Choroidal Microvasculature Dropout is Not Associated With Myopia, But is Associated With Glaucoma.

Abstract:

PURPOSE:To investigate the frequency of choroidal microvasculature dropout (CMvD) in healthy myopic eyes in comparison with that of myopic open-angle glaucoma (OAG) eyes and determine whether myopia is independently associated with CMvD. PATIENTS AND METHODS:Choroidal layer microvasculature images were obtained using optical coherence tomography angiography in 89 myopic OAG patients and 89 age-matched and refractive error-matched healthy myopic eyes. CMvD was defined as a complete loss of the microvasculature network on the choroidal layer vessel density (VD) map. The frequency of CMvD was compared between myopic OAG and healthy myopic eyes. Hemispheric comparisons of various parameters were performed between CMvD-affected and CMvD-unaffected hemiretina. The association of myopia with the presence and angular circumference of CMvD was evaluated using logistic and linear regression analyses. RESULTS:CMvD was identified in 40 eyes (47.6%) with myopic OAG, whereas no CMvD was found in healthy myopic eyes. Mean hemispheric visual field sensitivity (294.9±321.1 vs. 610.5±387.5, P=0.006), retinal nerve fiber layer thickness (68.9±11.5 vs. 82.5±20.6 μm, P=0.001), and circumpapillary VD (50.5%±7.3% vs. 53.9%±8.8%, P=0.048) were significantly worse in the CMvD-affected hemiretina than in the CMvD-unaffected hemiretina. The presence and angular circumference of CMvD was significantly associated with parameters (visual field mean deviation, retinal nerve fiber layer thickness, and circumpapillary VD; P<0.05) representing glaucoma severity rather than parameters (refractive error and axial length; P>0.05) representing myopic change. CONCLUSIONS:CMvD was observed only in glaucomatous eyes and associated with severity of glaucomatous damage in myopic OAG subjects. The angular circumference of CMvD was significantly related to glaucoma severity.

journal_name

J Glaucoma

journal_title

Journal of glaucoma

authors

Shin JW,Kwon J,Lee J,Kook MS

doi

10.1097/IJG.0000000000000859

subject

Has Abstract

pub_date

2018-02-01 00:00:00

pages

189-196

issue

2

eissn

1057-0829

issn

1536-481X

journal_volume

27

pub_type

杂志文章
  • Outcomes of inferonasal Baerveldt glaucoma drainage implant surgery.

    abstract:PURPOSE:To determine the outcomes of inferonasal Baerveldt glaucoma implant (BGI) surgery. PATIENTS AND METHODS:A retrospective, non-comparative case series of 182 eyes of 182 patients who underwent inferonasal placement of a Baerveldt glaucoma implant. The main outcome measures included intraocular pressure, number o...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,多中心研究

    doi:10.1097/01.ijg.0000195597.30600.27

    authors: Harbick KH,Sidoti PA,Budenz DL,Venkatraman A,Bruther M,Grayson DK,Ko A,Yi GN

    更新日期:2006-02-01 00:00:00

  • Gonioscopy-assisted Transluminal Trabeculotomy in Uveitic Glaucoma Secondary to Juvenile Idiopathic Arthritis.

    abstract::Gonioscopy-assisted transluminal trabeculotomy (GATT) is a minimally invasive ab interno procedure, performed with guidance of an illuminating microcatheter device (iTrack). The pathophysiology of raised intraocular pressure (IOP) in uveitic glaucoma is commonly due to increased resistance at the trabecular meshwork-S...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001641

    authors: Sachdev A,Khalili A,Choi J,Stead RE,Sung VCT

    更新日期:2020-10-01 00:00:00

  • Surgical outcomes of the Baerveldt Glaucoma Implant: differences between surgical techniques in the Rotterdam Eye Hospital.

    abstract:PURPOSE:During the last decades, the Baerveldt Glaucoma Implant (BGI) has proven effective in the surgical treatment of glaucoma. Various surgical procedures have been used for its implantation and these may yield different clinical outcomes and different intraoperative and postoperative complications. We evaluated the...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3182447b7c

    authors: Poels MM,Niessen AG,de Waard PW,Lemij HG

    更新日期:2013-06-01 00:00:00

  • Cohort Study of Nonmelanoma Skin Cancer and the Risk of Exfoliation Glaucoma.

