Abstract:
:Gonioscopy-assisted transluminal trabeculotomy (GATT) is a minimally invasive ab interno procedure, performed with guidance of an illuminating microcatheter device (iTrack). The pathophysiology of raised intraocular pressure (IOP) in uveitic glaucoma is commonly due to increased resistance at the trabecular meshwork-Schlemm canal. By removing this resistance, GATT can potentially control the IOP. In addition, the ab interno approach avoids violating the conjunctiva and reduces the risk of complications including infection, leak, and hypotony. In this series, we discuss 3 uveitic glaucoma cases secondary to juvenile idiopathic arthritis (JIA) that underwent GATT. Case 1 was a 16-year-old phakic female with a preoperative IOP of 25 to 33 mm Hg had 360-degree GATT; her IOP remained stable at 6 to 10 mm Hg over 14 months. Case 2 was a 23-year-old pseudophakic female with a preoperative IOP of 28 to 34 mm Hg had 180-degree GATT; her IOP reduced to 8 mm Hg over 10 months. Case 3 was an 8-year-old aphakic male with a preoperative IOP of 21 to 32 mm Hg had 360-degree GATT; his IOP remained stable at 13 to 15 mm Hg over 21 months. In our limited case series, GATT is very successful in controlling IOP in young uveitic patients with JIA by surgically targeting the underlying pathophysiology.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Sachdev A,Khalili A,Choi J,Stead RE,Sung VCTdoi
10.1097/IJG.0000000000001641subject
Has Abstractpub_date
2020-10-01 00:00:00pages
e116-e119issue
10eissn
1057-0829issn
1536-481Xjournal_volume
29pub_type
杂志文章abstract:PURPOSE:To describe findings and utility of optical coherence tomography angiography (OCTA) in optic nerve head drusen (ONHD). OBSERVATIONS:A 57-year-old white man presented with a decrease in contrast sensitivity of the inferior visual field in both eyes. Clinical examination, visual fields, optical coherence tomogra...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000730
更新日期:2017-09-01 00:00:00
abstract:PURPOSE:To determine the outcomes of inferonasal Baerveldt glaucoma implant (BGI) surgery. PATIENTS AND METHODS:A retrospective, non-comparative case series of 182 eyes of 182 patients who underwent inferonasal placement of a Baerveldt glaucoma implant. The main outcome measures included intraocular pressure, number o...
journal_title:Journal of glaucoma
pub_type: 杂志文章,多中心研究
doi:10.1097/01.ijg.0000195597.30600.27
更新日期:2006-02-01 00:00:00
abstract:PURPOSE:The purpose of this study was to compare intraocular pressure measurements obtained with XPERT, an upgraded model of the noncontact tonometer, with those from Goldmann applanation tonometry. METHODS:An average of three intraocular pressure measurements, generated by the XPERT, was compared with a single readin...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1997-02-01 00:00:00
abstract:PURPOSE:Microvasculature dropout (MvD) is a novel finding seen in optical coherence tomography angiography (OCTA), which is characterized by a localized dehiscence of the choriocapillaris in the parapapillary atrophy area. Disc hemorrhage (DH) is an important factor often associated with the development and especially ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001688
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:Pseudoexfoliation (PEX) syndrome, an age-related, systemic, elastic microfibrillopathy, is characterized by fibrillar-granular deposits in the anterior segment of the eye. Although not representing a true amyloidosis, PEX syndrome shares some features with amyloid disorders, such as Alzheimer disease. It has be...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181ca76c4
更新日期:2010-10-01 00:00:00
abstract:PURPOSE:To measure the change in intraocular pressure (IOP) of the fellow eye after glaucoma surgery in 1 eye. PATIENTS AND METHODS:In this prospective interventional study, 71 patients with primary and secondary glaucoma, undergoing glaucoma surgery in 1 eye were included. The IOP in the fellow eye following glaucoma...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000217
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of selective laser trabeculoplasty (SLT) versus argon laser trabeculoplasty (ALT) in lowering the intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension secondary to pseudoexfoliation. DESIGN:Multicentered randomized clinical trial. PARTICIPANTS:A total...
