Modulation of matrix Ca2+ content by the ADP/ATP carrier in brown adipose tissue mitochondria. Influence of membrane lipid composition.

Abstract:

:The role of the adenine nucleotide translocase on Ca2+ homeostasis in mitochondria from brown adipose tissue was examined. It was found that in mitochondria incubated with 50 microM Ca2+, ADP was not needed to retain the cation, but it was required for strengthening the inhibitory effect of cyclosporin on membrane permeability transition as induced by menadione. In addition, carboxyatractyloside was unable to promote matrix Ca2+ release, even though it inhibits the ADP exchange reaction. However, when the Ca2+ concentration was increased to 150 microM carboxyatractyloside did induce Ca2+ release, and ADP favored Ca2+ retention. Determination of cardiolipin content in the inner membrane vesicles showed a greater concentration in brown adipose tissue mitochondria than that found in kidney mitochondria. It suggested that the failure of the adenine nucleotide translocase to influence membrane permeability transition depends on the lipid composition of the inner membrane.

journal_name

J Bioenerg Biomembr

authors

Chávez E,Moreno-Sánchez R,Torres-Marquez ME,Zazueta C,Bravo C,Rodríquez-Enríquez S,García C,Rodriguez JS,Martinez F

subject

Has Abstract

pub_date

1996-02-01 00:00:00

pages

69-76

issue

1

eissn

0145-479X

issn

1573-6881

journal_volume

28

pub_type

杂志文章
  • Correction to: The synergistic effect of mefenamic acid with ionizing radiation in colon cancer.

    abstract::The original version of this article unfortunately contained a mistake. The name of "Zohreh Noaparast" is now corrected in the author group of this article. ...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 已发布勘误

    doi:10.1007/s10863-019-09803-w

    authors: Hosseinimehr SJ,Safavi Z,Farahani SK,Noaparast Z,Ghasemi A,Asgarian-Omran H

    更新日期:2019-08-01 00:00:00

  • Transport of vitamin C in animal and human cells.

    abstract::The transport systems of animal and human tissues for vitamin C are reviewed with respect to their properties. It emerges that pure diffusion plays only a very minor role while a variety of more or less specific transporters is found on cellular membranes. Although most tissues prefer the reduced ascorbate over the ox...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章,评审

    doi:10.1007/BF00762776

    authors: Goldenberg H,Schweinzer E

    更新日期:1994-08-01 00:00:00

  • Cytochrome c oxidase of Euglena gracilis: purification, characterization, and identification of mitochondrially synthesized subunits.

    abstract::Cytochrome c oxidase was purified from mitochondria of Euglena gracilis and separated into 15 different polypeptide subunits by polyacrylamide gel electrophoresis. All 15 subunits copurify through various purification procedures, and the subunit composition of the isolated enzyme is identical to that of the immunoprec...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/BF00762727

    authors: Brönstrup U,Hachtel W

    更新日期:1989-06-01 00:00:00

  • Introduction to the mini-review series on mitochondrial matters in epilepsy.

    abstract::Dysfunction of neuronal metabolism is central to all forms of seizure activity. Clinical, genetic and metabolic studies have implicated mitochondria in the process. Alterations in electron transport, generation of reactive oxygen species, calcium metabolism and apoptosis all have been described in human and animal ner...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type:

    doi:10.1007/s10863-010-9322-7

    authors: Sack GH Jr

    更新日期:2010-12-01 00:00:00

  • The Na+ cycle of extreme alkalophiles: a secondary Na+/H+ antiporter and Na+/solute symporters.

    abstract::Extremely alkalophilic bacteria that grow optimally at pH 10.5 and above are generally aerobic bacilli that grow at mesophilic temperatures and moderate salt levels. The adaptations to alkalophily in these organisms may be distinguished from responses to combined challenges of high pH together with other stresses such...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章,评审

    doi:10.1007/BF00762685

    authors: Krulwich TA,Guffanti AA

    更新日期:1989-12-01 00:00:00

  • TIPE2 suppresses progression and tumorigenesis of the oral tongue squamous cell carcinoma by regulating FoxP3+ regulatory T cells.

    abstract::To discover the effect of tumor necrosis factor-alpha-induced protein 8-like 2 (TIPE2) on the oral tongue squamous cell carcinoma (OTSCC) via affecting FoxP3+ regulatory T (Treg) cells. Immunohistochemistry was conducted to examine TIPE2 and FoxP3 expressions in OTSCC tumor tissues and corresponding oral mucosa. Tca81...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/s10863-020-09840-w

    authors: Zhao LL

    更新日期:2020-08-01 00:00:00

  • The mitochondrial inner membrane anion channel is inhibited by DIDS.

