Abstract:
:We investigated neural substrates of global/local processing of bilateral hierarchical stimuli using functional magnetic resonance imaging (fMRI). Subjects were presented with two compound letters that were displayed simultaneously in the left and right visual fields, respectively. In a steady-state, block-design paradigm, hemodynamic responses were recorded while subjects detected infrequent global or local targets presented in one hemifield in separate epochs of trials. While behavioural responses were more accurate and faster to global than local targets, attention to the global level of bilateral visual inputs induced stronger activations in the left and right temporal cortex relative to attention to the local level. However, attention to the local level generated stronger activations in bilateral superior parietal cortex compared with attention to the global level. The results suggest that distinct neural substrates in the temporal and parietal cortices are preferentially engaged in the global and local processing of bilateral visual inputs, respectively.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Han S,Jiang Y,Gu Hdoi
10.1002/hbm.20044keywords:
subject
Has Abstractpub_date
2004-08-01 00:00:00pages
321-8issue
4eissn
1065-9471issn
1097-0193journal_volume
22pub_type
杂志文章abstract::Studies of the neural basis of intelligence have focused on comparing brain imaging variables with global scales instead of the cognitive domains integrating these scales or quotients. Here, the relation between mean tract-based fractional anisotropy (mTBFA) and intelligence indices was explored. Deterministic tractog...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24848
更新日期:2020-03-01 00:00:00
abstract::A face-selective neural signal is reliably found in humans with functional MRI and event-related potential (ERP) measures, which provide complementary information about the spatial and temporal properties of the neural response. However, because most neuroimaging studies so far have studied ERP and fMRI face-selective...
journal_title:Human brain mapping
pub_type: 杂志文章,随机对照试验
doi:10.1002/hbm.20952
更新日期:2010-10-01 00:00:00
abstract::The practical use of realistic models in bioelectromagnetism is limited by the time-consuming amount of numerical calculations. We propose a method leading to much higher speed than currently available, and compatible with any kind of numerical methods (boundary elements (BEM), finite elements, finite differences). Il...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.1041
更新日期:2001-09-01 00:00:00
abstract::The cingulum bundle is a white matter fiber bundle in the human brain that is believed to be implicated in various neurological and psychiatric diseases. Subtle disease-related differences in metabolite concentrations in the cingulum tracts that may underlie these diseases may be detected using MR spectroscopic inform...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21302
更新日期:2012-07-01 00:00:00
abstract::Low socioeconomic status (SES) is associated with a higher probability of multiple exposures (e.g., neighborhood violence, poor nutrition, housing instability, air pollution, and insensitive caregiving) known to affect structural development of subcortical brain regions that subserve threat and reward processing, howe...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24796
更新日期:2020-01-01 00:00:00
abstract::Glucose transporter type I deficiency syndrome (GLUT1DS) is an encephalopathic disorder due to a chronic insufficient transport of glucose into the brain. PET studies in GLUT1DS documented a widespread cortico-thalamic hypometabolism and a signal increase in the basal ganglia, regardless of age and clinical phenotype....
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24815
更新日期:2020-02-01 00:00:00
abstract::We contend that powerful group studies can be conducted using magnetoencephalography (MEG), which can provide useful insights into the approximate distribution of the neural activity detected with MEG without requiring magnetic resonance imaging (MRI) for each participant. Instead, a participant's MRI is approximated ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10133
更新日期:2003-11-01 00:00:00
abstract::Despite a growing number of reports about alterations in intrinsic/resting brain activity observed in patients with psychotic disorders, their relevance to well-established cognitive control deficits in this patient group is not well understood. Totally 88 clinically stabilized patients with a psychotic disorder and 5...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24362
更新日期:2019-01-01 00:00:00
abstract::A diffusion-weighted (DW) template in a standard coordinate system is often necessary for the analysis of white matter (WM) structures using DW images. Although several DW templates have been constructed in the ICBM-152 space, a template for diffusion spectrum imaging (DSI) is still lacking. In this study, we develope...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22860
更新日期:2015-09-01 00:00:00
abstract::Resection of the seizure generating tissue can be highly beneficial in patients with drug-resistant epilepsy. However, only about half of all patients undergoing surgery get permanently and completely seizure free. Investigating the dependences between intracranial EEG signals adds a multivariate perspective largely u...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24816
更新日期:2020-02-01 00:00:00
abstract::Before considering a given fMRI paradigm as a valid clinical tool, one should first assess the reliability of functional responses across subjects by establishing a normative database and defining a reference activation map that identifies major brain regions involved in the task at hand. However, the definition of su...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20410
更新日期:2008-04-01 00:00:00
abstract::Most of the previous task functional magnetic resonance imaging (fMRI) studies found abnormalities in distributed brain regions in mild cognitive impairment (MCI) and Alzheimer's disease (AD), and few studies investigated the brain network dysfunction from the system level. In this meta-analysis, we aimed to examine b...
