Abstract：
:The Generation R Study is a population-based prospective cohort study from fetal life until young adulthood. The study is designed to identify early environmental and genetic causes of normal and abnormal growth, development and health from fetal life until young adulthood. The study focuses on four primary areas of research: (1) growth and physical development; (2) behavioral and cognitive development; (3) diseases in childhood; and (4) health and healthcare for pregnant women and children. In total, 9778 mothers with a delivery date from April 2002 until January 2006 were enrolled in the study. Of all eligible children at birth, 61% participate in the study. Data collection in the prenatal phase included physical examinations, questionnaires, fetal ultrasound examinations and biological samples. In addition, more detailed assessments are conducted in a subgroup of 1232 pregnant women and their children. The children form a prenatally recruited birth-cohort that will be followed until young adulthood. Eventually, results forthcoming from the Generation R Study have to contribute to the development of strategies for optimizing health and healthcare for pregnant women and children.
journal_name
Eur J Epidemioljournal_title
European journal of epidemiologyauthors
Jaddoe VW,Mackenbach JP,Moll HA,Steegers EA,Tiemeier H,Verhulst FC,Witteman JC,Hofman Adoi
10.1007/s10654-006-9022-0subject
Has Abstractpub_date
2006-01-01 00:00:00pages
475-84issue
6eissn
0393-2990issn
1573-7284journal_volume
21pub_type
杂志文章abstract：:A rare case report of American leishmaniasis imported to Italy after a prolonged journey in Brazil is described, and discussed according to the recent epidemiologic, diagnostic, and clinical literature evidence. Since a delayed diagnosis and treatment of American leishmaniasis outside endemic areas is common (due to a...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1015622016579
更新日期：2001-01-01 00:00:00
abstract：:The prevalence of serologic evidence of hepatitis B virus infection in various populations in Greece was examined to provide data for formulating cost-effective strategies for prevaccination screening. Markers were detected in 17.5% of 320 healthy persons, 73.3% of 273 multiply transfused patients and 61.0% of 146 hae...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00141800
更新日期：1985-06-01 00:00:00
abstract：:Cystinuria is an autosomal recessive disorder of the kidneys and small intestine, affecting a luminal transport mechanism shared by cystine, ornithine, arginine and lysine. When cystine exceeds its solubility at low pH, the risk of stone formation increases. The data reported in the literature show a variation for the...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007522215041
更新日期：1999-08-01 00:00:00
abstract：:In this paper we have analyzed several risk factors for developing nosocomial infections at a Surgical Service of the Hospital Clinico Universitario "San Cecilio", based on a retrospective follow-up program designed specifically for this study. Of all patients admitted to the Service from January 1 to June 17, 1987, w...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00144759
更新日期：1988-06-01 00:00:00
abstract：:The relationship of socioeconomic indicators (education, occupation and residence) to short-term all cause mortality and coronary heart disease (CHD) mortality was evaluated in an Italian population sample. Socioeconomic indicators (education, occupational level and residence) and major CHD risk factors were measured ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007640424387
更新日期：2000-06-01 00:00:00
abstract：:To estimate the prevalence of infection by hepatitis C virus (HCV) in general practice, and to investigate attitudes to screening for HCV, a specific questionnaire was sent to the sentinel general practitioners (SGPs) of the French Sentinel Network. From the figures reported by SGPs, the number of anti-HCV tests perfo...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1007535722726
更新日期：1999-02-01 00:00:00
abstract：:Over a period of seven years (from 1980 to 1987) 58 acute viral hepatitis A cases were admitted to the Departments for Infectious Diseases. This number represents 10.76% of all viral hepatitis patients. Most of the patients had travelled to foreign countries or to areas in Italy with high hepatitis A virus (HAV) circu...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00155562
更新日期：1990-03-01 00:00:00
abstract：:C-reactive protein (CRP) was proposed as a stronger predictor of cardiovascular events than low-density lipoprotein cholesterol (LDL-C); however, these associations may differ between myocardial infarction (MI) and stroke. We compared statistically the associations of CRP and LDL-C levels with risk of MI versus stroke...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-007-9141-2
更新日期：2007-01-01 00:00:00
