A novel human antimicrobial factor targets Pseudomonas aeruginosa through its type III secretion system.

abstract：:Nosocomial infections with enterococci are an increasing problem in modern medical practice due to the development of resistance to a wide range of antibiotics, including the glycopeptides vancomycin and teicoplanin. An increasing number of vancomycin-resistant enterococci (VRE) have been cultured from clinical specim...

journal_title：Journal of medical microbiology

authors： Mackenzie CR,Hucke C,MÜller D,Seidel K,Takikawa O,DÄubener W

更新日期：1999-10-01 00:00:00

abstract：:Clostridium difficile is a frequent cause of severe, recurrent, post-antibiotic diarrhoea and pseudomembranous colitis. Its pathogenicity is mediated mainly by two toxins, TcdA and TcdB. However, different adhesins have also been described as important colonization factors which are implicated in the first step of the...

journal_title：Journal of medical microbiology

authors： Barketi-Klai A,Hoys S,Lambert-Bordes S,Collignon A,Kansau I

更新日期：2011-08-01 00:00:00

abstract：:In the present study, the adhesion of bacteriocin-producing probiotic strains of Lactobacillus plantarum onto extracellular matrix (ECM) proteins such as collagen and mucin and their potential to prevent pathogen invasion onto the ECM was ascertained. Fluorescence-based in vitro assays indicated that L. plantarum stra...

journal_title：Journal of medical microbiology

authors： Mukherjee S,Ramesh A

更新日期：2015-12-01 00:00:00

abstract：:A total of 817 human clinical isolates of Clostridium difficile from all Australian states were screened for A(-)B(+) strains by toxin gene PCR assays. Nine (1.1 %) strains were confirmed to be A(-)B(+) by enzyme immunoassay for toxin production. Of these, six (66.7 %) were binary toxin-positive by PCR. Using PCR ribo...

journal_title：Journal of medical microbiology

authors： Elliott B,Squire MM,Thean S,Chang BJ,Brazier JS,Rupnik M,Riley TV

更新日期：2011-08-01 00:00:00

abstract：:Fusarium spp. and other non-dermatophyte fungi are repeatedly isolated from abnormal nails. To investigate whether these fungi are the aetiological agents of infection or simply transient contaminants, a PCR/sequencing/RFLP assay was developed for direct and routine identification of the infecting fungi in onychomycos...

journal_title：Journal of medical microbiology

authors： Monod M,Bontems O,Zaugg C,Léchenne B,Fratti M,Panizzon R

更新日期：2006-09-01 00:00:00

abstract：:EDTA-released outer-membrane antigen complexes were prepared from 172 laboratory and reference strains and 43 fresh clinical or faecal isolates representing 20 species or subspecies of Bacteroides, together with 13 species of other genera. These antigens were titrated against antisera to whole, live cells of 21 specie...

journal_title：Journal of medical microbiology

authors： Poxton IR,Brown R,Collee JG

更新日期：1982-05-01 00:00:00

abstract：:Bacterial invasion of host epithelial cells plays an important role in the pathogenesis of periodontal diseases; however, the interactions between subgingival species and the gingival crevice cells are not fully understood. This study determined the prevalence of a group of oral bacterial species on or in epithelial c...

journal_title：Journal of medical microbiology

authors： Colombo AV,Silva CM,Haffajee A,Colombo APV

更新日期：2006-05-01 00:00:00

abstract：:Serology remains the mainstay for diagnosis of Epstein-Barr virus (EBV) infection. This study compared two automated platforms (BioPlex 2200 and Architect i2000SR) to test three EBV serological markers: viral capsid antigen (VCA) immunoglobulins of class M (IgM), VCA immunoglobulins of class G (IgG) and EBV nuclear an...

journal_title：Journal of medical microbiology

authors： Al Sidairi H,Binkhamis K,Jackson C,Roberts C,Heinstein C,MacDonald J,Needle R,Hatchette TF,LeBlanc JJ

更新日期：2017-11-01 00:00:00

abstract：:A solid-phase radioimmunoassay was used to detect IgG antibodies against herpes-simplex virus antigens (capsid, envelope and excreted) and against measles virus antigen in serum and cerebrospinal fluid (CSF) specimens of 61 patients with no evidence of infectious or demyelinating disease of the central nervous system....

journal_title：Journal of medical microbiology

authors： Kalimo KO,Marttila RJ,Ziola BR,Matikainen MT,Panelius M

更新日期：1977-11-01 00:00:00

abstract：:Acinetobacter junii is a rare human pathogen associated with bacteraemia in neonates and paediatric oncology patients. We present a case of A. junii causing bacteraemia in an adult transplant patient with leukaemia. The correct identification of Acinetobacter species can highlight the clinical significance of the diff...

journal_title：Journal of medical microbiology

authors： Cayô R,Yañez San Segundo L,Pérez Del Molino Bernal IC,García de la Fuente C,Bermúdez Rodríguez MA,Calvo J,Martínez-Martínez L

