Abstract:
:To estimate the prevalence of infection by hepatitis C virus (HCV) in general practice, and to investigate attitudes to screening for HCV, a specific questionnaire was sent to the sentinel general practitioners (SGPs) of the French Sentinel Network. From the figures reported by SGPs, the number of anti-HCV tests performed in general practice during the six months before the survey (July December 1994) was extrapolated to about 350,000 tests for the whole of France during all of 1994 (95% CI: 314,000 382.000). Of the 312 participating SGPs, 224 (72%) had prescribed at least one anti-HCV test during these six months. and 217 (70%) knew of at least one anti-HCV-positive patient in their practice. With regard to their screening attitudes. 244 SGPs (78%) said they had prescribed anti-HCV tests for patients with no signs of previous or recent hepatitis infection; SGPs who had at least two HCV-positive patients in their practice were more likely to screen for anti-HCV than SGPs who did not (94% vs. 72%, p < 0.001). The main reason for prescription were that patients had an anti-HIV-positive status, were intravenous drug users and/or were blood transfusion recipients. For the 88 SGPs who had not prescribed any anti-HCV test during the six months before the study, the main reasons given were that few patients were at risk in their practice (81 SGPs) and that the risk factors for HCV infection were not well known (12 SGPs). Only 6 SGPs gave the absence of effective treatment as a reason for non-prescription. From the figures reported by SGPs, we extrapolated to 100,000 (95% CI: 90,000-110.000) the number of anti-HCV-positive patients known by the 52,000 French general practitioners in 1994. These results indicate that the Sentinel network may be a useful tool for assessing the evolution of attitudes to HCV screening in general practice.
journal_name
Eur J Epidemioljournal_title
European journal of epidemiologyauthors
Massari V,Retel O,Flahault Adoi
10.1023/a:1007535722726keywords:
subject
Has Abstractpub_date
1999-02-01 00:00:00pages
119-24issue
2eissn
0393-2990issn
1573-7284journal_volume
15pub_type
杂志文章abstract::During the period of 1975-1989, in the Belgrade population increasing mortality trends were established for colon and rectal cancer, cancer of the pancreas and gallbladder and bile ducts cancer, for both sexes, and for esophageal cancer in males. Stomach and liver cancer mortality decreased in females. In males, stoma...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF01717461
更新日期:1994-02-01 00:00:00
abstract::Several lines of evidence point to a possible relationship between vitamin D and cardiovascular disease. Animal experiments and observational studies in humans suggest vitamin D to be arteriotoxic and an association of high intake of vitamin D with increased incidence of ischemic heart disease (IHD). The major source ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1014559600042
更新日期:2001-01-01 00:00:00
abstract::Using a computer simulation for a series of births subject to various congenital malformations, the surveillance performance of the Multicommunity Sets Technique (MST) was compared to that of the Cumulative Sum Technique (CUSUM). Increases in malformation frequencies were simulated in (i) 6 out of 6 centres and (ii) o...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00152719
更新日期:1986-03-01 00:00:00
abstract::The authors studied a population of 5634 students from various continents to determine possible correlations between risk factors and seroprevalence of HIV infection. In the African sample the seroprevalence rate was 3.5%; the age range from 19 to 30 years was most affected; prevalence differences between the sexes we...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1007635104096
更新日期:2000-02-01 00:00:00
abstract::Recent epidemiological studies have suggested passive smoking as possible risk factors in breast cancer etiology. However, the evidence is not conclusive. We conducted a meta-analysis of the risk of breast cancer associated with passive smoking. Eleven studies were identified through Medline, Cancer Abstracts and abst...
