Subanaesthetic ketamine treatment alters prefrontal cortex connectivity with thalamus and ascending subcortical systems.

abstract：:The purpose of this study was to assess how neurocognition and social cognition were associated with initial functional level and with rates of functional change in intensive community-based psychosocial rehabilitation interventions that have been shown to yield significant functional change for individuals diagnosed ...

journal_title：Schizophrenia bulletin

authors： Brekke JS,Hoe M,Long J,Green MF

更新日期：2007-09-01 00:00:00

abstract：INTRODUCTION:ABT-288 is a highly potent histamine-3 receptor antagonist that has demonstrated pro-cognitive effects in preclinical models relevant to schizophrenia. This study evaluated the efficacy and safety of two doses of ABT-288 in the treatment of cognitive impairment associated with schizophrenia. METHODS:A ran...

journal_title：Schizophrenia bulletin

authors： Haig GM,Bain E,Robieson W,Othman AA,Baker J,Lenz RA

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:Cannabis use is associated with a younger age at onset of psychosis, an indicator of poor prognosis, but better cognitive function, a positive prognostic indicator. We aimed to clarify the role of age at onset and cognition on outcomes in cannabis users with first-episode schizophrenia as well as the effect o...

journal_title：Schizophrenia bulletin

authors： Leeson VC,Harrison I,Ron MA,Barnes TR,Joyce EM

更新日期：2012-06-01 00:00:00

abstract：:The article that follows is part of the Schizophrenia Bulletin's ongoing First Person Accounts series. We hope that mental health professionals--the Bulletin's primary audience--will take this opportunity to learn about the issues and difficulties confronted by consumers of mental health care. In addition, we hope tha...

journal_title：Schizophrenia bulletin

authors： Bowden WD

更新日期：1993-01-01 00:00:00

abstract：:Although weight gain is a serious but variable adverse effect of antipsychotics that has genetic underpinnings, a comprehensive meta-analysis of pharmacogenetics of antipsychotic-related weight gain is missing. In this review, random effects meta-analyses were conducted for dominant and recessive models on association...

journal_title：Schizophrenia bulletin

authors： Zhang JP,Lencz T,Zhang RX,Nitta M,Maayan L,John M,Robinson DG,Fleischhacker WW,Kahn RS,Ophoff RA,Kane JM,Malhotra AK,Correll CU

更新日期：2016-11-01 00:00:00

abstract：:North American outcome studies of schizophrenia conducted within the past quarter century are reviewed if their minimum average followup is 10 years and they meet at least some modern design criteria. Ten such investigations are described and summarized. Taken as a whole, they demonstrate that schizophrenia can be a c...

journal_title：Schizophrenia bulletin

authors： McGlashan TH

更新日期：1988-01-01 00:00:00

abstract：:Individuals with psychoses have brain alterations, particularly in frontal and temporal cortices, that may be particularly prominent, already at illness onset, in those more likely to have poorer symptom remission following treatment with the first antipsychotic. The identification of strong neuroanatomical markers of...

journal_title：Schizophrenia bulletin

authors： Dazzan P,Lawrence AJ,Reinders AATS,Egerton A,van Haren NEM,Merritt K,Barker GJ,Perez-Iglesias R,Sendt KV,Demjaha A,Nam KW,Sommer IE,Pantelis C,Wolfgang Fleischhacker W,van Rossum IW,Galderisi S,Mucci A,Drake R,Lewis S

更新日期：2020-10-15 00:00:00

abstract：:A frontostriatal hypothesis of schizophrenia is advanced which takes into account evidence from studies of neurochemical pathology, functional imaging, cognitive neuropsychology, and experimental and clinical psychopharmacology, in addition to factor analyses of the symptomatic heterogeneity of this disorder. This evi...

journal_title：Schizophrenia bulletin

authors： Robbins TW

更新日期：1990-01-01 00:00:00

abstract：:The association between low birth weight and schizophrenia has been suggested by many studies. Small for gestational age (SGA) is a measure used as a proxy for intrauterine growth restriction. We aim to examine if children who are born SGA are at increased risk of developing schizophrenia and whether an association ma...

journal_title：Schizophrenia bulletin

authors： Nielsen PR,Mortensen PB,Dalman C,Henriksen TB,Pedersen MG,Pedersen CB,Agerbo E

更新日期：2013-11-01 00:00:00

abstract：:In a previous article in the Schizophrenia Bulletin (Vol. 22, No. 1, 1996), we presented findings of a study on the clinical and rehabilitative effects of work activity on 150 subjects diagnosed with schizophrenia or schizoaffective disorder. Subjects were randomly assigned to either a Pay ($3.40/hr) or No-Pay group a...

