abstract：:Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (LHPP) has been recently identified as a novel inhibitor of multiple tumors; however, its role in glioblastoma (GBM) has not been investigated. This study aimed to evaluate whether LHPP exerts a potential tumor-inhibiting role in GBM. Compared with tha...

journal_title：Journal of bioenergetics and biomembranes

authors： Li C,Yang J,Wang W,Li R

更新日期：2021-02-01 00:00:00

abstract：:Hyperlipidemia is an important factor in the induction of cardiovascular diseases. However, the molecular mechanisms underlying the vascular injury involved in hyperlipidemia remains unclear. This study aimed to investigate the Notch pathway of endothelial progenitor cells (EPCs) in reendothelialization after vascular...

journal_title：Journal of bioenergetics and biomembranes

authors： Liang J,Ke X,Yang R,Wang X,Du Z,Hu C

更新日期：2020-12-01 00:00:00

abstract：:Forkhead box protein O6 (FOXO6) has been recently identified as a novel regulator of oxidative stress in multiple pathological processes. However, whether FOXO6 participates in the regulation of oxidative stress of myocardial infarction is unclear. The present study was performed to evaluate the potential role of FOXO...

journal_title：Journal of bioenergetics and biomembranes

authors： Jin A,Zhang Q,Li S,Li B

更新日期：2020-12-01 00:00:00

abstract：:During fermentation Escherichia coli transport succinate mainly via Dcu family carriers. Current paper describes the role of externally added succinate on N'N'-dicyclohexylcarbodiimide (DCCD) sensitive ATPase activity and H+ flux depending on potassium ions. At pH 7.5 in wild type membrane vesicles DCCD-sensitive ATPa...

journal_title：Journal of bioenergetics and biomembranes

authors： Mikoyan G,Karapetyan L,Vassilian A,Trchounian A,Trchounian K

更新日期：2020-10-01 00:00:00

abstract：:Caloric restriction (CR) is widely known to increase life span and resistance to different types of injuries in several organisms. We have previously shown that mitochondria from livers or brains of CR animals exhibit higher calcium uptake rates and lower sensitivity to calcium-induced mitochondrial permeability trans...

journal_title：Journal of bioenergetics and biomembranes

authors： Serna JDC,Caldeira da Silva CC,Kowaltowski AJ

更新日期：2020-08-01 00:00:00

abstract：:To discover the effect of tumor necrosis factor-alpha-induced protein 8-like 2 (TIPE2) on the oral tongue squamous cell carcinoma (OTSCC) via affecting FoxP3+ regulatory T (Treg) cells. Immunohistochemistry was conducted to examine TIPE2 and FoxP3 expressions in OTSCC tumor tissues and corresponding oral mucosa. Tca81...

journal_title：Journal of bioenergetics and biomembranes

authors： Zhao LL

更新日期：2020-08-01 00:00:00

abstract：:The importance of crucial nutrient factors like Phosphate (P) and their limited availability leads to variable fluctuations in fatty acid and phospholipid synthesis in the green alga. These fatty acids and phospholipids are an imperative byproduct of alga which used in biofuel production. The production of phospholipi...

journal_title：Journal of bioenergetics and biomembranes

authors： Qari HA,Oves M

更新日期：2020-02-01 00:00:00

abstract：:The original version of this article unfortunately contained a mistake. The name of "Zohreh Noaparast" is now corrected in the author group of this article. ...

journal_title：Journal of bioenergetics and biomembranes

authors： Hosseinimehr SJ,Safavi Z,Farahani SK,Noaparast Z,Ghasemi A,Asgarian-Omran H

更新日期：2019-08-01 00:00:00

abstract：:Direct and indirect evidences show that elevated glucose concentrations in airway surface liquid (ASL) promote lung infection by pathogens, playing a role in the progression of the Cystic Fibrosis (CF) disease. The joint action of transporter/s for glucose and of the cellular enzymes is essential in order to try to lo...