journal_title:European journal of epidemiology
pub_type: 杂志文章,meta分析
doi:10.1023/a:1010967513957
更新日期:2000-01-01 00:00:00
abstract::Stroke incidence rates have decreased in developed countries over the past 40 years, but trends vary across populations. We investigated whether age-and-sex-specific stroke incidence rates and associated risk factors as well as preventive medication use have changed in Rotterdam in the Netherlands during the last two ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-012-9673-y
更新日期:2012-04-01 00:00:00
abstract::Prenatal diagnosis performed by ultrasound scan is now a routine part of antenatal care in our region. How many fetal anomalies are actually detected by this procedure? We have used our registry of congenital malformations to answer this question regarding to Internal Urinary System (IUS) anomalies. The mean time of d...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF01719432
更新日期:1995-06-01 00:00:00
abstract::Infectious etiologies have been hypothesized for acute leukemias because of their high incidence in early childhood, but have seldom been examined for acute myeloid leukemia (AML). We conducted the first large cohort study to examine perinatal factors including season of birth, a proxy for perinatal infectious exposur...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-015-0063-0
更新日期:2015-12-01 00:00:00
abstract::To study the association between postmenopausal hormone therapy (PMH) use and the risk of rheumatoid arthritis (RA) stratifying the cases by the presence/absence of antibodies against citrullinated peptides (ACPA). A subset of the Epidemiological Investigation of RA (EIRA), a population-based case-control study, compr...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-015-0004-y
更新日期:2015-05-01 00:00:00
abstract::We carried out an epidemiological study on 2717 patients seen on a regular basis at Italian Cystic Fibrosis Centers with the aim of defining the prevalence of multiresistant Gram-negative strains in Italy. We found 272 multiresistant strains out of 1560 Gram-negative strains isolated in 1012 Italian cystic fibrosis pa...
journal_title:European journal of epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1023/a:1007504524034
更新日期:1999-01-01 00:00:00
abstract::Evidence of an association between early pregnancy exposure to selective serotonin reuptake inhibitors (SSRI) and congenital heart defects (CHD) has contributed to recommendations to weigh benefits and risks carefully. The objective of this study was to determine the specificity of association between first trimester ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-015-0065-y
更新日期:2015-11-01 00:00:00
abstract::Early life is an important window of opportunity to improve health across the full lifecycle. An accumulating body of evidence suggests that exposure to adverse stressors during early life leads to developmental adaptations, which subsequently affect disease risk in later life. Also, geographical, socio-economic, and ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-020-00662-z
更新日期:2020-07-01 00:00:00
abstract::The most common diseases affecting middle-aged and elderly subjects in industrialized countries are multigenetic and lifestyle related. Several attempts have been made to study interactions between genes and lifestyle factors, but most such studies lack the power to examine interactions between several genes and sever...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-013-9787-x
更新日期:2013-02-01 00:00:00
abstract::In high income countries females outlive men, although they generally report worse health, the so-called male-female health-survival paradox. Russia has one of the world's largest sex difference in life expectancy with a male disadvantage of more than 10 years. We compare components of the paradox between Denmark and ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-014-9893-4
更新日期:2014-04-01 00:00:00
abstract::To examine whether a low socio-economic status (SES) is an additional risk factor for glucose intolerance in Hong Kong Chinese with known risk factors for glucose intolerance, a total of 2847 Chinese subjects (473 men and 2374 women) were recruited from the community for assessment. They had known risk factors for glu...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1017935707807
更新日期:2001-01-01 00:00:00
abstract::The immune response involved in each phase of type 2 diabetes (T2D) development might be different. We aimed to identify novel inflammatory markers that predict progression from normoglycemia to pre-diabetes, incident T2D and insulin therapy. We used plasma levels of 26 inflammatory markers in 971 subjects from the Ro...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-017-0236-0
更新日期:2017-03-01 00:00:00
abstract::No population-based study has assessed the prognostic impact on survival of the CD19 positive lymphocyte count, evaluated by immunophenotyping at diagnosis, in B-cell chronic lymphocytic leukemia (B-CLL). Aiming at addressing this issue, we investigated the clinical outcome of a well-defined population of B-CLL patien...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-005-3777-6
更新日期:2005-01-01 00:00:00
abstract::The aims of the NYU Children's Health and Environment Study (CHES) are to evaluate influences of prenatal non-persistent chemical exposures on fetal and postnatal growth and pool our data with the US National Institutes of Health Environmental influences on Child Health Outcomes (ECHO) Program to answer collaborative ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-020-00623-6
更新日期:2020-03-01 00:00:00
abstract::Cardiovascular diseases (CVD) are the leading cause of premature death and disability in the developed world. Broad consensus exists on CVD preventability through reduction of their risk factors at both the individual and population level. The latter kind of intervention implies involvement of policy-making institutio...
