Vacuolar H+ pumping ATPases in luminal acidic organelles and extracellular compartments: common rotational mechanism and diverse physiological roles.

abstract：:Phosphatase activity of a kidney (Na + K)-ATPase preparation was optimally active with Mg2+ plus K+. Mn2+ was less effective and Ca2+ could not substitute for Mg2+. However, adding Ca2+ with Mg2+ or substituting Mn2+ for Mg2+ activated it appreciably in the absence of added K+, and all three divalent cations decreased...

journal_title：Journal of bioenergetics and biomembranes

authors： Robinson JD

更新日期：1985-06-01 00:00:00

abstract：:The role of nucleoside diphosphate (NDP) kinase with special reference to mammalian signal transduction systems was described. The interaction between NDP kinases and G proteins was reevaluated in view of their protein structural information and its significance was extended further on the basis of recent findings obt...

journal_title：Journal of bioenergetics and biomembranes

authors： Kimura N,Shimada N,Ishijima Y,Fukuda M,Takagi Y,Ishikawa N

更新日期：2003-02-01 00:00:00

abstract：:The total amount of cellular mitochondrial DNA (mtDNA) varies widely and seems to be related to the nature and metabolic state of tissues and cells in culture. It is not known, however, whether this variation has any significance in vivo, and to which extent it regulates energy production. To better understand the imp...

journal_title：Journal of bioenergetics and biomembranes

authors： Rocher C,Taanman JW,Pierron D,Faustin B,Benard G,Rossignol R,Malgat M,Pedespan L,Letellier T

更新日期：2008-04-01 00:00:00

abstract：:We have studied a mutant strain of Drosophila in which 80% of the mitochondrial DNA molecules have lost over 30% of their coding region through deletion. This deletion affects genes encoding five subunits of complex I of the respiratory chain (NADH:ubiquinone oxidoreductase). The enzymatic activity of complex I in the...

journal_title：Journal of bioenergetics and biomembranes

authors： Farge G,Touraille S,Lachaume P,Debise R,Procaccio V,Alziari S

更新日期：2004-04-01 00:00:00

abstract：:The ATP synthetase of chloroplast membranes binds ADP and ATP with high affinity, and the binding becomes quasi-irreversible under certain conditions. One explanation of the function of these nucleotides is that they are transiently tightly bound during ATP synthesis as part of the catalytic process, and that the rele...

journal_title：Journal of bioenergetics and biomembranes

authors： Tiefert MA,Shavit N

更新日期：1983-10-01 00:00:00

abstract：:The plasma membrane-enriched fraction isolated from smooth muscle of rat gastric fundus was found to contain a substantial level of potassium-stimulated p-nitrophenylphosphatase activity (K-pNPPase), and its subcellular distribution closely resembled that of other plasma membrane enzyme markers. The kinetic profile of...

journal_title：Journal of bioenergetics and biomembranes

authors： Kostka P,Kwan CY

更新日期：1986-08-01 00:00:00

abstract：:The mitochondrial inner membrane anion channel (IMAC) is a channel, identified by flux studies in intact mitochondria, which has a broad anion selectivity and is maintained closed or inactive by matrix Mg2+ and H+. We now present evidence that this channel, like many other chloride/anion channels, is reversibly blocke...

journal_title：Journal of bioenergetics and biomembranes

authors： Beavis AD,Davatol-Hag H

更新日期：1996-04-01 00:00:00

abstract：:Forkhead box protein O6 (FOXO6) has been recently identified as a novel regulator of oxidative stress in multiple pathological processes. However, whether FOXO6 participates in the regulation of oxidative stress of myocardial infarction is unclear. The present study was performed to evaluate the potential role of FOXO...

journal_title：Journal of bioenergetics and biomembranes

authors： Jin A,Zhang Q,Li S,Li B

更新日期：2020-12-01 00:00:00

abstract：:The sarcoplasmic reticulum (SR) of skeletal muscle controls the contraction-relaxation cycle by raising and lowering the myoplasmic free-Ca2+ concentration. The coupling between excitation, i.e., depolarization of sarcolemma and transverse tubule (TT) and Ca2+ release from the terminal cisternae (TC) of SR takes place...

journal_title：Journal of bioenergetics and biomembranes

authors： Volpe P

更新日期：1989-04-01 00:00:00

abstract：:Bioenergetics of tomato (Lycopersicon esculentum) development on the plant was followed from the early growing stage to senescence in wild type (climacteric) and nonripening mutant (nor, non-climacteric) fruits. Fruit development was expressed in terms of evolution of chlorophyll a content allowing the assessment of a...

journal_title：Journal of bioenergetics and biomembranes

authors： Almeida AM,Navet R,Jarmuszkiewicz W,Vercesi AE,Sluse-Goffart CM,Sluse FE

