Neural correlates of apathy revealed by lesion mapping in participants with traumatic brain injuries.

abstract：:Demyelination and axonal damage are pathologic hallmarks of multiple sclerosis (MS), leading to loss of neuronal synchronization, functional disconnection amongst brain relays, and clinical sequelae. To investigate these properties, the primary component of the sensorimotor network was analyzed in mildly disabled Rela...

journal_title：Human brain mapping

authors： Dell'Acqua ML,Landi D,Zito G,Zappasodi F,Lupoi D,Rossini PM,Filippi MM,Tecchio F

更新日期：2010-10-01 00:00:00

abstract：:Degeneration of the corpus callosum (CC) is evident in the pathogenesis of Alzheimer's disease (AD). However, the correlation of microstructural damage in the CC on the cognitive performance of patients with amnestic mild cognitive impairment (aMCI) and AD dementia is undetermined. We enrolled 26 normal controls, 24 p...

journal_title：Human brain mapping

authors： Wang PN,Chou KH,Chang NJ,Lin KN,Chen WT,Lan GY,Lin CP,Lirng JF

更新日期：2014-04-01 00:00:00

abstract：:We previously showed that dual-task cost (DTC) on gait speed in people with Parkinson's disease (PD) improved after 6 weeks of the Agility Boot Camp with Cognitive Challenge (ABC-C) exercise program. Since deficits in dual-task gait speed are associated with freezing of gait and gray matter atrophy, here we performed ...

journal_title：Human brain mapping

authors： Silva-Batista C,Ragothaman A,Mancini M,Carlson-Kuhta P,Harker G,Jung SH,Nutt JG,Fair DA,Horak FB,Miranda-Domínguez O

更新日期：2021-01-01 00:00:00

abstract：:Neural dynamics leading to conscious sensory perception have remained enigmatic in despite of large interest. Human functional magnetic resonance imaging (fMRI) studies have revealed that a co-activation of sensory and frontoparietal areas is crucial for conscious sensory perception in the several second time-scale of...

journal_title：Human brain mapping

authors： Hirvonen J,Palva S

更新日期：2016-01-01 00:00:00

abstract：:The nuclei of the human amygdala remain difficult to distinguish in individual subject structural magnetic resonance images. However, interpretation of the amygdala's role in whole brain networks requires accurate localization of functional activity to a particular nucleus or subgroup of nuclei. To address this, high ...

journal_title：Human brain mapping

authors： Tyszka JM,Pauli WM

更新日期：2016-11-01 00:00:00

abstract：:We used emotional expectancy to study attentional modulation in the processing of emotional stimuli. During functional magnetic resonance imaging (fMRI), volunteers saw emotional and neutral expectancy cues signaling the subsequent presentation of corresponding emotional or neutral pictorial stimuli. As a control, emo...

journal_title：Human brain mapping

authors： Bermpohl F,Pascual-Leone A,Amedi A,Merabet LB,Fregni F,Gaab N,Alsop D,Schlaug G,Northoff G

更新日期：2006-08-01 00:00:00

abstract：:Although much has been learned about the functional organization of the human brain through lesion-deficit analysis, the variety of statistical and image-processing methods developed for this purpose precludes a closed-form analysis of the statistical power of these systems. Therefore, we developed a lesion-deficit si...

journal_title：Human brain mapping

authors： Megalooikonomou V,Davatzikos C,Herskovits EH

更新日期：2000-06-01 00:00:00

abstract：:Developmental dyslexia affects 40-60% of children with a familial risk (FHD+) compared to a general prevalence of 5-10%. Despite the increased risk, about half of FHD+ children develop typical reading abilities (FHD+Typical). Yet the underlying neural characteristics of favorable reading outcomes in at-risk children r...

journal_title：Human brain mapping

authors： Yu X,Zuk J,Perdue MV,Ozernov-Palchik O,Raney T,Beach SD,Norton ES,Ou Y,Gabrieli JDE,Gaab N

更新日期：2020-07-01 00:00:00

abstract：:Dysfunctions in prefrontal cortical networks are thought to underlie working memory (WM) impairments consistently observed in both subjects with bipolar disorder and schizophrenia. It remains unclear, however, whether patterns of WM-related hemodynamic responses are similar in bipolar and schizophrenia subjects compar...

journal_title：Human brain mapping

authors： Hamilton LS,Altshuler LL,Townsend J,Bookheimer SY,Phillips OR,Fischer J,Woods RP,Mazziotta JC,Toga AW,Nuechterlein KH,Narr KL