更新日期：2011-03-01 00:00:00

abstract：:The Gen-Probe APTIMA Combo 2 assay has previously been reported to have a high sensitivity. The end point of this assay was evaluated using highly purified chlamydial elementary bodies (EBs). The performance of the APTIMA Combo 2 assay was compared with a commercially available PCR kit, AMPLICOR Chlamydia trachomatis....

journal_title：Journal of medical microbiology

authors： Ikeda-Dantsuji Y,Konomi I,Nagayama A

更新日期：2005-04-01 00:00:00

abstract：PURPOSE:Persister cells, a subpopulation of tolerant cells within the bacterial culture, are commonly thought to be responsible for antibiotic therapy failure and infection recurrence. Klebsiella pneumoniae is a notorious human pathogen for its increasing resistance to antibiotics and wide involvement in severe infecti...

journal_title：Journal of medical microbiology

authors： Li Y,Zhang L,Zhou Y,Zhang Z,Zhang X

更新日期：2018-03-01 00:00:00

abstract：:Candida albicans is the species most frequently isolated from oral specimens, but the recovery of other Candida species such as Candida dubliniensis is increasing. Differentiation of C. dubliniensis from C. albicans requires special tests and both species are misidentified in some studies. CHROM-Pal (CH-P) is a novel ...

journal_title：Journal of medical microbiology

authors： Sahand IH,Maza JL,Eraso E,Montejo M,Moragues MD,Aguirre JM,Quindós G,Pontón J

更新日期：2009-11-01 00:00:00

abstract：:Yersinia pseudotuberculosis was examined for its haemagglutinating activity and adherence to cultured epithelial cells (HEp-2) in relation to possession of a virulence (VW) plasmid and to growth conditions. VW-lacking (VW-) bacteria were isolated from ten VW+ strains of each serovar which, after they were grown on CFA...

journal_title：Journal of medical microbiology

authors： Kawaoka Y,Mitani T,Hoshina K,Otsuki K,Tsubokura M

更新日期：1988-03-01 00:00:00

abstract：:The purpose of this study was to evaluate the anti-chlamydial activities in vitro of liposome-encapsulated doxycycline (Dox) and tetracycline (Tet) in comparison with free Dox and Tet. Dox and Tet encapsulated in cationic (CAL), anionic (ANL) and neutral (NTL) liposomes by sonication, were quantified by high-performan...

journal_title：Journal of medical microbiology

authors： Sangare L,Morisset R,Ravaoarinoro M

更新日期：1999-07-01 00:00:00

abstract：:Circulating immune complexes (ICs) containing IgG and HBsAg, and IgG and HBeAg, in sera from groups of patients with various liver diseases were sought by ELISA and immunodiffusion. A correlation was found between the absence of ICs and the disappearance of HBsAg in patients who had recovered from acute hepatitis B, b...

journal_title：Journal of medical microbiology

authors： Leyva A,Bernal MC,Piedrola G,Maroto MC

更新日期：1988-07-01 00:00:00

abstract：:Gardnerella vaginalis is a Gram-variable anaerobic bacterium present in 100% of women with bacterial vaginosis (BV). BV is a complex polymicrobial condition with no single causative agent. The current laboratory detection method for BV relies on a Gram-stain Nugent score to estimate the quantity of different bacterial...

journal_title：Journal of medical microbiology

authors： Cox C,McKenna JP,Watt AP,Coyle PV

更新日期：2015-09-01 00:00:00

abstract：:Borderline oxacillin-resistant Staphylococcus aureus (BORSA) represents a quite poorly understood and inadequately defined phenotype of methicillin resistance. BORSA strains show low, borderline resistance to penicillinase-resistant penicillins (PRPs), with oxacillin MICs typically equal to 1-8 µg ml-1, and in contras...

journal_title：Journal of medical microbiology

authors： Hryniewicz MM,Garbacz K

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:Diabetic patients seem to be predisposed to cutaneous candidiasis. In this study, we evaluated the interference of diabetic conditions in alloxan-induced diabetic mice in relation to the development of C. albicans infection, density of M1 and M2 macrophages, distribution of collagen type I and III and anti-infl...

journal_title：Journal of medical microbiology

authors： Pupim ACE,Campois TG,Araújo EJA,Svidizinski TIE,Felipe I

更新日期：2017-06-01 00:00:00

abstract：:In-vitro proteinase production by oral Candida albicans isolates from patients with and without HIV infection (18 isolates from each group) was assessed by image analysis of a plate assay, with bovine serum albumin (BSA) as a substrate. The effect of sub-minimal inhibitory concentrations (sub-MICs) of nystatin, amphot...

journal_title：Journal of medical microbiology

authors： Wu T,Samaranayake LP,Cao BY,Wang J

更新日期：1996-04-01 00:00:00

abstract：:Acinetobacter baumannii is an emerging multidrug-resistant pathogen and very little information is available regarding its imipenem resistance in Latin American countries such as Bolivia. This study investigated the antimicrobial resistance profile of 46 clinical strains from different hospitals in Cochabamba, Bolivia...

