Abstract:
:Infectious etiologies have been hypothesized for acute leukemias because of their high incidence in early childhood, but have seldom been examined for acute myeloid leukemia (AML). We conducted the first large cohort study to examine perinatal factors including season of birth, a proxy for perinatal infectious exposures, and risk of AML in childhood through young adulthood. A national cohort of 3,569,333 persons without Down syndrome who were born in Sweden in 1973-2008 were followed up for AML incidence through 2010 (maximum age 38 years). There were 315 AML cases in 69.7 million person-years of follow-up. We found a sinusoidal pattern in AML risk by season of birth (P < 0.001), with peak risk among persons born in winter. Relative to persons born in summer (June-August), incidence rate ratios for AML were 1.72 (95 % CI 1.25-2.38; P = 0.001) for winter (December-February), 1.37 (95 % CI 0.99-1.90; P = 0.06) for spring (March-May), and 1.27 (95 % CI 0.90-1.80; P = 0.17) for fall (September-November). Other risk factors for AML included high fetal growth, high gestational age at birth, and low maternal education level. These findings did not vary by sex or age at diagnosis. Sex, birth order, parental age, and parental country of birth were not associated with AML. In this large cohort study, birth in winter was associated with increased risk of AML in childhood through young adulthood, possibly related to immunologic effects of early infectious exposures compared with summer birth. These findings warrant further investigation of the role of seasonally varying perinatal exposures in the etiology of AML.
journal_name
Eur J Epidemioljournal_title
European journal of epidemiologyauthors
Crump C,Sundquist J,Sieh W,Winkleby MA,Sundquist Kdoi
10.1007/s10654-015-0063-0subject
Has Abstractpub_date
2015-12-01 00:00:00pages
1277-85issue
12eissn
0393-2990issn
1573-7284pii
10.1007/s10654-015-0063-0journal_volume
30pub_type
杂志文章abstract::Bacillus cereus is a ubiquitous sporeforming Gram-positive rod that is associated with foodborne outbreaks as well as several opportunistic infections. Inspite of the prevalence of B. cereus associated foodborne outbreaks, subtyping of the species using molecular typing assays was not attempted. In this study we have ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00145422
更新日期:1996-06-01 00:00:00
abstract:PURPOSE:This study investigated whether the association between passive smoking exposure and dysmenorrhea is modified by two susceptibility genes, CYP1A1MspI and CYP1A1HincII. METHODS:This report includes 1,645 (1,124 no dysmenorrhea, 521 dysmenorrhea) non-smoking and non-drinking newly wedding female workers at Anqin...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-008-9250-6
更新日期:2008-01-01 00:00:00
abstract::Whether and how coffee use influences glucose metabolism is still a matter for debate. We investigated whether baseline coffee consumption is longitudinally associated with risk of impaired fasting glucose in a cohort of 18-to-45 year old subjects screened for stage 1 hypertension and whether CYP1A2 polymorphism modul...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-015-9990-z
更新日期:2015-03-01 00:00:00
abstract::External causes of death are important in the pediatric population worldwide. We performed an analysis of all injury-fatalities in children between ages zero and 17 years, between January 2000 and December 2006, in San Diego County, California, United States of America. Information was obtained from the County of San ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-009-9420-1
更新日期:2010-03-01 00:00:00
abstract::Previously published studies on the risk of cancer among male priests have been based on cancer mortality with the exception of one case-control study. The aim of this study was to present estimates of cancer incidence among Nordic male priests. The study cohort for our analyses consisted of 6.5 million men aged 30-64...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-011-9645-7
更新日期:2012-02-01 00:00:00
abstract::We examined factors associated with increased mortality in a cohort of 85,203 adults with a history of imprisonment in New South Wales, Australia, between 1988 and 2002. Information on death was collected through linkage to the Australian National Death Index. The influence of demographic and criminological factors on...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-007-9134-1
更新日期:2007-01-01 00:00:00
abstract::The mechanisms by which Entamoeba histolytica trophozoites adhere to and lyse target cells are reviewed from the perspective of pathogenesis. Adherence via the galactose and N-acetyl-galactosamine inhibitable amebic lectin and possible additional amebic adhesin molecules is followed by target cell death. Inhibition of...
