Atmospheric pressure chemical ionization mass spectrometry of pyridine and isoprene: potential breath exposure and disease biomarkers.

abstract：:The results of experiments are described in which a known quantity of sterile deuterated water is injected directly into the pulmonary circulation via the right internal jugular vein of several haemodialysis patients and the deuterium to hydrogen ratio, D/H, in the exhaled lung water was measured using the flowing aft...

journal_title：Journal of breath research

authors： Tan BK,Davies SJ,Spaněl P,Smith D

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The analysis of volatile organic compounds (VOCs) in breath allows non-invasive investigations of diseases. Animal studies are conducted as a model to perform research of VOCs and their relation to diseases. In large animal models ruminants were often used as experimental targets. The effect of their physiol...

journal_title：Journal of breath research

authors： Oertel P,Küntzel A,Reinhold P,Köhler H,Schubert JK,Kolb J,Miekisch W

更新日期：2018-05-14 00:00:00

abstract：:Reactive oxygen species are associated with tissue inflammation and injury. Our laboratory has demonstrated that ethane, a stable product of lipid peroxidation, in exhaled breath can be used to measure total body oxidative stress. Herein patients were studied who underwent outpatient surgery, laproscopic bilateral tub...

journal_title：Journal of breath research

authors： Brown RH,Risby TH

更新日期：2009-03-01 00:00:00

abstract：:Poor compliance to prescribed medication regimens in clinical trials continues to be a major obstacle to drug development success and cost reduction, and there is no gold standard technology that is cheap and effective to reliably measure drug compliance. This paper presents a new drug compliance scheme based on the d...

journal_title：Journal of breath research

authors： Meka VV,Lutz BJ,Melker RJ,Euliano NR

更新日期：2007-12-01 00:00:00

abstract：:To investigate the premise that levels of endogenous volatile organic compounds (VOC) in breath reflect those in blood, the concentration of acetone and isoprene were measured in radial arterial blood, peripheral venous blood and breath samples from ten healthy volunteers. Coefficients of repeatability as a percentage...

journal_title：Journal of breath research

authors： O'Hara ME,Clutton-Brock TH,Green S,Mayhew CA

更新日期：2009-06-01 00:00:00

abstract：:The data obtained for the concentration distributions of the most abundant volatile metabolites in exhaled breath determined in two independent studies are reviewed, the first limited study involving five healthy volunteers providing daily breath samples over a month, and the subsequent study involving 30 healthy volu...

journal_title：Journal of breath research

authors： Smith D,Turner C,Spaněl P

更新日期：2007-09-01 00:00:00

abstract：:Profiling the body chemistry by means of volatile organic compounds (VOCs) in the breath opens exciting new avenues in medical diagnostics. Gas sensors could provide ideal platforms for realizing portable, hand-held breath testing devices in the near future. This review summarizes the latest developments and applicati...

journal_title：Journal of breath research

authors： Tisch U,Haick H

更新日期：2014-06-01 00:00:00

abstract：:Exhaled NO (FE(NO)) measurements have been utilized as a marker to diagnose asthma as well as a non-invasive tool for monitoring airway inflammation and the response to anti-inflammatory medications. One area where this non-invasive monitoring may be helpful is for asthmatic athletes as they train for competitive even...

journal_title：Journal of breath research

authors： Grob NM,Laskowski D,Dweik RA

更新日期：2008-09-01 00:00:00

abstract：:Tongue coating (TC) mainly consists of protein mostly from exfoliated epithelial cells. Until now, to reduce TC accumulation, only mechanical measures have been available, and the procedure involves unpleasant side effects, such as gagging reflex or carcinogenesis related to mechanical stimulation. We expected that pr...

journal_title：Journal of breath research

authors： Nohno K,Yamaga T,Kaneko N,Miyazaki H

更新日期：2012-03-01 00:00:00

abstract：:Biogenic amines are interesting compounds which may be of use for medical diagnosis or therapeutic monitoring. The present paper deals with the problems that occur with concentration determination of dimethylamine (DMA) and trimethylamine (TMA). These occur in the breath of people suffering from renal disease. The mea...

journal_title：Journal of breath research

authors： Wzorek B,Mochalski P,Sliwka I,Amann A

更新日期：2010-06-01 00:00:00

abstract：:This study aimed to analyze the impact of chewing gum on halitosis parameters. Three databases were searched with the following focused question: 'Can chewing gum additionally reduce halitosis parameters, such as organoleptic scores and volatile sulfur compounds (VSC), when compared to a control treatment'? Controlled...

