Abstract:
:Astrocyte-neuron communication has recently been proposed as a potential mechanism participating to synaptic transmission. With the development of this concept and accumulating evidences in favor of a modulation of synaptic transmission by astrocytes, has emerged the term gliotransmission. It refers to the capacity of astrocytes to release various transmitters, such as ATP, glutamate, D-serine, and GABA in the vicinity of synapses. While the cellular mechanisms involved in gliotransmission still need to be better described and, for some, identified, the aim of more and more studies is to determine the role of astrocytes from a functional point of view. This review will summarize the principal studies that have investigated a potential role of astrocytes in the various functions regulated by the brain (sleep, breathing, perception, learning and memory…). This will allow us to highlight the similarities and discrepancies in the signaling pathways involved in the different areas of the brain related to these functions.
journal_name
Neurochem Resjournal_title
Neurochemical researchauthors
Ben Achour S,Pascual Odoi
10.1007/s11064-012-0807-0subject
Has Abstractpub_date
2012-11-01 00:00:00pages
2464-73issue
11eissn
0364-3190issn
1573-6903journal_volume
37pub_type
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journal_title:Neurochemical research
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journal_title:Neurochemical research
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doi:10.1007/s11064-012-0915-x
更新日期:2013-02-01 00:00:00
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更新日期:2008-02-01 00:00:00
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doi:10.1007/s11064-018-2595-7
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journal_title:Neurochemical research
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abstract::N-Acetylaspartic and N-acetylaspartylglutamic acid concentrations in human ventricular, subarachnoid and lumbar cerebrospinal fluid were measured by combined gas chromatography-mass spectrometry using selected ion monitoring with deuterated internal standards. N-Acetylaspartate concentrations were in the range 55, 9, ...
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