Abstract:
:Linking observed and executable actions appears to be achieved by an action observation network (AON), comprising parietal, premotor, and occipitotemporal cortical regions of the human brain. AON engagement during action observation is thought to aid in effortless, efficient prediction of ongoing movements to support action understanding. Here, we investigate how the AON responds when observing and predicting actions we cannot readily reproduce before and after visual training. During pre- and posttraining neuroimaging sessions, participants watched gymnasts and wind-up toys moving behind an occluder and pressed a button when they expected each agent to reappear. Between scanning sessions, participants visually trained to predict when a subset of stimuli would reappear. Posttraining scanning revealed activation of inferior parietal, superior temporal, and cerebellar cortices when predicting occluded actions compared to perceiving them. Greater activity emerged when predicting untrained compared to trained sequences in occipitotemporal cortices and to a lesser degree, premotor cortices. The occipitotemporal responses when predicting untrained agents showed further specialization, with greater responses within body-processing regions when predicting gymnasts' movements and in object-selective cortex when predicting toys' movements. The results suggest that (1) select portions of the AON are recruited to predict the complex movements not easily mapped onto the observer's body and (2) greater recruitment of these AON regions supports prediction of less familiar sequences. We suggest that the findings inform both the premotor model of action prediction and the predictive coding account of AON function.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Cross ES,Stadler W,Parkinson J,Schütz-Bosbach S,Prinz Wdoi
10.1002/hbm.21450subject
Has Abstractpub_date
2013-02-01 00:00:00pages
467-86issue
2eissn
1065-9471issn
1097-0193journal_volume
34pub_type
杂志文章abstract::Mathematical word problems are ubiquitous and standard for teaching and evaluating generalization of mathematical knowledge for real-world contexts. It is therefore concerning that the neural mechanisms of word problem solving are not well understood, as these insights represent strong potential for improving educatio...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24502
更新日期:2019-04-15 00:00:00
abstract::The development of language, social interaction, and communicative skills are remarkably different in the child with autism spectrum disorder (ASD). Atypical brain connectivity has frequently been reported in this patient population. However, the interplay between their brain connectivity and language performance rema...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22424
更新日期:2014-08-01 00:00:00
abstract::We present a novel, computerized method of examining cerebral cortical thickness. The normal cortex varies in thickness from 2 to 4 mm, reflecting the morphology of neuronal sublayers. Cortical pathologies often manifest abnormal variations in thickness, with examples of Alzheimer's disease and cortical dysplasia as t...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/1097-0193(200009)11:1<12::aid-hbm20>3.0.co
更新日期:2000-09-01 00:00:00
abstract::Carpal tunnel syndrome (CTS) is a common entrapment neuropathy of the median nerve characterized by paresthesias and pain in the first through fourth digits. We hypothesize that aberrant afferent input from CTS will lead to maladaptive cortical plasticity, which may be corrected by appropriate therapy. Functional MRI ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20261
更新日期:2007-03-01 00:00:00
abstract::It is widely accepted that abnormalities in the frontal area of the brain underpin the pathophysiology of obsessive-compulsive disorder (OCD). Fundamental to this investigation is the delineation of frontal white matter tracts including dorsal and ventral frontal projections of interhemispheric connections. While prev...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21372
更新日期:2012-10-01 00:00:00
abstract::Patients with schizophrenia have patterns of brain deficits including reduced cortical thickness, subcortical gray matter volumes, and cerebral white matter integrity. We proposed the regional vulnerability index (RVI) to translate the results of Enhancing Neuro Imaging Genetics Meta-Analysis studies to the individual...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25045
更新日期:2020-05-28 00:00:00
abstract::The Disrupted in Schizophrenia Gene 1 (DISC1) plays a role in both neural signaling and development and is associated with schizophrenia, although its links to altered brain structure and function in this disorder are not fully established. Here we have used structural and functional MRI to investigate links with six ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22560
更新日期:2014-11-01 00:00:00
abstract::The sulcal morphology of the human frontal lobe is highly variable. Although the structural images usually acquired in functional magnetic resonance imaging studies provide information about this interindividual variability, this information is only rarely used to relate structure and function. Here, we investigated t...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20501
更新日期:2009-01-01 00:00:00
abstract::The dorsal attention network (DAN), including frontal eye fields and posterior parietal cortices, and its link with the posterior thalamus, contribute to visual-spatial abilities. Very premature birth impairs both visual-spatial abilities and cortico-thalamic structural connectivity. We hypothesized that impaired stru...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24685
更新日期:2019-10-01 00:00:00
abstract::Cortical hubs play a fundamental role in the functional architecture of brain connectivity at rest. However, the anatomical scaffold underlying their centrality is still under debate. Certainly, the brain function and anatomy are significantly entwined through synaptogenesis and pruning mechanisms that continuously re...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23721
更新日期:2017-10-01 00:00:00
abstract::The control system in human brain generally exerts the goal-directed regulation on a variety of mental processes. To deal with different control demands, these brain areas of the control system, especially the dorsolateral prefrontal cortex (DLPFC), may be flexibly recruited across different tasks. However, few studie...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24313
更新日期:2018-12-01 00:00:00
abstract::We used emotional expectancy to study attentional modulation in the processing of emotional stimuli. During functional magnetic resonance imaging (fMRI), volunteers saw emotional and neutral expectancy cues signaling the subsequent presentation of corresponding emotional or neutral pictorial stimuli. As a control, emo...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20209
更新日期:2006-08-01 00:00:00
abstract::The question of how spatially organized activity in the visual cortex behaves during eyes-closed, lysergic acid diethylamide (LSD)-induced "psychedelic imagery" (e.g., visions of geometric patterns and more complex phenomena) has never been empirically addressed, although it has been proposed that under psychedelics, ...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章
