Utilizing conformational changes for patterning thin films of recombinant spider silk proteins.

abstract：:The copolymer of methyl methacrylate (MMA) and 2-[2',3',5'-triiodobenzoyl]oxoethyl methacrylate (1), ratio 3:1 (mass:mass), was prepared via a free-radical polymerization in bulk. The copolymer (M(w) = 97.8 kD and M(n) = 41.5 kD) was dissolved in chloroform and subsequently transformed into beads with a diameter in th...

journal_title：Biomacromolecules

authors： Saralidze K,Aldenhoff YB,Knetsch ML,Koole LH

更新日期：2003-05-01 00:00:00

abstract：:Tumorigenic cell behaviors can be suppressed or enhanced by their physicochemical environment. As a first step toward developing materials that allow tumorigenic behaviors to be observed and manipulated, we cultured related MCF10 breast cell lines on fibers composed of the Drosophila protein Ultrabithorax (Ubx). These...

journal_title：Biomacromolecules

authors： Hsiao HC,Santos A,Howell DW,Patterson JL,Fuchs-Young RS,Bondos SE

更新日期：2016-11-14 00:00:00

abstract：:Hydrogel fibers that possessed a cell-adhesive surface and were degradable via enzymatic reactions were developed for fabricating tubular constructs with smooth muscle cell (SMC) and endothelial cell (EC) layers, similar to native blood vessels, in collagen gels. The fibers were prepared by soaking hydrogel fibers pre...

journal_title：Biomacromolecules

authors： Sakai S,Yamaguchi S,Takei T,Kawakami K

更新日期：2008-07-01 00:00:00

abstract：:Chimeric DNA containing parallel (ps) and antiparallel (aps) duplex elements as well as poly-dC tracts were designed and synthesized. Oligonucleotide duplexes with ps chain orientation containing reverse Watson-Crick dA-dT base pairs and short d(C)2 tails are stabilized under slightly acidic conditions by hemiprotonat...

journal_title：Biomacromolecules

authors： Mei H,Budow S,Seela F

更新日期：2012-12-10 00:00:00

abstract：:This study is devoted to developing amphiphilic block polymers based on phenylborate ester, which can self-assemble to form nanoparticles, as a glucose-sensitive drug carrier. Poly(ethylene glycol)-block-poly[(2-phenylboronic esters-1,3-dioxane-5-ethyl) methylacrylate] (MPEG5000-block-PBDEMA) was fabricated with MPEG5...

journal_title：Biomacromolecules

authors： Yao Y,Zhao L,Yang J,Yang J

更新日期：2012-06-11 00:00:00

abstract：:A novel approach for the preparation of nano- and microcapsules in aqueous solutions by using thermoresponsive polymer (TRP) templates (mesoglobules) is described. The method comprised three steps: formation of mesoglobules, coating the templates by seeded radical copolymerization, followed by core dissolution and cor...

journal_title：Biomacromolecules

authors： Haladjova E,Toncheva-Moncheva N,Apostolova MD,Trzebicka B,Dworak A,Petrov P,Dimitrov I,Rangelov S,Tsvetanov CB

更新日期：2014-12-08 00:00:00

abstract：:Major ampullate silk, also known as dragline silk, is one of the strongest biomaterials known. This silk is composed of two proteins, major ampullate spidroin 1 (MaSp1) and major ampullate spidroin 2 (MaSp2). Only partial cDNA sequences have been obtained for these proteins, and these sequences are toward the C-termin...

journal_title：Biomacromolecules

authors： Motriuk-Smith D,Smith A,Hayashi CY,Lewis RV

更新日期：2005-11-01 00:00:00

abstract：:Presently there is great interest in the construction of nanostructures from DNA fragments. Here we report the preparation of much larger helical textures with different shapes from pure DNA fragments. We have observed them while preparing crystals of the dodecamer d(AAAAAATTTTTT), which only contains adenine and thym...

journal_title：Biomacromolecules

authors： Subirana JA,Creixell M,Baldini R,Campos JL

更新日期：2008-01-01 00:00:00

abstract：:This paper shows a simple and effective way to avoid the dissociation of multimeric enzymes by coating their surface with a large cationic polymer (e.g., polyethylenimine (PEI)) by ionic exchange. As model enzymes, glutamate dehydrogenase (GDH) from Thermus thermophilus and formate dehydrogenase (FDH) from Pseudomonas...

journal_title：Biomacromolecules

authors： Bolivar JM,Rocha-Martin J,Mateo C,Cava F,Berenguer J,Fernandez-Lafuente R,Guisan JM

更新日期：2009-04-13 00:00:00

abstract：:Hydrogels are supramolecular assemblies with both solute transport properties like liquids and mechanical properties like elastomers. To date, every type of biomolecules except ribonucleic acid (RNA), is capable of forming a hydrogel. Here, we report an RNA that forms a hydrogel by self-assembly. This RNA is originall...