abstract：:Sample surveys are used to investigate occurrence and determinants of diseases in populations. Their reliability is influenced by quality of sampling frame and response rate. We investigated relationship between sampling frame type and response rates and assessed their impact on non-response bias, using data from the ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-005-0600-3
更新日期：2005-01-01 00:00:00
abstract：:1167 workers of Lorraine (France) iron mines, a random sample of 5600 workers aged 35 to 55 years, at work in 1975 constituted the initial cohort that was examined twice at 5-year intervals after the first examination. A questionnaire on respiratory symptoms and smoking habits (MRC questionnaire) plus questions on the...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00146382
更新日期：1992-07-01 00:00:00
abstract：:In order to investigate the shift in the rates and levels of antibody to hepatitis A virus, 567 children in 20 isolated groups of five day-care centers were observed over a period of 8 months during which the seasonal rise in hepatitis A morbidity occurs. Increases in the proportion of seropositive ranging from 5 to 3...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00145647
更新日期：1987-12-01 00:00:00
abstract：:In order to assess the seroprevalence of Borrelia burgdorferi in Romania and to define associated risk factors, a cross-sectional, observational study was performed in 13 districts during 1999. Sera from healthy blood donors (1,598) and from forestry workers (1,048) were tested. A two-step testing strategy was used in...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1015600729900
更新日期：2001-01-01 00:00:00
abstract：:Language is an important determinant of health, but analyses of linguistic inequalities in mortality are scant, especially for Canadian linguistic groups with European roots. We evaluated the life expectancy gap between the Francophone majority and Anglophone minority of Québec, Canada, both over time and across major...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-011-9644-8
更新日期：2012-01-01 00:00:00
abstract：:There have been recent reports of substantial increases occurring in the incidence of and/or mortality from tongue and mouth cancers in several countries. In this paper using data from Scotland (1960-89) we report on time trends in pharyngeal cancer. Similar increases in rates are evident for cancers of the oropharynx...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00211431
更新日期：1993-11-01 00:00:00
abstract：:This study examines predictors of locating participants that were last contacted 20 years ago using public web-search directories, in order to facilitate longitudinal environmental health research. Participants (n = 3,202) resided in four distinct geographical neighborhoods in Hamilton, Ontario during childhood; they ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-009-9364-5
更新日期：2009-01-01 00:00:00
abstract：:Determine age-specific infection fatality rates for COVID-19 to inform public health policies and communications that help protect vulnerable age groups. Studies of COVID-19 prevalence were collected by conducting an online search of published articles, preprints, and government reports that were publicly disseminated...
journal_title：European journal of epidemiology
pub_type： 杂志文章,meta分析
doi：10.1007/s10654-020-00698-1
更新日期：2020-12-01 00:00:00
abstract：:To assess whether two inflammatory markers, C-reactive protein (CRP) and interleukin-6 (IL-6), and change in their concentrations over 12 years, are associated with lung function (FVC and FEV(1)) 12 years after baseline. Data are from over 1,500 participants free from self-reported respiratory problems in a large-scal...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-010-9526-5
更新日期：2011-02-01 00:00:00
abstract：:To study the association between postmenopausal hormone therapy (PMH) use and the risk of rheumatoid arthritis (RA) stratifying the cases by the presence/absence of antibodies against citrullinated peptides (ACPA). A subset of the Epidemiological Investigation of RA (EIRA), a population-based case-control study, compr...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-015-0004-y
更新日期：2015-05-01 00:00:00
abstract：:In a prevalence study, we evaluated whether recurrent physician-attended URTI episodes are more common in asthmatic children as compared to age- and gender-matched controls. URTI proneness, defined as > or = 5 episodes of rhinitis/pharyngitis, sinusitis, laryngitis/tracheitis or otitis media in a 24-month period, was ...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1025674816487
更新日期：2003-01-01 00:00:00
abstract：:At the crossroads between sciences, epidemiology brings together the social and the biological to examine social inequalities in health. The concept of biological capital represents the accumulated history of biological experiences, alongside the other forms of accumulated capital, notably cultural, economic and socia...
