Abstract：
:Cytomegalovirus (CMV) infection was one of the most common opportunistic infections in AIDS patients, leading to blindness or life-threatening disease in about 40% of patients in the later stages of AIDS before highly active antiretroviral therapy (HAART). In a retrospective multicenter study we investigated the incidence of CMV retinitis and organ involvement in Northern Italy before (1995 and 1996) and after the introduction of HAART (1997 and 1998) as well as the data regarding CMV antigenemia. We found a sharp drop in the incidence of CMV disease in AIDS patients as well as a decline in the incidence of relapses of CMV-disease after the widespread introduction of HAART. Moreover, there was a decrease in the incidence of antigenemia-positive cases in AIDS patients in the era of HAART and the median CMV viral load was significantly higher in patients who didn't receive HAART than in patients who received HAART (p = 0.001, t test).
journal_name
Eur J Epidemioljournal_title
European journal of epidemiologyauthors
Varani S,Spezzacatena P,Manfredi R,Chiodo F,Mastroianni A,Ballarini P,Boschini A,Lazzarotto T,Landini MPdoi
10.1023/a:1007619323939keywords:
subject
Has Abstractpub_date
2000-05-01 00:00:00pages
433-7issue
5eissn
0393-2990issn
1573-7284journal_volume
16pub_type
临床试验,杂志文章,多中心研究abstract：:The non-vitamin K antagonist oral anticoagulants (NOACs) have been increasingly prescribed in clinical practice for stroke prevention in patients with nonvalvular atrial fibrillation (AF). Direct comparisons between NOACs in trials are lacking, leaving an important clinical decision-making gap. We aimed to perform a s...
journal_title：European journal of epidemiology
pub_type： 杂志文章,meta分析
doi：10.1007/s10654-018-0415-7
更新日期：2019-02-01 00:00:00
abstract：:In the present study data on the incidence of HBV and HCV were used to indicate the prevalence of and trends in risk behavior, assuming that drug users (DUs) who become infected with HBV or HCV are also at risk for infection with HIV. In addition, we determined to that extent the transmission patterns of HIV, HBV and ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00146260
更新日期：1993-05-01 00:00:00
abstract：:The aim of this analysis is to compare screening strategies with haemoglobin A(1c) (HbA(1c)), fasting plasma glucose (FPG) or combined measures in the identification of individuals at high risk for diabetes. Applying American Diabetes Association thresholds for FPG and HbA(1c) screening, 6,803 subjects free of diabete...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-011-9619-9
更新日期：2011-10-01 00:00:00
abstract：:The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric, dermatological, oncological, and respiratory diseases. As of 2008, 14,926 subjects aged 45 years or over compris...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-013-9866-z
更新日期：2013-11-01 00:00:00
abstract：:The debate around vaccines has been in the spotlight over the last few years in Europe, both within the scientific community and the general public debate. In this regard, the case of the Italian vaccination debate is particularly worrying given that Italy has been one of the European countries with the highest number...