journal_title：Journal of breath research

authors： Muniz FW,Friedrich SA,Silveira CF,Rösing CK

更新日期：2017-02-17 00:00:00

abstract：:The haloamines, including the chloramines (H(2)NCl, HNCl(2)) and bromamine (H(2)NBr), are diffusible gases that are likely to be produced during inflammation and so may be present as markers of lung inflammation on breath. Although haloamines are quite reactive, it is possible to measure these compounds in humid sampl...

journal_title：Journal of breath research

authors： Storer MK,Dummer JD,Cook J,McEwan M,Epton MJ

更新日期：2011-09-01 00:00:00

abstract：:Oxidative stress is associated with numerous health conditions and disorders, and aldehydes are known biomarkers of oxidative stress that can be non-invasively measured in exhaled human breath. Few studies report breath aldehyde levels in human populations, and none claim participant numbers in the hundreds or more. F...

journal_title：Journal of breath research

authors： McCartney MM,Thompson CJ,Klein LR,Ngo JH,Seibel JD,Fabia F,Simms LA,Borras E,Young BS,Lara J,Turnlund MW,Nguyen AP,Kenyon NJ,Davis CE

更新日期：2020-07-21 00:00:00

abstract：:Sugar malabsorption in the bowel can lead to bloating, cramps, diarrhea and other symptoms of irritable bowel syndrome as well as affecting absorption of other nutrients. The hydrogen breath test is now a well established noninvasive test for assessing malabsorption of sugars in the small intestine. However, there are...

journal_title：Journal of breath research

authors： de Lacy Costello BP,Ledochowski M,Ratcliffe NM

更新日期：2013-06-01 00:00:00

abstract：:In the present longitudinal study, we followed volatile organic compounds (VOCs) excreted in exhaled breath of 20 healthy individuals over time, while adhering to a gluten-free diet for 4 weeks prior to adherence to a normal diet. We used gas chromatography coupled with mass spectrometry (TD-GC-tof-MS) in combination ...

journal_title：Journal of breath research

authors： Baranska A,Tigchelaar E,Smolinska A,Dallinga JW,Moonen EJ,Dekens JA,Wijmenga C,Zhernakova A,van Schooten FJ

更新日期：2013-09-01 00:00:00

abstract：:In this work, we present a hydrophilic self-cleaning condenser surface for the collection of biological and environmental aerosol samples. The condenser is installed in a battery-operated hand-held breath sampling device. The device performance is characterized by the collection and analysis of exhaled breath samples ...

journal_title：Journal of breath research

authors： Zamuruyev KO,Schmidt AJ,Borras E,McCartney MM,Schivo M,Kenyon NJ,Delplanque JP,Davis CE

更新日期：2018-06-08 00:00:00

abstract：:Volatile organic compounds (VOCs) in exhaled breath originate from current or previous environmental exposures (exogenous compounds) and internal metabolic (anabolic and catabolic) production (endogenous compounds). The origins of certain VOCs in breath presumed to be endogenous have been proposed to be useful as prec...

journal_title：Journal of breath research

authors： Pleil JD,Stiegel MA,Risby TH

更新日期：2013-03-01 00:00:00

abstract：:Chronic pulmonary infections are the principal cause of morbidity and mortality in individuals with cystic fibrosis (CF). Due to the polymicrobial nature of these infections, the identification of the particular bacterial species responsible is an essential step in diagnosis and treatment. Current diagnostic procedure...

journal_title：Journal of breath research

authors： Nizio KD,Perrault KA,Troobnikoff AN,Ueland M,Shoma S,Iredell JR,Middleton PG,Forbes SL

更新日期：2016-04-27 00:00:00

abstract：:Leptin plays a key role in obstructive sleep apnea syndrome (OSAS). Leptin production in human airways has been previously evaluated by measuring leptin concentration in the exhaled breath condensate and in the induced sputum. The aim was to study leptin expression in the cells of induced sputum and in exhaled breath ...

journal_title：Journal of breath research

authors： Carpagnano GE,Resta O,Pergola GD,Sabato R,Foschino Barbaro MP

更新日期：2010-09-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD)/emphysema risk groups are well defined and screening allows for early identification of disease. The capability of exhaled volatile organic compounds (VOCs) to detect emphysema, as found by computed tomography (CT) in current and former heavy smokers participating in a lung...

journal_title：Journal of breath research

authors： Cristescu SM,Gietema HA,Blanchet L,Kruitwagen CL,Munnik P,van Klaveren RJ,Lammers JW,Buydens L,Harren FJ,Zanen P

更新日期：2011-12-01 00:00:00

abstract：:Exhaled breath collection is used to identify and monitor inflammatory or oxidative components in breath. Exhaled breath sample collection is noninvasive and would greatly benefit human pollutant exposure research. We demonstrate the efficacy of exhaled breath collection and analysis in two human exposure studies to o...