    abstract:PRECIS:In a cohort study of 120,307 participants with 25+ years of follow-up, a history of nonmelanoma skin cancer (NMSC) was associated with a 40% higher exfoliation glaucoma (XFG) risk. PURPOSE:The purpose of this study was to evaluate the relationship between NMSC (a marker of ultraviolet radiation exposure) and XF...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001496

    authors: Kang JH,VoPham T,Laden F,Rosner BA,Wirostko B,Ritch R,Wiggs JL,Qureshi A,Nan H,Pasquale LR

    更新日期:2020-06-01 00:00:00

  • Diurnal intraocular pressure curves in healthy rhesus macaques (Macaca mulatta) and rhesus macaques with normotensive and hypertensive primary open-angle glaucoma.

    abstract:PURPOSE:The authors identify any diurnal intraocular pressure (IOP) variation in healthy Cayo Santiago macaques, as well as Cayo Santiago macaques with normotensive and hypertensive primary open-angle glaucoma (POAG), to further evaluate their potential value as a model for human POAG. METHODS:Twenty-four monkeys (eig...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:

    authors: Komaromy AM,Brooks DE,Kubilis PS,Dawson WW,Sapp HL Jr,Nelson G,Collins BR,Sherwood MB

    更新日期:1998-04-01 00:00:00

  • Serum Bile Acids in Patients With Primary Open-angle Glaucoma.

    abstract:PURPOSE:To measure the serum bile acids (SBA) in patients with primary open-angle glaucoma (POAG) and to compare with nonglaucomatous controls. PATIENTS AND METHODS:A hospital-based case control study of 90 patients above the age of 40 years was conducted. Patients with POAG formed the study group and individuals with...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000000993

    authors: Jacob MM,Pai H V,Gnanaharan J,Kamath S

    更新日期:2018-08-01 00:00:00

  • Decreased response of plasma cortisol to intravenous metyrapone in ocular hypertension and primary open-angle glaucoma.

    abstract:PURPOSE:To determine if there is a difference in response to metyrapone, which blocks the conversion of 11-deoxycortisol to cortisol in the adrenal gland between normals and ocular hypertensives (OH) plus primary open-angle glaucomas (POAG) without pigmented angles. METHODS:Intravenous metyrapone was given to 20 norma...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/01.ijg.0000185613.56168.9d

    authors: Schwartz B,Wysocki A,Qi Y

    更新日期:2005-12-01 00:00:00

  • Optic disc hemorrhage in Asian glaucoma patients.

    abstract:PURPOSE:To assess the prevalence of optic disc hemorrhage in Asian patients with established glaucoma using a recently described, highly sensitive detection method. MATERIALS AND METHODS:Patients entering a trial of glaucoma filtering surgery in Southeast Asia (The Singapore 5FU Study) were assessed for the presence o...

    journal_title:Journal of glaucoma

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00061198-200306000-00008

    authors: Gazzard G,Morgan W,Devereux J,Foster P,Oen F,Seah S,Khaw PT,Chew P

    更新日期:2003-06-01 00:00:00

  • Application of the ISNT Rule to Neuroretinal Rim Thickness Determined Using Cirrus HD Optical Coherence Tomography.

    abstract:PURPOSE:The study investigated the applicability of the inferior≥superior≥nasal≥temporal neuroretinal rim thickness (ISNT) rule to rim thickness measured using Cirrus high-definition spectral-domain optical coherence tomography (Cirrus HD-OCT) in healthy eyes and eyes with glaucoma. METHODS:Rim thicknesses of 4 quadra...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000000015

    authors: Hwang YH,Kim YY

    更新日期:2015-09-01 00:00:00

  • Accuracy of Measurements With the iCare HOME Rebound Tonometer.