journal_title：Journal of bioenergetics and biomembranes

authors： Favia M,de Bari L,Lassandro R,Atlante A

更新日期：2019-06-01 00:00:00

abstract：:The topic of human adult neural plasticity and neurogenesis is of great interest for medical and scientific community, but it is also largely debated. In the last years, an increasing interest has been paid to the olfactory system, and particularly to the plasticity of the olfactory bulb (OB). While the molecular/cell...

journal_title：Journal of bioenergetics and biomembranes

authors： Huart C,Rombaux P,Hummel T

更新日期：2019-02-01 00:00:00

abstract：:Human mast cell tryptase has been shown as an activating enzyme in matrix degradation process. The previous study suggest that tryptase either alone or in joining with activation of metalloproteinases, can associate in extra cellular matrix damage and the possible destruction of the basement membrane resulting in phot...

journal_title：Journal of bioenergetics and biomembranes

authors： Wongrattanakamon P,Ampasavate C,Sirithunyalug B,Jiranusornkul S

更新日期：2018-12-01 00:00:00

abstract：:Thylakoids are highly protein-enriched membranes that harbor a number of multicomponent photosynthetic complexes. Similarly to other biological membranes the protein constituents are heterogeneously distributed laterally in the plane of the membrane, however the specific segregation into stacked (grana patches) and un...

journal_title：Journal of bioenergetics and biomembranes

authors： Petrova N,Todinova S,Paunov M,Kovács L,Taneva S,Krumova S

更新日期：2018-12-01 00:00:00

abstract：:Succinate-driven reverse electron transport (RET) is one of the main sources of mitochondrial reactive oxygen species (mtROS) in ischemia-reperfusion injury. RET is dependent on mitochondrial membrane potential (Δψm) and transmembrane pH difference (ΔpH), components of the proton motive force (pmf); a decrease in Δψm ...

journal_title：Journal of bioenergetics and biomembranes

authors： Komlódi T,Geibl FF,Sassani M,Ambrus A,Tretter L

更新日期：2018-10-01 00:00:00

abstract：:The hexosamine biosynthetic pathway (HBP) integrates glucose, amino acids, fatty acids and nucleotides metabolisms for uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) synthesis. UDP-GlcNAc is the nucleotide sugar donor for O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) processes. O-GlcNAc transferase (OGT...

journal_title：Journal of bioenergetics and biomembranes

authors： Very N,Steenackers A,Dubuquoy C,Vermuse J,Dubuquoy L,Lefebvre T,El Yazidi-Belkoura I

更新日期：2018-06-01 00:00:00

abstract：:Hundreds of proteins in the nervous system are modified by the monosaccharide O-GlcNAc. A single protein is often O-GlcNAcylated on several amino acids and the modification of a single site can play a crucial role for the function of the protein. Despite its complexity, only two enzymes add and remove O-GlcNAc from pr...

journal_title：Journal of bioenergetics and biomembranes

authors： Lagerlöf O

更新日期：2018-06-01 00:00:00

abstract：:Subunit II of cytochrome c oxidase (Cox2) is usually encoded in the mitochondrial genome, synthesized in the organelle, inserted co-translationally into the inner mitochondrial membrane, and assembled into the respiratory complex. In chlorophycean algae however, the cox2 gene was split into the cox2a and cox2b genes, ...

journal_title：Journal of bioenergetics and biomembranes

authors： Jiménez-Suárez A,Vázquez-Acevedo M,Miranda-Astudillo H,González-Halphen D

更新日期：2017-12-01 00:00:00

abstract：:The mitochondrial UPR (UPRmt) is rapidly gaining attention. While most studies on the UPRmt have focused on its role in aging, emerging studies suggest an important role of the UPRmt in cancer. Further, several of the players of the UPRmt in mammalian cells have well reported roles in the maintenance of the organelle....

