The potential role of mitochondrial dysfunction in seizure-associated cell death in the hippocampus and epileptogenesis.

abstract：:Evidence suggests membrane bound F(1)F(0)-ATPase complexes form stable associations such that dimers can be retrieved from detergent lysates of mitochondria isolated from a range of sources including algae, higher plants, yeast and bovine heart, and plant chloroplasts. The physiological relevance of these interactions...

journal_title：Journal of bioenergetics and biomembranes

authors： Gavin PD,Prescott M,Devenish RJ

更新日期：2005-04-01 00:00:00

abstract：:Bioenergetics of tomato (Lycopersicon esculentum) development on the plant was followed from the early growing stage to senescence in wild type (climacteric) and nonripening mutant (nor, non-climacteric) fruits. Fruit development was expressed in terms of evolution of chlorophyll a content allowing the assessment of a...

journal_title：Journal of bioenergetics and biomembranes

authors： Almeida AM,Navet R,Jarmuszkiewicz W,Vercesi AE,Sluse-Goffart CM,Sluse FE

更新日期：2002-12-01 00:00:00

abstract：:Gap junction channels have long been viewed as static structures containing a large-diameter, aqueous pore. This pore has a high permeability to hydrophilic molecules of approximately 900 daltons in molecular weight and a weak ionic selectivity. The evidence leading to these conclusions is reviewed in the context of m...

journal_title：Journal of bioenergetics and biomembranes

authors： Veenstra RD

更新日期：1996-08-01 00:00:00

abstract：:Vacuolar H+ ATPases participate in renal hydrogen ion secretion in both the proximal and distal nephron. These plasma membrane forms of the vacuolar H+ ATPase are regulated physiologically to maintain the acid-base balance of the organism. Proton transporting renal cells have requirements for constitutive acidificatio...

journal_title：Journal of bioenergetics and biomembranes

authors： Gluck SL

更新日期：1992-08-01 00:00:00

abstract：:Changes in protein and fatty acid compositions of flounder sarcoplasmic reticulum during NADH plus ascorbate-dependent lipid peroxidation in vitro were related to the ability of the sarcoplasmic reticulum to sequester Ca+2. Progressive accumulation of high-molecular-weight protein components occurred concomitantly wit...

journal_title：Journal of bioenergetics and biomembranes

authors： Luo SW,Hultin HO

更新日期：1986-08-01 00:00:00

abstract：:The plasma membrane-enriched fraction isolated from smooth muscle of rat gastric fundus was found to contain a substantial level of potassium-stimulated p-nitrophenylphosphatase activity (K-pNPPase), and its subcellular distribution closely resembled that of other plasma membrane enzyme markers. The kinetic profile of...

journal_title：Journal of bioenergetics and biomembranes

authors： Kostka P,Kwan CY

更新日期：1986-08-01 00:00:00

abstract：:The total amount of cellular mitochondrial DNA (mtDNA) varies widely and seems to be related to the nature and metabolic state of tissues and cells in culture. It is not known, however, whether this variation has any significance in vivo, and to which extent it regulates energy production. To better understand the imp...

journal_title：Journal of bioenergetics and biomembranes

authors： Rocher C,Taanman JW,Pierron D,Faustin B,Benard G,Rossignol R,Malgat M,Pedespan L,Letellier T

更新日期：2008-04-01 00:00:00

abstract：:Both cellular proliferation and apoptosis (programmed cell death) have been claimed to be modulated, perhaps even triggered by, changes in intracellular pH. In this review, we summarize the evidence that gave rise to these hypotheses. To facilitate a critical appraisal of the existing data, we briefly review the main ...

journal_title：Journal of bioenergetics and biomembranes

authors： Shrode LD,Tapper H,Grinstein S

更新日期：1997-08-01 00:00:00

abstract：:The 8-kDa subunit c of the E. coli F0 ATP-synthase proton channel was tested for Ca++ binding activity using a 45Ca++ ligand blot assay after transferring the protein from SDS-PAGE gels onto polyvinyl difluoride membranes. The purified subunit c binds 45Ca++ strongly with Ca++ binding properties very similar to those ...

journal_title：Journal of bioenergetics and biomembranes

authors： Zakharov SD,Li X,Red'ko TP,Dilley RA

更新日期：1996-12-01 00:00:00

abstract：:Electron transport from Photosystem II to Photosystem I of spinach chloroplasts can be stimulated by bicarbonate and various carbonyl or carboxyl compounds. Monovalent or divalent cations, which have hitherto been implicated in the energy distribution between the two photosystems, i.e., "spillover" phenomena at low li...