    abstract:PURPOSE:To evaluate the accuracy of intraocular pressure (IOP) measurements obtained with the newly available iCare HOME (RTHOME) rebound tonometer compared with the iCare ONE (RTONE) tonometer and Goldmann applanation tonometry (GAT), and possible correlation with central corneal thickness (CCT). MATERIALS AND METHOD...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/IJG.0000000000000390

    authors: Termühlen J,Mihailovic N,Alnawaiseh M,Dietlein TS,Rosentreter A

    更新日期:2016-06-01 00:00:00

  • Mitomycin C in higher risk trabeculectomy: a prospective comparison of 0.2- to 0.4-mg/cc doses.

    abstract:PURPOSE:This randomized, masked, prospective study was conducted to compare the outcome of filtering surgery using doses of 0.2 mg/cc or 0.4 mg/cc of mitomycin C (MMC) in eyes that were at higher risk from previous conjunctival incisional surgery. METHODS:Eyes of 50 consecutive patients with primary open-angle, pseudo...

    journal_title:Journal of glaucoma

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Sanders SP,Cantor LB,Dobler AA,Hoop JS

    更新日期:1999-06-01 00:00:00

  • Using Anterior Segment Optical Coherence Tomography (ASOCT) Parameters to Determine Pupillary Block Versus Plateau Iris Configuration.

    abstract::PRéCIS:: The potential parameters for differentiating pupillary block (PB) from plateau iris configuration (PIC) on anterior segment optical coherence tomography (ASOCT) are lens/pupil size parameters and angles. Further study is needed to determine a landmark peripheral to the centroid of the iris. PURPOSE:Investiga...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001664

    authors: Crowell EL,Chuang AZ,Bell NP,Blieden LS,Feldman RM

    更新日期:2020-11-01 00:00:00

  • Risk factors for hyphema after trabeculectomy with mitomycin C.

    abstract:PURPOSE:To determine the risk factors for hyphema after trabeculectomy with mitomycin C (MMC). PATIENTS AND METHODS:In total, 420 patients (420 eyes) with glaucoma who underwent trabeculectomy with MMC between June 1, 2005 and December 31, 2010 at Kumamoto University Hospital, Japan, were retrospectively evaluated. Hy...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3182741c85

    authors: Kojima S,Inatani M,Shobayashi K,Haga A,Inoue T,Tanihara H

    更新日期:2014-06-01 00:00:00

  • Sequential office pressure measurements in the management of glaucoma.

    abstract:PURPOSE:To evaluate the usefulness of day-long sequential office measurements of intraocular pressure (IOP) to make therapeutic decisions in patients with progressive glaucomatous damage despite apparently 'controlled' IOP. METHODS:We reviewed the records of 93 consecutive glaucoma patients (185 eyes) who underwent se...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/01.ijg.0000159125.34241.79

    authors: Collaer N,Zeyen T,Caprioli J

    更新日期:2005-06-01 00:00:00

  • Long-term Glaucoma Treatment with MK-507, Dorzolamide, a Topical Carbonic Anhydrase Inhibitor.

    abstract:PURPOSE:The purpose of this study was to examine the long-term efficacy and safety of dorzolamide (a topical carbonic anhydrase inhibitor, previously known as MK-507) as an ocular hypotensive agent. METHODS:This open-labeled, multicenter, 52-week trial enrolled patients with primary open-angle glaucoma or ocular hyper...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:

    authors: MK-507 Clinical Study Group.

    更新日期:1995-02-01 00:00:00

  • Surgical output and clinic burden of glaucoma in lagos, Nigeria.

    abstract:PURPOSE:To estimate the outpatient clinic burden and surgical workload related to glaucoma in Lagos, Nigeria. METHODS:A multicentre study involving the 2 tertiary eye institutions, 7 secondary eye centers with eye care facilities, and the largest private eye hospital in Lagos state, Nigeria. Data on outpatient departm...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,多中心研究

    doi:10.1097/IJG.0b013e318264cd80

    authors: Adekoya BJ,Onakoya AO,Shah SP,Adepoju FG

    更新日期:2014-01-01 00:00:00

  • Health Economic Analysis in Glaucoma.