journal_title:European journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1007/BF00239748
更新日期:1987-06-01 00:00:00
abstract::The contribution of different biological pathways to the development of type 2 diabetes was quantified in a case-cohort design based on circulating blood biomarkers from participants aged 35-65 years in the EPIC-Potsdam Study. The analytic sample included 613 participants with incident diabetes and 1965 participants w...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-010-9539-0
更新日期:2011-01-01 00:00:00
abstract::After the introduction of the prostate specific antigen (PSA) test in the 1980s, a sharp increase in the incidence rate of prostate cancer was seen in the United States. The age-specific incidence patterns exhibited remarkable shifts to younger ages, and declining rates were observed at old ages. Similar trends were s...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-016-0185-z
更新日期:2017-06-01 00:00:00
abstract::Paired maternal/cord blood samples were tested for anti-Toxoplasma IgG or IgM antibodies using Biomerieux Micro-EIA2 IgG and IgM test kits. Of the 1503 women tested at the time of delivery, 344 (22.9%) were IgG seropositive. Three hundred and one maternal sera, including 265 that were IgG positive, were tested for IgM...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1007392703037
更新日期:1997-07-01 00:00:00
abstract::Exposed to sewage workers of a wastewater treatment plant and a control group in Thessaloniki, Greece, were examined for antibodies against hepatitis A (anti-HAV) and hepatitis B virus (HBV) infection markers. The main objective of this study was to investigate for epidemiological evidence so as to recommend vaccinati...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/b:ejep.0000020444.64546.3b
更新日期:2004-01-01 00:00:00
abstract::Yersiniosis is caused by Y. enterocolitica and Y. pseudotuberculosis mostly presenting as intestinal infection. The infection is usually acquired from contaminated food. The aim of this study was to determine the seroprevalence of anti-Yersinia antibodies in Austrians. Sera of 750 healthy Austrians from all nine state...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-005-5047-z
更新日期:2006-01-01 00:00:00
abstract::Physical activity is associated to a lower risk of mortality from all-causes and from coronary heart disease. The long-term effects of changes in physical activity on coronary heart disease are, however, less known. We examined the association between changes in leisure time physical activity and the risk of myocardia...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-012-9656-z
更新日期:2012-02-01 00:00:00
abstract::Strategies for controlling the HIV epidemic include education and information campaigns for intravenous drug users (IDUs), as for all high-risk groups, and the provision of various public health measures and treatment. These can only be effective if the IDU is aware of them and has a favourable image of them. A study ...
journal_title:European journal of epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1007/BF01730362
更新日期:1994-04-01 00:00:00
abstract::Multilevel analysis is today considered a more appropriate way to monitor health care performance, as it allows a less biased estimation of uncertainty, and can also separate and quantify contextual (as opposed to individual) effects. Multilevel analysis should be applied as the standard methodology for hospital compa...
journal_title:European journal of epidemiology
pub_type: 评论,信件
doi:10.1007/s10654-005-2065-9
更新日期:2005-01-01 00:00:00
abstract::A prospective study of 53,753 coal miners was undertaken at the Instituto Nacional de Silicosis (INS) in Asturias, Spain, during the period 1971 to 1985. This included a complete medical history, physical examination, pulmonary function tests, and intensive search for pulmonary tuberculosis. A total of 1,136 new cases...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF01719352
更新日期:1994-06-01 00:00:00
abstract::The aims of the NYU Children's Health and Environment Study (CHES) are to evaluate influences of prenatal non-persistent chemical exposures on fetal and postnatal growth and pool our data with the US National Institutes of Health Environmental influences on Child Health Outcomes (ECHO) Program to answer collaborative ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-020-00623-6
更新日期:2020-03-01 00:00:00
abstract::Maternal obesity during pregnancy is an important public health problem in Western countries. Currently, obesity prevalence rates in pregnant women are estimated to be as high as 30%. In addition, approximately 40% of women gain an excessive amount of weight during pregnancy in Western countries. An accumulating body ...
