Transferring knowledge towards understanding the pore stabilizing variations in K(+) channels: pore stability in K(+) channels.

abstract：:The importance of crucial nutrient factors like Phosphate (P) and their limited availability leads to variable fluctuations in fatty acid and phospholipid synthesis in the green alga. These fatty acids and phospholipids are an imperative byproduct of alga which used in biofuel production. The production of phospholipi...

journal_title：Journal of bioenergetics and biomembranes

authors： Qari HA,Oves M

更新日期：2020-02-01 00:00:00

abstract：:The role of the adenine nucleotide translocase on Ca2+ homeostasis in mitochondria from brown adipose tissue was examined. It was found that in mitochondria incubated with 50 microM Ca2+, ADP was not needed to retain the cation, but it was required for strengthening the inhibitory effect of cyclosporin on membrane per...

journal_title：Journal of bioenergetics and biomembranes

authors： Chávez E,Moreno-Sánchez R,Torres-Marquez ME,Zazueta C,Bravo C,Rodríquez-Enríquez S,García C,Rodriguez JS,Martinez F

更新日期：1996-02-01 00:00:00

abstract：:Changes in protein and fatty acid compositions of flounder sarcoplasmic reticulum during NADH plus ascorbate-dependent lipid peroxidation in vitro were related to the ability of the sarcoplasmic reticulum to sequester Ca+2. Progressive accumulation of high-molecular-weight protein components occurred concomitantly wit...

journal_title：Journal of bioenergetics and biomembranes

authors： Luo SW,Hultin HO

更新日期：1986-08-01 00:00:00

abstract：:Cytoplasmic organelles with an acidic luminal pH include vacuoles, coated vesicles, lysosomes, the Golgi apparatus, and synaptic vesicles. Acidic compartments are also known outside specialized cells such as osteoclasts. The unique acidic pH is formed by V-ATPase (Vacuolar type ATPase), other ion transporters, and the...

journal_title：Journal of bioenergetics and biomembranes

authors： Sun-Wada GH,Wada Y,Futai M

更新日期：2003-08-01 00:00:00

abstract：:Eukaryotic porins or VDACs are a class of transmembrane proteins mainly localized in the outer mitochondrial membrane, whose function is to allow the diffusion of metabolites between the cytosol and the mitochondrion. In Drosophila melanogaster, as in other organisms, a small family of genes encoding porins has been d...

journal_title：Journal of bioenergetics and biomembranes

authors： Specchia V,Guarino F,Messina A,Bozzetti MP,De Pinto V

更新日期：2008-06-01 00:00:00

abstract：:We report on the influence of dielectric pulse injection on the energy metabolism of yeast cells with a planar interdigitated electrode interface. The energy metabolism was measured via NADH fluorescence. The application of dielectric pulses results in a distinct decrease of the fluorescence, indicating a response of ...

journal_title：Journal of bioenergetics and biomembranes

authors： Reiher A,Warnke C,Radoch S,Witte H,Krtschil A,Mair T,Müller SC,Krost A

更新日期：2006-04-01 00:00:00

abstract：:The oxidation of NADH by mouse liver plasma membranes was shown to be accompanied by the formation of H2O2. The rate of H2O2 formation was less than one-tenth the rate of oxygen uptake and much slower than the rate of reduction of artificial electron acceptors. The optimum pH for this reaction was 7.0 and the Km value...

journal_title：Journal of bioenergetics and biomembranes

authors： Ramasarma T,Swaroop A,MacKellar W,Crane FL

更新日期：1981-12-01 00:00:00

abstract：:The possibility is analyzed that the pH of the water space localized inside the invagination of a membrane can differ from the pH of the external bulk buffer outside the invagination. The proton flow responsible for decreased pH values inside mitochondrial cristae and membrane invaginations of cyanobacteria has been c...

journal_title：Journal of bioenergetics and biomembranes

authors： Kara-Ivanov M

更新日期：1983-06-01 00:00:00

abstract：:The mitochondrial UPR (UPRmt) is rapidly gaining attention. While most studies on the UPRmt have focused on its role in aging, emerging studies suggest an important role of the UPRmt in cancer. Further, several of the players of the UPRmt in mammalian cells have well reported roles in the maintenance of the organelle....

journal_title：Journal of bioenergetics and biomembranes

authors： Kenny TC,Germain D

更新日期：2017-08-01 00:00:00

abstract：:Previous in vitro studies indicated that mutation of both K234 and K236 to arginine, glutamine, or glutamic acid impaired the ability of the voltage-dependent anion channel (VDAC1) to insert into the outer membrane of the mitochondria (Smith et al. 1995). These same mutants were expressed in a strain of Saccharomyces ...