    abstract::The mitochondrial inner membrane anion channel (IMAC) is a channel, identified by flux studies in intact mitochondria, which has a broad anion selectivity and is maintained closed or inactive by matrix Mg2+ and H+. We now present evidence that this channel, like many other chloride/anion channels, is reversibly blocke...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/BF02110652

    authors: Beavis AD,Davatol-Hag H

    更新日期:1996-04-01 00:00:00

  • The structure and biochemistry of the vacuolar H+ ATPase in proximal and distal urinary acidification.

    abstract::Vacuolar H+ ATPases participate in renal hydrogen ion secretion in both the proximal and distal nephron. These plasma membrane forms of the vacuolar H+ ATPase are regulated physiologically to maintain the acid-base balance of the organism. Proton transporting renal cells have requirements for constitutive acidificatio...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章,评审

    doi:10.1007/BF00762528

    authors: Gluck SL

    更新日期:1992-08-01 00:00:00

  • Lipid composition and fluidity of liver plasma membranes from rats with chronic dietary iron overload.

    abstract::Liver plasma membranes isolated from rats with chronic dietary iron overload showed a large modification of their phospholipid fatty acid composition. Specifically, a significant decrease in polyunsaturated fatty acids and a parallel increase in saturated fatty acids was observed. This pattern was consistent with the ...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/BF00762524

    authors: Pietrangelo A,Tripodi A,Carulli N,Tomasi A,Ceccarelli D,Ventura E,Masini A

    更新日期:1989-08-01 00:00:00

  • External succinate and potassium ions influence Dcu dependent FOF1-ATPase activity and H+ flux of Escherichia coli at different pHs.

    abstract::During fermentation Escherichia coli transport succinate mainly via Dcu family carriers. Current paper describes the role of externally added succinate on N'N'-dicyclohexylcarbodiimide (DCCD) sensitive ATPase activity and H+ flux depending on potassium ions. At pH 7.5 in wild type membrane vesicles DCCD-sensitive ATPa...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/s10863-020-09847-3

    authors: Mikoyan G,Karapetyan L,Vassilian A,Trchounian A,Trchounian K

    更新日期:2020-10-01 00:00:00

  • Models of localized energy coupling.

    abstract::It is proven that any model of localized protonmotive energy coupling that relies upon properties of a homogeneous surface phase must, when operated in the steady state, lead to bulk phase electrochemical potentials for protons that are as large as those required by the delocalized chemiosmotic theory. To obtain model...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章,评审

    doi:10.1007/BF00743612

    authors: Nagle JF,Dilley RA

    更新日期:1986-02-01 00:00:00

  • Kinetics of light emission and oxygen consumption by bioluminescent bacteria.

    abstract::Oxygen plays a key role in bacterial bioluminescence. The simultaneous and continuous kinetics of oxygen consumption and light emission during a complete exhaustion of the exogenous oxygen present in a closed system has been investigated. The kinetics are performed with Vibrio fischeri, V. harveyi, and Photobacterium ...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1023/a:1010615508916

    authors: Bourgois JJ,Sluse FE,Baguet F,Mallefet J

    更新日期:2001-08-01 00:00:00

  • Neutral magnesium-dependent sphingomyelinase from liver plasma membrane: purification and inhibition by ubiquinol.

    abstract::Plasma membranes isolated from pig liver contained almost no acid sphingomyelinase but significant neutral magnesium-dependent sphingomyelinase that was activated by phosphatidylserine. We report here the purification to apparent homogeneity of neutral sphingomyelinase of about 87 kDa from liver plasma membranes. The ...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1023/a:1010704715979

    authors: Martín SF,Navarro F,Forthoffer N,Navas P,Villalba JM

    更新日期:2001-04-01 00:00:00

  • Drug-stimulated ATPase activity of the human P-glycoprotein.

    abstract::The human multidrug resistance protein, or P-glycoprotein (Pgp), exhibits a high-capacity drug-dependent ATP hydrolytic activity that is a direct reflection of its drug transport capability. This activity is readily measured in membranes isolated from cultured insect cells infected with a baculovirus carrying the huma...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章,评审

    doi:10.1007/BF02110329

    authors: Scarborough GA

    更新日期:1995-02-01 00:00:00

  • Mitochondrial complex I inhibitors, acetogenins, induce HepG2 cell death through the induction of the complete apoptotic mitochondrial pathway.