journal_title：Schizophrenia bulletin

authors： Bell MD,Lysaker PH

更新日期：1997-01-01 00:00:00

abstract：:This commentary on the updated Patient Outcomes Research Team recommendation from a policy perspective notes that the quality of research recommendations is improved but that there has been only limited impact and utility for providers. ...

journal_title：Schizophrenia bulletin

authors： Hogan M

更新日期：2010-01-01 00:00:00

abstract：:Problems in psychiatric classification have impeded research into psychopathology for more than a century. Here, I briefly review several new approaches to solving this problem, including the internalizing-externalizing-psychosis spectra, the 5-factor model of psychotic symptoms, and the more recent network approach. ...

journal_title：Schizophrenia bulletin

authors： Bentall RP

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Similar to patients with other chronic disorders, patients with serious mental illness (SMI) are often poorly adherent with prescribed medications. OBJECTIVE:We conducted a randomized controlled trial examining the effectiveness of a pharmacy-based intervention (Meds-Help) in increasing antipsychotic medica...

journal_title：Schizophrenia bulletin

authors： Valenstein M,Kavanagh J,Lee T,Reilly P,Dalack GW,Grabowski J,Smelson D,Ronis DL,Ganoczy D,Woltmann E,Metreger T,Wolschon P,Jensen A,Poddig B,Blow FC

更新日期：2011-07-01 00:00:00

abstract：:Deluded people differ from nondeluded controls on attributional style questionnaires and probabilistic-reasoning and theory-of-mind (ToM) tasks. No study to date has examined the relations between these 3 reasoning anomalies in the same individuals so as to evaluate their functional independence and potentially inform...

journal_title：Schizophrenia bulletin

authors： Langdon R,Ward PB,Coltheart M

更新日期：2010-03-01 00:00:00

abstract：:The rate of substance-use disorders in patients with mental illnesses within the psychotic spectrum, such as schizophrenia, schizoaffective disorder, and bipolar disorder, is higher than the rate observed in the general population and is associated with significant morbidity and mortality. Although there are currently...

journal_title：Schizophrenia bulletin

authors： Petrakis IL,Nich C,Ralevski E

更新日期：2006-10-01 00:00:00

abstract：:Delusions, the fixed false beliefs characteristic of psychotic illness, have long defied understanding despite their response to pharmacological treatments (e.g., D2 receptor antagonists). However, it can be challenging to discern what makes beliefs delusional compared with other unusual or erroneous beliefs. We sugge...

journal_title：Schizophrenia bulletin

authors： Feeney EJ,Groman SM,Taylor JR,Corlett PR

更新日期：2017-03-01 00:00:00

abstract：:Previous studies have reported associations between childhood adversities, eg, loss of a parent, being raised in institutional care, sexual and other kinds of abuse by adults and bullying by peers, and psychosis in adulthood. However, the mechanisms by which these adversities lead to psychotic experiences are poorly u...

journal_title：Schizophrenia bulletin

authors： Bentall RP,Wickham S,Shevlin M,Varese F

更新日期：2012-06-01 00:00:00

abstract：:While previous studies have found an increased incidence of schizophrenia in some immigrant groups, differences in age of onset in these groups has not been examined. The purpose of this study was to compare age of first hospitalization of (1) native-born people versus immigrants, (2) immigrants from different countri...

journal_title：Schizophrenia bulletin

authors： Rabinowitz J,Fennig S

更新日期：2002-01-01 00:00:00

abstract：:This analysis examines the notion of progressive deterioration in schizophrenia, using long-term followup data on hospital episodes in defined cohorts from psychiatric case registers in Victoria, Australia; Denmark; and Salford, England. The analyses differentiate heterogeneity existing at the first hospitalization fo...

journal_title：Schizophrenia bulletin

authors： Eaton WW,Bilker W,Haro JM,Herrman H,Mortensen PB,Freeman H,Burgess P

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Insight into the neural mechanisms underlying the shared and disparate features of schizophrenia (SZ) and bipolar disorder (BD) is limited. The amygdala and prefrontal cortex (PFC) appear to have crucial roles in SZ and BD, yet abnormalities appear to manifest differently in the 2 disorders. METHODS:Eightee...

journal_title：Schizophrenia bulletin

authors： Liu H,Tang Y,Womer F,Fan G,Lu T,Driesen N,Ren L,Wang Y,He Y,Blumberg HP,Xu K,Wang F

