Abstract:
OBJECTIVE:Glomerular filtration rate (GFR) is part of routine medical practice for clinical assessment of kidney function in health and disease conditions, and is determined by measuring the clearance of creatinine (Cl-Crn) or estimated (eGFR) from equations using serum creatinine (Crn) or cystatin C (Cyst C). Crn and Cyst C methods obviate the need for urine collection but their reliability under non-resting conditions is uncertain. This study compared GFR determined by Cl-Crn, Crn and Cyst C methods under the conditions of rest and after exercise. METHODS:Twelve young male subjects performed a 30 min treadmill exercise at 80% of the maximal oxygen capacity. Venous blood samples and urine collections were collected before and after exercise and after recovery period. GFR rates were calculated from serum Crn and Cyst C equations, and Cl-Crn measured from serum and urine Crn output. Albumin was also determined for all samples. RESULTS:Under resting conditions, eGFR from Crn and Cyst C did not differ from Cl-Crn (p=0.39). Immediately after exercise, GFR decreased significantly, regardless of the method, but more so for Cl-Crn (-30.0%; p<0.05) compared with Crn (-18.2%) and Cyst C (-19.8%). After the recovery period, GFR determined by Cl-Crn was returned to initial values whereas Crn and Cyst C remained reduced. Although eGFR methods accurately estimate GFR at rest, those methods underestimated the change in GFR after acute exercise. CONCLUSIONS:These results indicate that exercise-induced changes in GFR should be determined by Cl-Crn method.
journal_name
Br J Sports Medjournal_title
British journal of sports medicineauthors
Poortmans JR,Gulbis B,De Bruyn E,Baudry S,Carpentier Adoi
10.1136/bjsports-2012-090976subject
Has Abstractpub_date
2013-12-01 00:00:00pages
1166-70issue
18eissn
0306-3674issn
1473-0480pii
bjsports-2012-090976journal_volume
47pub_type
杂志文章abstract::Data on tolerance of cardiac pacemakers during diving are very scarce. The aim of this study was to test electronic and mechanical tolerances of pacemakers exposed to experimental reproductions of pressures encountered during diving. Two samples each of 20 different models of cardiac pacemakers were exposed to compres...
journal_title:British journal of sports medicine
pub_type: 杂志文章
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更新日期:2008-03-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章,meta分析,评审
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journal_title:British journal of sports medicine
pub_type: 临床试验,杂志文章
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journal_title:British journal of sports medicine
pub_type: 杂志文章,meta分析,评审
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更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:The ability to predict injury is difficult. Prior injury is the only risk factor that has been reported consistently in multiple research studies. Convenient and easy to perform, physical performance tests (PPTs) have great allure as prognostic factors. METHODS:11 PPTs were issued to 359 participants over t...
journal_title:British journal of sports medicine
pub_type: 杂志文章
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更新日期:2016-11-01 00:00:00
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journal_title:British journal of sports medicine
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doi:10.1136/bjsm.16.1.13
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journal_title:British journal of sports medicine
pub_type: 临床试验,杂志文章
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journal_title:British journal of sports medicine
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更新日期:2011-04-01 00:00:00
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doi:10.1136/bjsm.30.4.347
更新日期:1996-12-01 00:00:00
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journal_title:British journal of sports medicine
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doi:10.1136/bjsm.2008.047449
更新日期:2010-02-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.2006.027532
更新日期:2006-07-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 临床试验,杂志文章
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更新日期:2002-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1136/bjsm.19.4.199
更新日期:1985-12-01 00:00:00
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doi:10.1136/bjsm.2006.027276
更新日期:2006-09-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsports-2012-091103
更新日期:2014-06-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1136/bjsports-2016-096605
更新日期:2018-02-01 00:00:00
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journal_title:British journal of sports medicine
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更新日期:2009-08-01 00:00:00
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pub_type: 杂志文章
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journal_title:British journal of sports medicine
pub_type: 临床试验,杂志文章
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更新日期:1999-10-01 00:00:00
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journal_title:British journal of sports medicine
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更新日期:2010-09-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2014-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1136/bjsm.31.2.143
更新日期:1997-06-01 00:00:00
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pub_type: 共识发展会议,杂志文章
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更新日期:2020-10-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章,随机对照试验
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更新日期:2008-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2004-06-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章
doi:10.1136/bjsm.33.4.255
更新日期:1999-08-01 00:00:00