journal_title：Journal of bioenergetics and biomembranes

authors： Angeles R,Devine J,Barton K,Smith M,McCauley R

更新日期：1999-04-01 00:00:00

abstract：:Liver mitochondria isolated from rats 24 h after a single subcutaneous injection of 8 mg thyroxine per kilogram body weight were compared with those isolated from control rats that received injections of isotonic saline at the same time. The mitochondria isolated from the thyroxine-treated rats show higher rates of en...

journal_title：Journal of bioenergetics and biomembranes

authors： Shears SB,Bronk JR

更新日期：1980-12-01 00:00:00

abstract：:As the terminal component of the mitochondrial respiratory chain, cytochrome c oxidase plays a vital role in cellular energy transformation. Human cytochrome c oxidase is composed of 13 subunits. The three major subunits form the catalytic core and are encoded by mitochondrial DNA (mtDNA). The remaining subunits are n...

journal_title：Journal of bioenergetics and biomembranes

authors： Taanman JW

更新日期：1997-04-01 00:00:00

abstract：:The cystic fibrosis transmembrane conductance regulator (CFTR) forms an anion-selective channel involved in epithelial chloride transport. Recent studies have provided new insights into the structural determinants of the channel's functional properties, such as anion selectivity, single-channel conductance, and gating...

journal_title：Journal of bioenergetics and biomembranes

authors： Akabas MH,Cheung M,Guinamard R

更新日期：1997-10-01 00:00:00

abstract：:During fermentation Escherichia coli transport succinate mainly via Dcu family carriers. Current paper describes the role of externally added succinate on N'N'-dicyclohexylcarbodiimide (DCCD) sensitive ATPase activity and H+ flux depending on potassium ions. At pH 7.5 in wild type membrane vesicles DCCD-sensitive ATPa...

journal_title：Journal of bioenergetics and biomembranes

authors： Mikoyan G,Karapetyan L,Vassilian A,Trchounian A,Trchounian K

更新日期：2020-10-01 00:00:00

abstract：:The formation of paracrystalline inclusions in mitochondria following postmortem aging in situ is further investigated. Inclusions are found to localize either in the mitochondrial intracristal space or between the inner and outer membrane. The greater majority of the inclusions are of the intracristal type. pH is not...

journal_title：Journal of bioenergetics and biomembranes

authors： Cheah KS,Cheah AM

更新日期：1977-04-01 00:00:00

abstract：:Yeasts capable of growing and surviving at high temperatures are regarded as thermotolerant. For appropriate functioning of cellular processes and cell survival, the maintenance of an optimal redox state is critical of reducing and oxidizing species. We studied mitochondrial functions of the thermotolerant Kluyveromyc...

journal_title：Journal of bioenergetics and biomembranes

authors： Mejía-Barajas JA,Martínez-Mora JA,Salgado-Garciglia R,Noriega-Cisneros R,Ortiz-Avila O,Cortés-Rojo C,Saavedra-Molina A

更新日期：2017-04-01 00:00:00

abstract：:Mitochondria are dynamic structures for which fusion and fission are well characterized for rapidly dividing cells in culture. Based on these data, it has recently been proposed that high respiratory activity is the result of fusion and formation of mitochondrial reticulum, while fission results in fragmented mitochon...

journal_title：Journal of bioenergetics and biomembranes

authors： Varikmaa M,Guzun R,Grichine A,Gonzalez-Granillo M,Usson Y,Boucher F,Kaambre T,Saks V

更新日期：2013-08-01 00:00:00

abstract：:Hydroxyl radical (HO•) production in photosystem II (PSII) was studied by electron paramagnetic resonance (EPR) spin-trapping technique. It is demonstrated here that the exposure of PSII membranes to heat stress (40 °C) results in HO• formation, as monitored by the formation of EMPO-OH adduct EPR signal. The presence ...

journal_title：Journal of bioenergetics and biomembranes

authors： Yadav DK,Pospíšil P

更新日期：2012-06-01 00:00:00

abstract：:Electron microscopy (EM) in combination with image analysis is a powerful technique to study protein structure at low- and high resolution. Since electron micrographs of biological objects are very noisy, substantial improvement of image quality can be obtained by averaging individual projections. Crystallographic and...

journal_title：Journal of bioenergetics and biomembranes

authors： Boekema EJ,Boonstra AF,Dekker JP,Rögner M

更新日期：1994-02-01 00:00:00

abstract：:The chronology of the major discoveries important in elucidating certain aspects of the molecular basis of transmembrane signaling is briefly reviewed. Recent developments linking cell stimulation and transformation are intimated. ...

journal_title：Journal of bioenergetics and biomembranes

authors： Badwey JA

更新日期：1991-02-01 00:00:00

abstract：:Vicious cycle theories of aging and oxidative stress propose that ROS produced by the mitochondrial electron transport chain damage the mitochondria leading exponentially to more ROS production and mitochondrial damage. Although this theory is widely discussed in the field of research on aging and oxidative stress, th...

