Abstract：
:The follow-up of the French cohort of uranium miners has been extended to 1994, and a new source of information for causes of death has been used. The paper presents the new results regarding the risk of death among the cohort, and analyses the impact of the methodological changes on these results. The extension of the follow-up results in a substantial increase in statistical power compared with previous analysis (+25% for person-years and +74% for the number of deaths). The use of the National Mortality Database as the principal source for causes of death allows to reduce the potential bias in the calculation of standardized mortality ratios (SMR). As a consequence, an excess risk of deaths from laryngeal cancer, suggested in the first analysis, is not confirmed. The analysis shows the existence of an excess risk of deaths from lung cancer among French uranium miners (85 observed deaths, SMR = 1.9, 95% confidence interval CI: 1.5-2.3), and an increase of this risk with cumulative exposure to radon (excess relative risk per 100 working level month = 0.6, 95% CI: 0.1-1.2). These results confirm the existence of a risk of death from lung cancer in a population chronically exposed to relatively low levels of radon.
journal_name
Eur J Epidemioljournal_title
European journal of epidemiologyauthors
Laurier D,Tirmarche M,Mitton N,Valenty M,Richard P,Poveda S,Gelas JM,Quesne Bdoi
10.1023/b:ejep.0000017824.38966.01keywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
139-46issue
2eissn
0393-2990issn
1573-7284journal_volume
19pub_type
杂志文章abstract：:Although elevated serum uric acid has been associated with an increased risk of cardiovascular disease, its importance as a risk factor is still controversial. The authors examined the relationship between serum uric acid levels and death from all causes, including cardiovascular disease and stroke. The baseline data ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
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journal_title：European journal of epidemiology
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pub_type： 杂志文章
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
pub_type： 杂志文章,评审
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
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更新日期：2005-01-01 00:00:00
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007535722726
更新日期：1999-02-01 00:00:00
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00156833
更新日期：1989-06-01 00:00:00
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doi：10.1007/BF00158782
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journal_title：European journal of epidemiology
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doi：10.1007/BF00463088
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
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pub_type： 信件
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journal_title：European journal of epidemiology
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pub_type： 临床试验,杂志文章,多中心研究
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abstract：:Previously published studies on the risk of cancer among male priests have been based on cancer mortality with the exception of one case-control study. The aim of this study was to present estimates of cancer incidence among Nordic male priests. The study cohort for our analyses consisted of 6.5 million men aged 30-64...
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更新日期：2012-02-01 00:00:00