journal_title：Biomacromolecules

authors： Huang Z,Kangovi GN,Wen W,Lee S,Niu L

更新日期：2017-07-10 00:00:00

abstract：:Prevention of biofouling and microbial contamination of implanted biomedical devices is essential to maintain their functionality and biocompatibility. For this purpose, polypept(o)ide block copolymers have been developed, in which a protein-resistant polysarcosine (pSar) block is combined with a dopamine-modified pol...

journal_title：Biomacromolecules

authors： Yoo J,Birke A,Kim J,Jang Y,Song SY,Ryu S,Kim BS,Kim BG,Barz M,Char K

更新日期：2018-05-14 00:00:00

abstract：:A one-step synthesis of a curcumin-derived hydrogel (curcumin content of 25-75 mol %) is reported. Curcumin is incorporated into the hydrogel backbone and cross-linked through biodegradable carbonate linkages. Curcumin as a part of the polymer backbone is protected from oxidation and degradation, while hydrogel hydrol...

journal_title：Biomacromolecules

authors： Shpaisman N,Sheihet L,Bushman J,Winters J,Kohn J

更新日期：2012-08-13 00:00:00

abstract：:In this contribution, a hydrophobically modified polysaccharide derivative is synthesized in an eco-friendly solvent water by conjugation of benzylamine with the backbone of the biopolymer. Owing to the presence of aromatic moieties, the resulting water-soluble polysaccharide derivative self-assembles spontaneously an...

journal_title：Biomacromolecules

authors： Mohan T,Rathner R,Reishofer D,Koller M,Elschner T,Spirk S,Heinze T,Stana-Kleinschek K,Kargl R

更新日期：2015-08-10 00:00:00

abstract：:We demonstrate the fabrication of protein·gold nanoparticle (AuNP) nanocomposites in situ, leading to distinct assemblies dependent upon protein secondary structure. In the presence of pentameric coiled-coil proteins C and Q, which contain histidine tags and have helicities of 54 and 65%, respectively, templation of A...

journal_title：Biomacromolecules

authors： Hume J,Chen R,Jacquet R,Yang M,Montclare JK

更新日期：2015-06-08 00:00:00

abstract：:The effect of guluronate oligomers on the barrier properties of mucous matrices was investigated in terms of the mobility of nanoparticles in mucous matrices by fluorescence recovery after photobleaching (FRAP), cellular uptake of nanoparticles in mucus secreting cells (HT29-MTX), and mucin matrix architecture by scan...

journal_title：Biomacromolecules

authors： Nordgård CT,Nonstad U,Olderøy MØ,Espevik T,Draget KI

更新日期：2014-06-09 00:00:00

abstract：:The manufacture of biodegradable materials from agricultural sources is a real challenge, because of environmental concerns and the need to make full use of resources. Cottonseed is an important protein source that could be used in nonfood applications, as a substitute for synthetic polymers. For the first time, the v...

journal_title：Biomacromolecules

authors： Grevellec J,Marquié C,Ferry L,Crespy A,Vialettes V

更新日期：2001-01-01 00:00:00

abstract：:Poly(epsilon-caprolactone)/polylactide blend (PCL/PLA) is an interesting biomaterial because PCL and PLA present good complementarity in their physical properties and biodegradability. However, the thermodynamic incompatibility between two component polymers restricts further applications of their blend. In this work,...

journal_title：Biomacromolecules

authors： Wu D,Zhang Y,Zhang M,Yu W

更新日期：2009-02-09 00:00:00

abstract：:As an aim toward developing biologically mimetic and functional nanofiber-based tissue engineering scaffolds, we demonstrated the encapsulation of a model protein, fluorescein isothiocyanate-conjugated bovine serum albumin (fitcBSA), along with a water-soluble polymer, poly(ethylene glycol) (PEG), within the biodegrad...

journal_title：Biomacromolecules

authors： Zhang YZ,Wang X,Feng Y,Li J,Lim CT,Ramakrishna S

更新日期：2006-04-01 00:00:00

abstract：:Forisomes are protein polymers found in leguminous plants that have the remarkable ability to undergo reversible "muscle-like" contractions in the presence of divalent cations and in extreme pH environments. To gain insight into the molecular basis of forisome structure and assembly, we used confocal laser scanning mi...

journal_title：Biomacromolecules

authors： Groscurth S,Müller B,Schwan S,Menzel M,Diekstall F,Senft M,Kendall A,Kommor BA,Neumann U,Kalischuk M,Kawchuk LM,Krzyzanek V,Heilmann A,Stubbs G,Twyman RM,Prüfer D,Noll GA

更新日期：2012-10-08 00:00:00

abstract：:We report a robust method to manufacture polyacrylamide-based functional hydrogel microspheres with readily tunable macroporous structures by utilizing a simple micromolding-based technique. Specifically, surface tension-induced droplet formation of aqueous solutions of chitosan and acrylamide in 2D-shaped micromolds ...