更新日期：2002-12-01 00:00:00

abstract：:Signal peptidases, the endoproteases that remove the amino-terminal signal sequence from many secretory proteins, have been isolated from various sources. Seven signal peptidases have been purified, two from E. coli, two from mammalian sources, and three from mitochondrial matrix. The mitochondrial enzymes are soluble...

journal_title：Journal of bioenergetics and biomembranes

authors： Dev IK,Ray PH

更新日期：1990-06-01 00:00:00

abstract：:Thirteen different polypeptide subunits, each in one copy, five phosphatidyl ethanolamines and three phosphatidyl glycerols, two hemes A, three Cu ions, one Mg ion, and one Zn ion are detectable in the crystal structure of bovine heart cytochrome c oxidase in the fully oxidized form at 2.8 A resolution. A propionate o...

journal_title：Journal of bioenergetics and biomembranes

authors： Yoshikawa S,Shinzawa-Itoh K,Tsukihara T

更新日期：1998-02-01 00:00:00

abstract：:For the past seven years or so, much discussion and controversy in the field of human evolution has revolved around the application and interpretation of studies of human mitochondrial DNA variation, particularly the hypothesis that all mtDNA types in contemporary populations can be traced back to a single African anc...

journal_title：Journal of bioenergetics and biomembranes

authors： Stoneking M

更新日期：1994-06-01 00:00:00

abstract：:Research on VDAC has accelerated as evidence grows of its importance in mitochondrial function and in apoptosis. New investigators entering the field are often confounded by the VDAC literature and its many apparent conflicts and contradictions. This review is an effort to shed light on the situation and identify reli...

journal_title：Journal of bioenergetics and biomembranes

authors： Rostovtseva TK,Tan W,Colombini M

更新日期：2005-06-01 00:00:00

abstract：:Idebenone (IDE), a synthetic analog of coenzyme Q, strongly activates glycerol phosphate (GP) oxidation in brown adipose tissue mitochondria. GP oxidase, GP cytochrome c oxidoreductase and GP dehydrogenase activities were all significantly stimulated by 13 muM IDE. Substituted derivatives of IDE acetyl- and methoxyide...

journal_title：Journal of bioenergetics and biomembranes

authors： Rauchová H,Drahota Z,Bergamini C,Fato R,Lenaz G

更新日期：2008-04-01 00:00:00

abstract：:Bacillus subtilis has a bifurcated respiratory chain composed of a cytochrome branch and a quinol oxidase branch. The respiratory complexes of this bacterium have been elucidated mostly by the analysis of the genome and by the isolation of individual complexes. The supramolecular organization of this respiratory chain...

journal_title：Journal of bioenergetics and biomembranes

authors： García Montes de Oca LY,Chagolla-López A,González de la Vara L,Cabellos-Avelar T,Gómez-Lojero C,Gutiérrez Cirlos EB

更新日期：2012-08-01 00:00:00

abstract：:The hexosamine biosynthetic pathway (HBP) integrates glucose, amino acids, fatty acids and nucleotides metabolisms for uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) synthesis. UDP-GlcNAc is the nucleotide sugar donor for O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) processes. O-GlcNAc transferase (OGT...

journal_title：Journal of bioenergetics and biomembranes

authors： Very N,Steenackers A,Dubuquoy C,Vermuse J,Dubuquoy L,Lefebvre T,El Yazidi-Belkoura I

更新日期：2018-06-01 00:00:00

abstract：:We report on the influence of dielectric pulse injection on the energy metabolism of yeast cells with a planar interdigitated electrode interface. The energy metabolism was measured via NADH fluorescence. The application of dielectric pulses results in a distinct decrease of the fluorescence, indicating a response of ...

journal_title：Journal of bioenergetics and biomembranes

authors： Reiher A,Warnke C,Radoch S,Witte H,Krtschil A,Mair T,Müller SC,Krost A

更新日期：2006-04-01 00:00:00

abstract：:We studied the importance of respiratory fitness in S. cerevisiae lifespan, response to caloric restriction (CR) and mtDNA stability. Mutants harboring mtDNA instability and electron transport defects do not respond to CR, while tricarboxylic acid cycle mutants presented extended lifespans due to CR. Interestingly, mt...

journal_title：Journal of bioenergetics and biomembranes

authors： Tahara EB,Cezário K,Souza-Pinto NC,Barros MH,Kowaltowski AJ

更新日期：2011-10-01 00:00:00

abstract：:Beef heart cytochrome c oxidase was reconstituted in asolectin liposomes containing the pH indicator fluorescein-phosphatidylethanolamine (FPE) by the cholate-dialysis procedure. The influence of FPE on the asolectin liposome size and of the removal of subunit III from the complex on its incorporation into liposomes w...