    abstract::The development of new anti-neoplastic drugs is a key issue for cancer chemotherapy due to the reality that, most likely, certain cancer cells are resistant to current chemotherapy. The past two decades have witnessed tremendous advances in our understanding of the pathogenesis of cancer. These advances have allowed i...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/s10863-012-9489-1

    authors: de Pedro N,Cautain B,Melguizo A,Vicente F,Genilloud O,Peláez F,Tormo JR

    更新日期:2013-02-01 00:00:00

  • Matters of the heart in bioenergetics: mitochondrial fusion into continuous reticulum is not needed for maximal respiratory activity.

    abstract::Mitochondria are dynamic structures for which fusion and fission are well characterized for rapidly dividing cells in culture. Based on these data, it has recently been proposed that high respiratory activity is the result of fusion and formation of mitochondrial reticulum, while fission results in fragmented mitochon...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章,评审

    doi:10.1007/s10863-012-9494-4

    authors: Varikmaa M,Guzun R,Grichine A,Gonzalez-Granillo M,Usson Y,Boucher F,Kaambre T,Saks V

    更新日期:2013-08-01 00:00:00

  • The potential role of mitochondrial dysfunction in seizure-associated cell death in the hippocampus and epileptogenesis.

    abstract::Epilepsy is considered one of the most common neurological disorders worldwide. The burst firing neurons associated with prolonged epileptic discharges could lead to a large number of changes with events of cascades at the cellular level. From its role as the cellular powerhouse, mitochondria also play a crucial role ...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章,评审

    doi:10.1007/s10863-010-9321-8

    authors: Chen SD,Chang AY,Chuang YC

    更新日期:2010-12-01 00:00:00

  • Energetics of isolated hepatocyte swelling induced by sodium co-transported amino acids.

    abstract::This study was designed to investigate the energetics of isolated rat hepatocyte swelling due to sodium-cotransported amino acid accumulation in a medium containing either glucose or octanoate as basal substrate. We show that the size of the increase in cytosolic volume is directly correlated with the total amino acid...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1023/a:1022487119390

    authors: Espié P,Devin A,Guérin B,Rigoulet M

    更新日期:1997-12-01 00:00:00

  • 17-Demethoxy-reblastatin, an Hsp90 inhibitor, induces mitochondria-mediated apoptosis through downregulation of Mcl-1 in human hepatocellular carcinoma cells.

    abstract::Heat shock protein 90 (Hsp90) is an attractive therapeutic target. Geldanamycin (GA), the first identified Hsp90 inhibitor, exhibited potent antitumor activity, but possessed significant hepatotoxicity. To overcome the hepatotoxicity derived from the quinone structure of GA, a non-quinone GA derivative 17-demethoxy-re...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/s10863-015-9620-1

    authors: Zhao S,Li H,Jiang C,Ma T,Wu C,Huo Q,Liu H

    更新日期:2015-10-01 00:00:00

  • Coordinated decrease of the expression of the mitochondrial and nuclear complex I genes in a mitochondrial mutant of Drosophila.

    abstract::We have studied a mutant strain of Drosophila in which 80% of the mitochondrial DNA molecules have lost over 30% of their coding region through deletion. This deletion affects genes encoding five subunits of complex I of the respiratory chain (NADH:ubiquinone oxidoreductase). The enzymatic activity of complex I in the...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1023/b:jobb.0000023624.06665.40

    authors: Farge G,Touraille S,Lachaume P,Debise R,Procaccio V,Alziari S

    更新日期:2004-04-01 00:00:00

  • Stimulation of electron transport from photosystem II to photosystem I in spinach chloroplasts.

    abstract::Electron transport from Photosystem II to Photosystem I of spinach chloroplasts can be stimulated by bicarbonate and various carbonyl or carboxyl compounds. Monovalent or divalent cations, which have hitherto been implicated in the energy distribution between the two photosystems, i.e., "spillover" phenomena at low li...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/BF00744683

    authors: Barr R,Melhem R,Lezotte AL,Crane FL

    更新日期:1980-08-01 00:00:00

  • The energy-conserving and energy-dissipating processes in mitochondria isolated from wild type and nonripening tomato fruits during development on the plant.

    abstract::Bioenergetics of tomato (Lycopersicon esculentum) development on the plant was followed from the early growing stage to senescence in wild type (climacteric) and nonripening mutant (nor, non-climacteric) fruits. Fruit development was expressed in terms of evolution of chlorophyll a content allowing the assessment of a...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1023/a:1022574327117

    authors: Almeida AM,Navet R,Jarmuszkiewicz W,Vercesi AE,Sluse-Goffart CM,Sluse FE

