Abstract：
PURPOSE:To investigate the amount of intraocular pressure (IOP) asymmetry in a large group of ethnically diverse patients with and without glaucoma, and to delineate the risk for glaucoma which increasing amounts of IOP asymmetry confer upon the patient. PATIENTS AND METHODS:Collaborative retrospective study of 326 glaucoma patients and 326 controls. Former Wills Eye Institute fellows collected single pre-treatment measurements of IOP on patients diagnosed as having definite glaucoma based on characteristic optic nerve damage and confirmatory visual field damage. Patients with a normal eye examination who had normal-appearing optic discs and no apparent glaucoma, or who had a normal eye examination in association with refractive error or cataract, were used as controls. RESULTS:Intraocular pressure asymmetry is a significant risk factor for having glaucoma (odds ratio, 2.14; 95% confidence interval, 1.86-2.47; P<0.001). Absence of IOP asymmetry between the fellow eyes is associated with a 1% probability of having glaucoma. A difference of 3 mm Hg is associated with a 6% probability of having glaucoma, and a difference of >6 mm Hg with a 57% probability of having glaucoma. The association between IOP asymmetry and glaucoma status is significant for subjects with both elevated IOP (P=0.014) and statistically normal IOP (maximum IOP ≤ 21 mm Hg; P<0.001). CONCLUSIONS:Inter-eye asymmetry of IOP is a common finding in patients with glaucoma. There is a direct relationship between the amount of IOP asymmetry between the fellow eyes and the likelihood of having glaucoma.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Williams AL,Gatla S,Leiby BE,Fahmy I,Biswas A,de Barros DM,Ramakrishnan R,Bhardwaj S,Wright C,Dubey S,Lynch JF,Bayer A,Khandelwal R,Ichhpujani P,Gheith M,Siam G,Feldman RM,Henderer JD,Spaeth GLdoi
10.1097/IJG.0b013e318237bfb8subject
Has Abstractpub_date
2013-03-01 00:00:00pages
215-8issue
3eissn
1057-0829issn
1536-481Xjournal_volume
22pub_type
杂志文章abstract：PRECIS:Repeated use of the Micropulse P3 (MP3) probe during micropulse transscleral cyclophotocoagulation is associated with an increase in laser output over time. PURPOSE:The purpose of this study was to examine the laser efficacy of the MP3 probe following repeated use. METHODS:This was an observational study carri...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001277
更新日期：2019-08-01 00:00:00
abstract：PURPOSE:We explored the risk factors for glaucoma blindness among adults aged 40 years and above with primary glaucoma in Nigeria. PARTICIPANTS AND METHODS:A total of 13,591 participants aged 40 years and above were examined in the Nigeria Blindness Survey; 682 (5.02%; 95 CI, 4.60%-5.47%) had glaucoma by ISGEO's crite...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000487
更新日期：2016-10-01 00:00:00
abstract：:To prevent corneal endothelial cell loss, ciliary sulcus tube insertion is preferred for the pseudophakic eye. However, we sometimes encounter technical difficulties when inserting the tube through the sulcus. Even in cases in which we are able to insert a 23-G needle through the sulcus into the space between the iris...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001602
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:To evaluate aqueous levels of vascular endothelial growth factor (VEGF) and endothelin-1 (ET-1) in patients with branch retinal vein occlusion (BRVO) with and without normal tension glaucoma (NTG), and to assess the therapeutic efficacy of intravitreal bevacizumab (IVB) in these patients. METHODS:Sixteen eyes ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3182312047
更新日期：2013-02-01 00:00:00
abstract：PURPOSE:To investigate the frequency of choroidal microvasculature dropout (CMvD) in healthy myopic eyes in comparison with that of myopic open-angle glaucoma (OAG) eyes and determine whether myopia is independently associated with CMvD. PATIENTS AND METHODS:Choroidal layer microvasculature images were obtained using ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000859
更新日期：2018-02-01 00:00:00
abstract：PURPOSE:To evaluate the effect of a single treatment of contact diode laser transscleral cyclophotocoagulation (TSCP) on intraocular pressure (IOP) in patients with refractory glaucoma and perform a historical meta-analysis of the relationship between successful IOP control and various laser parameters. METHODS:Clinic...