journal_title：Biomacromolecules

authors： Jung S,Abel JH,Starger JL,Yi H

更新日期：2016-07-11 00:00:00

abstract：:Reductively degradable biopolymers have emerged as a unique class of smart biomedical materials. Here, a functional coupling agent, cystamine diisocyanate (CDI), was designed to offer a facile access to reductively degradable biopolymers via polycondensation with various diols. CDI was readily obtained with a decent y...

journal_title：Biomacromolecules

authors： Wang X,Zhang J,Cheng R,Meng F,Deng C,Zhong Z

更新日期：2016-03-14 00:00:00

abstract：:Dragline silk from orb-weaving spiders is a copolymer of two large proteins, major ampullate spidroin 1 (MaSp1) and 2 (MaSp2). The ratio of these proteins is known to have a large variation across different species of orb-weaving spiders. NMR results from gland material of two different species of spiders, N. clavipe...

journal_title：Biomacromolecules

authors： An B,Jenkins JE,Sampath S,Holland GP,Hinman M,Yarger JL,Lewis R

更新日期：2012-12-10 00:00:00

abstract：:Chitosan fibers showing narrow diameter distribution with a mean of 42 nm were produced by electrospinning and utilized for the sorption of Fe(III), Cu(II), Ag(I), and Cd(II) ions from aqueous solutions. The ion concentrations in the supernatant solutions were determined using inductively coupled plasma-mass spectrome...

journal_title：Biomacromolecules

authors： Horzum N,Boyaci E,Eroğlu AE,Shahwan T,Demir MM

更新日期：2010-12-13 00:00:00

abstract：:Antibacterial nanodevices could bring coatings of plastic materials and wound dressings a big step forward if the release of the antibacterial agents could be triggered by the presence of the bacteria themselves. Here, we show that novel hyaluronic acid (HA)-based nanocapsules containing the antimicrobial agent polyhe...

journal_title：Biomacromolecules

authors： Baier G,Cavallaro A,Vasilev K,Mailänder V,Musyanovych A,Landfester K

更新日期：2013-04-08 00:00:00

abstract：:We examine the protein distribution within an electrospun polymer nanofiber using polyvinyl alcohol and bovine serum albumin as a model system. We hypothesize that the location of the protein within the nanofiber can be controlled by carefully selecting the pH and the applied polarity of the electric field as the pH a...

journal_title：Biomacromolecules

authors： Tang C,Ozcam AE,Stout B,Khan SA

更新日期：2012-05-14 00:00:00

abstract：:The interaction of polysaccharides with water has a critical impact on their biological function as well as their technological applications. We performed ellipsometry experiments at different relative humidities (RH) to measure the equilibrium swelling of ultrathin films of different polysaccharides: native and modif...

journal_title：Biomacromolecules

authors： Grossutti M,Dutcher JR

更新日期：2020-12-14 00:00:00

abstract：:X-ray analytical techniques are increasingly being used to study manuscripts and works of art on paper, whether with laboratory equipment or synchrotron sources. However, it is difficult to anticipate the impact of X-ray photons on paper- and cellulose-based artifacts, particularly due to the large variety of their co...

journal_title：Biomacromolecules

authors： Gimat A,Schöder S,Thoury M,Missori M,Paris-Lacombe S,Dupont AL

更新日期：2020-07-13 00:00:00

abstract：:The nonapeptide hemopressin, which is derived from the α chain of hemoglobin, has been reported to exhibit inverse agonist activity against the CB1 receptor. Administration of this peptide in animal models led to decreased food intake and elicited hypotensive and antinociceptive effects. On the basis of hemopressin's ...

journal_title：Biomacromolecules

authors： Bomar MG,Samuelsson SJ,Kibler P,Kodukula K,Galande AK

更新日期：2012-03-12 00:00:00

abstract：:This paper presents the formation of a novel biomimetic interface consisting of an electrolessly deposited gold film overlaid with a tethered bilayer lipid membrane (tBLM). Self-assembly of colloidal gold particles was used to create an electrolessly deposited gold film on a glass slide. The properties of the film wer...

journal_title：Biomacromolecules

authors： Kohli N,Hassler BL,Parthasarathy L,Richardson RJ,Ofoli RY,Worden RM,Lee I

更新日期：2006-12-01 00:00:00

abstract：:Water-soluble T-antigen containing glycopolymers [Gal beta(1,3)-GalNAc alpha) having a high degree of lipophilicity were synthesized from poly[N-(acryloxy)succinimide] (6-10) by amidation with an amine-ending T-antigen derivative (3) and various amines of increasing alkyl chain length (ammonia and methyl-, ethyl-, and...

journal_title：Biomacromolecules

authors： Baek MG,Roy R

更新日期：2000-01-01 00:00:00