更新日期：2014-03-01 00:00:00

abstract：:The issue of specificity of delusions in schizophrenia is still a matter of debate. The authors analyze the delusion formation in schizophrenia from a prototypical, phenomenological point of view, focusing on the subject's experience. This perspective links delusion formation to the autistic predisposition, which is c...

journal_title：Schizophrenia bulletin

authors： Bovet P,Parnas J

更新日期：1993-01-01 00:00:00

abstract：:The role of gender in schizophrenia is explored, and literature on gender and schizophrenia is critically reviewed. The importance of investigating gender differences in schizophrenia is underscored by the lack of sufficient research in this area to date and the comparative neglect of sociocultural issues during the "...

journal_title：Schizophrenia bulletin

authors： Nasser EH,Walders N,Jenkins JH

更新日期：2002-01-01 00:00:00

abstract：:The apparent neglect of neuropsychologic deficits in schizophrenia as the basis for therapeutic intervention, together with only isolated attempts at remediating them, probably reflect the nature of impairments, the functional significance of which is uncertain. A critique of the limitations inherent in the appealing ...

journal_title：Schizophrenia bulletin

authors： Hogarty GE,Flesher S

更新日期：1992-01-01 00:00:00

abstract：:The left superior temporal sulcus (STS) plays an important role in integrating audiovisual information and is functionally connected to disparate regions of the brain. For the integration of gesture information in an abstract sentence context (metaphoric gestures), intact connectivity between the left STS and the infe...

journal_title：Schizophrenia bulletin

authors： Straube B,Green A,Sass K,Kircher T

更新日期：2014-07-01 00:00:00

abstract：:Patients with schizophrenia can sometimes report strange face illusions when staring at themselves in the mirror; such experiences have been conceptualized as anomalous self-experiences that can be experienced with a varying degree of depersonalization. During adolescence, anomalous self-experiences can also be indica...

journal_title：Schizophrenia bulletin

authors： Fonseca-Pedrero E,Badoud D,Antico L,Caputo GB,Eliez S,Schwartz S,Debbané M

更新日期：2015-03-01 00:00:00

abstract：:Cognitive remediation improves cognition in patients with schizophrenia, but its effect on other relevant factors such as negative symptoms and functional outcome has not been extensively studied. In this hospital-based study, 84 inpatients with chronic schizophrenia were recruited from Alava Hospital (Spain). All of ...

journal_title：Schizophrenia bulletin

authors： Sánchez P,Peña J,Bengoetxea E,Ojeda N,Elizagárate E,Ezcurra J,Gutiérrez M

更新日期：2014-05-01 00:00:00

abstract：:Spatial working memory (WM) processing has 3 distinct phases: encoding, maintenance, and retrieval and its dysfunction is a core feature in schizophrenia. We examined phase-specific brain activations associated with spatial WM in first-degree relatives of schizophrenia (genetic high risk, GHR), ultra-high risk (UHR) s...

journal_title：Schizophrenia bulletin

authors： Choi JS,Park JY,Jung MH,Jang JH,Kang DH,Jung WH,Han JY,Choi CH,Hong KS,Kwon JS

更新日期：2012-11-01 00:00:00

abstract：:Cognitive models of interpersonal problem solving have been proposed for, but infrequently tested on, samples of schizophrenia subjects. This study undertook to examine the relationships between the receiving, processing, and sending skills that comprise one model of interpersonal problem solving with information proc...

journal_title：Schizophrenia bulletin

authors： Corrigan PW,Toomey R

更新日期：1995-01-01 00:00:00

abstract：:Every year numerous reports on antipsychotic drug trials are being published in neuropsychiatric journals, adding new information to our knowledge in the field. The information however is often hard for the reader to interpret, sometimes contradictory to comparable available studies and leaves more questions open than...

journal_title：Schizophrenia bulletin

authors： Leucht S,Heres S,Hamann J,Kane JM

更新日期：2008-03-01 00:00:00

abstract：:Schizotypal disorder is characterized by odd behavior and attenuated forms of schizophrenic features without the manifestation of overt and sustained psychoses. Past studies suggest that schizotypal disorder shares biological and psychological commonalties with schizophrenia. Structural magnetic resonance imaging (MRI...

journal_title：Schizophrenia bulletin

authors： Takayanagi Y,Sasabayashi D,Takahashi T,Furuichi A,Kido M,Nishikawa Y,Nakamura M,Noguchi K,Suzuki M

更新日期：2020-02-26 00:00:00