Abstract：
:The European Prospective Investigation into Cancer and Nutrition (EPIC), which has been established in order to investigate the relations between nutrition and cancer, was initiated in 1990 and involves 10 European countries with heterogeneous dietary patterns and differing cancer incidence rates. This manuscript presents the design, recruitment and baseline characteristics of the Prospect-EPIC cohort co-ordinated in Utrecht, The Netherlands. The cohort is based on volunteers recruited among women participating in a regional breast cancer screening program. It comprises of 17,357 subjects aged 50-69 years at enrolment from Utrecht and vicinity, who have consented to participate in the study and its follow-up. Each participant filled out a general questionnaire and a food frequency questionnaire. Participants were also physically examined and have donated a blood sample. Participation rate was 34.5%. Blood samples were donated by most participants (97.5%) and detailed informed consents were obtained from 87.4% of participants. Mean age at enrolment was 57 years. Anthropometric, lifestyle and morbidity characteristics of the cohort population did not differ largely from those of similar study populations in The Netherlands. Based on the Prospect-EPIC population, we intend to conduct prospective total cohort, nested case-control or case-cohort studies, in order to investigate relations between consumption of certain food groups or nutrients and chronic diseases, including hormone dependant cancers such as breast, colon, endometrial and ovary cancers.
journal_name
Eur J Epidemioljournal_title
European journal of epidemiologyauthors
Boker LK,van Noord PA,van der Schouw YT,Koot NV,Bueno de Mesquita HB,Riboli E,Grobbee DE,Peeters PHdoi
10.1023/a:1020009325797keywords:
subject
Has Abstractpub_date
2001-01-01 00:00:00pages
1047-53issue
11eissn
0393-2990issn
1573-7284journal_volume
17pub_type
杂志文章abstract：:We respond to criticisms of Mendelian randomization (MR) by Mukamal, Stampfer and Rimm (MSR). MSR consider that MR is receiving too much attention and should be renamed. We explain how MR links to Mendel's laws, the origin of the name and our lack of concern regarding nomenclature. We address MSR's substantive points ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-020-00622-7
更新日期：2020-02-01 00:00:00
abstract：:The aim of the study was to evaluate the relationship between marital status and blood pressure, and to assess the risk of hypertension in adult Polish men, after adjustment for BMI. Material comprised the data of 2,271 healthy men, aged 25-60, occupationally active inhabitants of Wroclaw (south-western Poland). Arter...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-005-1752-x
更新日期：2005-01-01 00:00:00
abstract：:Patients with cardiovascular disease (CVD) are a heterogeneous group regarding their body mass index (BMI) levels at the time of diagnosis. To address the heterogeneity of CVD, we examined the trajectories of change in body mass index (BMI) and in other cardio-metabolic risk factors before CVD diagnosis. The study inc...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-016-0131-0
更新日期：2016-06-01 00:00:00
abstract：:Respiratory health effects of short-term exposure to ambient air pollution have been examined in 120 'asthma-like' school-aged children in some areas of Emilia-Romagna (urban-industrial and rural area). They kept a daily diary, through 12 weeks, for respiratory symptoms, PEF measurements, drug consumption and daily ac...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/b:ejep.0000032373.28250.84
更新日期：2004-01-01 00:00:00
abstract：:We describe a Dot-ELISA system for the rapid, specific and reliable assessment of a subject's antitetanus immune status. The conditions for Dot-ELISA were selected to give positive reactions only for sera with antitetanus antibody titers equal to or higher than 0.06 I.U./ml, considered to represent protection when usi...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00145053
更新日期：1989-03-01 00:00:00
abstract：:GB virus C subtype (GBV-C) seems to share the same routes of transmission as other parenteral transmitted viruses. We have evaluated the prevalence of GBV-C in 247 patients with potential risk for GBV-C infection and in 91 healthy blood donors. The presence of GBV-C RNA was examined by polymerase chain reaction in ser...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007448501661
更新日期：1998-09-01 00:00:00
abstract：:A seroprevalence survey of antibodies to HCV was carried out among 2788 hemodialysis (HD) patients in a region of central Italy. Anti-HCV seroprevalence was 28.6%. A multivariate analysis of risk factors showed a significant association with time on HD, history of blood transfusion and metropolitan area of residence. ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007592912010
更新日期：1999-01-01 00:00:00
abstract：:Multilevel analysis is today considered a more appropriate way to monitor health care performance, as it allows a less biased estimation of uncertainty, and can also separate and quantify contextual (as opposed to individual) effects. Multilevel analysis should be applied as the standard methodology for hospital compa...