更新日期：2009-12-01 00:00:00

abstract：:Migraine sufferers with aura often report photosensitivity and visual discomfort outside of attacks and many consider bright or flickering light an attack-precipitating factor. The nature of this visual hypersensitivity and its relation to the underlying pathophysiology of the migraine aura is unknown. Using fMRI meas...

journal_title：Human brain mapping

authors： Hougaard A,Amin FM,Hoffmann MB,Rostrup E,Larsson HB,Asghar MS,Larsen VA,Olesen J,Ashina M

更新日期：2014-06-01 00:00:00

abstract：:In previous work (Penny et al., [2005]: Neuroimage 24:350-362) we have developed a spatially regularised General Linear Model for the analysis of functional magnetic resonance imaging data that allows for the characterisation of regionally specific effects using Posterior Probability Maps (PPMs). In this paper we show...

journal_title：Human brain mapping

authors： Penny W,Flandin G,Trujillo-Barreto N

更新日期：2007-04-01 00:00:00

abstract：:Mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD) are common among recent military veterans and involve substantial symptom overlap, making clinical distinction and effective intervention difficult. Emerging evidence of cerebral white matter abnormalities associated with mTBI may provide a b...

journal_title：Human brain mapping

authors： Davenport ND,Lim KO,Sponheim SR

更新日期：2015-03-01 00:00:00

abstract：:It remains unclear whether and to what extent working memory (WM) temporal subprocesses (i.e., encoding, maintenance, and retrieval) involve shared or distinct intrinsic networks. To address this issue, I constructed a model of intrinsic network contributions to different WM phases and then evaluated the validity of t...

journal_title：Human brain mapping

authors： Kim H

更新日期：2019-12-01 00:00:00

abstract：:The control system in human brain generally exerts the goal-directed regulation on a variety of mental processes. To deal with different control demands, these brain areas of the control system, especially the dorsolateral prefrontal cortex (DLPFC), may be flexibly recruited across different tasks. However, few studie...

journal_title：Human brain mapping

authors： Chen Z,Zhao X,Fan J,Chen A

更新日期：2018-12-01 00:00:00

abstract：:The brain seeks to combine related inputs from different senses (e.g., hearing and vision), via multisensory integration. Temporal information can indicate whether stimuli in different senses are related or not. A recent human fMRI study (Noesselt et al. [2007]: J Neurosci 27:11431-11441) used auditory and visual trai...

journal_title：Human brain mapping

authors： Marchant JL,Ruff CC,Driver J

更新日期：2012-05-01 00:00:00

abstract：:Patients with epilepsy are often able to predict seizure occurrence subsequent to an acute stress experience. However, neuroimaging investigations into the neural basis of this relationship or the potential influence of perceived life stress are limited. The current study assessed the relationship between perceived st...

journal_title：Human brain mapping

authors： Goodman AM,Allendorfer JB,Heyse H,Szaflarski BA,Eliassen JC,Nelson EB,Storrs JM,Szaflarski JP

更新日期：2019-08-15 00:00:00

abstract：:Standardized psychometric tests are sophisticated, well-developed, and consequential instruments; test outcomes are taken as facts about people that impact their lives in important ways. As part of an initial demonstration that human brain mapping techniques can add converging neural-level evidence to understanding st...

journal_title：Human brain mapping

authors： Rubin DC,Li D,Hall SA,Kragel PA,Berntsen D

更新日期：2017-11-01 00:00:00

abstract：:Mounting evidence indicates that serum cholesterol and other risk factors for cardiovascular disease intensify normative trajectories of age-related cognitive decline. However, the neural mechanisms by which this occurs remain largely unknown. To understand the impact of cholesterol on brain networks, we applied graph...

journal_title：Human brain mapping

authors： Spielberg JM,Sadeh N,Leritz EC,McGlinchey RE,Milberg WP,Hayes JP,Salat DH

更新日期：2017-06-01 00:00:00

abstract：:From birth to 5 years of age, brain structure matures and evolves alongside emerging cognitive and behavioral abilities. In relating concurrent cognitive functioning and measures of brain structure, a major challenge that has impeded prior investigation of their time-dynamic relationships is the sparse and irregular n...

journal_title：Human brain mapping

authors： Dai X,Hadjipantelis P,Wang JL,Deoni SCL,Müller HG

更新日期：2019-10-01 00:00:00

abstract：:Previous studies have demonstrated that the right ventrolateral prefrontal cortex (RVLPFC) is crucially involved in downregulating physical and social pain. However, it remains unclear whether the RVLPFC is more specific to either physical or social pain. The present study compares the role of RVLPFC in emotion regula...