journal_title：Journal of bioenergetics and biomembranes

authors： Barr R,Melhem R,Lezotte AL,Crane FL

更新日期：1980-08-01 00:00:00

abstract：:The cystic fibrosis transmembrane conductance regulator (CFTR) forms an anion-selective channel involved in epithelial chloride transport. Recent studies have provided new insights into the structural determinants of the channel's functional properties, such as anion selectivity, single-channel conductance, and gating...

journal_title：Journal of bioenergetics and biomembranes

authors： Akabas MH,Cheung M,Guinamard R

更新日期：1997-10-01 00:00:00

abstract：:The organization of the oxidative phosphorylation (OXPHOS) system within the inner mitochondrial membrane appears to be far more complicated than previously thought. In particular, the individual protein complexes of the OXPHOS system (complexes I to V) were found to specifically interact forming defined supramolecula...

journal_title：Journal of bioenergetics and biomembranes

authors： Dudkina NV,Sunderhaus S,Boekema EJ,Braun HP

更新日期：2008-10-01 00:00:00

abstract：:ATP1-111, a suppressor of the slow-growth phenotype of yme1Delta lacking mitochondrial DNA is due to the substitution of phenylalanine for valine at position 111 of the alpha-subunit of mitochondrial ATP synthase (Atp1p in yeast). The suppressing activity of ATP1-111 requires intact beta (Atp2p) and gamma (Atp3p) subu...

journal_title：Journal of bioenergetics and biomembranes

authors： Francis BR,White KH,Thorsness PE

更新日期：2007-04-01 00:00:00

abstract：:The inner membrane of yeast and mammalian mitochondria has been studied in situ with a patch clamp electrode. Anion channels were found in both cases, although their behavior and regulation are different. In mammalian mitochondria, the principal channel is of around 100 pS conductance and opens mainly under depolarize...

journal_title：Journal of bioenergetics and biomembranes

authors： Ballarin C,Sorgato MC

更新日期：1996-04-01 00:00:00

abstract：:The presence of transplasma membrane electron transport in a variety of plant cells and tissues is reported. It is now agreed that this property of eukaryotic cells is of ubiquitous nature. Studies with highly purified plasma membranes have established the presence of electron transport enzymes. Two types of activitie...

journal_title：Journal of bioenergetics and biomembranes

authors： Misra PC

更新日期：1991-06-01 00:00:00

abstract：:Dysfunction of neuronal metabolism is central to all forms of seizure activity. Clinical, genetic and metabolic studies have implicated mitochondria in the process. Alterations in electron transport, generation of reactive oxygen species, calcium metabolism and apoptosis all have been described in human and animal ner...

journal_title：Journal of bioenergetics and biomembranes

authors： Sack GH Jr

更新日期：2010-12-01 00:00:00

abstract：:We investigated the effects of K(ATP) channel openers diazoxide and pinacidil on the respiration rate and membrane potential (deltapsi) of rat heart mitochondria, oxidizing pyruvate and malate. Diazoxide and pinacidil (58.8-1348.3 microM) increased the V2 (-ADP) respiration rate accordingly by 13-208% and 30-273% and ...

journal_title：Journal of bioenergetics and biomembranes

authors： Kopustinskiene DM,Jovaisiene J,Liobikas J,Toleikis A

更新日期：2002-02-01 00:00:00

abstract：:The human multidrug resistance protein, or P-glycoprotein (Pgp), exhibits a high-capacity drug-dependent ATP hydrolytic activity that is a direct reflection of its drug transport capability. This activity is readily measured in membranes isolated from cultured insect cells infected with a baculovirus carrying the huma...

journal_title：Journal of bioenergetics and biomembranes

authors： Scarborough GA

更新日期：1995-02-01 00:00:00

abstract：:Research on VDAC has accelerated as evidence grows of its importance in mitochondrial function and in apoptosis. New investigators entering the field are often confounded by the VDAC literature and its many apparent conflicts and contradictions. This review is an effort to shed light on the situation and identify reli...

journal_title：Journal of bioenergetics and biomembranes

authors： Rostovtseva TK,Tan W,Colombini M

更新日期：2005-06-01 00:00:00

abstract：:In the present study we have observed a higher state of coupling in respiring mitochondria isolated from green as compared to red tomatoes (Lycopersicon esculentum, Mill.). Green tomato mitochondria produced a membrane potential (deltapsi) high enough to phosphorylate ADP, whereas in red tomato mitochondria, BSA and A...