    abstract::The pressure on glaucoma services is ever-growing, and policymakers seek robust cost-effectiveness arguments in their decisions around resource allocation. The benefits of glaucoma are in preventing or delaying a future loss of vision and associated quality of life, and this expectation is quantified using a metric ca...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,评审

    doi:10.1097/IJG.0000000000001462

    authors: Park I,Gale J,Skalicky SE

    更新日期:2020-04-01 00:00:00

  • Comparing the Performance of Compass Perimetry With Humphrey Field Analyzer in Eyes With Glaucoma.

    abstract:PURPOSE:To evaluate the reliability indices [fixation losses, false negative response rates (FN) and false positive response rates] and threshold sensitivities obtained from glaucoma patients with a Compass perimeter and to compare the same with the Humphrey field analyzer (HFA). METHODS:In a cross-sectional study, 97...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000000609

    authors: Rao HL,Raveendran S,James V,Dasari S,Palakurthy M,Reddy HB,Pradhan ZS,Rao DA,Puttaiah NK,Devi S

    更新日期:2017-03-01 00:00:00

  • Reoperations for Complications Within 90 Days After Glaucoma Surgery.

    abstract:OBJECTIVE:To describe reoperations in the operating room for complications encountered within 90 days after glaucoma surgery at a single institution over a 2-year period. DESIGN:Retrospective case series. SUBJECTS:Adult patients who have undergone glaucoma surgery including a tube shunt, trabeculectomy with mitomycin...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001484

    authors: Chu CK,Liebmann JM,Cioffi GA,Blumberg DM,Al-Aswad LA

    更新日期:2020-05-01 00:00:00

  • Clinical Efficacy and Safety Outcomes of Micropulse Trans-Scleral Diode Cyclophotocoagulation in Patients with Advanced Glaucoma.

    abstract:PRECIS:Micropulse trans-scleral cyclophotocoagulation is only moderately effective in lowering intraocular pressure and useful as an adjunct procedure to other glaucoma surgeries. There was a small risk of loss of vision, prolonged hypotony and phthisis bulbi. AIMS:To determine the efficacy and safety of a single micr...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001729

    authors: Lim JYE,Cecilia AM,Lim KAD,Sng C,Loon SC,Lun WXK,Chew TKP,Koh TCV

    更新日期:2020-10-29 00:00:00

  • Aqueous humor and plasma levels of vascular endothelial growth factor and nitric oxide in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.

    abstract:PURPOSE:To investigate levels of vascular endothelial growth factor (VEGF) and nitric oxide (NO) in the aqueous humor and plasma of patients with pseudoexfoliation syndrome (PXS) and pseudoexfoliation glaucoma (PXG), compared with controls. METHODS:This prospective study involved 37 patients with PXS, 15 with PXG, and...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3181aae93e

    authors: Borazan M,Karalezli A,Kucukerdonmez C,Bayraktar N,Kulaksizoglu S,Akman A,Akova YA

    更新日期:2010-03-01 00:00:00

  • A randomized clinical trial of selective laser trabeculoplasty versus argon laser trabeculoplasty in patients with pseudoexfoliation.

    abstract:PURPOSE:To evaluate the efficacy of selective laser trabeculoplasty (SLT) versus argon laser trabeculoplasty (ALT) in lowering the intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension secondary to pseudoexfoliation. DESIGN:Multicentered randomized clinical trial. PARTICIPANTS:A total...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/IJG.0b013e31829e55e4

    authors: Kent SS,Hutnik CM,Birt CM,Damji KF,Harasymowycz P,Si F,Hodge W,Pan I,Crichton A

    更新日期:2015-06-01 00:00:00

  • Characteristics of patients who dropout from a glaucoma clinic.

    abstract:PURPOSE:To find the dropout rate and identify the clinical characteristics of patients who drop out in the first year of follow-up from a glaucoma clinic. DESIGN:Descriptive hospital-based study at a tertiary hospital eye department. METHODS:Clinical characteristics of consecutive patients newly diagnosed with glauco...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e31815768b3

    authors: Ashaye AO,Adeoye AO

    更新日期:2008-04-01 00:00:00

  • Trabeculectomy Following Failed Ab Interno Gelatin Microstent: Case Series.