journal_title:European journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1007/BF01719298
更新日期:1995-10-01 00:00:00
abstract::Cystinuria is an autosomal recessive disorder of the kidneys and small intestine, affecting a luminal transport mechanism shared by cystine, ornithine, arginine and lysine. When cystine exceeds its solubility at low pH, the risk of stone formation increases. The data reported in the literature show a variation for the...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1007522215041
更新日期:1999-08-01 00:00:00
abstract::The objective of this study was to evaluate the association between number of missing teeth and all cause, cardiovascular, and cancer mortality as well as morbidity and to explore whether socio-economic factors mediate this association. An ongoing prospective cohort study of 1462 Swedish women included a dental survey...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-004-5961-5
更新日期:2005-01-01 00:00:00
abstract::Descriptive epidemiological and genealogical data obtained by prospective and retrospective studies on CJD in Slovakia and in patients emigrating from CJD clusters were analysed. Observations contradictory to an exclusively genetic etiology of temporo-spatial accumulation of CJD are presented. Data indicating a geneti...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00143119
更新日期:1991-09-01 00:00:00
abstract::Mendelian randomization uses genetic variants to make causal inferences about a modifiable exposure. Subject to a genetic variant satisfying the instrumental variable assumptions, an association between the variant and outcome implies a causal effect of the exposure on the outcome. Complications arise with a binary ex...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-018-0424-6
更新日期:2018-10-01 00:00:00
abstract::Several studies from many countries have reported a high prevalence (> 9%) of hepatitis C virus (HCV) infection in patients with B-cell non-Hodgkin lymphoma (B-NHL) suggesting a possible etiological role of HCV in the development of B-NHL. Data from the United Kingdom and Turkey, however, did not confirm these observa...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/A:1023380316098
更新日期:2003-01-01 00:00:00
abstract::Coeliac disease is diagnosed by means of jejunal biopsy, an invasive procedure. Anti-gliadin antibodies (AGA) have therefore been used in the first screening of the disease. On the other hand, low titers of AGA are widely detected also in normal subjects. In order to investigate if low levels of AGA could be correlate...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1007301424656
更新日期:1997-01-01 00:00:00
abstract::Immune responses to trivalent inactivated whole virus and monovalent subunit influenza vaccines, used in the season 1986-87, were analyzed in elderly residents in nursing homes. Higher levels of induced antibody were found in the group receiving two doses of trivalent vaccine. This suggests that high risk aged patient...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00156833
更新日期:1989-06-01 00:00:00
abstract::In the PROCAM study hypertriglyceridaemia was much more common among men (18.6%) than women (4.2%). Prevalence increased with age in women, but remained nearly constant at about 20% in men aged 35 years or more. In a multiple regression analysis a strong negative correlation between triglycerides and HDL cholesterol w...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00145359
更新日期:1992-05-01 00:00:00
abstract::An improved semiquantitative self-administered food frequency questionnaire has been designed in order to investigate possible associations between diet and health, to plan nutrition education programmes, and to examine dietary compliance. The questionnaire consists of 16 printed forms and 16 pages with coloured photo...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF01719482
更新日期:1995-04-01 00:00:00
abstract::Chronic health problems may be related to body mass index (BMI, kg/m(2)), but this has been best documented in overweight and obese adults. The primary objective of this study was to identify factors associated with different categories of BMI in elderly men and women from the general population, also including the lo...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-009-9422-z
更新日期:2010-03-01 00:00:00
abstract::This study examines predictors of locating participants that were last contacted 20 years ago using public web-search directories, in order to facilitate longitudinal environmental health research. Participants (n = 3,202) resided in four distinct geographical neighborhoods in Hamilton, Ontario during childhood; they ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-009-9364-5
更新日期:2009-01-01 00:00:00