Neural activations at the junction of the inferior frontal sulcus and the inferior precentral sulcus: interindividual variability, reliability, and association with sulcal morphology.

Abstract:

:The sulcal morphology of the human frontal lobe is highly variable. Although the structural images usually acquired in functional magnetic resonance imaging studies provide information about this interindividual variability, this information is only rarely used to relate structure and function. Here, we investigated the spatial relationship between posterior frontolateral activations in a task-switching paradigm and the junction of the inferior frontal sulcus and the inferior precentral sulcus (inferior frontal junction, IFJ) on an individual-subject basis. Results show that, although variable in terms of stereotaxic coordinates, the posterior frontolateral activations observed in task-switching are consistently and reliably located at the IFJ in the brains of individual participants. The IFJ shares such consistent localization with other nonprimary areas as motion-sensitive area V5/MT and the frontal eye field. Building on tension-based models of morphogenesis, this structure-function correspondence might indicate that the cytoarchitectonic area underlying activations of the IFJ develops at early stages of cortical folding.

journal_name

Hum Brain Mapp

journal_title

Human brain mapping

authors

Derrfuss J,Brass M,von Cramon DY,Lohmann G,Amunts K

doi

10.1002/hbm.20501

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

299-311

issue

1

eissn

1065-9471

issn

1097-0193

journal_volume

30

pub_type

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