    abstract:PURPOSE:The purpose of this study is to describe the outcomes of mitomycin C (MMC)-augmented trabeculectomy performed following a failed MMC-augmented XEN-45 implantation. DESIGN:Retrospective case series. METHODS:All consecutive cases of MMC-augmented trabeculectomy performed after MMC-augmented XEN-45 in the Glauco...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001000

    authors: Gizzi C,Mohamed-Noriega J,Elkarmouty A,Scott A

    更新日期:2018-10-01 00:00:00

  • Reversal of disc cupping after intraocular pressure reduction in topographic image series.

    abstract:PURPOSE:To identify and characterize 'reversal' of optic nerve cupping following intraocular pressure (IOP) lowering in scanning laser tomography (SLT) longitudinal image series. METHODS:Modification was made to a previously described analytical approach to longitudinally study putatively increased rim area following ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/01.ijg.0000133151.82804.e3

    authors: Tan JC,Hitchings RA

    更新日期:2004-10-01 00:00:00

  • Xen Gel Stent to Resolve Late Hypotony After Glaucoma Drainage Implant Surgery: A Novel Technique.

    abstract:PURPOSE:To describe a new surgical method for treating late profound hypotony in 2 patients with glaucoma drainage implant (GDI). PATIENTS AND METHODS:Two patients, an 85-year-old woman and a 44-year-old woman, presented with choroidal effusions secondary related to chronic hypotony after GDI surgery. A novel techniqu...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001022

    authors: Välimäki J

    更新日期:2018-10-01 00:00:00

  • Peripapillary Vessel Density in Glaucomatous Eyes: Comparison Between Pseudoexfoliation Glaucoma and Primary Open-angle Glaucoma.

    abstract:PURPOSE:The aim of this study was to compare the peripapillary vessel density between eyes with pseudoexfoliation glaucoma (PXG) and eyes with primary open-angle glaucoma (POAG). METHODS:Peripapillary vessel density in the radial peripapillary capillaries was assessed using optical coherence tomography angiography, an...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001062

    authors: Park JH,Yoo C,Girard MJA,Mari JM,Kim YY

    更新日期:2018-11-01 00:00:00

  • Possible association between long anterior lens zonules and plateau iris configuration.

    abstract:PURPOSE:To report plateau iris configuration (PIC) in subjects who have the long anterior zonule (LAZ) clinical trait. METHODS:Two elderly African American males who exhibited LAZ and had partial appositional angle closure persisting after laser iridotomy were imaged with high-resolution ultrasonography to examine for...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e31815c3b04

    authors: Roberts DK,Ayyagari R,Moroi SE

    更新日期:2008-08-01 00:00:00

  • Detection of glaucoma by spectral domain-scanning laser ophthalmoscopy/optical coherence tomography (SD-SLO/OCT) and time domain optical coherence tomography.

    abstract:PURPOSE:To evaluate the relationship between time-domain and spectral domain-scanning laser ophthalmoscopy/optical coherence tomography (SD-SLO/OCT), and to compare the ability of these methods to detect glaucoma. METHODS:Forty-nine glaucoma and 43 healthy participants were imaged by SD-SLO/OCT and Stratus OCT. Bland-...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3181d1d332

    authors: Cho JW,Sung KR,Hong JT,Um TW,Kang SY,Kook MS

    更新日期:2011-01-01 00:00:00

  • Evaluation of Quality of Life in Japanese Glaucoma Patients and its Relationship With Visual Function.

    abstract:PURPOSE:We assessed vision-related quality of life (VR-QOL) in glaucoma patients and examined the relationship between VR-QOL and indices of visual function and subjective symptoms. PATIENTS AND METHODS:Four hundred seventy-two glaucoma patients completed a questionnaire concerning VR-QOL and subjective symptoms of gl...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,多中心研究

    doi:10.1097/IJG.0000000000000221

    authors: Takahashi G,Otori Y,Urashima M,Kuwayama Y,Quality of Life Improvement Committee.

    更新日期:2016-03-01 00:00:00