Abstract：
:The objective was to determine the prevalence of hepatitis B virus (HBV) infection in long-stay institutionalized mentally handicapped adults and to develop a vaccination programme for them. The study was carried out in 1994. The subjects were 171 mentally handicapped adults aged 37-76 (median age 56) with a median hospital stay of 30 years (range 6-47). Markers for infection were determined using ELISA. Seronegative patients were vaccinated using the standard schedule, and the titre of antiHBs reached was determined later. The prevalence of seropositive subjects was 81.3%. Seropositive subjects had a longer hospital stay (median stay of 32 years, range: 15-47) than seronegative ones (median stay of 15 years, range: 6-33). A total of 43.3% of the vaccinated subjects developed antiHBs antibodies (GMT: 135 IU/l). The high prevalence of HBV exposure is probably a legacy of a past era which is reflected in patients with prolonged institutionalisation in a closed regime. The need for immediate vaccination of mentally handicapped subjects is of the utmost importance, as it has been shown that the response to the vaccine worsens with age.
journal_name
Eur J Epidemioljournal_title
European journal of epidemiologyauthors
Asensio F,Bayas JM,Bertran MJ,Asenjo MAdoi
10.1023/a:1026793900057keywords:
subject
Has Abstractpub_date
2000-01-01 00:00:00pages
725-9issue
8eissn
0393-2990issn
1573-7284journal_volume
16pub_type
杂志文章abstract：:The authors studied a population of 5634 students from various continents to determine possible correlations between risk factors and seroprevalence of HIV infection. In the African sample the seroprevalence rate was 3.5%; the age range from 19 to 30 years was most affected; prevalence differences between the sexes we...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007635104096
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abstract：:The aim of this study was to evaluate completeness of tuberculosis notification in Bichat Claude-Bernard University Hospital and to evaluate whether misclassification of atypical mycobacterial infection could have contributed to the inaccuracy of tuberculosis notification. Data from Microbiology Laboratory of the hosp...
journal_title：European journal of epidemiology
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abstract：:The article was originally published electronically on the publisher's internet portal (currently SpringerLink) on 24 January 2018 without open access. ...
journal_title：European journal of epidemiology
pub_type： 杂志文章,已发布勘误
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abstract：BACKGROUND:Flagellin subunit A gene (flaA) typing of Campylobacter has been recognized by several groups as a relatively simple and quick genotyping method. The present study aimed to create, for the first time in Greece, a database with flaA restriction patterns, which could be used for future epidemiological and clin...
journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
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doi：10.1023/a:1015622016579
更新日期：2001-01-01 00:00:00
abstract：UNLABELLED:High level of total serum calcium within the normal range has been associated with increased cardiovascular risk. We wanted to evaluate whether the physiological active ionised form of calcium also was a risk factor for cardiovascular disease (CVD). METHODS:A total of 974 participants from a health survey i...
journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
pub_type： 杂志文章
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
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doi：10.1007/s10654-013-9873-0
更新日期：2014-08-01 00:00:00
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journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF01719432
更新日期：1995-06-01 00:00:00
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journal_title：European journal of epidemiology
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doi：10.1007/BF00141800
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
pub_type： 杂志文章,多中心研究
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journal_title：European journal of epidemiology
pub_type： 杂志文章,评审
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journal_title：European journal of epidemiology
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更新日期：2012-05-01 00:00:00
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journal_title：European journal of epidemiology
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更新日期：2006-01-01 00:00:00
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journal_title：European journal of epidemiology
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journal_title：European journal of epidemiology
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更新日期：2011-09-01 00:00:00
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journal_title：European journal of epidemiology
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abstract：:Suicide mortality was examined between 1970 and 1998 in a cohort of 19,801 persons categorized as indigenous Sami in Arctic Norway. Standardized mortality ratios (SMR) were calculated using the suicide rates of the rural population of Arctic Norway as reference. There was a significant moderate increased risk for suic...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-006-9052-7
更新日期：2006-01-01 00:00:00