journal_title:European journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1007/s10654-015-0085-7
更新日期:2015-11-01 00:00:00
abstract::No population-based study has assessed the prognostic impact on survival of the CD19 positive lymphocyte count, evaluated by immunophenotyping at diagnosis, in B-cell chronic lymphocytic leukemia (B-CLL). Aiming at addressing this issue, we investigated the clinical outcome of a well-defined population of B-CLL patien...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-005-3777-6
更新日期:2005-01-01 00:00:00
abstract::In this matched-pair study 139 pregnant women were matched on the basis of age to an equal number of non-pregnant women with no signs of genital infection. The mean age was 28.7 years (range 20-41). The cut-offs used for detection of chlamydial antibody were 1:64 and 1:128 for IgG and 1:16 for IgA. IgG antibody at 64 ...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF01717451
更新日期:1994-02-01 00:00:00
abstract::Most studies published to date consider single noise sources and the reported noise metrics are not informative about the peaking characteristics of the source under investigation. Our study focuses on the association between cardiovascular mortality in Switzerland and the three major transportation noise sources-road...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-017-0234-2
更新日期:2017-04-01 00:00:00
abstract::An improved semiquantitative self-administered food frequency questionnaire has been designed in order to investigate possible associations between diet and health, to plan nutrition education programmes, and to examine dietary compliance. The questionnaire consists of 16 printed forms and 16 pages with coloured photo...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF01719482
更新日期:1995-04-01 00:00:00
abstract::Recent evidence suggests potential associations between birthweight and disease in later life. For resource or other reasons recorded birthweight may be unavailable to researchers who have access to uniquely relevant outcome data. The present study examined the validity of parental recall of birthweight. Parents of 10...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1007625030509
更新日期:2000-01-01 00:00:00
abstract::To evaluate the Toxocara spp. eggs environmental contamination of the soil of the urban or suburban area Ancona (Italy), 22 public playgrounds were selected and several cores of soil were taken from any selected areas. To study the Toxocara seroprevalence in the inhabitants of Ancona, blood samples were collected from...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1010853124085
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:To analyse selective factors associated with an unexpectedly low response rate. SUBJECTS AND METHODS:The baseline questionnaire survey of a large prospective follow-up study on the psychosocial health of the Finnish working-aged randomly chosen population resulted in 21,101 responses (40.0%) in 1998. The non...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1020016922473
更新日期:2001-01-01 00:00:00
abstract::Five-hundred-seventy-seven, 6 year old schoolchildren from Rome were examined. 67.8% of them harboured 1 x 10(5) or more Streptococcus mutans CFU per milliliter of saliva. This value was higher than values reported by other Authors. However, the caries prevalence of the subjects in this study was lower than values sho...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1023/a:1007333102815
更新日期:1997-01-01 00:00:00
abstract::In a sample of inhabitants of the Arsi region of Ethiopia prevalence of hepatitis B is around 80% in the age group 20-24. In addition to age, sex and size of family, exposure to tribal practices is a determinant of seropositivity in this group accounting for as much as 20% of the total burden of the infection. Waiting...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/BF00148915
更新日期:1988-09-01 00:00:00
abstract::The objective of this study was to evaluate the association between number of missing teeth and all cause, cardiovascular, and cancer mortality as well as morbidity and to explore whether socio-economic factors mediate this association. An ongoing prospective cohort study of 1462 Swedish women included a dental survey...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-004-5961-5
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:The incidence of Crohn's disease (CD) has been shown to be lower in Southern than in Northern Europe. Data on the frequency of the NOD2/CARD15 mutations for Mediterranean area are very scant. AIM:To determine the incidence of CD from 1979 to 2002 in a township in Sicily together with the allele frequency of...
journal_title:European journal of epidemiology
pub_type: 杂志文章
doi:10.1007/s10654-006-9054-5
更新日期:2006-01-01 00:00:00
abstract::We tested the hypothesis of an association between childhood type 1 diabetes (T1D) risk and nitrate concentration in drinking water in Sardinia, Italy, using Poisson regression analysis. Childhood T1D risk showed an inverse trend with increasing quartile of nitrate level in the total population and among men. A nitrat...
journal_title:European journal of epidemiology
pub_type: 信件
doi:10.1007/s10654-006-0014-x
更新日期:2006-01-01 00:00:00