journal_title：European journal of epidemiology
pub_type： 信件
doi：10.1007/s10654-020-00670-z
更新日期：2020-08-01 00:00:00
abstract：:The aim of this study was to examine the validity--estimated as the sensitivity, specificity, and predictive values--of questionnaire-based parental reporting on Danish children's use of asthma drugs. Within a population-based cross-sectional study on the association between asthma and dental anxiety, we compared pare...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-004-1501-6
更新日期：2005-01-01 00:00:00
abstract：:Bone Paget's disease is heterogeneously distributed and several foci of high prevalence have been reported in Spain. The aim of the present work was to determine the prevalence of the disease in a zone situated in the northwestern sector of the Province of Salamanca (Spain) using a cross sectional epi-demiological stu...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007449206061
更新日期：1997-10-01 00:00:00
abstract：:The authors studied a population of 5634 students from various continents to determine possible correlations between risk factors and seroprevalence of HIV infection. In the African sample the seroprevalence rate was 3.5%; the age range from 19 to 30 years was most affected; prevalence differences between the sexes we...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007635104096
更新日期：2000-02-01 00:00:00
abstract：:To evaluate the relationship between duration of preoperative stay and the risk of nosocomial infection, we studied 449 patients who underwent surgery at the University Hospital of Granada during the first six months of 1986. Patients were chosen from two cross-sectional surveys. Nosocomial infection was studied throu...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00218680
更新日期：1991-11-01 00:00:00
abstract：:Sixteen hundred and thirty seven isolates of Neisseria gonorrhoeae isolated over a two year period were serotyped using three panels of monoclonal antibodies. The isolates comprised 687 serogroup WI strains and 950 serogroup WII/III strains. The antibodies used in the panels were those developed by Pharmacia (Ph) and ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00144994
更新日期：1991-07-01 00:00:00
abstract：:Evidence that childbearing is associated with future development of diabetes remains conflicting and the role of pregnancy loss in this association has not been investigated. We aimed to examine whether pregnancy and/or pregnancy loss (miscarriage, abortion, or stillbirth) are associated with maternal higher risk of d...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-012-9683-9
更新日期：2012-05-01 00:00:00
abstract：:The Dementias Platform UK Data Portal is a data repository facilitating access to data for 3 370 929 individuals in 42 cohorts. The Data Portal is an end-to-end data management solution providing a secure, fully auditable, remote access environment for the analysis of cohort data. All projects utilising the data are b...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-020-00633-4
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:In epidemiological studies on asthma determinants an extreme variability in results exists, probably due to different criteria utilised for defining of an asthma 'case' and for measuring determinants. We aimed to assess multiple indicators and multiple determinants of asthma in young adults by applying laten...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-006-9062-5
更新日期：2006-01-01 00:00:00
abstract：:Coxiella burnetii, the etiological agent of Q-fever has recently been isolated from sheep in southern Sweden. In this region 24-30% of sheep farmers have been exposed to the organism as shown by serological measurements. In veterinarians, another group with high risk of exposure to C. burnetii, about 12% have antibodi...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00158795
更新日期：1993-03-01 00:00:00
abstract：:In an effort to find an indicator for use in studies of the epidemiological impact of drug abuse in California in the late 1960s, we recognized that, for comparative analyses, cause specific mortality was less attractive than total mortality of the population group principally affected, young adults. This paper examin...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00419492
更新日期：1986-12-01 00:00:00
abstract：:It has been suggested that Helicobacter pylori colonization may protect against diarrhoeagenic gastrointestinal infections. The aim of this analysis was to investigate the association between H. pylori infection and the frequency of diarrhoeal episodes among adults. Helicobacter pylori infection status was determined ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1015618112695
更新日期：2001-01-01 00:00:00
abstract：:The immune status against polioviruses was investigated in a population of 545 students aged 11-20 years residing in the Neapolitan area, who had completed the vaccination cycle with four doses of OPV 5 to over 15 years before. Assuming as unprotected those individuals without detectable neutralizing antibodies at the...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00144420
更新日期：1996-02-01 00:00:00