journal_title：Journal of bioenergetics and biomembranes

authors： Sanz A,Caro P,Gómez J,Barja G

更新日期：2006-04-01 00:00:00

abstract：:Crude membrane preparations of a rho0 mutant of Saccharomyces cerevisiae exhibit Mg2+-dependent ATPase activity. Over the optimal pH range, 5.0-6.75, the apparent Vmax of the enzyme equals 590 nmoles of ATP hydrolyzed per minute per milligram protein, with an apparent Km for ATP of 1.3 mM. ATP hydrolysis is insensitiv...

journal_title：Journal of bioenergetics and biomembranes

authors： McDonough JP,Jaynes PK,Mahler HR

更新日期：1980-08-01 00:00:00

abstract：:Proton transport-coupled unisite catalysis was measured with the H(+)-ATPase from chloroplasts. The reaction was measured in the ATP hydrolysis direction under deenergized conditions and in the ATP synthesis direction under energized conditions. The equilibrium constant of the enzyme does not change upon energization,...

journal_title：Journal of bioenergetics and biomembranes

authors： Gräber P,Labahn A

更新日期：1992-10-01 00:00:00

abstract：:The molecular mechanism by which the membrane-embedded FO sector of the mitochondrial ATP synthase translocates protons, thus dissipating the transmembrane protonmotive force and leading to ATP synthesis, involves the neutralization of the carboxylate residues of the c-ring. Carboxylates are thought to constitute the ...

journal_title：Journal of bioenergetics and biomembranes

authors： Nesci S,Ventrella V,Trombetti F,Pirini M,Pagliarani A

更新日期：2013-06-01 00:00:00

abstract：:We investigated the effects of K(ATP) channel openers diazoxide and pinacidil on the respiration rate and membrane potential (deltapsi) of rat heart mitochondria, oxidizing pyruvate and malate. Diazoxide and pinacidil (58.8-1348.3 microM) increased the V2 (-ADP) respiration rate accordingly by 13-208% and 30-273% and ...

journal_title：Journal of bioenergetics and biomembranes

authors： Kopustinskiene DM,Jovaisiene J,Liobikas J,Toleikis A

更新日期：2002-02-01 00:00:00

abstract：:Traumatic brain injury (TBI) is still the leading cause of disability in young adults worldwide. The major mechanisms - diffuse axonal injury, cerebral contusion, ischemic neurological damage, and intracranial hematomas have all been shown to be associated with mitochondrial dysfunction in some form. Mitochondrial dys...

journal_title：Journal of bioenergetics and biomembranes

authors： Gajavelli S,Sinha VK,Mazzeo AT,Spurlock MS,Lee SW,Ahmed AI,Yokobori S,Bullock RM

更新日期：2015-04-01 00:00:00

abstract：:At present there is a poor understanding of the events that lead up to neuronal apoptosis that occurs in neurodegenerative diseases and following acute ischemic episodes. Apoptosis is critical for the elimination of unwanted neurons within the developing nervous system. The Bcl-2 family of proteins contains pro- and a...

journal_title：Journal of bioenergetics and biomembranes

authors： Ward MW,Kögel D,Prehn JH

更新日期：2004-08-01 00:00:00

abstract：:A series of amphiphilic polymethlyenecarboxymaleimides has been synthesized for use as sulfhydryl reagents applicable to membrane proteins. Physical properties of the compounds which are relevant to their proposed mode of action have been determined. By comparing rates of reaction in aqueous and aprotic solvents, the ...

journal_title：Journal of bioenergetics and biomembranes

authors： Griffiths DG,Partis MD,Churchill P,Brenner SC,Fleischer S,Moore RJ,Beechey RB

更新日期：1990-10-01 00:00:00

abstract：:Proteins specifically involved in the biogenesis of respiratory complex I in eukaryotes have been characterized. The complex I intermediate associated proteins CIA30 and CIA84 are tightly bound to an assembly intermediate of the membrane arm. Like chaperones, they are involved in multiple rounds of membrane arm assemb...

journal_title：Journal of bioenergetics and biomembranes

authors： Schulte U

更新日期：2001-06-01 00:00:00

abstract：:The Mg2+ dependent asymmetry of the F(1)-ATPase catalytic sites leads to the differences in affinity for nucleotides and is an essential component of the binding-change mechanism. Changes in metal ligands during the catalytic cycle responsible for this asymmetry were characterized by vanadyl (V(IV) + O)2+, a functiona...

journal_title：Journal of bioenergetics and biomembranes

authors： Frasch WD

更新日期：2000-10-01 00:00:00