journal_title：Human brain mapping

authors： He Z,Zhao J,Shen J,Muhlert N,Elliott R,Zhang D

更新日期：2020-04-01 00:00:00

abstract：:Fine surface texture is best discriminated by touch, in contrast to macro geometric features like shape. We used functional magnetic resonance imaging and a delayed match-to-sample task to investigate the neural substrate for working memory of tactile surface texture. Blindfolded right-handed males encoded the texture...

journal_title：Human brain mapping

authors： Kaas AL,van Mier H,Visser M,Goebel R

更新日期：2013-05-01 00:00:00

abstract：:Although imbalanced functional integration has been increasingly reported in major depressive disorder (MDD), there still lacks a general framework to characterize common characteristic and origin shared by the integrative disturbances. Here we examined spatial selectivity, temporal uniqueness, metabolic basis, and th...

journal_title：Human brain mapping

authors： Sheng J,Shen Y,Qin Y,Zhang L,Jiang B,Li Y,Xu L,Chen W,Wang J

更新日期：2018-05-01 00:00:00

abstract：:This study evaluated the neural basis of verbal working memory (WM) function in a group of 20 children and adolescents with fetal alcohol spectrum disorders (FASDs) and 20 typically developing comparison participants using functional magnetic resonance imaging (fMRI). Both groups showed prominent activation in the fro...

journal_title：Human brain mapping

authors： O'Hare ED,Lu LH,Houston SM,Bookheimer SY,Mattson SN,O'Connor MJ,Sowell ER

更新日期：2009-10-01 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder with dysfunction in cortices as well as white matter (WM) tracts. While the changes to WM structure have been extensively investigated in PD, the nature of the functional changes to WM remains unknown. In this study, the regional activity and functional connecti...

journal_title：Human brain mapping

authors： Ji GJ,Ren C,Li Y,Sun J,Liu T,Gao Y,Xue D,Shen L,Cheng W,Zhu C,Tian Y,Hu P,Chen X,Wang K

更新日期：2019-03-01 00:00:00

abstract：:Mathematical word problems are ubiquitous and standard for teaching and evaluating generalization of mathematical knowledge for real-world contexts. It is therefore concerning that the neural mechanisms of word problem solving are not well understood, as these insights represent strong potential for improving educatio...

journal_title：Human brain mapping

authors： Chang TT,Lung TC,Ng CT,Metcalfe AWS

更新日期：2019-04-15 00:00:00

abstract：:There has been a recent call for longitudinal imaging studies to better characterize the time course of physiological recovery following sport-related concussion (SRC) and its relationship with clinical recovery. To address this, we evaluated changes to resting-state functional connectivity (rs-FC) of the whole-brain ...

journal_title：Human brain mapping

authors： Kaushal M,España LY,Nencka AS,Wang Y,Nelson LD,McCrea MA,Meier TB

更新日期：2019-03-01 00:00:00

abstract：:Research using the Stop Signal Task employing an adaptive algorithm to accommodate individual differences often report inferior performance on the task in individuals with ADHD, OCD, and substance use disorders compared to non-clinical controls. Furthermore, individuals with deficits in inhibitory control tend to show...

journal_title：Human brain mapping

authors： D'Alberto N,Chaarani B,Orr CA,Spechler PA,Albaugh MD,Allgaier N,Wonnell A,Banaschewski T,Bokde ALW,Bromberg U,Büchel C,Quinlan EB,Conrod PJ,Desrivières S,Flor H,Fröhner JH,Frouin V,Gowland P,Heinz A,Itterman B,Mar

更新日期：2018-08-01 00:00:00

abstract：:The spatial organization of nonlinear interactions between different brain regions during the first NREM sleep stage is investigated. This is achieved via consideration of four bipolar electrode derivations, Fp1F3, Fp2F4, O1P3, O2P4, which are used to compare anterior and posterior interhemispheric interactions and le...

journal_title：Human brain mapping

authors： Terry JR,Anderson C,Horne JA

更新日期：2004-10-01 00:00:00

abstract：:Auditory steady-state responses (ASSRs) are evoked brain responses to modulated or repetitive acoustic stimuli. Investigating the underlying neural generators of ASSRs is important to gain in-depth insight into the mechanisms of auditory temporal processing. The aim of this study is to reconstruct an extensive range o...

journal_title：Human brain mapping

authors： Farahani ED,Wouters J,van Wieringen A

更新日期：2021-02-15 00:00:00

abstract：:There is good evidence from animal studies for segregation in the processing of non-nociceptive and nociceptive information within the trigeminal brainstem sensory nuclear complex. However, it remains unknown whether a similar segregation occurs in humans, and a recent tract tracing study suggests that this segregatio...

journal_title：Human brain mapping

authors： Nash PG,Macefield VG,Klineberg IJ,Murray GM,Henderson LA

更新日期：2009-11-01 00:00:00