journal_title：Journal of glaucoma
pub_type： 杂志文章,meta分析
doi：10.1097/00061198-200208000-00009
更新日期：2002-08-01 00:00:00
abstract：PURPOSE:This study determined the rate of response to latanoprost compared with timolol in patients with glaucoma or ocular hypertension, whether some patients convert from non-responders to responders after more prolonged therapy, and whether this conversion represents a delayed response or random fluctuation. METHOD...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00061198-200312000-00004
更新日期：2003-12-01 00:00:00
abstract：PURPOSE:To determine whether early intraocular pressure (IOP) after mitomycin-C (MMC) augmented trabeculectomy has any predictive value for intermediate IOP outcome. METHODS:Retrospective case note review. All cases of trabeculectomy using MMC augmentation and at least 1-year follow-up during the study period were inc...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31805d014a
更新日期：2007-10-01 00:00:00
abstract：PURPOSE:Evaluate the long-term results of the Ahmed glaucoma valve (AGV) surgery in association with bevacizumab (Avastin) in neovascular glaucoma (NVG) patients. DESIGN AND METHODS:This retrospective institutional study reviewed 39 eyes of 34 patients with NVG who underwent AGV implantation. The intravitreal bevacizu...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000234
更新日期：2015-06-01 00:00:00
abstract：PRECIS:Micropulse trans-scleral cyclophotocoagulation is only moderately effective in lowering intraocular pressure and useful as an adjunct procedure to other glaucoma surgeries. There was a small risk of loss of vision, prolonged hypotony and phthisis bulbi. AIMS:To determine the efficacy and safety of a single micr...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001729
更新日期：2020-10-29 00:00:00
abstract：PURPOSE:To analyze oxidative stress in primary open-angle glaucoma (POAG). MATERIAL AND METHODS:A case-control study including 90 eyes of 90 patients who needed antiglaucomatous surgery in the course of POAG (glaucoma group, n=50) and from patients who were operated of nonpathologic cataracts (cataract group, n=40). F...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31815c3a7f
更新日期：2008-06-01 00:00:00
abstract：PURPOSE:To evaluate the safety and efficacy of Ahmed Glaucoma Valve implantation (AGVI) for the management of neovascular glaucoma (NVG) associated with proliferative diabetic retinopathy (PDR) in the vitrectomized eyes. PATIENTS AND METHODS:We reviewed the medical records of patients with NVG associated with PDR who ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181f3eb06
更新日期：2011-09-01 00:00:00
abstract：PURPOSE:To report 3-year results evaluating the effect on safety and efficacy of canaloplasty to treat open-angle glaucoma when combined with cataract surgery. PATIENTS AND METHODS:This was a retrospective subset analysis of a prospective, international, multicenter study evaluating 133 eyes of 133 adult, open-angle g...
journal_title：Journal of glaucoma
pub_type： 杂志文章,多中心研究
doi：10.1097/IJG.0b013e318285ff13
更新日期：2015-03-01 00:00:00
abstract：PURPOSE:To evaluate the incidence of glaucoma and elevation of intraocular pressure (IOP) in patients with inflammatory eye disease. METHODS:Retrospective review of medical records of 391 consecutive patients with uveitis attending a uveitis clinic of an academic Department of Ophthalmology from January 1999 to August...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/01.ijg.0000146391.77618.d0
更新日期：2004-12-01 00:00:00
abstract：PURPOSE:The aims of this study were to observe the changes in the demand for prescriptions of ocular hypertensive drug (OHD) after cataract surgery, to investigate patterns of change in the required OHD amount in open-angle glaucoma (OAG) and angle-closure glaucoma (ACG) cases, and to determine the associated factors r...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000969
更新日期：2018-07-01 00:00:00
abstract：:PRéCIS:: In this study, we report clinical results after implantation of an adjustable glaucoma drainage device. The intraocular pressure (IOP) profile was efficiently controlled postoperatively as the resistance to aqueous humor outflow was finely adjusted. PURPOSE:The main purpose of this study was to evaluate the ...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1097/IJG.0000000000001209
更新日期：2019-05-01 00:00:00
abstract：OBJECTIVES:This study was conducted to evaluate the effect of long-term intraocular pressure reduction with timolol on the incidence of glaucomatous visual field defects and optic nerve cupping in individuals with ocular hypertension and to compare this incidence with that of a similar group on no treatment. ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：PURPOSE:To determine the effect of cataract extraction on the glaucoma progression index (GPI) in glaucoma patients with coexisting cataract. PATIENTS AND METHODS:This is a retrospective noncomparative study. Consecutive eligible patients with glaucoma who underwent phacoemulsification alone or in combination with aug...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181b21fb9
更新日期：2010-04-01 00:00:00
abstract：PURPOSE:The authors identify any diurnal intraocular pressure (IOP) variation in healthy Cayo Santiago macaques, as well as Cayo Santiago macaques with normotensive and hypertensive primary open-angle glaucoma (POAG), to further evaluate their potential value as a model for human POAG. METHODS:Twenty-four monkeys (eig...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：PURPOSE:Evaluating the use of Indomethacin, Dexamethasone, and no anti-inflammatory treatment immediately after selective laser trabeculoplasty (SLT). MATERIALS AND METHODS:Prospective randomized clinical trial of 132 eyes. Both eyes of the patient underwent SLT. One of the eyes was treated with Indomethacin 0.1% or D...