    更新日期:2002-12-01 00:00:00

  • Cloning and sequencing of V-ATPase subunit d from mung bean and its function in passive proton transport.

    abstract::We have previously shown that vacuolar H+-ATPase subcomplex V(o) from mung bean contains subunit d, however, its sequence and function were unknown. In the present study, we report the cloning and recombinant over expression of subunit d from mung bean in E. coli. To study the function of subunit d, two vacuolar H+-AT...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/s10863-008-9193-3

    authors: Ouyang Z,Li Z,Zhang X

    更新日期:2008-12-01 00:00:00

  • Energy transduction and transport processes in thermophilic bacteria.

    abstract::Bacterial growth at the extremes of temperature has remained a fascinating aspect in the study of membrane function and structure. The stability of the integral membrane proteins of thermophiles make them particularly amenable to study. Respiratory enzymes of thermophiles appear to be functionally similar to the mesop...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章,评审

    doi:10.1007/BF00762352

    authors: Konings WN,Tolner B,Speelmans G,Elferink MG,de Wit JG,Driessen AJ

    更新日期:1992-12-01 00:00:00

  • Neural plasticity in developing and adult olfactory pathways - focus on the human olfactory bulb.

    abstract::The topic of human adult neural plasticity and neurogenesis is of great interest for medical and scientific community, but it is also largely debated. In the last years, an increasing interest has been paid to the olfactory system, and particularly to the plasticity of the olfactory bulb (OB). While the molecular/cell...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章,评审

    doi:10.1007/s10863-018-9780-x

    authors: Huart C,Rombaux P,Hummel T

    更新日期:2019-02-01 00:00:00

  • Characterization of cytochrome oxidase purified from rat liver.

    abstract::The purpose of this study was to characterize the physical properties of cytochrome c oxidase from rat liver. The enzyme was extracted from isolated mitochondria with nonionic detergents and further purified by ion-exchange chromatography on DEAE Bio-Gel A. The purified enzyme contained 9.64 nmol heme a/mg protein and...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/BF00743154

    authors: Ades IZ,Cascarano J

    更新日期:1977-08-01 00:00:00

  • Evaluation by steady-state enzyme kinetics of the role of tightly bound nucleotides during photophosphorylation.

    abstract::The ATP synthetase of chloroplast membranes binds ADP and ATP with high affinity, and the binding becomes quasi-irreversible under certain conditions. One explanation of the function of these nucleotides is that they are transiently tightly bound during ATP synthesis as part of the catalytic process, and that the rele...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/BF00744524

    authors: Tiefert MA,Shavit N

    更新日期:1983-10-01 00:00:00

  • Notch pathway activation mediated the senescence of endothelial progenitor cells in hypercholesterolemic mice.

    abstract::Hyperlipidemia is an important factor in the induction of cardiovascular diseases. However, the molecular mechanisms underlying the vascular injury involved in hyperlipidemia remains unclear. This study aimed to investigate the Notch pathway of endothelial progenitor cells (EPCs) in reendothelialization after vascular...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/s10863-020-09853-5

    authors: Liang J,Ke X,Yang R,Wang X,Du Z,Hu C

    更新日期:2020-12-01 00:00:00

  • Unimolecular study of the interaction between the outer membrane protein OmpF from E. coli and an analogue of the HP(2-20) antimicrobial peptide.

    abstract::Little is known on antimicrobial peptide permeation through outer membrane channels in gram-negative bacteria. Herein, we probed at a single-molecule level the interaction of two different peptides, magainin 2 and HPA3P with OmpF from E. coli. HPA3P is an analogue of the antimicrobial peptide HP(2-20) isolated from th...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/s10863-010-9273-z

    authors: Apetrei A,Asandei A,Park Y,Hahm KS,Winterhalter M,Luchian T

    更新日期:2010-04-01 00:00:00

  • On the correlation between the activity of ATP-hydrolase and the kinetics of the flash-induced P515 electrochromic bandshift in spinach chloroplasts.

    abstract::The P515 absorbance change upon single-turnover light flashes has been studied in intact leaves and isolated chloroplasts from spinach. A comparative study of the effects of preillumination on the kinetics of the P515 response and on the activity of the chloroplast ATPase has been made. The slow component (reaction 2)...

    journal_title:Journal of bioenergetics and biomembranes

    pub_type: 杂志文章

    doi:10.1007/BF00751054

    authors: Peters RL,Bossen M,van Kooten O,Vredenberg WJ

    更新日期:1983-12-01 00:00:00