Abstract:
:Here, we describe four cases of laboratory-confirmed Legionella infection. Case 1 was a culture-confirmed case of Legionella infection in a patient with liver cirrhosis. Following this, three other liver cirrhosis cases (cases 2-4) were diagnosed with Legionella infection as confirmed by quantitative real-time PCR. The cause of the pneumonia was determined as Legionella pneumophila by positive direct fluorescence assay and isolation of the causative agent. The infections were successfully treated by administering appropriate antibiotics. These cases highlight the importance of considering Legionella as a cause of pneumonia in patients with liver disease and lung infections. The strain of L. pneumophila isolated from Case 1 was characterized as being closely related to strain Philadelphila-1 (ATCC 33152(T)), which is the type strain of the species, belonging to serogroup 1 and sequence type 36 (ST36), and is known to be distributed worldwide. To our knowledge, this is the first report of Legionella infection on the Chinese mainland for a decade and highlights the need to raise awareness of diagnostic methods for Legionnaires' disease in China and the requirement for further epidemiological surveillance strategies to monitor this disease.
journal_name
J Med Microbioljournal_title
Journal of medical microbiologyauthors
Qin T,Xia J,Ren H,Zhou H,Tang B,Shao Zdoi
10.1099/jmm.0.040170-0subject
Has Abstractpub_date
2012-07-01 00:00:00pages
1023-1028issue
Pt 7eissn
0022-2615issn
1473-5644journal_volume
61pub_type
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journal_title:Journal of medical microbiology
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更新日期:2013-06-01 00:00:00
abstract::The relationship between vaginal carriage and subsequent neonatal acquisition of Clostridium difficile was investigated. Vaginal carriage of C. difficile was detected in 11% of women attending the Department of Genital Medicine Clinic. C. difficile was isolated from the vagina in 18% of 50 mothers before delivery, and...
journal_title:Journal of medical microbiology
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