journal_title：European journal of epidemiology
pub_type： 评论,信件
doi：10.1007/s10654-005-2065-9
更新日期：2005-01-01 00:00:00
abstract：:This study was conducted to determine the epidemiological profile of urolithiasis in Kuwaiti patients and the associated metabolic abnormalities favouring stone formation in this patient population. Between 1986 and 1994, a total of 421 Kuwaiti patients were studied in Al-Amiri renal stone laboratory. The mineral comp...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007346727944
更新日期：1997-02-01 00:00:00
abstract：:Edema and hand strength measurements are useful for the recovery assessment of patients with a hand lesion. This work determined and compared estimates of hand volume, grip strengths (measured with a Jamar and a Collins dynamometer), and pinch strength (with a Jamar pinch gauge) in terms of sex and age with or without...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007308719731
更新日期：1997-04-01 00:00:00
abstract：:The use of primary care electronic health records for research is abundant. The benefits gained from utilising such records lies in their size, longitudinal data collection and data quality. However, the use of such data to undertake high quality epidemiological studies, can lead to significant challenges particularly...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-020-00677-6
更新日期：2020-08-27 00:00:00
abstract：:Two papers were extracted and pooled data from published sources were used to estimate the distribution of BMI values for adults living in many countries around the world. The NCD Risk Factor Collaboration and the Global Burden of Disease Study 2013 presented data for 200 and 188 countries, respectively. We extracted ...
journal_title：European journal of epidemiology
pub_type： 信件
doi：10.1007/s10654-019-00503-8
更新日期：2019-07-01 00:00:00
abstract：:Recent epidemiological studies have suggested passive smoking as possible risk factors in breast cancer etiology. However, the evidence is not conclusive. We conducted a meta-analysis of the risk of breast cancer associated with passive smoking. Eleven studies were identified through Medline, Cancer Abstracts and abst...
journal_title：European journal of epidemiology
pub_type： 杂志文章,meta分析
doi：10.1023/a:1010967513957
更新日期：2000-01-01 00:00:00
abstract：:In this paper we have analyzed several risk factors for developing nosocomial infections at a Surgical Service of the Hospital Clinico Universitario "San Cecilio", based on a retrospective follow-up program designed specifically for this study. Of all patients admitted to the Service from January 1 to June 17, 1987, w...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00144759
更新日期：1988-06-01 00:00:00
abstract：:During the last decade there have been significant socio-demographic changes in Spain with potential impact on gestational length. The aim of the study was to describe the evolution of gestational age during 1997-2008, separately for native-born and immigrant population, in order to assess their contribution to the ov...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-011-9591-4
更新日期：2011-07-01 00:00:00
abstract：:The aim of this study was to determine the relationship between alcohol consumption and occurrence of peripheral arterial disease in the general population. During 1988 in a cross sectional survey, the Edinburgh Artery Study, 1,592 men and women aged 55-74 years were selected at random from the age-sex registers of te...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF01719940
更新日期：1995-02-01 00:00:00
abstract：:In this matched-pair study 139 pregnant women were matched on the basis of age to an equal number of non-pregnant women with no signs of genital infection. The mean age was 28.7 years (range 20-41). The cut-offs used for detection of chlamydial antibody were 1:64 and 1:128 for IgG and 1:16 for IgA. IgG antibody at 64 ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF01717451
更新日期：1994-02-01 00:00:00
abstract：:At present, we can observe an evolution in ideas about the detection of HIV seropositivity through a qualitative analysis of specialised literature on the ethical aspects of AIDS. In the case of this disease, systematic screening of the population does not correspond to epidemiological criteria: it is wasteful, troubl...
