Antipain lethality to Escherichia coli: dependence upon cyclic adenosine 3',5'-monophosphate and its receptor protein.

Abstract:

:Antipain kills Escherichia coli K-12 cells in an exponential manner beginning 1 h after its addition. Mutant strains, delta cya and crp, which are unable to synthesize cyclic adenosine 3',5'-monophosphate (cAMP) and the cAMP receptor protein, respectively, are not affected. Addition of cAMP (5 mM) to antipain-treated mutant strains causes killing of delta cya cells, but not crp cells. Thus the lethal effect of antipain is dependent upon cAMP and its receptor protein.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Swenson PA

doi

10.1128/JB.139.2.690-693.1979

subject

Has Abstract

pub_date

1979-08-01 00:00:00

pages

690-3

issue

2

eissn

0021-9193

issn

1098-5530

journal_volume

139

pub_type

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