journal_title：Journal of glaucoma
pub_type： 杂志文章,随机对照试验
doi：10.1097/IJG.0000000000000522
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:We aimed to evaluate the ability of new psychophysical discrimination tests, based on readily available hardware, to probe motion, achromatic, and chromatic contrast sensitivity, across the natural history of glaucoma. We assessed the sensitivity of these tests to detect functional damage at ocular hypertension...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000226
更新日期：2016-06-01 00:00:00
abstract：INTRODUCTION:We present a case of persistent aqueous misdirection, after Ahmed glaucoma valve surgery, despite undergoing an anterior vitrectomy with hyaloido-zonulectomy and iridectomy. CASE REPORT:A 73-year-old female patient, 4 months after phacotrabeculectomy, was referred with persistent high intraocular pressure...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000877
更新日期：2018-04-01 00:00:00
abstract：:A 54-year-old woman who presented with photopsia was found to have elevated intraocular pressure in both eyes and optic disc cupping in the right eye. Angle infiltration was noted on gonioscopy. She was previously been diagnosed with metastatic breast cancer. This case report describes a rare case of glaucoma as a com...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001445
更新日期：2020-03-01 00:00:00
abstract：PURPOSE:To determine whether a structure-function model developed for normal age-related losses of retinal ganglion cells also models the retinal ganglion cell losses in glaucomatous optic neuropathy. METHODS:The model to relate age-related loss of retinal nerve fiber layer thickness and reduced sensitivity for standa...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31820bcfbe
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:The objective of this article was to study longitudinal changes in bleb morphology (presence of microcysts and bleb height and vascularity) in subjects enrolled in the Singapore 5-Fluorouracil (5-FU) trabeculectomy study. STUDY DESIGN:Retrospective subgroup analysis of a randomized controlled trial. MATERIA...
journal_title：Journal of glaucoma
pub_type： 杂志文章,随机对照试验
doi：10.1097/IJG.0000000000000967
更新日期：2018-07-01 00:00:00
abstract：PURPOSE:To determine the efficacy of selective laser trabeculoplasty (SLT) in a tertiary care referral center. PATIENTS AND METHODS:In this retrospective study of selective laser trabeculoplasty performed by five physicians, 94 eyes from 94 patients were included. A majority (83/92, 90%) underwent 180 degrees selectiv...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/01.ijg.0000176939.43681.c2
更新日期：2005-10-01 00:00:00
abstract：PURPOSE:The purpose of this study was to determine the proportion of patients in the US population who are receiving long-term intraocular pressure (IOP)-lowering medication, but, deny having a diagnosis of glaucoma or elevated IOP. MATERIALS AND METHODS:The National Health and Nutrition Examination Survey (NHANES) is...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001035
更新日期：2018-11-01 00:00:00
abstract：PURPOSE:The purpose of this study was to compare intraocular pressure measurements obtained with XPERT, an upgraded model of the noncontact tonometer, with those from Goldmann applanation tonometry. METHODS:An average of three intraocular pressure measurements, generated by the XPERT, was compared with a single readin...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：PURPOSE:To compare the efficacy and tolerability of latanoprost or brimonidine in patients with elevated intraocular pressure (IOP). MATERIALS AND METHODS:This prospective, randomized, masked-evaluator, parallel-group, multicenter study in the United States included patients with primary open angle glaucoma or ocular ...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1097/01.ijg.0000151881.99607.4e
更新日期：2005-04-01 00:00:00
abstract：PURPOSE:To determine the impact of 8 multicenter randomized clinical trials (RCTs) on glaucoma practice. METHODS:An electronic survey was distributed to the members of the American Glaucoma Society (AGS). Each participant was asked 2 study-specific questions and 1 standard question common to all 8 RCTs assessing the s...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e318295200b
更新日期：2015-01-01 00:00:00