journal_title：Journal of breath research

authors： Sawyer K,Samet JM,Ghio AJ,Pleil JD,Madden MC

更新日期：2008-09-01 00:00:00

abstract：:Methods for breath sampling and analysis require robust quality assessment to minimise the risk of false discoveries. Planning large-scale multi-site breath metabolite profiling studies also requires careful consideration of systematic and random variation as a result of sampling and analysis techniques. In this study...

journal_title：Journal of breath research

authors： Ahmed WM,Brinkman P,Weda H,Knobel HH,Xu Y,Nijsen TM,Goodacre R,Rattray N,Vink TJ,Santonico M,Pennazza G,Montuschi P,Sterk PJ,Fowler SJ

更新日期：2018-10-30 00:00:00

abstract：:Breath analysis techniques offer a potential revolution in health care diagnostics, especially if these techniques can be brought into standard use in the clinic and at home. The advent of microsensors combined with smart sensor system technology enables a new generation of sensor systems with significantly enhanced c...

journal_title：Journal of breath research

authors： Hunter GW,Xu JC,Biaggi-Labiosa AM,Laskowski D,Dutta PK,Mondal SP,Ward BJ,Makel DB,Liu CC,Chang CW,Dweik RA

更新日期：2011-09-01 00:00:00

abstract：:Breath tests have been used to investigate many physiological functions. Recently, we have developed a breath test system by using a non-invasive technique in conscious rats. In this study, we investigated the effect of atropine sulfate on the gastric emptying and gastrocecal transit time using [1-(13)C]acetic acid an...

journal_title：Journal of breath research

authors： Uchida M,Yoshida K,Shimizu K

更新日期：2009-12-01 00:00:00

abstract：:There is much clinical interest in the development of a low-cost and reliable test for diagnosing inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), two very distinct diseases that can present with similar symptoms. The assessment of stool samples for the diagnosis of gastro-intestinal diseases is in...

journal_title：Journal of breath research

authors： Shepherd SF,McGuire ND,de Lacy Costello BP,Ewen RJ,Jayasena DH,Vaughan K,Ahmed I,Probert CS,Ratcliffe NM

更新日期：2014-06-01 00:00:00

abstract：:Oral malodour is a common condition which affects a large proportion of the population, resulting in social, emotional and psychological stress. Certain oral bacteria form a coating called a biofilm on the tongue dorsum and degrade organic compounds releasing volatile sulfur compounds that are malodourous. Current che...

journal_title：Journal of breath research

authors： Rai M,Spratt D,Gomez-Pereira PR,Patel J,Nair SP

更新日期：2016-10-18 00:00:00

abstract：:Cancer cells prefer hyperglycolysis versus oxidative phosphorylation, even in the presence of oxygen. This phenomenon is used through the FDG-PET scans, and may affect the exhaled volatile signature. This study investigates the volatile signature in lung cancer (LC) before and after an oral glucose tolerance test (OGT...

journal_title：Journal of breath research

authors： Feinberg T,Alkoby-Meshulam L,Herbig J,Cancilla JC,Torrecilla JS,Gai Mor N,Bar J,Ilouze M,Haick H,Peled N

更新日期：2016-06-07 00:00:00

abstract：:Aircraft engine exhaust increases the number concentration of nanoparticles (NP) in the surrounding environment. Health concerns related to NP raise the question of the exposure and health monitoring of airport workers. No biological monitoring study on this profession has been reported to date. The aim was to evaluat...

journal_title：Journal of breath research

authors： Marie-Desvergne C,Dubosson M,Touri L,Zimmermann E,Gaude-Môme M,Leclerc L,Durand C,Klerlein M,Molinari N,Vachier I,Chanez P,Mossuz VC

更新日期：2016-07-13 00:00:00

abstract：:Exhaled breath condensate (EBC) is increasingly being used as a non-invasive method for disease diagnosis and environmental exposure assessment. We previously detected the nucleic acids of bacterial pathogens in EBC. Influenza viruses can be transmitted through aerosols during coughing and exhaling. Existing detection...

journal_title：Journal of breath research

authors： Li X,Wang M,Chen J,Lin F,Wang W

更新日期：2021-01-12 00:00:00

abstract：:Early detection of lung cancer (LC) is a priority since LC is characterized by symptoms mimicking other respiratory conditions, but it remains the leading cause of oncological disease death. Properly trained dogs can perceive the volatile organic compounds (VOCs) related to cancer thanks to their acute sense of smell....

journal_title：Journal of breath research

authors： Mazzola SM,Pirrone F,Sedda G,Gasparri R,Romano R,Spaggiari L,Mariangela A

更新日期：2020-03-11 00:00:00