journal_title：Journal of medical microbiology

authors： Sevillano E,Fernández E,Bustamante Z,Zabalaga S,Rosales I,Umaran A,Gallego L

更新日期：2012-01-01 00:00:00

abstract：:Bovine lactoferricin, a pepsin-generated antimicrobial peptide from bovine lactoferrin active against a wide range of bacteria, was tested for its ability to influence the adhesion and invasion of Yersinia enterocolitica and Yersinia pseudotuberculosis in HEp-2 cells. The addition of non-cytotoxic and non-bactericidal...

journal_title：Journal of medical microbiology

authors： Di Biase AM,Tinari A,Pietrantoni A,Antonini G,Valenti P,Conte MP,Superti F

更新日期：2004-05-01 00:00:00

abstract：:Molecular typing is an important tool for control and prevention of infection. A suitable molecular typing method for epidemiological investigation must be easy to perform, highly reproducible, inexpensive, rapid and easy to interpret. In this study, two molecular typing methods including the conventional PCR-sequenci...

journal_title：Journal of medical microbiology

authors： Fasihi Y,Fooladi S,Mohammadi MA,Emaneini M,Kalantar-Neyestanaki D

更新日期：2017-09-01 00:00:00

abstract：:The eubacterial population was studied in faecal samples of related and unrelated children. Temporal temperature gradient gel electrophoresis (TTGE) provided a snapshot of the bacterial population and allowed calculation of the degree of similarity in the predominant faecal microflora of identical twin pairs, fraterna...

journal_title：Journal of medical microbiology

authors： Stewart JA,Chadwick VS,Murray A

更新日期：2005-12-01 00:00:00

abstract：PURPOSE:The objective of the present study is to investigate the diverse resistance determinants, their association with insertion sequence mobile elements and predilection of a particular clone for such associations in Acinetobacter baumannii. METHODOLOGY:Fifty-four consecutive isolates collected during 2011-2012 fro...

journal_title：Journal of medical microbiology

authors： Saranathan R,Kumari R,Kalaivani R,Suresh S,Rani A,Purty S,Prashanth K

更新日期：2017-03-01 00:00:00

abstract：:Staphylococcus aureus produces numerous bi-component toxins, e.g., Panton-Valentine leukocidin (Luk-PVL) and gamma-haemolysin, which consist of type S and F proteins. Previous studies showed that Luk-PVL induces inflammatory mediator release from human granulocytes that might reflect the in-vivo effects, e.g., dermone...

journal_title：Journal of medical microbiology

authors： König B,Prévost G,König W

更新日期：1997-06-01 00:00:00

abstract：:Two isogenic sets of Yersinia pestis strains were generated, composed of wild-type strains 231 and I-1996, their non-polar pH 6(-) mutants with deletions in the psaA gene that codes for its structural subunit or the whole operon, as well as strains with restored ability for temperature- and pH-dependent synthesis of a...

journal_title：Journal of medical microbiology

authors： Anisimov AP,Bakhteeva IV,Panfertsev EA,Svetoch TE,Kravchenko TB,Platonov ME,Titareva GM,Kombarova TI,Ivanov SA,Rakin AV,Amoako KK,Dentovskaya SV

更新日期：2009-01-01 00:00:00

abstract：:The gingival sulcus is the shallow crevice around the tooth, and its epithelium is a gateway for initial bacterial infection in periodontal disease. Recent studies have shown that Actinobacillus actinomycetemcomitans invades an epithelial cell line, KB cells, in vitro. The aim of the present study was to clarify the c...

journal_title：Journal of medical microbiology

authors： Kato S,Nakashima K,Inoue M,Tomioka J,Nonaka K,Nishihara T,Kowashi Y

更新日期：2000-08-01 00:00:00

abstract：:The relationship between vaginal carriage and subsequent neonatal acquisition of Clostridium difficile was investigated. Vaginal carriage of C. difficile was detected in 11% of women attending the Department of Genital Medicine Clinic. C. difficile was isolated from the vagina in 18% of 50 mothers before delivery, and...

journal_title：Journal of medical microbiology

authors： Tabaqchali S,O'Farrell S,Nash JQ,Wilks M

更新日期：1984-08-01 00:00:00

abstract：:The abilities of six strains of Salmonella typhimurium to associate with rabbit ileal mucosa have been measured in vitro. Two were "virulent" strains (TML and W118 which are invasive and inducers of fluid secretion in rabbit ileal loops); four were "avirulent" (LT7, M206 and SL1027 which are invasive but induce neglig...

journal_title：Journal of medical microbiology

authors： Worton KJ,Candy DC,Wallis TS,Clarke GJ,Osborne MP,Haddon SJ,Stephen J

更新日期：1989-08-01 00:00:00