journal_title:Human brain mapping
pub_type: 杂志文章,meta分析,评审
doi:10.1002/hbm.22689
更新日期:2015-03-01 00:00:00
abstract::We present a new technique for segmentation of skull and scalp in T(1)-weighted magnetic resonance images (MRIs) of the human head. Our method uses mathematical morphological operations to generate realistic models of the skull, scalp, and brain that are suitable for electroencephalography (EEG) and magnetoencephalogr...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20159
更新日期:2005-12-01 00:00:00
abstract::We demonstrate that multivoxel pattern analysis can be used to decode place-related information in fMRI. Subjects performed a working memory version of the Morris water maze task in a virtual environment with a single wall cue. The voxel data that corresponds to when subjects were located at the goal was extracted for...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20873
更新日期:2010-03-01 00:00:00
abstract::Variability quenching is a widespread neural phenomenon in which trial-to-trial variability (TTV) of neural activity is reduced by repeated presentations of a sensory stimulus. However, its neural mechanism and functional significance remain poorly understood. Recurrent network dynamics are suggested as a candidate me...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24304
更新日期:2018-11-01 00:00:00
abstract::Action observation leads to the automatic activation of the corresponding motor representation in the observer through "mirror-matching." This constitutes a "shared representational system," which is thought to subserve social understanding by motor simulation. However, it is unclear how these shared representations c...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20800
更新日期:2009-11-01 00:00:00
abstract::Navigated transcranial magnetic stimulation (TMS) can be used to stimulate functional cortical areas at precise anatomical location to induce measurable responses. The stimulation has commonly been focused on anatomically predefined motor areas: TMS of that area elicits a measurable muscle response, the motor evoked p...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20942
更新日期:2010-08-01 00:00:00
abstract::Simultaneous electroencephalogram/functional magnetic resonance imaging (EEG-fMRI) during interictal epileptiform discharges can result in positive (activation) and negative (deactivation) changes in the blood oxygenation level-dependent (BOLD) signal. Activation probably reflects increased neuronal activity and energ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20193
更新日期:2006-06-01 00:00:00
abstract::In functional magnetic resonance imaging (fMRI) research one is typically interested in neural activity. However, the blood-oxygenation level-dependent (BOLD) signal is a composite of both neural and vascular activity. As factors such as age or medication may alter vascular function, it is essential to account for cha...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22768
更新日期:2015-06-01 00:00:00
abstract::The framework of assimilation and accommodation has been proposed to explain the brain mechanisms supporting second language reading acquisition (Perfetti et al. [2007]: Bilingual Lang Cogn 10:131). Assimilation refers to using the procedures of the native language network in the acquisition of a new writing system, w...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22904
更新日期:2015-10-01 00:00:00
abstract::Numerous studies suggest that interhemispheric inhibition-relayed via the corpus callosum-plays an important role in unilateral hand motions. Interestingly, transcallosal inhibition appears to be indicative of a strong laterality effect, where generally the dominant hemisphere exerts inhibition on the nondominant one....
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22060
更新日期:2013-09-01 00:00:00
abstract::What basic visual structures underlie human face detection and how can we extract such structures directly from the amplitude of neural responses elicited by face processing? Here, we address these issues by investigating an extension of noise-based image classification to BOLD responses recorded in high-level visual ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22128
更新日期:2013-11-01 00:00:00
abstract::The functional role of the left ventral occipito-temporal cortex (vOT) in visual word processing has been studied extensively. A prominent observation is higher activation for unfamiliar but pronounceable letter strings compared to regular words in this region. Some functional accounts have interpreted this finding as...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22281
更新日期:2014-04-01 00:00:00
abstract::Early and accurate mild cognitive impairment (MCI) detection within a heterogeneous, nonclinical population is needed to improve care for persons at risk of developing dementia. Magnetic resonance imaging (MRI)-based classification may aid early diagnosis of MCI, but has only been applied within clinical cohorts. We a...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24554
更新日期:2019-06-15 00:00:00
abstract::Apathy, common in neurological disorders, is defined as disinterest and loss of motivation, with a reduction in self-initiated activity. Research in diseased populations has shown that apathy is associated with variations in the volume of brain regions such as the anterior cingulate and the frontal lobes. The goal of ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22225
更新日期:2014-03-01 00:00:00
abstract::Fine surface texture is best discriminated by touch, in contrast to macro geometric features like shape. We used functional magnetic resonance imaging and a delayed match-to-sample task to investigate the neural substrate for working memory of tactile surface texture. Blindfolded right-handed males encoded the texture...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21500
更新日期:2013-05-01 00:00:00
abstract::Rasagiline is a monoamine oxidase type B inhibitor that possesses no amphetamine-like properties, and provides symptomatic relief in early and late stages of Parkinson's disease (PD). Data in animal models of PD suggest that chronic administration of rasagiline is associated with structural changes in the substantia n...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23213
更新日期:2016-08-01 00:00:00
abstract::Investigations of the neural correlates of face recognition have typically used old/new paradigms where subjects learn to recognize new faces or identify famous faces. Familiar faces, however, include one's own face, partner's and parents' faces. Using event-related fMRI, we examined the neural correlates of these per...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20646
更新日期:2009-07-01 00:00:00
abstract::Recent theories of selective attention assume that the more attention is required by a task, the earlier are irrelevant stimuli filtered during perceptual processing. Previous functional MRI studies have demonstrated that primary visual cortex (V1) activation by peripheral distractors is reduced by higher task difficu...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20636
更新日期:2009-05-01 00:00:00
abstract::An increasing amount of studies apply repetetive transcranial magnetic stimulation (rTMS) to treat chronic tinnitus, yet the neurophysiological impacts have remained largely obscure. Several studies show that endogenous brain rhythms may be enhanced via diverse brain stimulation techniques applying rhythmic stimulatio...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22152
更新日期:2014-01-01 00:00:00