journal_title：Journal of bioenergetics and biomembranes

authors： Kenny TC,Germain D

更新日期：2017-08-01 00:00:00

abstract：:The production of all blood cells from hematopoietic stem cells (HSC) is highly sensitive to reactive oxygen species (ROS). Cumulating evidence suggests that mitochondria are critical for HSC fate determination. FOXO are known regulators of anti-oxidant response and key to the maintenance of HSC. Recent works indicate...

journal_title：Journal of bioenergetics and biomembranes

authors： Liang R,Ghaffari S

更新日期：2017-08-01 00:00:00

abstract：:The role of brain and liver mitochondria at epileptic seizure was studied on Krushinsky-Molodkina (KM) rats which respond to sound with an intensive epileptic seizure (audiogenic epilepsy). We didn't find significant changes in respiration rats of brain and liver mitochondria of KM and control rats; however the effici...

journal_title：Journal of bioenergetics and biomembranes

authors： Venediktova NI,Gorbacheva OS,Belosludtseva NV,Fedotova IB,Surina NM,Poletaeva II,Kolomytkin OV,Mironova GD

更新日期：2017-04-01 00:00:00

abstract：:Yeasts capable of growing and surviving at high temperatures are regarded as thermotolerant. For appropriate functioning of cellular processes and cell survival, the maintenance of an optimal redox state is critical of reducing and oxidizing species. We studied mitochondrial functions of the thermotolerant Kluyveromyc...

journal_title：Journal of bioenergetics and biomembranes

authors： Mejía-Barajas JA,Martínez-Mora JA,Salgado-Garciglia R,Noriega-Cisneros R,Ortiz-Avila O,Cortés-Rojo C,Saavedra-Molina A

更新日期：2017-04-01 00:00:00

abstract：:Mitochondria are responsible for many vital cellular functions in eukaryotic cells, such as ATP production, steroid synthesis and prosthetic group biogenesis. The vital functions of mitochondria are possible due to the compartmental nature of this organelle. Mitochondria form a dynamic network that can exist as a netw...

journal_title：Journal of bioenergetics and biomembranes

authors： McStay GP

更新日期：2017-02-01 00:00:00

abstract：:The adenylate kinase (AK) isoforms network plays an important role in the intracellular energy transfer processes, the maintenance of energy homeostasis, and it is a major player in AMP metabolic signaling circuits in some highly-differentiated cells. For this purpose, a rapid and sensitive method was developed that e...

journal_title：Journal of bioenergetics and biomembranes

authors： Klepinin A,Ounpuu L,Guzun R,Chekulayev V,Timohhina N,Tepp K,Shevchuk I,Schlattner U,Kaambre T

更新日期：2016-10-01 00:00:00

abstract：:Renal artery clamping itself induces renal ischemia which subsequently causes renal cell injury and can lead to renal failure. The duration of warm ischemia that would be safe for postoperative kidney function during partial nephrectomy remains under investigations. Mitochondria play an important role in pathophysiolo...

journal_title：Journal of bioenergetics and biomembranes

authors： Baniene R,Trumbeckas D,Kincius M,Pauziene N,Raudone L,Jievaltas M,Trumbeckaite S

更新日期：2016-02-01 00:00:00

abstract：:Heat shock protein 90 (Hsp90) is an attractive therapeutic target. Geldanamycin (GA), the first identified Hsp90 inhibitor, exhibited potent antitumor activity, but possessed significant hepatotoxicity. To overcome the hepatotoxicity derived from the quinone structure of GA, a non-quinone GA derivative 17-demethoxy-re...

journal_title：Journal of bioenergetics and biomembranes

authors： Zhao S,Li H,Jiang C,Ma T,Wu C,Huo Q,Liu H

更新日期：2015-10-01 00:00:00

abstract：:The serotonergic system plays a crucial role in the energy balance regulation. Energy balance is mediated by food intake and caloric expenditure. Thus, the present study investigated the mechanisms that might be associated with fluoxetine treatment-induced weight reduction. Wistar male rat pups received daily injectio...