doi:10.1002/hbm.23224
更新日期:2016-08-01 00:00:00
abstract::The literature points to a large distributed brain network involved in the estimation of time. Among these regions, the role of the insular cortex is still poorly understood. At the confluence of emotional, interoceptive, and environmental signals, this brain structure has been proposed to underlie awareness of the pa...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24460
更新日期:2019-04-01 00:00:00
abstract::Brain morphometry based classification from magnetic resonance (MR) acquisitions has been widely investigated in the diagnosis of Alzheimer's disease (AD) and its prodromal stage, i.e., mild cognitive impairment (MCI). In the literature, a morphometric representation of brain structures is obtained by spatial normaliz...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22531
更新日期:2014-10-01 00:00:00
abstract::BOLD functional MRI (fMRI) data are dominated by low frequency signals, many of them of unclear origin. We have recently shown that some portions of the low frequency oscillations found in BOLD fMRI are systemic signals closely related to the blood circulation (Tong et al. [2013]: NeuroImage 76:202-215). They are comm...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22564
更新日期:2014-11-01 00:00:00
abstract::Mounting evidence indicates that serum cholesterol and other risk factors for cardiovascular disease intensify normative trajectories of age-related cognitive decline. However, the neural mechanisms by which this occurs remain largely unknown. To understand the impact of cholesterol on brain networks, we applied graph...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23587
更新日期:2017-06-01 00:00:00
abstract::Neuroimaging investigations consistently demonstrate that the neural processes involve complex interactions between the large-scale networks. Among those networks, the dorsal attention network (DAN) and the central-executive network (CEN) have been previously shown to exhibit anti-correlated activity with the default-...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24339
更新日期:2018-12-01 00:00:00
abstract::The concept of brain maintenance refers to the preservation of brain integrity in older age, while cognitive reserve refers to the capacity to maintain cognition in the presence of neurodegeneration or aging-related brain changes. While both mechanisms are thought to contribute to individual differences in cognitive f...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25316
更新日期:2020-12-14 00:00:00
abstract::We previously showed that dual-task cost (DTC) on gait speed in people with Parkinson's disease (PD) improved after 6 weeks of the Agility Boot Camp with Cognitive Challenge (ABC-C) exercise program. Since deficits in dual-task gait speed are associated with freezing of gait and gray matter atrophy, here we performed ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25211
更新日期:2021-01-01 00:00:00
abstract::Threatening stimuli have been found to modulate visual processes related to perception and attention. The present functional magnetic resonance imaging (fMRI) study investigated whether threat modulates visual object recognition of man-made and naturally occurring categories of stimuli. Compared with nonthreatening pi...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22039
更新日期:2013-08-01 00:00:00
abstract::The registration of image volumes derived from different imaging modalities such as MRI, PET, SPECT, and CT has been described in numerous studies in which functional and morphological data are combined on the basis of macrostructural information. However, the exact topography of architectural details is defined by mi...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::In this communication, we extended a previously described and validated diffusion tensor imaging (DTI) method for segmenting whole brain cerebrospinal fluid (CSF) and gray and white matter (WM) tissue to provide regional volume and DTI metrics of WM tract and cortical and subcortical gray matter. This DTI-based region...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21004
更新日期:2011-01-01 00:00:00
abstract::We systematically investigated the effects of cathodal and anodal Transcranial Direct Current Stimulation (CtDCS, AtDCS) on the electric activity of primary motor cortex during a motor task. High-density electroencephalography was used to define the spatial diffusion of tDCS after effects. Ten healthy subjects perform...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22322
更新日期:2014-05-01 00:00:00
abstract::Previous studies have shown that white matter in the deaf brain changes due to hearing loss. However, how white-matter development is influenced by early hearing experience of deaf people is still unknown. Using diffusion tensor imaging and tract-based spatial statistics, we compared white-matter structures among thre...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21215
更新日期:2012-02-01 00:00:00
abstract::Pramipexole is widely prescribed to treat Parkinson's disease. It has been found to cause impulse control disorders such as pathological gambling. To examine how pramipexole modulates the network of reward anticipation, we carried out a pharmacological functional magnetic resonance imaging study with a double-blind, w...
journal_title:Human brain mapping
pub_type: 杂志文章,随机对照试验
doi:10.1002/hbm.21067
更新日期:2011-05-01 00:00:00
abstract::Imagination and creative cognition are often associated with the brain's default network (DN). Recent evidence has also linked cognitive control systems to performance on tasks involving imagination and creativity, with a growing number of studies reporting functional interactions between cognitive control and DN regi...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23884
更新日期:2018-02-01 00:00:00
abstract::Sedation has a graded effect on brain responses to auditory stimuli: perceptual processing persists at sedation levels that attenuate more complex processing. We used fMRI in healthy volunteers sedated with propofol to assess changes in neural responses to spoken stimuli. Volunteers were scanned awake, sedated, and du...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22375
更新日期:2014-07-01 00:00:00
abstract::Extensive efforts are devoted to understand the functional (FC) and structural connections (SC) of the brain. FC is usually measured by functional magnetic resonance imaging (fMRI), and conceptualized as degree of synchronicity in brain activity between different regions. SC is typically indexed by measures of white m...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23403
更新日期:2017-01-01 00:00:00
abstract::We investigated neural substrates of global/local processing of bilateral hierarchical stimuli using functional magnetic resonance imaging (fMRI). Subjects were presented with two compound letters that were displayed simultaneously in the left and right visual fields, respectively. In a steady-state, block-design para...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20044
更新日期:2004-08-01 00:00:00