journal_title：European journal of epidemiology
pub_type： 信件
doi：10.1007/s10654-019-00539-w
更新日期：2019-10-01 00:00:00
abstract：:Vaccinations and infections are possible triggers of Guillain-Barré syndrome (GBS). However, studies on GBS after vaccinations during the influenza A(H1N1)pmd09 pandemic in 2009, show inconsistent results. Only few studies have addressed the role of influenza infection. We used information from national health data-ba...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-015-0047-0
更新日期：2016-01-01 00:00:00
abstract：:Biomarkers are considered as tools to enhance cardiovascular risk estimation. However, the value of biomarkers on risk estimation beyond European risk scores, their comparative impact among different European regions and their role towards personalised medicine remains uncertain. Biomarker for Cardiovascular Risk Asse...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-014-9952-x
更新日期：2014-10-01 00:00:00
abstract：:This case-control study comprised 100 histologically verified laryngeal cancer patients and 100 hospital controls matched with cases by sex, age and place of residence. The following variables were tested for their association with cancer of the larynx: marital status, educational level, hard liquor consumption, cigar...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF01721228
更新日期：1995-08-01 00:00:00
abstract：:This paper describes a cohort of people living in Victoria, Australia, diagnosed with incident HIV infection and identified through routine HIV surveillance. All HIV diagnoses notified to the Victorian HIV Registry between January 1997 and September 1998 were included. Infections were classified as incident if there w...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1017974319692
更新日期：2001-01-01 00:00:00
abstract：:Recent epidemiological studies have suggested passive smoking as possible risk factors in breast cancer etiology. However, the evidence is not conclusive. We conducted a meta-analysis of the risk of breast cancer associated with passive smoking. Eleven studies were identified through Medline, Cancer Abstracts and abst...
journal_title：European journal of epidemiology
pub_type： 杂志文章,meta分析
doi：10.1023/a:1010967513957
更新日期：2000-01-01 00:00:00
abstract：:Environmental and atmospheric factors have been associated with meningitis epidemics in sub-Saharan Africa but not in the northern hemisphere. An epidemic of meningitis caused by different agents occurred in a health district in northern Italy during the first quarter of 2003: there were 50 cases compared to the expec...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-006-9013-1
更新日期：2006-01-01 00:00:00
abstract：:To evaluate the role of nutritional factors in the etiology of endometrial cancer, we performed a case-cohort analysis using data from women enrolled in the National Breast Screening Study in Canada from 1980 to 1985. For this analysis, a subcohort was constructed by selecting a 10% random sample from the 56,837 women...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1023/a:1011012621990
更新日期：2000-01-01 00:00:00
abstract：:The objective of this study was to evaluate the association between number of missing teeth and all cause, cardiovascular, and cancer mortality as well as morbidity and to explore whether socio-economic factors mediate this association. An ongoing prospective cohort study of 1462 Swedish women included a dental survey...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-004-5961-5
更新日期：2005-01-01 00:00:00
abstract：:This paper describes 188 cases of early breast cancer in which age, menopause status, smoking, and pathological characteristics of the tumor were investigated, as well as status and levels of estrogen and progesterone hormone receptors. Estrogen and progesterone receptor status did not seem to differ between smokers a...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/BF00145005
更新日期：1991-07-01 00:00:00
abstract：OBJECTIVE:To identify predictors of chronic obstructive pulmonary disease (COPD) severity and assess the relation between COPD severity and risk of cardiovascular outcomes. STUDY DESIGN AND SETTING:A cohort of patients with diagnosed and treated COPD was compiled from the Saskatchewan Health longitudinal databases. We...
journal_title：European journal of epidemiology
pub_type： 杂志文章
doi：10.1007/s10654-006-9066-1
更新日期：2006-01-01 00:00:00