journal_title：Journal of bioenergetics and biomembranes

authors： da Silva AI,Braz GR,Pedroza AA,Nascimento L,Freitas CM,Ferreira DJ,Manhães de Castro R,Lagranha CJ

更新日期：2015-08-01 00:00:00

abstract：:Since the nineteenth century, a great amount of different biological structures and processes have been assessed by fluorescent dyes. Along with the uses of these compounds as vital and histological dyes, some fluorescent dyes have become valuable tools for the study of the pore phenomenon in plasma membranes. Some io...

journal_title：Journal of bioenergetics and biomembranes

authors： Ferreira L,Pereira L,Faria R

更新日期：2015-08-01 00:00:00

abstract：:3-Bromopyruvate (3BP) is an energy-depleting drug that inhibits Hexokinase II activity by alkylation during glycolysis, thereby suppressing the production of ATP and inducing cell death. As such, 3BP can potentially serve as an anti-tumorigenic agent. Our previous research showed that 3BP can induce apoptosis via AKT ...

journal_title：Journal of bioenergetics and biomembranes

authors： Sun Y,Liu Z,Zou X,Lan Y,Sun X,Wang X,Zhao S,Jiang C,Liu H

更新日期：2015-08-01 00:00:00

abstract：:Traumatic brain injury (TBI) is still the leading cause of disability in young adults worldwide. The major mechanisms - diffuse axonal injury, cerebral contusion, ischemic neurological damage, and intracranial hematomas have all been shown to be associated with mitochondrial dysfunction in some form. Mitochondrial dys...

journal_title：Journal of bioenergetics and biomembranes

authors： Gajavelli S,Sinha VK,Mazzeo AT,Spurlock MS,Lee SW,Ahmed AI,Yokobori S,Bullock RM

更新日期：2015-04-01 00:00:00

abstract：:Due to the high metabolic demands of the placental tissue during gestation, we decide to analyzed the mitochondrial bioenergetic functions in the human term placenta. Different mitochondrial morphological parameters, membrane potential and cardiolipin content were determined by flow cytometry. Oxygen uptake, hydrogen ...

journal_title：Journal of bioenergetics and biomembranes

authors： Bustamante J,Ramírez-Vélez R,Czerniczyniec A,Cicerchia D,Aguilar de Plata AC,Lores-Arnaiz S

更新日期：2014-12-01 00:00:00

abstract：:Advanced glycation end products (AGEs) and methylglyoxal (MG), an important intermediate in AGEs synthesis, are thought to contribute to protein aging and to the pathogenesis of age-and diabetes-associated complications. This study was intended to investigate brain mitochondria bioenergetics and oxidative status of ra...

journal_title：Journal of bioenergetics and biomembranes

authors： Cardoso S,Carvalho C,Marinho R,Simões A,Sena CM,Matafome P,Santos MS,Seiça RM,Moreira PI

更新日期：2014-10-01 00:00:00

abstract：:Complex I (NDH-1) translocates protons across the membrane using electron transfer energy. Two different coupling mechanisms are currently being discussed for complex I: direct (redox-driven) and indirect (conformation-driven). Semiquinone (SQ) intermediates are suggested to be key for the coupling mechanism. Recently...

journal_title：Journal of bioenergetics and biomembranes

authors： Nakamaru-Ogiso E,Narayanan M,Sakyiama JA

更新日期：2014-08-01 00:00:00

abstract：:Increased membrane unsaturation has been associated with shorter longevity due to higher sensitivity to lipid peroxidation (LP) leading to enhanced mitochondrial dysfunction and ROS overproduction. However, the role of LP during aging has been put in doubt along with the participation of electron leak at the electron ...

journal_title：Journal of bioenergetics and biomembranes

authors： Aguilar-Toral R,Fernández-Quintero M,Ortiz-Avila O,de la Paz LH,Calderón-Cortés E,Rodríguez-Orozco AR,Saavedra-Molina A,Calderón-Torres M,Cortés-Rojo C