journal_title：Journal of bioenergetics and biomembranes

authors： Müller M,Azzi A

更新日期：1985-12-01 00:00:00

abstract：:Both cellular proliferation and apoptosis (programmed cell death) have been claimed to be modulated, perhaps even triggered by, changes in intracellular pH. In this review, we summarize the evidence that gave rise to these hypotheses. To facilitate a critical appraisal of the existing data, we briefly review the main ...

journal_title：Journal of bioenergetics and biomembranes

authors： Shrode LD,Tapper H,Grinstein S

更新日期：1997-08-01 00:00:00

abstract：:The protons excreted by plant cells may arise by two different mechanisms: (1) by the action of the plasma membrane H(+)-ATPase and (2) by plasma membrane redox reactions. The exact proportion from each source is not known, but the plasma membrane H(+)-ATPase is, by far, the major contributor to proton efflux. There i...

journal_title：Journal of bioenergetics and biomembranes

authors： Barr R

更新日期：1991-06-01 00:00:00

abstract：:Vicious cycle theories of aging and oxidative stress propose that ROS produced by the mitochondrial electron transport chain damage the mitochondria leading exponentially to more ROS production and mitochondrial damage. Although this theory is widely discussed in the field of research on aging and oxidative stress, th...

journal_title：Journal of bioenergetics and biomembranes

authors： Sanz A,Caro P,Gómez J,Barja G

更新日期：2006-04-01 00:00:00

abstract：:Bacterial growth at the extremes of temperature has remained a fascinating aspect in the study of membrane function and structure. The stability of the integral membrane proteins of thermophiles make them particularly amenable to study. Respiratory enzymes of thermophiles appear to be functionally similar to the mesop...

journal_title：Journal of bioenergetics and biomembranes

authors： Konings WN,Tolner B,Speelmans G,Elferink MG,de Wit JG,Driessen AJ

更新日期：1992-12-01 00:00:00

abstract：:A rapid loss of accumulated Ca2+ is produced by addition of H+ to isolated heart mitochondria. The H+-dependent Ca+ efflux requires that either (a) the NAD(P)H pool of the mitochondrion be oxidized, or (b) the endogenous adenine nucleotides be depleted. The loss of Ca2+ is accompanied by swelling and loss of endogenou...

journal_title：Journal of bioenergetics and biomembranes

authors： Jurkowitz MS,Brierley GP

更新日期：1982-12-01 00:00:00

abstract：:During fermentation Escherichia coli transport succinate mainly via Dcu family carriers. Current paper describes the role of externally added succinate on N'N'-dicyclohexylcarbodiimide (DCCD) sensitive ATPase activity and H+ flux depending on potassium ions. At pH 7.5 in wild type membrane vesicles DCCD-sensitive ATPa...

journal_title：Journal of bioenergetics and biomembranes

authors： Mikoyan G,Karapetyan L,Vassilian A,Trchounian A,Trchounian K

更新日期：2020-10-01 00:00:00

abstract：:We have studied changes in plasma membrane NAD(P)H:quinone oxidoreductases of HL-60 cells under serum withdrawal conditions, as a model to analyze cell responses to oxidative stress. Highly enriched plasma membrane fractions were obtained from cell homogenates. A major part of NADH-quinone oxidoreductase in the plasma...

journal_title：Journal of bioenergetics and biomembranes

authors： Forthoffer N,Gómez-Díaz C,Bello RI,Burón MI,Martín SF,Rodríguez-Aguilera JC,Navas P,Villalba JM

更新日期：2002-06-01 00:00:00

abstract：:Free radical production and leak of brain nonsynaptic mitochondria were higher with pyruvate/malate than with succinate in rats and pigeons. Rotenone, antimycin A, and myxothiazol maximally stimulated free radical production with pyruvate/malate but not with succinate. Simultaneous treatment with myxothiazol plus anti...

journal_title：Journal of bioenergetics and biomembranes

authors： Barja G,Herrero A

更新日期：1998-06-01 00:00:00

abstract：:Mitochondria are dynamic structures for which fusion and fission are well characterized for rapidly dividing cells in culture. Based on these data, it has recently been proposed that high respiratory activity is the result of fusion and formation of mitochondrial reticulum, while fission results in fragmented mitochon...

journal_title：Journal of bioenergetics and biomembranes

authors： Varikmaa M,Guzun R,Grichine A,Gonzalez-Granillo M,Usson Y,Boucher F,Kaambre T,Saks V

更新日期：2013-08-01 00:00:00

abstract：:First, halorhodopsin is capable of pumping protons after illumination with green and blue light in the same direction as chloride. Second, mutated bacteriorhodopsin where the proton acceptor Asp85 and the proton donor Asp96 are replaced by Asn showed proton pump activity after illumination with blue light in the same ...

journal_title：Journal of bioenergetics and biomembranes

authors： Oesterhelt D,Tittor J,Bamberg E

更新日期：1992-04-01 00:00:00