journal_title：Journal of bioenergetics and biomembranes

authors： Costa AD,Nantes IL,Jezek P,Leite A,Arruda P,Vercesi AE

更新日期：1999-10-01 00:00:00

abstract：:The P515 absorbance change upon single-turnover light flashes has been studied in intact leaves and isolated chloroplasts from spinach. A comparative study of the effects of preillumination on the kinetics of the P515 response and on the activity of the chloroplast ATPase has been made. The slow component (reaction 2)...

journal_title：Journal of bioenergetics and biomembranes

authors： Peters RL,Bossen M,van Kooten O,Vredenberg WJ

更新日期：1983-12-01 00:00:00

abstract：:The proton/hydroxide (H+/OH-) permeability of phospholipid bilayer membranes at neutral pH is at least five orders of magnitude higher than the alkali or halide ion permeability, but the mechanism(s) of H+/OH- transport are unknown. This review describes the characteristics of H+/OH- permeability and conductance throu...

journal_title：Journal of bioenergetics and biomembranes

authors： Gutknecht J

更新日期：1987-10-01 00:00:00

abstract：:The importance of crucial nutrient factors like Phosphate (P) and their limited availability leads to variable fluctuations in fatty acid and phospholipid synthesis in the green alga. These fatty acids and phospholipids are an imperative byproduct of alga which used in biofuel production. The production of phospholipi...

journal_title：Journal of bioenergetics and biomembranes

authors： Qari HA,Oves M

更新日期：2020-02-01 00:00:00

abstract：:The topic of human adult neural plasticity and neurogenesis is of great interest for medical and scientific community, but it is also largely debated. In the last years, an increasing interest has been paid to the olfactory system, and particularly to the plasticity of the olfactory bulb (OB). While the molecular/cell...

journal_title：Journal of bioenergetics and biomembranes

authors： Huart C,Rombaux P,Hummel T

更新日期：2019-02-01 00:00:00

abstract：:Liver plasma membranes isolated from rats with chronic dietary iron overload showed a large modification of their phospholipid fatty acid composition. Specifically, a significant decrease in polyunsaturated fatty acids and a parallel increase in saturated fatty acids was observed. This pattern was consistent with the ...

journal_title：Journal of bioenergetics and biomembranes

authors： Pietrangelo A,Tripodi A,Carulli N,Tomasi A,Ceccarelli D,Ventura E,Masini A

更新日期：1989-08-01 00:00:00

abstract：:Plasma membrane vesicles of HeLa cells are characterized by a drug-responsive oxidation of NADH. The NADH oxidation takes place in an argon or nitrogen atmosphere and in samples purged of oxygen. Direct assay of protein thiols by reaction with 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB; Ellman's reagent), suggests tha...

journal_title：Journal of bioenergetics and biomembranes

authors： Morré DJ,Chueh PJ,Lawler J,Morré DM

更新日期：1998-10-01 00:00:00

abstract：:Many oxidoreductases are constructed from (a) local sites of strongly coupled substrate-redox cofactor partners participating in exchange of electron pairs, (b) electron pair/single electron transducing redox centers, and (c) nonadiabatic, long-distance, single-electron tunneling between weakly coupled redox centers. ...

journal_title：Journal of bioenergetics and biomembranes

authors： Moser CC,Page CC,Farid R,Dutton PL

更新日期：1995-06-01 00:00:00

abstract：:Proton transport-coupled unisite catalysis was measured with the H(+)-ATPase from chloroplasts. The reaction was measured in the ATP hydrolysis direction under deenergized conditions and in the ATP synthesis direction under energized conditions. The equilibrium constant of the enzyme does not change upon energization,...

journal_title：Journal of bioenergetics and biomembranes

authors： Gräber P,Labahn A

更新日期：1992-10-01 00:00:00

abstract：:Affinity labeling and genetic studies on the glycine-rich sequence of the beta subunit of E. coli F-type ATPase are discussed. A model of the structure of the enzyme near the gamma phosphate moiety is proposed. ...

journal_title：Journal of bioenergetics and biomembranes

authors： Futai M,Iwamoto A,Omote H,Maeda M

更新日期：1992-10-01 00:00:00

abstract：:This study was designed to investigate the energetics of isolated rat hepatocyte swelling due to sodium-cotransported amino acid accumulation in a medium containing either glucose or octanoate as basal substrate. We show that the size of the increase in cytosolic volume is directly correlated with the total amino acid...

journal_title：Journal of bioenergetics and biomembranes

authors： Espié P,Devin A,Guérin B,Rigoulet M

更新日期：1997-12-01 00:00:00