Association of white blood cell subfraction concentration with fitness and fatness.

Abstract:

OBJECTIVE:To examine the association between fitness, BMI, and neutrophil, lymphocyte, monocyte, basophil, and eosinophil concentrations in apparently healthy, non-smoking men. DESIGN:Cross-sectional study of 452 men from the Aerobics Center Longitudinal Study examining the resting concentration of white blood cell subfractions across fitness (maximal METs during a treadmill exercise test) and fatness (BMI) categories after adjusting for age. RESULTS:Fitness was inversely associated with all WBC subfraction concentrations. After further adjustment for BMI, only total WBC, neutrophil, and basophil concentrations remained significantly associated with fitness. BMI was directly associated with total WBC, neutrophil, lymphocyte, monocyte, and basophil concentrations and, when fitness was added to the model, only monocytes lost significance. CONCLUSION:Fitness (inversely) and fatness (directly) are associated with WBC subfraction populations.

journal_name

Br J Sports Med

authors

Johannsen NM,Priest EL,Dixit VD,Earnest CP,Blair SN,Church TS

doi

10.1136/bjsm.2008.050682

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

588-93

issue

8

eissn

0306-3674

issn

1473-0480

pii

bjsm.2008.050682

journal_volume

44

pub_type

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