precipitated or aluminum hydroxide-adsorbed supernatant material from fermentor cultures of toxigenic, nonencapsulated strains of Bacillus anthracis. These vaccines have several drawbacks, including the need for frequent ...
journal_title:European journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1007/BF00152686
更新日期:1988-03-01 00:00:00
abstract::We investigated whether coffee consumption was associated with all-cause, cancer, or cardiovascular mortality in a prospective cohort of 49,259 Swedish women. Of the 1576 deaths that occurred in the cohort, 956 were due to cancer and 158 were due to cardiovascular disease. We used Cox proportional hazard models with a...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-015-0052-3
更新日期:2015-09-01 00:00:00
abstract::We compared blood pressure of individuals (mean age 59 y) born in western Holland between January 1945 and March 1946 (mothers exposed to the Dutch Famine before or during gestation; n = 359) to blood pressure of unexposed individuals born before or conceived after the famine (n = 299) or same-sex siblings of subjects...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-006-9065-2
更新日期:2006-01-01 00:00:00
abstract::Lower respiratory tract infections (LRTIs) are a major cause of hospitalization in infants. Research suggests that immunomodulatory properties of vitamin D may influence LRTI risk. This study's objective was to examine whether 25-hydroxyvitamin D [25(OH)D] concentrations in cord blood influenced susceptibility to LRTI...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-014-9918-z
更新日期:2014-08-01 00:00:00
abstract::In this matched-pair study 139 pregnant women were matched on the basis of age to an equal number of non-pregnant women with no signs of genital infection. The mean age was 28.7 years (range 20-41). The cut-offs used for detection of chlamydial antibody were 1:64 and 1:128 for IgG and 1:16 for IgA. IgG antibody at 64 ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF01717451
更新日期:1994-02-01 00:00:00
abstract:OBJECTIVE:Self-rated health (SRH) is widely used to compare population health across countries, but comparability is often hampered by the use of different versions of this item. This study compares the WHO recommended version (ranging from 'very good' to 'very bad') with the US version (ranging from 'excellent' to 'po...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-008-9287-6
更新日期:2008-01-01 00:00:00
abstract::Insulin resistance, low HDL-cholesterol and microalbuminuria are important components of the metabolic syndrome as defined by WHO. Insulin resistance and low HDL-cholesterol are also common in chronic kidney disease (CKD), but it is not clear whether they are early or late phenomenons in the development of renal failu...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-007-9164-8
更新日期:2007-01-01 00:00:00
abstract::The Rotterdam Study is an ongoing prospective cohort study that started in 1990 in the city of Rotterdam, The Netherlands. The study aims to unravel etiology, preclinical course, natural history and potential targets for intervention for chronic diseases in mid-life and late-life. The study focuses on cardiovascular, ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-020-00640-5
更新日期:2020-05-01 00:00:00
abstract::The rapid and continuing progress in gene discovery for complex diseases is fuelling interest in the potential application of genetic risk models for clinical and public health practice. The number of studies assessing the predictive ability is steadily increasing, but they vary widely in completeness of reporting and...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-011-9551-z
更新日期:2011-04-01 00:00:00
abstract::The last case of poliomyelitis due to transmission of indigenous wild poliovirus occurred in Italy in 1982. To achieve the certification of the eradication of poliomyelitis in Italy, an active surveillance of acute flaccid paralysis (AFP) in the population aged less than 15 years was set up following the World Health ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1007697421114
更新日期:1999-09-01 00:00:00
abstract::We describe a material of 577 infants born of epileptic women treated with anticonvulsants in monotherapy during early pregnancy and collected from France, Italy, and Sweden. The incidence of major malformations is increased compared with the general population but no definite difference in risk can be demonstrated be...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00239754
更新日期:1987-06-01 00:00:00
abstract::In order to evaluate the AIDS related sources of information, knowledge, attitudes and behaviours among male young people it was filled in a multi-choice anonymous questionnaire by 2018 subjects, called for the first medical examination to Italian Navy and by 1348 recruits. The data from the latter group were used to ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF01719942
更新日期:1995-02-01 00:00:00
abstract::We discuss the analytic and practical considerations in a large case-control study that had two control groups; the first control group consisting of partners of patients and the second obtained by random digit dialling (RDD). As an example of the evaluation of a general lifestyle factor, we present body mass index (B...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-010-9475-z
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:In epidemiological studies abundant physical activity has been related to decreased breast cancer risk, though the results have been inconsistent. The purpose of this paper was to study the association of physical activity at leisure and commuting to work and incidence of breast cancer. METHODS:The study co...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1010847311422
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Pregnancy and use of combined oral contraceptives (COCs) are major risk factors for venous thromboembolism (VTE) in young women and we wanted to obtain accurate VTE mortality data overall, by age, associated with the use of COCs and pregnancy. METHODS:From the Swedish Cause of Death Register (CDR) we identi...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-005-4266-7
更新日期:2005-01-01 00:00:00
abstract::In order to investigate the shift in the rates and levels of antibody to hepatitis A virus, 567 children in 20 isolated groups of five day-care centers were observed over a period of 8 months during which the seasonal rise in hepatitis A morbidity occurs. Increases in the proportion of seropositive ranging from 5 to 3...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00145647
更新日期:1987-12-01 00:00:00
abstract::The Generation R Study is a population-based prospective cohort study from fetal life until adulthood. The study is designed to identify early environmental and genetic causes and causal pathways leading to normal and abnormal growth, development and health from fetal life, childhood and young adulthood. This multidis...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-016-0224-9
更新日期:2016-12-01 00:00:00
abstract::The authors report and discuss the characteristics of 22 women who discovered their HIV seropositivity while pregnant. Most of the women had never been tested for HIV and this occurred not only for 'not at risk' women but also for sexual partners of HIV-infected men. Several infections were diagnosed late in pregnancy...