更新日期：2014-06-01 00:00:00

abstract：:Soy isoflavones are diphenolic compounds that are frequently used for alternative treatment of ageing symptoms in both genders. They operate at principally two hierarchical levels of functional organization - cellular and molecular, while these 'types' of action appear to have indefinite borders. Soy isoflavone action...

journal_title：Journal of bioenergetics and biomembranes

authors： Ajdžanović VZ,Medigović IM,Pantelić JB,Milošević VLj

更新日期：2014-04-01 00:00:00

abstract：:The multidrug resistance (MDR) phenotype, frequently observed during cancer treatment, is often associated with drug efflux pump activity. However, many other factors are also known to be involved. Cancer cells often rely on aerobic glycolysis for energy production; this is known as the "Warburg effect" and is used as...

journal_title：Journal of bioenergetics and biomembranes

authors： Tavares-Valente D,Baltazar F,Moreira R,Queirós O

更新日期：2013-10-01 00:00:00

abstract：:Mitochondria are dynamic structures for which fusion and fission are well characterized for rapidly dividing cells in culture. Based on these data, it has recently been proposed that high respiratory activity is the result of fusion and formation of mitochondrial reticulum, while fission results in fragmented mitochon...

journal_title：Journal of bioenergetics and biomembranes

authors： Varikmaa M,Guzun R,Grichine A,Gonzalez-Granillo M,Usson Y,Boucher F,Kaambre T,Saks V

更新日期：2013-08-01 00:00:00

abstract：:The molecular mechanism by which the membrane-embedded FO sector of the mitochondrial ATP synthase translocates protons, thus dissipating the transmembrane protonmotive force and leading to ATP synthesis, involves the neutralization of the carboxylate residues of the c-ring. Carboxylates are thought to constitute the ...

journal_title：Journal of bioenergetics and biomembranes

authors： Nesci S,Ventrella V,Trombetti F,Pirini M,Pagliarani A

更新日期：2013-06-01 00:00:00

abstract：:The development of new anti-neoplastic drugs is a key issue for cancer chemotherapy due to the reality that, most likely, certain cancer cells are resistant to current chemotherapy. The past two decades have witnessed tremendous advances in our understanding of the pathogenesis of cancer. These advances have allowed i...

journal_title：Journal of bioenergetics and biomembranes

authors： de Pedro N,Cautain B,Melguizo A,Vicente F,Genilloud O,Peláez F,Tormo JR

更新日期：2013-02-01 00:00:00

abstract：:NYGGF4 (also called PID1) is a recently discovered gene that is involved in obesity-related insulin resistance (IR). We aimed in the present study to further elucidate the effects of NYGGF4 on IR and the underlying mechanisms through using metformin treatment in 3T3-L1 adipocytes. Our data showed that the metformin pr...

journal_title：Journal of bioenergetics and biomembranes

authors： Qiu J,Wang YM,Shi CM,Yue HN,Qin ZY,Zhu GZ,Cao XG,Ji CB,Cui Y,Guo XR

更新日期：2012-12-01 00:00:00

abstract：:This introductory article and those that follow focus on the roles that mitochondria may have in cancer metastasis (spreading) that all too frequently leads to death of cancer patients. The history of cancer dates back in time to several thousand years BC and continues to this day. Although billions of dollars have be...

journal_title：Journal of bioenergetics and biomembranes

authors： Pedersen PL

更新日期：2012-12-01 00:00:00

abstract：:Overexpression of the Homo sapiens LYR motif containing 1 (LYRM1) causes mitochondrial dysfunction and induces insulin resistance in 3T3-L1 adipocytes. α-Lipoic acid (α-LA), a dithiol compound with antioxidant properties, improves glucose transport and utilization in 3T3-L1 adipocytes. The aim of this study was to inv...

journal_title：Journal of bioenergetics and biomembranes

authors： Qin ZY,Zhang M,Guo XR,Wang YM,Zhu GZ,Ni YH,Zhao YP,Qiu J,Kou CZ,Qin R,Cao XG

更新日期：2012-10-01 00:00:00