journal_title:Journal of glaucoma
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/IJG.0b013e31829e55e4
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:To report the use of slit-lamp-adapted optical coherence tomography (SL-OCT) in imaging 2 patients with Descemet membrane detachment following anterior chamber reformation after trabeculectomy. METHODS:Two patients, with leaking and overfiltering blebs, respectively, developed Descemet detachments after reform...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31819c469e
更新日期:2009-12-01 00:00:00
abstract:PURPOSE:The purpose of this study was to perform a comparison of static and dynamic pupillometry measurements in patients with clinically unilateral pseudoexfoliation syndrome (PES) and age-matched controls. METHODS:This prospective cross-sectional study consisted of 38 patients with unilateral PES and 40 control part...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000953
更新日期:2018-06-01 00:00:00
abstract:PRECIS:The VisuALL head-mounted perimetry in normal subjects and glaucoma patients had a moderate to strong correlation with the Humphrey Field Analyzer (HFA). PURPOSE:Visual field testing has a vital role in diagnosing and managing glaucoma. The current clinical practice relies on large, table-based testing units. Th...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001670
更新日期:2021-01-01 00:00:00
abstract::Scanning laser ophthalmoscopy is capable of producing video fluorescein angiograms with high spatial and temporal resolution. Digital image analysis of these angiograms has been used to produce measures of capillary flow velocities in perimacular capillaries. We have recently utilized the same technique to measure flo...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract:PURPOSE:To determine prevalence and associated factors of ocular hypertension in the adult Chinese population. METHODS:The Beijing Eye Study, a population-based prevalence study, included 4439 subjects out of 5324 subjects with an age of 40+ years invited to participate (response rate 83.4%). From the 4439 individuals...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31816b301e
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:To investigate risk factors associated with glaucomatous progression in pseudoexfoliation glaucoma (PXG) patients. PATIENTS AND METHODS:A retrospective observational study with a total of 48 PXG patients and age, sex, and visual field (VF) test mean deviation-matched 48 primary open-angle glaucoma (POAG) patie...
journal_title:Journal of glaucoma
pub_type: 杂志文章,多中心研究
doi:10.1097/IJG.0000000000000791
更新日期:2017-12-01 00:00:00
abstract::A 54-year-old Indian male with a diagnosis of ocular hypertension was started on a prostaglandin analog (PGA) in both eyes to lower intraocular pressure. Six years later, he developed progressively increasing bilateral limbal conjunctival hyperpigmentation. Travoprost was discontinued and replaced with brinzolamide an...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000255
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To evaluate rates of adherence to free follow-up eye exam appointments among participants in the Philadelphia Glaucoma Detection and Treatment Project. PATIENTS AND METHODS:Ophthalmologists and testing equipment were brought directly to participants at risk for glaucoma at 43 community sites in Philadelphia. T...
journal_title:Journal of glaucoma
pub_type: 杂志文章,多中心研究
doi:10.1097/IJG.0000000000000716
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:The study investigated the applicability of the inferior≥superior≥nasal≥temporal neuroretinal rim thickness (ISNT) rule to rim thickness measured using Cirrus high-definition spectral-domain optical coherence tomography (Cirrus HD-OCT) in healthy eyes and eyes with glaucoma. METHODS:Rim thicknesses of 4 quadra...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000015
更新日期:2015-09-01 00:00:00
abstract::The in vivo response to laser trabeculoplasty (LTP) was evaluated by measuring the incorporation of thymidine into DNA in the nuclei of trabecular meshwork cells. incorporation into DNA was analyzed by light microscopic autoradiography and by scintillation counting of trabecular extracts. Sixteen cats received argon L...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1994-04-01 00:00:00
abstract:PURPOSE:To clarify the mechanism by which bunazosin hydrochloride (BZ), a selective alpha1-adrenoceptor antagonist, increases uveoscleral outflow. METHODS:The effects of BZ on matrix metalloproteinase (MMP) activities in cultured monkey ciliary muscle cells, and on phenylephrine hydrochloride-induced constriction in b...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/00061198-200408000-00009
更新日期:2004-08-01 00:00:00
abstract:PURPOSE:Impairment of the blood-aqueous barrier in unoperated eyes with pseudoexfoliation syndrome has been demonstrated by fluorescein angiography, fluorophotometry, measurement of aqueous flare, and determination of aqueous protein. We performed noninvasive quantification of aqueous flare using the laser flare-cell m...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1999-02-01 00:00:00
abstract:PURPOSE:To compare the effect of unoprostone isopropyl 0.12% to that of timolol maleate 0.5% solution given twice daily on the diurnal curve of intraocular pressure (IOP) in patients with primary open-angle glaucoma or ocular hypertension. METHODS:In this investigator-masked, single-center, parallel-group comparison, ...