journal_title:European journal of epidemiology
pub_type: 信件
doi:10.1023/b:ejep.0000024782.09206.c8
更新日期:2004-01-01 00:00:00
abstract::Data regarding 11,541 cases of school accidents (from kindergarten to senior high school) that required hospital attention for treatment were examined. The information was obtained from the records of the "School Medicine Service of the City of Milan", and covered five school years (from 1980-81 to 1984-85). The surve...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00239759
更新日期:1987-06-01 00:00:00
abstract::The titres of antibody to hepatitis A virus (anti-HAV) were found to fall rapidly during 3-4 years after hepatitis A and more slowly thereafter, though they never reached undetectable levels in at least 23 years. The levels of anti-HAV in convalescents after overt hepatitis A were found to be significantly much higher...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00152715
更新日期:1986-03-01 00:00:00
abstract::We tested the hypothesis of an association between childhood type 1 diabetes (T1D) risk and nitrate concentration in drinking water in Sardinia, Italy, using Poisson regression analysis. Childhood T1D risk showed an inverse trend with increasing quartile of nitrate level in the total population and among men. A nitrat...
journal_title:European journal of epidemiology
pub_type: 信件
doi:10.1007/s10654-006-0014-x
更新日期:2006-01-01 00:00:00
abstract::The aetiology of childhood cancers remains largely unknown. Space-time clustering of cases might imply an aetiological role of infections. We aimed to review the evidence of space-time clustering of specific childhood cancers. We searched Medline and Embase for population-based studies that covered a pre-defined study...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-018-0456-y
更新日期:2019-01-01 00:00:00
abstract::Evidence that childbearing is associated with future development of diabetes remains conflicting and the role of pregnancy loss in this association has not been investigated. We aimed to examine whether pregnancy and/or pregnancy loss (miscarriage, abortion, or stillbirth) are associated with maternal higher risk of d...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-012-9683-9
更新日期:2012-05-01 00:00:00
abstract::Sample surveys are used to investigate occurrence and determinants of diseases in populations. Their reliability is influenced by quality of sampling frame and response rate. We investigated relationship between sampling frame type and response rates and assessed their impact on non-response bias, using data from the ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-005-0600-3
更新日期:2005-01-01 00:00:00
abstract::Neuroimaging plays an important role in etiologic research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to unravel causes of neurological disease by performing neuroimaging in a population-based longitudinal setting. In 1995 and 199...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-011-9624-z
更新日期:2011-10-01 00:00:00
abstract::The aim of our study was to assess the association between green tea consumption and all-cause and cause-specific mortality in a pooled analysis of eight Japanese population-based cohort studies. Pooled hazard ratios (HR) and 95% confidence intervals (CI), derived from random effects models, were used to evaluate the ...
journal_title:European journal of epidemiology
pub_type: 杂志文章,meta分析
doi:10.1007/s10654-019-00545-y
更新日期:2019-10-01 00:00:00
abstract::The follow-up of the French cohort of uranium miners has been extended to 1994, and a new source of information for causes of death has been used. The paper presents the new results regarding the risk of death among the cohort, and analyses the impact of the methodological changes on these results. The extension of th...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/b:ejep.0000017824.38966.01
更新日期:2004-01-01 00:00:00
abstract::This case-control study comprised 100 histologically verified laryngeal cancer patients and 100 hospital controls matched with cases by sex, age and place of residence. The following variables were tested for their association with cancer of the larynx: marital status, educational level, hard liquor consumption, cigar...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF01721228
更新日期:1995-08-01 00:00:00