abstract：:Increased fibroblast growth factor 23 (FGF23) concentrations have emerged as a novel risk factor for heart failure and stroke but not for myocardial infarction (MI). Yet, most studies on MI were conducted in coronary artery disease (CAD) patients and the elderly. Evidence is unclear in subjects without CAD and for str...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-014-9982-4
更新日期：2015-02-01 00:00:00
abstract：:The aim of the study was to evaluate the relationship between marital status and blood pressure, and to assess the risk of hypertension in adult Polish men, after adjustment for BMI. Material comprised the data of 2,271 healthy men, aged 25-60, occupationally active inhabitants of Wroclaw (south-western Poland). Arter...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-005-1752-x
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:This study investigated whether the association between passive smoking exposure and dysmenorrhea is modified by two susceptibility genes, CYP1A1MspI and CYP1A1HincII. METHODS:This report includes 1,645 (1,124 no dysmenorrhea, 521 dysmenorrhea) non-smoking and non-drinking newly wedding female workers at Anqin...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-008-9250-6
更新日期：2008-01-01 00:00:00
abstract：:The aim of the study was to assess the performance of weight related nutritional markers [reported involuntary weight loss (WL) greater than 10%, measured WL and body mass index (BMI)] in predicting survival at AIDS stage. The three anthropometric indices were used as time dependent variables in Cox models to predict ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007696530440
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE:To analyse the relationships between major cardiovascular risk factors in French men and their spouses' occupational category (OC), taking their own OC into account. DESIGN:A large sample of volunteers working in the French National Electricity and Gas Company (GAZEL). As a check of the robustness, the same ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1012709700189
更新日期：2001-01-01 00:00:00
abstract：:The relationship of socioeconomic indicators (education, occupation and residence) to short-term all cause mortality and coronary heart disease (CHD) mortality was evaluated in an Italian population sample. Socioeconomic indicators (education, occupational level and residence) and major CHD risk factors were measured ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007640424387
更新日期：2000-06-01 00:00:00
abstract：:The contribution of different biological pathways to the development of type 2 diabetes was quantified in a case-cohort design based on circulating blood biomarkers from participants aged 35-65 years in the EPIC-Potsdam Study. The analytic sample included 613 participants with incident diabetes and 1965 participants w...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-010-9539-0
更新日期：2011-01-01 00:00:00
abstract：:The aetiology of childhood cancers remains largely unknown. Space-time clustering of cases might imply an aetiological role of infections. We aimed to review the evidence of space-time clustering of specific childhood cancers. We searched Medline and Embase for population-based studies that covered a pre-defined study...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-018-0456-y
更新日期：2019-01-01 00:00:00
abstract：:Prenatal famine exposure has previously been shown to be associated with cardiovascular disease and type II diabetes in adulthood. In the current study, we could not demonstrate an effect of prenatal exposure to famine in 2254 term singletons born during the 1944-1945 Dutch famine on adult mortality up to the age of 5...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-005-7921-0
更新日期：2005-01-01 00:00:00
abstract：:To estimate the prevalence of infection by hepatitis C virus (HCV) in general practice, and to investigate attitudes to screening for HCV, a specific questionnaire was sent to the sentinel general practitioners (SGPs) of the French Sentinel Network. From the figures reported by SGPs, the number of anti-HCV tests perfo...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007535722726
更新日期：1999-02-01 00:00:00
abstract：:Adherence of Candida albicans to host tissues is considered a crucial step in the pathogenesis of candidiasis. Using in vitro assays, it was demonstrated that the yeast-mycelium transition was an important phenomenon in the acquisition of adhesive properties. Proteins with MWs of 60, 68, 200 and greater than 200 kDa s...
journal_title：European journal of epidemiology
pub_type： 杂志文章,评审
doi：10.1007/BF00221338
更新日期：1991-01-01 00:00:00
abstract：:At present, we can observe an evolution in ideas about the detection of HIV seropositivity through a qualitative analysis of specialised literature on the ethical aspects of AIDS. In the case of this disease, systematic screening of the population does not correspond to epidemiological criteria: it is wasteful, troubl...
journal_title：European journal of epidemiology
pub_type： 杂志文章,评审
doi：10.1007/BF00237357
更新日期：1991-03-01 00:00:00
abstract：:Sleep-disordered breathing (SDB) and lower socio-professional status have in common a series of risk factors for ill health such as sedentary lifestyle, weight excess, heavy alcohol and tobacco consumption. We hypothesised that SDB will be more prevalent in lower socio-professional groups. A total of 496 male middle a...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1010910821431
更新日期：2001-01-01 00:00:00