journal_title:Journal of glaucoma
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1998-12-01 00:00:00
abstract:PURPOSE:To evaluate tonometric outcomes of patients with primary angle closure glaucoma (PACG) who have undergone trabeculectomy with mitomycin C (MMC) with and without concurrent phacoemulsification and to identify risk factors for postoperative failure. PATIENTS AND METHODS:Retrospective cohort study of 44 eyes of 3...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000493
更新日期:2016-09-01 00:00:00
abstract:PRECIS:The association between primary open-angle glaucoma (POAG) and subsequent development of chronic kidney disease (CKD) was investigated using a nationwide, population-based, retrospective cohort in South Korea. POAG increases the risk of subsequent CKD development. PURPOSE:The purpose of this study was to invest...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001390
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:To assess the relative afferent pupillary defect (RAPD) by swinging flashlight as a potentially useful screening test for glaucomatous optic neuropathy. METHODS:One hundred seven subjects prospectively recruited from a mixed population of glaucomatous and nonglaucomatous patients were examined for a RAPD by 1 ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31826a9742
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:To evaluate the influence of age-related macular degeneration (AMD) on macular thickness measurement made with Fourier-domain optical coherence tomography (RTVue-OCT) to detect glaucoma. METHODS:: One nonglaucomatous eye of 79 white persons was imaged. This comprised 25 healthy eyes, 19 eyes with early/interme...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31824083e6
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of CO2 laser-assisted sclerectomy surgery (CLASS) in primary and pseudoexfoliative open-angle glaucoma. MATERIALS AND METHODS:Patients for primary filtration surgery underwent CLASS with a CO2 laser system (OT-134-IOPtiMate, IOPtima Ltd., Ramat Gan, Israel). This self-controlled system...
journal_title:Journal of glaucoma
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1097/IJG.0b013e3181f7b14f
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To investigate corneal viscoelasticity in primary open-angle glaucoma patients with and without diabetes mellitus, and to correlate corneal hysteresis (CH) with central corneal thickness (CCT). METHODS:In this cross-sectional study, 44 primary open-angle glaucoma patients [19 with diabetes (34 eyes) and 25 wit...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181b4caa1
更新日期:2010-06-01 00:00:00
abstract:PURPOSE:We explored the risk factors for glaucoma blindness among adults aged 40 years and above with primary glaucoma in Nigeria. PARTICIPANTS AND METHODS:A total of 13,591 participants aged 40 years and above were examined in the Nigeria Blindness Survey; 682 (5.02%; 95 CI, 4.60%-5.47%) had glaucoma by ISGEO's crite...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000487
更新日期:2016-10-01 00:00:00
abstract:PURPOSE:To determine the effect of cataract extraction on the glaucoma progression index (GPI) in glaucoma patients with coexisting cataract. PATIENTS AND METHODS:This is a retrospective noncomparative study. Consecutive eligible patients with glaucoma who underwent phacoemulsification alone or in combination with aug...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181b21fb9
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:To investigate the efficacy and safety of a treatment strategy with latanoprost and dorzolamide in primary pediatric glaucoma patients partially responsive to surgery. PATIENTS AND METHODS:Children with primary pediatric glaucoma having postsurgical untreated intraocular pressure (IOP) between 22 and 26 mm Hg ...
journal_title:Journal of glaucoma
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/IJG.0000000000000773
更新日期:2017-11-01 00:00:00
abstract::The recent advent of in vivo two-photon microscopy has allowed the repeat imaging of cortical structures at microscopic resolution within intact brains. Recent data obtained using this imaging technique shows that dendritic spines, the postsynaptic sites of the majority of excitatory synapses in the central nervous sy...
journal_title:Journal of glaucoma
pub_type: 杂志文章,评审
doi:10.1097/IJG.0b013e3182934a30
更新日期:2013-06-01 00:00:00