journal_title：European journal of epidemiology
pub_type： 杂志文章,评审
doi：10.1007/BF00237357
更新日期：1991-03-01 00:00:00
abstract：:The Di.S.Co. Project--Sezze District Community Control--is aimed at achieving in the general population the prevention of chronic diseases through community intervention. Two areas are enrolled, one for intervention (25,706 subjects) and one for reference (12,655 subjects). In 1983 the first survey was conducted on a ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00145002
更新日期：1991-07-01 00:00:00
abstract：:The objective of this study was to determine the tetanus immunity status of pregnant women at the time of delivery according to tetanus toxoid (TT) vaccination coverage during their most pregnancy. The serum anti-tetanus antibody levels of 493 mothers who had live births at a hospital in Ankara were determined by enzy...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1015507402480
更新日期：2001-01-01 00:00:00
abstract：:Four hundred and twenty seven idiopathic peripheral facial palsy (IPFP) patients admitted to the Otolaryngology Department of the Soroka Medical Center in southern Israel between 1978 and 1982 were characterized and analyzed by age, sex and season of illness. An average annual incidence rate of 33.6 patients per 100,0...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00211536
更新日期：1986-09-01 00:00:00
abstract：:Cytomegalovirus (CMV) infection was one of the most common opportunistic infections in AIDS patients, leading to blindness or life-threatening disease in about 40% of patients in the later stages of AIDS before highly active antiretroviral therapy (HAART). In a retrospective multicenter study we investigated the incid...
journal_title：European journal of epidemiology
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1023/a:1007619323939
更新日期：2000-05-01 00:00:00
abstract：BACKGROUND:Consumption of high doses of alcohol on a single occasion (binge drinking) may harm the developing foetus and pregnant women are advised to avoid binge drinking while pregnant. We present characteristics of Danish women who binge drank in the pre-and post recognised part of their pregnancy. METHODS:During t...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-008-9265-z
更新日期：2008-01-01 00:00:00
abstract：:Physical activity is associated to a lower risk of mortality from all-causes and from coronary heart disease. The long-term effects of changes in physical activity on coronary heart disease are, however, less known. We examined the association between changes in leisure time physical activity and the risk of myocardia...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-012-9656-z
更新日期：2012-02-01 00:00:00
abstract：:The adhesion of Vibrio cholerae O1 strains to human intestinal epithelial cell, Intestine 407, was analyzed by flow cytometer. According to positive percentages of Intestine 407 cells adhered by V. cholerae, two groups of V. cholerae strains were classified as follows: more adhesive (more than 50%), less adhesive (les...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007352713686
更新日期：1997-09-01 00:00:00
abstract：:Recent studies have confirmed important regional differences in the prevalence of obesity, as well as a tendency for this prevalence to increase. Determination of the social factors involved in obesity may be very useful to design intervention and prevention strategies. This transverse study was undertaken in Pizarra ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/b:ejep.0000013254.93980.97
更新日期：2004-01-01 00:00:00
abstract：:Exogenous sex hormones seem to play a role in colorectal carcinogenesis. Little is known about the influence of different types or durations of postmenopausal hormone therapy (HT) on colorectal cancer risk. A nationwide cohort of women 50-79 years old without previous cancer (n = 1,006,219) were followed 1995-2009. In...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-016-0116-z
更新日期：2016-05-01 00:00:00
abstract：:In order to study the etiology of endemic goiter in the north-western part of Tunisia, we examined 93 adolescents of this region. We measured urinary iodine concentrations, serum total thyroxine, total triiodothyronine, thyrotropin, thyroglobulin and antithyrogobulin antibody concentrations. The adolescents were quest...
journal_title：European journal of epidemiology
pub_type： 信件
doi：10.1023/a:1007325100138
更新日期：1997-04-01 00:00:00
abstract：:In an effort to find an indicator for use in studies of the epidemiological impact of drug abuse in California in the late 1960s, we recognized that, for comparative analyses, cause specific mortality was less attractive than total mortality of the population group principally affected, young adults. This paper examin...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00419492
更新日期：1986-12-01 00:00:00
abstract：:A group of 709 randomly selected males aged 18-55 years living in the city of Amsterdam, the Netherlands, were questioned about sexual lifestyle and related behavior. A substantial proportion (10%) of these men appeared to be homo- or bisexual. Of these homo- and bisexual men, 16.5% were predicted to be HIV seropositi...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00157403
更新日期：1993-07-01 00:00:00
